Challenges And Opportunities Of Mrna Vaccines Against Sars Cov 2

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Challenges and Opportunities of mRNA Vaccines Against SARS-CoV-2

Author : Siguna Mueller
Publisher : Springer Nature
ISBN 13 : 3031189035
Total Pages : 460 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Challenges and Opportunities of mRNA Vaccines Against SARS-CoV-2 by : Siguna Mueller

Download or read book Challenges and Opportunities of mRNA Vaccines Against SARS-CoV-2 written by Siguna Mueller and published by Springer Nature. This book was released on 2023-01-04 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an analytical look at the much debated risks and benefits of the newly developed COVID-19 mRNA-vaccines. As such, it is one of the first books to give a comprehensive overview of mRNA vaccines against COVID-19 and the only one that addresses this topic from a broad multidisciplinary background. It brings together insights from various underlying disciplines on the challenges of developing and evaluating the most suitable vaccines for mass vaccination programs enrolled throughout the world - focusing on safety and efficacy. This book should not be missing on the shelf of any biomedical researcher, epidemiologist, public health professional or clinical researcher interested in SARS-CoV2 or virology and vaccine development in general.

Trained Immunity-based Vaccines

Author : Jose Luis Subiza
Publisher : Frontiers Media SA
ISBN 13 : 2889712311
Total Pages : 195 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Trained Immunity-based Vaccines by : Jose Luis Subiza

Download or read book Trained Immunity-based Vaccines written by Jose Luis Subiza and published by Frontiers Media SA. This book was released on 2021-08-25 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

A Shot in the Arm

Author : Yossi Sheffi
Publisher : MIT CTL Media
ISBN 13 :
Total Pages : 189 pages
Book Rating : 4.9/5 (85 download)

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Book Synopsis A Shot in the Arm by : Yossi Sheffi

Download or read book A Shot in the Arm written by Yossi Sheffi and published by MIT CTL Media. This book was released on 2021-10-19 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: In A Shot in the Arm, MIT Professor Yossi Sheffi recounts the extraordinary journey to deliver Covid-19 vaccines: from scientific advancements to candidate vaccines and mass vaccination. It is a story of bold innovation, risk-taking, and teamwork as scientists, engineers, supply chain experts, manufacturers, and governments collaborated on the greatest product launch in history. The book also highlights the breathtaking potential of revolutionary mRNA technology and the vital lessons for combating other global challenges, including climate change.

Challenges and Opportunities of MRNA Vaccines Against SARS-CoV-2

Author : Siguna Mueller
Publisher :
ISBN 13 : 9783031189043
Total Pages : 0 pages
Book Rating : 4.1/5 (89 download)

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Book Synopsis Challenges and Opportunities of MRNA Vaccines Against SARS-CoV-2 by : Siguna Mueller

Download or read book Challenges and Opportunities of MRNA Vaccines Against SARS-CoV-2 written by Siguna Mueller and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Vaccinology

Author : Gregg N. Milligan
Publisher : John Wiley & Sons
ISBN 13 : 0470656166
Total Pages : 404 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Vaccinology by : Gregg N. Milligan

Download or read book Vaccinology written by Gregg N. Milligan and published by John Wiley & Sons. This book was released on 2015-02-16 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Synthetic mRNA

Author : Robert E. Rhoads
Publisher : Humana
ISBN 13 : 9781493936236
Total Pages : 0 pages
Book Rating : 4.9/5 (362 download)

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Book Synopsis Synthetic mRNA by : Robert E. Rhoads

Download or read book Synthetic mRNA written by Robert E. Rhoads and published by Humana. This book was released on 2016-05-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents detailed laboratory protocols for in vitro synthesis of mRNA with favorable properties, its introduction into cells by a variety of techniques, and the measurement of physiological and clinical consequences such as protein replacement and cancer immunotherapy. Synthetic techniques are described for structural features in mRNA that provide investigational tools such as fluorescence emission, click chemistry, photo-chemical crosslinking, and that produce mRNA with increased stability in the cell, increased translational efficiency, and reduced activation of the innate immune response. Protocols are described for clinical applications such as large-scale transfection of dendritic cells, production of GMP-grade mRNA, redirecting T cell specificity, and use of molecular adjuvants for RNA vaccines. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Synthetic mRNA: Production, Introduction into Cells, and Physiological Consequences is a valuable and cutting-edge resource for both laboratory investigators and clinicians interested in this powerful and rapidly evolving technology.

