Cell Hybrids

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Publisher : Academic Press
ISBN 13 : 1483270092
Total Pages : 381 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Cell Hybrids by : Nils R. Ringertz

Download or read book Cell Hybrids written by Nils R. Ringertz and published by Academic Press. This book was released on 2014-06-28 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Hybrids summarizes the methodology of cell fusion-the fusion of human, animal, and plant cells of different origins to produce cell hybrids-and surveys the main applications and current findings of the hybridization technique. The book opens with a chapter on the history cell hybridization. This is followed by separate chapters on spontaneous cell fusion, virus-induced cell fusion, the cell fusion mechanism, regulation of DNA synthesis and mitosis in heterokaryons and homokaryons, and regulatory events which occur when two cells with different nuclear activity and/or phenotype are fused with each other. Subsequent chapters deal with methods used in preparing various cell fragments and some of their properties and uses in fusion experiments; isolation of growing hybrid cells; chromosome patterns and phenotypic expression in hybrid cells; cell organelles in hybrid cells; analysis of malignancy by cell hybridization. The final chapters discuss the use of somatic cell hybridization to analyze the interaction between a number of viruses and their host cells; and the use of plant cell hybrids.

Somatic Cell Hybridization

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Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Somatic Cell Hybridization by : Richard L. Davidson

Download or read book Somatic Cell Hybridization written by Richard L. Davidson and published by . This book was released on 1974 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Somatic Cell Hybrids

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Author :
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Somatic Cell Hybrids by : Abbott

Download or read book Somatic Cell Hybrids written by Abbott and published by Oxford University Press, USA. This book was released on 1995-03 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describing the background to a technique widely used in human genetics, this study analyzes the uses of a particular type of cell culture. These uses include the mapping of human genes, a key aspect of the human genome project.

Hybridization of Somatic Cells

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Publisher : Princeton University Press
ISBN 13 : 140086822X
Total Pages : 187 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Hybridization of Somatic Cells by : Boris Ephrussi

Download or read book Hybridization of Somatic Cells written by Boris Ephrussi and published by Princeton University Press. This book was released on 2015-03-08 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its discovery in I960, the hybridization of somatic cells has evolved from a biological curiosity into an analytical method that today underlies nearly all investigations of the genetic aspects of various biological phenomena. As an eyewitness to this development from its inception forward, Boris Ephrussi here relates the history of somatic hybridization and the formation of its methodology, lie follows with a discussion of the characteristics and properties of the resultant hybrid cells. Together, these topics comprise an authoritative introduction to the principles of the technique. Dr. Ephrussi proceeds to an examination in greater detail of three specific areas of biological research to which the techniques of hybridization are currently being applied with promising consequences. Thus the major part of the book deals with applications of somatic hybridization to mammalian genetics, cell differentiation, and cancer. Originally published in 1972. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Hybridomas and Cellular Immortality

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Publisher : Springer Science & Business Media
ISBN 13 : 1461593522
Total Pages : 312 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Hybridomas and Cellular Immortality by : Baldwin H. Tom

Download or read book Hybridomas and Cellular Immortality written by Baldwin H. Tom and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to "immortalize" immunologically-useful cells by hybridization with a unique cancer cell has revolutionized serological studies and has revealed new potential applications in all fields of biological sciences. This volume presents the studies from a highly successful national symposium on Hybridomas and Cellular Immortality held November 1981 in Houston, Texas. The individual chapters exhibit the diversity of topics discussed during the meeting. These include emphasis on the origin of antibody diversity, Band T lymphocyte differentiation, applications of monoclonal antibodies in studies of histocompatibility, tumor, and viral antigens, plus the use of somatic cell hybridizations for studying T cell products. Three papers focus on the emerging methodologies of in vitro primary immunizations for both humoral and cell-mediated immunities, relevant for coupling with hybridoma technology. There is a useful mix of general (methods) and specific (applications) chapters. A unique aspect of the book is the presentation of both recent research findings with concise descriptions of the state of the art methodologies. It is anticipated that this work will be of interest to a wide audience of practioners in biomedical research. Hopefully, the information contained will foster new and imagi native ideas in hybridoma applications. Baldwin H. Tom, Ph.D. James P. Allison, Ph.D. vii CONTENTS PART L INTRODUCTION TO HYBRIDOMAS 1 Somatic Cell Hybrids and Hybridomas Baldwin H. Tom 3 1. Somatic Cell Hybrids 8 Hybridomas. • • • • • 2.

