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Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lee E. Limbird
Publisher : Springer Science & Business Media
ISBN 13 : 9780792338390
Total Pages : 260 pages
Book Rating : 4.3/5 (383 download)
Download or read book Cell Surface Receptors: A Short Course on Theory and Methods written by Lee E. Limbird and published by Springer Science & Business Media. This book was released on 1995-12-31 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Surface Receptors: A Short Course on Theory and Methods, Second Edition is a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying principles removes the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, the basic concepts become emphasized. This volume is a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed.
Author : Krishna C. Persaud
Publisher : CRC Press
ISBN 13 : 1439871728
Total Pages : 237 pages
Book Rating : 4.4/5 (398 download)
Download or read book Neuromorphic Olfaction written by Krishna C. Persaud and published by CRC Press. This book was released on 2016-04-19 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Author : Ralph A. Bradshaw
Publisher : Academic Press
ISBN 13 : 0080920918
Total Pages : 3048 pages
Book Rating : 4.0/5 (89 download)
Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3048 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Contains over 350 chapters of comprehensive coverage on cell signaling Includes discussion on topics from ligand/receptor interactions to organ/organism responses Provides user-friendly, well-illustrated, reputable content by experts in the field
Author : Lee E. Limbird
Publisher : Springer Science & Business Media
ISBN 13 : 0387230807
Total Pages : 226 pages
Book Rating : 4.3/5 (872 download)
Download or read book Cell Surface Receptors written by Lee E. Limbird and published by Springer Science & Business Media. This book was released on 2006-06-02 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest. The study of receptors has changed considerably over the period of the publication of the three editions of this book. The cloning of several genomes makes it unlikely that preparations of receptors now or in the future will arise from their purification as trace proteins from native tissues, but rather from a myriad of molecular approaches. Nonetheless, understanding the molecular mechanisms and ultimately the in vivo biology of these receptors means that investigators will engage in molecular, cellular and ultimate in vivo strategies. It should be of value to investigators who want to identify, characterize and understand the biology of a receptor of interest.
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Tak W. Mak
Publisher : Springer Science & Business Media
ISBN 13 : 1468454064
Total Pages : 243 pages
Book Rating : 4.4/5 (684 download)
Download or read book The T-Cell Receptors written by Tak W. Mak and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of thymus-dependent cells, or T cells, in the generation of a successful immune response was first realized in the early sixties. In the follow ing two decades, a succession of elegant experiments established the antigen specificity of T cells and their ability to perform both as regulatory and effector cells. T cells were shown to be essential in most immune reactions, playing a crucial role in augmenting the activity of effector T and B cells against 'foreign' antigen, as well as in the suppression of effector activity against self antigens. The means by which T cells differentiate 'foreign' from 'self' antigens is based on their recognition of antigen almost exclusively in the context of self major histocompatibility complex products, unlike B cells, which recognize an tigen alone. It is this recognition, mediated by the T-cell receptor, that sets into motion the diverse cell-cell interactions, which control the differentiation and regulation of the immune response. Although its importance was well established, the molecular nature of the T-cell receptor remained elusive for two decades. Many hypotheses as to its structure and precise function were put forward, using immunoglobulin as a basis for conjecture, but "the Holy Grail of Immunology" remained ephemeral until three years ago. In the ensuing years, both immunologists and molecular biologists have contributed to an explosion of data unsurpassed by any previous period in the field.
Author : Michael S. Roberts
Publisher : John Wiley & Sons
ISBN 13 : 3527337261
Total Pages : 266 pages
Book Rating : 4.5/5 (273 download)
Download or read book Receptor Biology written by Michael S. Roberts and published by John Wiley & Sons. This book was released on 2016-05-02 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is geared to every student in biology, pharmacy and medicine who needs to become familiar with receptor mediated signaling. The text starts with explaining some basics in membrane biochemistry, hormone biology and the concept of receptor based signaling as the main form of communication between cells and of cells with the environment. It goes on covering each receptor superfamily in detail including their structure and evolutionary context. The last part focusses exclusively on examples where thorough knowledge of receptors is critical: pharmaceutical research, developmental biology, neurobiology and evolutionary biology. Richly illustrated, the book is perfectly suited for all courses covering receptor based signaling, regardless whether they are part of the biology, medicine or pharmacology program.
Author : Lee E. Limbird
Publisher : Springer Science & Business Media
ISBN 13 : 1475718829
Total Pages : 205 pages
Book Rating : 4.4/5 (757 download)
Download or read book Cell Surface Receptors written by Lee E. Limbird and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to serve as a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying prin ciples is intended to remove the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, it is hoped that the basic concepts can be emphasized. This book is meant to be a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed. I feit compelled to write this book for several reasons. The primary philosophical reason was to provide, in one volume, an overall perspective on the study ofcell surface receptors that describes their characterization from pharmacological studies in a whole organ or tissue bath (chapter 2) to studies of radioligand binding in isolated membrane and detergent-solubilized pre parations (chapters 3-5) and, back again, to studies in intact cells or tissues using morphological and biochemical techniques (chapter 6). It is my opinion that the ultimate understanding of the molecular basis for hormone or drug receptor interactions, and the physiological consequences of these inter actions, will require an assessment of cell surface receptor function at all of these experimental levels. In many cases an investigator may not choose to of investigation considered here.
Author : Gerhard Seifert
Publisher : Springer Science & Business Media
ISBN 13 : 3642755151
Total Pages : 525 pages
Book Rating : 4.6/5 (427 download)
Download or read book Cell Receptors written by Gerhard Seifert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date review of the morphology and pathological aspects of cell receptors, important because new therapies for various pathological conditions (genetic diseases, endocrine disorders, cancer, etc.) could be based on receptor interference.
