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Author : Xavier F. Figueroa
Publisher : Frontiers Media SA
ISBN 13 : 288966676X
Total Pages : 197 pages
Book Rating : 4.8/5 (896 download)
Download or read book Cell Communication in Vascular Biology written by Xavier F. Figueroa and published by Frontiers Media SA. This book was released on 2021-04-07 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John D. Catravas
Publisher : IOS Press
ISBN 13 : 9789051994438
Total Pages : 312 pages
Book Rating : 4.9/5 (944 download)
Download or read book Vascular Endothelium written by John D. Catravas and published by IOS Press. This book was released on 1999 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its innovative topical approach, bestselling COMPARATIVE CRIMINAL JUSTICE SYSTEMS, 5e offers a comprehensive analysis as it compares the various criminal justice systems throughout the world using six model countries: China, England, France, Germany, Japan, and Saudi Arabia. The text illustrates the different types of law and justice systems while exploring the historical, political, economic, social, and cultural influences on each system. This unique approach examines important aspects of each type of justice system--common law, civil law, socialist law, and sacred (Islamic) law--to give students a thorough understanding of the similarities and differences of each system without overloading them with too much information. Completely up to date, the Fifth Edition includes the latest trends and issues in international juvenile justice, policing, and terrorism, including expanded coverage of such high- profile topics as human trafficking, Internet pornography, identity theft, transnational policing, and more.
Author : Bin Ren
Publisher : Frontiers Media SA
ISBN 13 : 2889742520
Total Pages : 332 pages
Book Rating : 4.8/5 (897 download)
Download or read book Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity written by Bin Ren and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lester R. Drewes
Publisher : Springer Science & Business Media
ISBN 13 : 1461529204
Total Pages : 283 pages
Book Rating : 4.4/5 (615 download)
Download or read book Frontiers in Cerebral Vascular Biology written by Lester R. Drewes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past three decades, the cerebral vasculature and its role in blood-brain transport has been an increasingly active area of investigation and learning, particularly from an anatomical and physiological point of view. However, much less is known at the molecular and cellular level about the blood-brain barrier especially regarding the macromolecules responsible for transport, the roles played by vascular wall components (endothelial cell, pericyte, smooth muscle, basement membrane), and the mechanisms regulating brain vascular-specific protein expression and their molecular alterations during development and disease. Fundamental questions still unanswered include: What are the molecular constituents of brain endothelial cell tight junctions? What are the membrane proteins responsible for transport of specific substrates? What are the molecular signals that cause glucose transporter gene expression to be 20 to 100 times greater in brain endothelial cells in vivo than in vitro? What roles do pericytes, smooth muscle cells and basement membrane have in establishing or maintaining blood-brain transport characteristics? Are brain vascular transport systems responsible for edema following injury? Are transporter systems regulated via receptor-mediated events? Do hormones or neuromodulators regulate transporter expression? What is the molecular mechanism by which plasma proteins enter the extravascular space? Are transporters asymmetrically distributed between the luminal and abluminal endothelial cell membranes? Can prodrugs or pharmacologic agents be designed as substrate analogs and be delivered to the central nervous system via existing transporters or receptors? Can new and beneficial transporters be introduced into the brain vasculature?
Author : Jahar Bhattacharya
Publisher : Springer Science & Business Media
ISBN 13 : 1592599095
Total Pages : 221 pages
Book Rating : 4.5/5 (925 download)
Download or read book Cell Signaling in Vascular Inflammation written by Jahar Bhattacharya and published by Springer Science & Business Media. This book was released on 2007-11-15 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey by leading basic and clinical researchers of the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement. The book illuminates not only the processes of lung inflammation, but also the potential for developing new therapeutic strategies to combat inflammatory lung disease.
Author : Walmore C. De Mello
Publisher : CRC Press
ISBN 13 : 9780849362576
Total Pages : 184 pages
Book Rating : 4.3/5 (625 download)
Download or read book Cell Intercommunication written by Walmore C. De Mello and published by CRC Press. This book was released on 1989-12-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important publication addresses intercellular communication in health and disease. It includes recent advances in morphology and chemical organization of gap junctions. It discusses the possible role of intercellular channels in excitable and non-excitable tissues. The book presents modulation of junctional permeability, as well as the possible role of cell communication in embryonic development and growth. The text concludes with a synthetic view of the role of gap junctions and potential implications to cardiology, oncology, and other areas of pathology. This volume is important to professionals in pharmacology, physiology, biochemistry, biomedical science, pathobiology, pathology, molecular genetics, toxicology and human development.
Author : Tiffany Lynn Johnson
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (71 download)
Download or read book Endothelial Cell Function Using a Tissue Engineered Blood Vessel Model written by Tiffany Lynn Johnson and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis is an inflammatory disease which develops focally in regions of the vasculature where there is dysfunction of endothelial cells modulated in part by shear stress from flowing blood. To address the clinical crisis of atherosclerosis, tissue engineering has focused on development of a living blood vessel substitute for use as a vascular graft in bypass surgery. Despite substantial progress in understanding the biological basis and developing clinical treatments for cardiovascular disease, critical challenges remain. As a novel strategy to improve understanding of basic human vascular biology and develop superior tissue engineered grafts, this dissertation combines the scientific and clinical approaches by using a tissue engineered blood vessel as a more physiologic in vitro model to study endothelial cell biology. Through the use of transcriptional profiling, results demonstrate significant changes in endothelial cell gene expression using the tissue engineered blood vessel model. Furthermore, the presence of a more physiologic substrate alters the cellular response to shear stress which is a critical mediator of vascular pathology. A case study of endothelial cell function in this system focuses on cell-cell communication through gap junctions. Endothelial cell connexins which form gap junctions are shown to be differentially regulated by substrate and shear stress. Moreover, gap junction communication between endothelial cells is modulated by the mechanical environment. Studies using RNA interference to knockdown expression of individual connexin isotypes demonstrate integrated regulation of connexins yet unique roles in endothelial cell function. Collectively, results exemplify the sensitivity of endothelial cell phenotype to substrate and shear stress and underline the importance of using more physiologic models in the study of basic cell biology.