Somatic Cell Hybridization: Studies on Genetics and Development

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Publisher :
ISBN 13 :
Total Pages : 44 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Somatic Cell Hybridization: Studies on Genetics and Development by : Richard L. Davidson

Download or read book Somatic Cell Hybridization: Studies on Genetics and Development written by Richard L. Davidson and published by . This book was released on 1973 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Selection and Characterization of Somatic Cell Hybrids

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Publisher :
ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (125 download)

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Book Synopsis Selection and Characterization of Somatic Cell Hybrids by : Randal Mark Hauptmann

Download or read book Selection and Characterization of Somatic Cell Hybrids written by Randal Mark Hauptmann and published by . This book was released on 1984 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Genetic Analysis of Somatic Cell Hybrids that Lose Mouse Chromosomes

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (72 download)

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Book Synopsis A Genetic Analysis of Somatic Cell Hybrids that Lose Mouse Chromosomes by : Christine Anastasia Kozak

Download or read book A Genetic Analysis of Somatic Cell Hybrids that Lose Mouse Chromosomes written by Christine Anastasia Kozak and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

T Cell Hybridomas

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Publisher : Springer Science & Business Media
ISBN 13 : 3642685862
Total Pages : 260 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis T Cell Hybridomas by : H.v. Boehmer

Download or read book T Cell Hybridomas written by H.v. Boehmer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than ten years cell fusion techniques have been applied in studies on various lymphocyte functions. Ig expression was first studied in hybrids obtained by fusing myeloma cells with fibroblasts (1) or lymphomas (2), both of which do not produce Ig, and with Ig producing myelomas (3) or human blood lymphocytes (4). Kohler and Milstein (5) fused a myeloma with spleen cells from immunized mice. Up to 10% of the hybrids obtained secreted antibodies specific for the immunizing antigen. This suggested that plasma cells preferenti ally fused with the myeloma cells, a finding which was of enormous practical value. It was found that both Band T lymphocytes could be fused with the T cell tumor BW5147, which is however not permissive for Ig synthesis (6). A very large number of T cell hybridomas were generated by fusing BW5147 with cell populations containing in vivo or in vitro activated cells (7). The hybrids showed no specific T cell functions and binding assays for T cell receptors were not available. In particular, no hybrids were obtained which expreS1ed specific cytolytic activity that could be tested in short-term Cr release assays (8). However, the frustrations expressed about these failures, published in January, 1978 (9), were relieved by Taniguchi and Miller's publication a few months later of T cell hybridomas producing antigen-specific suppressor factors (10). Unfortunately, their hybrids rapidly lost factor production.

The Construction and Use of Interspecific Somatic Cell Hybrids in Reverse Genetics

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Publisher :
ISBN 13 :
Total Pages : 134 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Construction and Use of Interspecific Somatic Cell Hybrids in Reverse Genetics by : Mattias Höglund

Download or read book The Construction and Use of Interspecific Somatic Cell Hybrids in Reverse Genetics written by Mattias Höglund and published by . This book was released on 1992 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Electric, Hybrid, and Fuel Cell Vehicles

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Publisher : Springer
ISBN 13 : 9781071614914
Total Pages : 0 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis Electric, Hybrid, and Fuel Cell Vehicles by : Amgad Elgowainy