Tutorial Topics in Infection for the Combined Infection Training Programme

Author : Cheuk Yan William Tong
Publisher : Oxford University Press
ISBN 13 : 0192521772
Total Pages : 513 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Tutorial Topics in Infection for the Combined Infection Training Programme by : Cheuk Yan William Tong

Download or read book Tutorial Topics in Infection for the Combined Infection Training Programme written by Cheuk Yan William Tong and published by Oxford University Press. This book was released on 2019-07-04 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology and virology laboratories provide a diagnostic service that supports the management of patients under the care of front-line clinicians. Despite the significant overlap, laboratory expertise and clinical patient management are traditionally viewed as independent entities. Trainees in the infection disciplines of microbiology, virology, infectious diseases, and tropical medicine have until recently received separate, and as a result, limited training. To address this problem, the UK replaced the FRCPath Part 1 examination for infectious disease trainees with a combined infection training (CIT) curriculum in 2015. Based on the idea of integration and collaboration within the field, CIT links laboratory expertise to clinical patient management. Tutorial Topics in Infection for the Combined Infection Training Programme is the first book covering the complete CIT curriculum. Following the format of the CIT certificate examination, each chapter ends with three single best answer multiple choice questions accompanied by in-depth discussions. This extensive content helps students appreciate the breadth of knowledge required, emphasises how the different aspects of the field are related, and is an essential tool for those preparing for the CIT certificate examination. Written by a multi-disciplinary team of medical microbiologists, virologists, infectious disease physicians, clinical scientists, biomedical scientists, public health specialists, HIV clinicians, and infection control nurses, this well-illustrated and easy to use book offers a unique insight into infectious diseases. It is the perfect primer for further study, a starting point for medical students and professionals wishing to learn more about the different topics within the infection specialty, and ideal for biomedical scientists looking to broaden their clinical understanding of the field beyond the diagnostic test.

Vaccines against RNA Viruses

Author : Juan Carlos Saiz
Publisher : MDPI
ISBN 13 : 3039436236
Total Pages : 166 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Vaccines against RNA Viruses by : Juan Carlos Saiz

Download or read book Vaccines against RNA Viruses written by Juan Carlos Saiz and published by MDPI. This book was released on 2020-12-28 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA viruses cause animal, human, and zoonotic diseases that affect millions of individuals, as is being exemplified by the devastating ongoing epidemic of the recently identified SARS-Cov-2. For years vaccines have had an enormous impact on overcoming the global burden of diseases. Nowadays, a vast number of different approaches, from purified inactivated and live attenuated viruses, nucleic acid (DNA or RNA) based candidates, virus-like particles, subunit elements, and recombinant viruses are been employed to combat viruses. However, for many of them efficient vaccines are not yet available. This will probably change dramatically with the current Covid-19 pandemic, as a vast variety of vaccinology approaches are being tested against it, with hundreds of candidates under development, dozens of them already in clinical trials, a fact that is breaking records in vaccine development and implementation. This is becoming possible thanks to the enormous work carried out during years to have the bases for a quick response, even against unknown pathogens, in an impressive short time. Here, results obtained with different vaccine´s methodological approaches against human (HIV, HCV, HRV) animal (PRRSV, PEDV, FMDV, VHSV) and zoonotic (RVF, WNV), RNA viruses are presented by field experts.

RNAi Technology

Author : R. K. Gaur
Publisher : CRC Press
ISBN 13 : 1439873259
Total Pages : 388 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis RNAi Technology by : R. K. Gaur

Download or read book RNAi Technology written by R. K. Gaur and published by CRC Press. This book was released on 2016-04-19 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNAi technology is used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. Introducing new technology in the study of RNA

How to Prevent the Next Pandemic

Author : Bill Gates
Publisher : Vintage
ISBN 13 : 0593534492
Total Pages : 235 pages
Book Rating : 4.5/5 (935 download)

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Book Synopsis How to Prevent the Next Pandemic by : Bill Gates

Download or read book How to Prevent the Next Pandemic written by Bill Gates and published by Vintage. This book was released on 2022-05-03 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Governments, businesses, and individuals around the world are thinking about what happens after the COVID-19 pandemic. Can we hope to not only ward off another COVID-like disaster but also eliminate all respiratory diseases, including the flu? Bill Gates, one of our greatest and most effective thinkers and activists, believes the answer is yes. The author of the #1 New York Times best seller How to Avoid a Climate Disaster lays out clearly and convincingly what the world should have learned from COVID-19 and what all of us can do to ward off another catastrophe like it. Relying on the shared knowledge of the world’s foremost experts and on his own experience of combating fatal diseases through the Gates Foundation, Gates first helps us understand the science of infectious diseases. Then he shows us how the nations of the world, working in conjunction with one another and with the private sector, how we can prevent a new pandemic from killing millions of people and devastating the global economy. Here is a clarion call—strong, comprehensive, and of the gravest importance.