Author : K. Christopher Garcia
Publisher : Elsevier
ISBN 13 : 0080493793
Total Pages : 547 pages
Book Rating : 4.0/5 (84 download)
Download or read book Cell Surface Receptors written by K. Christopher Garcia and published by Elsevier. This book was released on 2004-12-18 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Surface Receptors contains an extensive discussion of cell surface receptors in 11 chapters by experts in their field. As cell surface receptors are involved in almost every aspect of signaling throughout the body, the topic has been of high interest in the community in recent years. Selected Contents: Structures of Axon Guidance Molecules and Their Neuronal Receptors Shared Cytokine Signaling Receptor NKG2D and Related Immunoreceptors Inonotropic Glutamat Receptor Recognition and Activation Chemotaxis Receptors and Signaling
Author : A.G. Lee
Publisher : Elsevier
ISBN 13 : 9780080540344
Total Pages : 319 pages
Book Rating : 4.5/5 (43 download)
Download or read book Receptors of Cell Adhesion and Cellular Recognition written by A.G. Lee and published by Elsevier. This book was released on 1996-06-25 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 3 of Biomembranes covers receptors of cell adhesion and cellular recognition. Proteins in the plasma membrane of cells are heavily involved in processes of cell adhesion, but such proteins were not actually isolated and characterized until the mid-1970s. Since then, application of the methods of molecular biology has led to the recognition of four major classes of cell adhesion molecule (CAMs), the immunoglobulin super family, the cadherins, the integrins, and the selecting. A convenient system in which to study the importance of cell adhesion is in blood platelets where aggregation eventually leads to thrombus formation in a process involving a range of surface glycoproteins. Interaction with the extracellular matrix is exemplified by CD44, the receptor for hyaluronan, and a complex carbohydrate that is a major component of the extracellular matrix surrounding migrating and proliferating cells. Membrane-associated mucins have a variety of effects on cell adhesion. The super family of immunoglobulin related proteins also include the T cell receptors and the major histocompatibility complex (MHC), which, together with the receptors for immunoglobulins (the Fc receptors), are of fundamental importance in the processes of immunity. Volume 3 of Biomembranes explores the structures and functions of the molecules involved in these important functions of the cell.
Author : Pier Andrea Borea
Publisher : Springer Science & Business Media
ISBN 13 : 9048131448
Total Pages : 322 pages
Book Rating : 4.0/5 (481 download)
Download or read book A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics written by Pier Andrea Borea and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, with its 16 chapters, documents the present state of knowledge of the adenosine A receptor. It covers a wide range of information, including data from 3 studies of theoretical, molecular and cellular pharmacology, signal transduction, integrative physiology, new drug discoveries and clinical applications. It fills an important gap in the literature since no alternative source of such information is currently available. Although the A receptor is increasingly being recognized for 3 its increasing number of biological roles throughout the body and many A receptor 3 ligands have proven useful in elucidating peripheral and central pathologies, many issues remain unresolved. Moreover, research activity in this field continues to grow exponentially, resulting in a constant flow of new information. The chapters in this book cover both basic science and the relevant applications and provide an authoritative account of the current status of the field. They have enabled my goal as editor to make “A Adenosine Receptors from Cell Biology to Pharmacology and 3 Therapeutics” an up to date, scientifically excellent, reference source, attractive to basic and clinical scientists alike, a reality. Detailed understanding of the physico-chemical aspects and molecular biology of the A receptor provides a solid basis for its future development as a target for 3 adenosine-based pharmacotherapies (Chapters 2 and 3).
Author : Douglas A. Lauffenburger
Publisher : Oxford University Press
ISBN 13 : 0190283068
Total Pages : 376 pages
Book Rating : 4.1/5 (92 download)
Download or read book Receptors written by Douglas A. Lauffenburger and published by Oxford University Press. This book was released on 1996-01-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrum of receptor processes--from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testing and includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.
Author : Ralph A. Bradshaw
Publisher : Academic Press
ISBN 13 : 0123822122
Total Pages : 456 pages
Book Rating : 4.1/5 (238 download)
Download or read book Functioning of Transmembrane Receptors in Signaling Mechanisms written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2011-04-05 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. Written and edited by experts in the field, this book provides up-to-date research on transmembrane signaling entities and their initiating responses following extracellular stimulation. Articles written and edited by experts in the field Thematic volume covering effectors, cytosolic events, nuclear, and cytoplasmic events Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease
Author : Rae R. Matsumoto
Publisher : Springer Science & Business Media
ISBN 13 : 0387365141
Total Pages : 416 pages
Book Rating : 4.3/5 (873 download)
Download or read book Sigma Receptors written by Rae R. Matsumoto and published by Springer Science & Business Media. This book was released on 2007-02-15 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an update on sigma receptors, and summarizes recent advances in the medicinal chemistry, molecular biology, and cell biology of sigma receptors. It describes the functional effects mediated by these receptors and the potential clinical implications of these actions. The information is put in a historical perspective. This provides a launching point from which future studies and research directions can easily be developed.
Author : G V Sherbet
Publisher : Elsevier
ISBN 13 : 0123878195
Total Pages : 368 pages
Book Rating : 4.1/5 (238 download)
Download or read book Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy written by G V Sherbet and published by Elsevier. This book was released on 2011-07-14 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation G.V. Sherbet provides insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. The book focuses on the relationships and convergence of growth factors and their receptors in development and pathogenesis.