Download or read book Electric, Hybrid, and Fuel Cell Vehicles written by Amgad Elgowainy and published by Springer. This book was released on 2021-09-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of "Encyclopedia of Sustainability Science and Technology, Second Edition," covers the electrification of vehicles, which is key to a sustainable future of transportation in both light-duty and heavy-duty vehicle sectors to address global concerns of climate change, air pollutant emissions, energy efficiency and energy security. Vehicle electrification includes several existing and emerging technologies and powertrain architectures such as conventional hybrid electric vehicles (HEVs), plug-in hybrids with various electric driving range, short- and long-range battery electric vehicles, as well as hydrogen fuel cell electric vehicles (FCEVs). Electrification will be key to connected autonomous vehicles, which are perceived to improve mobility, increase safety, reduce energy consumption and infrastructure costs, improve productivity, decrease traffic congestion and increase customer satisfaction. While electrification of vehicle technologies is relatively mature, technology improvement and economies of scale are needed to compete against incumbent technologies and to realize their benefits in the marketplace. Significant infrastructure development is needed in the case of hydrogen fuel cell vehicles and to a lesser extent for plug-in electric vehicles. Vehicle efficiency improvement is sought through a combination of several approaches, including weight reduction, engine downsizing, increased engine compression ratio with high octane fuels, and the use of compression ignition engines with low octane fuels. Liquid hydrocarbon fuels are needed in applications where high storage energy density is required such as long-haul class-8 combination heavy-duty trucks. Shared mobility is another emerging concept that enables access to transportation services on an as-needed basis. This approach can enhance accessibility to transportation, decrease number of vehicles on the road, reduce energy use and impact on the environment, reduce cost of transportation and the need for parking, and reduce transportation time between origin and destination. In all, the reader will receive a comprehensive introduction to electric vehicles and technology trends, including energy storage, in light-, medium-, and heavy-duty sectors, as well as the infrastructure development that will be required to realize these benefits for society.

The Cells of the Body

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Publisher : CSHL Press
ISBN 13 : 9780879695330
Total Pages : 284 pages
Book Rating : 4.6/5 (953 download)

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Book Synopsis The Cells of the Body by : Henry Harris

Download or read book The Cells of the Body written by Henry Harris and published by CSHL Press. This book was released on 1995 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first scholarly history of research into the genetics of body cells, from its origins in the 19th century to the present day. Henry Harris, a well-known writer and a distinguished investigator in cell biology and cancer genetics, brings an unusually informed perspective to the technical aspects of his subject. He has written a book to be enjoyed not just by professional historians of science, but by working scientists in genetics, cell biology, and cancer research, from the graduate student level upwards. Its readers will derive a richer understanding of how and why the cells of the body are studied in the way that they are today.

Is this Cell a Human Being?

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Publisher : Springer Science & Business Media
ISBN 13 : 3642207723
Total Pages : 214 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Is this Cell a Human Being? by : Antoine Suarez

Download or read book Is this Cell a Human Being? written by Antoine Suarez and published by Springer Science & Business Media. This book was released on 2011-08-03 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central question of this book is whether or not particular cell entities of human origin ought to be considered human beings. The answer is crucial for making moral decisions for or against research and experimentation. Experts in the field discuss the production of embryonic-like pluripotent stem cells by altered nuclear transfer, parthenogenesis and reprogramming of adult somatic cells. They thoroughly analyse the biological and moral status of different cell entities, such as human stem cells, embryos and human-animal hybrid embryos, and make a decisive step towards establishing final criteria for what constitutes a human being. The topic is challenging in nature and of broad interest to all those concerned with current bioethical thought on embryonic human life and its implications for society.

Creating a New Set of Somatic Cell Hybrids to Isolate Human Chromosome 21 Expressed Sequences

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (595 download)

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Book Synopsis Creating a New Set of Somatic Cell Hybrids to Isolate Human Chromosome 21 Expressed Sequences by : Isik Yulug

Download or read book Creating a New Set of Somatic Cell Hybrids to Isolate Human Chromosome 21 Expressed Sequences written by Isik Yulug and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Somatic Cell Genetics

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Publisher : Springer Science & Business Media
ISBN 13 : 1468442562
Total Pages : 219 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Somatic Cell Genetics by : C. Thomas Caskey

Download or read book Somatic Cell Genetics written by C. Thomas Caskey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Genetics, Genomics, Proteomics, and Informatics

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Publisher : Springer Science & Business Media
ISBN 13 : 1402067534
Total Pages : 2139 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Encyclopedia of Genetics, Genomics, Proteomics, and Informatics by : George P. Rédei

Download or read book Encyclopedia of Genetics, Genomics, Proteomics, and Informatics written by George P. Rédei and published by Springer Science & Business Media. This book was released on 2008-04-25 with total page 2139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new third edition updates a best-selling encyclopedia. It includes about 56% more words than the 1,392-page second edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. It includes approximately 1,800 current databases and web servers. This encyclopedia covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, and patents. Similar integrated information is not available in textbooks or on the Internet.