The Ethics of Pandemics

Author : Meredith Celene Schwartz
Publisher : Broadview Press
ISBN 13 : 1460407202
Total Pages : 164 pages
Book Rating : 4.4/5 (64 download)

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Book Synopsis The Ethics of Pandemics by : Meredith Celene Schwartz

Download or read book The Ethics of Pandemics written by Meredith Celene Schwartz and published by Broadview Press. This book was released on 2020-07-30 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: A portion of the revenue from this book’s sales will be donated to Doctors Without Borders to assist in the fight against COVID-19. The rapid spread of COVID-19 has had an unprecedented impact on modern health-care systems and has given rise to a number of complex ethical issues. This collection of readings and case studies offers an overview of some of the most pressing of these issues, such as the allocation of ventilators and other scarce resources, the curtailing of standard privacy measures for the sake of public health, and the potential obligations of health-care professionals to continue operating in dangerous work environments.

Intradermal Immunization

Author : Marcel B.M. Teunissen
Publisher : Springer Science & Business Media
ISBN 13 : 3642236901
Total Pages : 262 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Intradermal Immunization by : Marcel B.M. Teunissen

Download or read book Intradermal Immunization written by Marcel B.M. Teunissen and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Microbiology and Immunology covers diverse topics related to intradermal immunization. The chapters highlight the effectiveness of intradermal immunization in experimental animal models or in clinical practice, all supporting the view that intradermal immunization is at least as good as other immunization routes. Keeping in mind that current vaccines are not specially designed for intradermal immunization, but show comparable efficiency even at reduced dosages, this underlines the great potential for the skin as a vaccination site. Hopefully, the overview in this volume will encourage vaccine designers to focus on this promising immunization route, and in addition, to inspire them to develop vaccines that are especially optimized for intradermal immunization.

Red Book

Author : Larry K. Pickering
Publisher :
ISBN 13 : 9781581107036
Total Pages : 0 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Red Book by : Larry K. Pickering

Download or read book Red Book written by Larry K. Pickering and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed by the AAP (American Academy of Pediatrics) Committee on Infectious Diseases in conjunction with the CDC (Centers for disease control), the FDA (Food and drug administration), and other leading institutions with contributions from hundreds of physicians nationwide, the newly revised and updated 2012 Red Book continues the tradition of excellence with the latest findings and clinical recommendations on the manifestations, etiology, epidemiology, diagnosis, and treatment of more than 200 childhood conditions. [Ed.].

A Shot to Save the World

Author : Gregory Zuckerman
Publisher : Penguin
ISBN 13 : 0593420403
Total Pages : 384 pages
Book Rating : 4.5/5 (934 download)

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Book Synopsis A Shot to Save the World by : Gregory Zuckerman

Download or read book A Shot to Save the World written by Gregory Zuckerman and published by Penguin. This book was released on 2021-10-26 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: "An inspiring and informative page-turner." –Walter Isaacson Longlisted for the FT/McKinsey Business Book of the Year Award The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the Market Few were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his “bravura storytelling” (Gary Shteyngart) and “first-rate” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.

Clinical Trials in Vulnerable Populations

Author : Milica Prostran
Publisher : BoD – Books on Demand
ISBN 13 : 1789232007
Total Pages : 226 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Clinical Trials in Vulnerable Populations by : Milica Prostran

Download or read book Clinical Trials in Vulnerable Populations written by Milica Prostran and published by BoD – Books on Demand. This book was released on 2018-05-09 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book Clinical Trials in Vulnerable Populations has 12 chapters divided into 4 sections: Minority Patients, Women, Medically Compromised Patients and Clinical Trials. Contributing authors came from several countries, from Serbia to Turkey. The book was edited by Professor Milica Prostran MD, Ph.D., specialist in Clinical Pharmacology. The potential reader is shown a modern approach to clinical trials in vulnerable populations, from different points of view. The chapters deal at length and clarity with their topics. Finally, I believe, that this book I edited and reviewed with dedication will capture the attention of many readers, from medical students to practicing doctors and pharmacists. All of whom must consider this very important field of medicine: clinical trials in vulnerable patients.

Mucosal Vaccines

Author : Hiroshi Kiyono
Publisher : Elsevier
ISBN 13 : 0080537057
Total Pages : 501 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Mucosal Vaccines by : Hiroshi Kiyono

Download or read book Mucosal Vaccines written by Hiroshi Kiyono and published by Elsevier. This book was released on 1996-10-23 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. - Provides the latest views on mucosal vaccines - Applies basic principles to the development of new vaccines - Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases - Unique and user-friendly organization

The Vaccine Book

Author : Barry R. Bloom
Publisher : Academic Press
ISBN 13 : 012805400X
Total Pages : 666 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Vaccine Book by : Barry R. Bloom

Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk. - Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines - Gives new ideas about future vaccines and concepts - Introduces new vaccines and concepts - Gives ideas about challenges facing public and private industrial investors in the vaccine area - Discusses the problem of declining immunization rates and vaccine hesitancy