Author : Hellmut G. Augustin
Publisher : Springer Science & Business Media
ISBN 13 : 3642187250
Total Pages : 381 pages
Book Rating : 4.6/5 (421 download)
Download or read book Methods in Endothelial Cell Biology written by Hellmut G. Augustin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field of vascular biology in general requires in vitro and in vivo techniques in order to address the complex questions. Methods in Endothelial Cell Biology is a comprehensive practical "how-to"-guide summarizing the most relevant established techniques as well as a number of new emerging techniques. Easy-to-follow reliable protocols provide a useful lab bench resource for the experienced researcher and newcomer to the field.
Author : Mirko HH Schmidt
Publisher : Springer
ISBN 13 : 1493929070
Total Pages : 402 pages
Book Rating : 4.4/5 (939 download)
Download or read book Endothelial Signaling in Development and Disease written by Mirko HH Schmidt and published by Springer. This book was released on 2015-10-08 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys healthy and diseased vascular systems in a multitude of model organisms and systems. It explores a plethora of functions, characteristics, and pathologies of the vascular system such as angiogenesis, fibroblast growth factor signaling, lymphangiogenesis, junctional signaling, the extracellular matrix, vascular permeability, leukocyte extravasation, axon guidance factors, the angiopoietin system, and chronic obstructive lung disease. Following a preface from leading researcher Dr. Holger Gerhardt, the text is divided into three sections- the first examining the development of the vascular system in a variety of contexts, the second delving into its homeostatic characteristics, and the third discussing its pathophysiologies. The sixteen chapters, which represent international clinical and research perspectives, highlight the importance of molecular and signaling pathways for translational basic science and clinical medicine. Additionally, the text explores new and exciting fields in vascular biology research. Comprehensive in both content and approach, Vascular Signaling in Health and Disease is ideal for graduate students, researchers, and clinicians interested in vascular biology, pneumology, and molecular biology.
Author : Walmor DeMello
Publisher : Springer Science & Business Media
ISBN 13 : 1468422839
Total Pages : 262 pages
Book Rating : 4.4/5 (684 download)
Download or read book Intercellular Communication written by Walmor DeMello and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress made in the last 20 years clearly indicates that the cell surface is an extremely dynamic structure involved in fundamental processes such as cell motility, innervation, and cell adhesion. Of particular interest is the finding that, in several tissues, the cell surface is differen tiated at the intercellular region, thereby providing communicating chan nels between apposing cells. Although our actual knowledge of the precise structures and mecha in the complex process of intercellular communication is still nisms involved scanty, evidence has been presented that ions and molecules diffuse from cell to cell, establishing a physiological continuum. Embryonic differentia tion, cell growth, neoplasia, electrical synchronization in nerve and mus cles, as well as immune response seem to be related to ceIl communication. In organizing this volume, it has been our intention to provide the reader with an actual review of the processes involved in intercellular communication in normal tissues as well as in neoplasia. We sincerely believe that the opinions and experiences described herein will be of help in establishing new perspectives for the future of this exciting new field of cell biology. We wish to thank all the colleagues who joined us in the organization of this volume, as well as Plenum Publishing Corporation for making its appearance possible.
Author : Walmor C. De Mello
Publisher : Springer Science & Business Media
ISBN 13 : 146131917X
Total Pages : 383 pages
Book Rating : 4.4/5 (613 download)
Download or read book Cell-to-Cell Communication written by Walmor C. De Mello and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9789462951969
Total Pages : 182 pages
Book Rating : 4.9/5 (519 download)
Download or read book Signaling in Vascular Biology written by and published by . This book was released on 2015 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Evgenia Gerasimovskaya
Publisher : Springer Science & Business Media
ISBN 13 : 9048134358
Total Pages : 240 pages
Book Rating : 4.0/5 (481 download)
Download or read book Extracellular ATP and adenosine as regulators of endothelial cell function written by Evgenia Gerasimovskaya and published by Springer Science & Business Media. This book was released on 2010-04-26 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis. This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication. This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and pathological conditions, i.e. pregnancy, hypoxia, hypertension, inflammation and diabetes. In the book’s 12 chapters, the role of purinergic signaling in endothelium-dependent tissue perfusion, regulation of endothelial barrier function, and angiogenesis are discussed. The mechanisms of ATP release and its role in intercellular communication are also presented. In addition, the book provides the most up to date mechanisms of extracellular nucleotide metabolism by purine-converting ecto-enzymes and their contribution to purinergic signaling in endothelial cells originating from various vascular beds. This book is a valuable resource for biomedical research scientists, clinical scientists, graduate students and health science professionals interested in the mechanisms of extracellular purine function in endothelial cells under physiologic and pathologic conditions.
Author : Marc Thiriet
Publisher : Springer Science & Business Media
ISBN 13 : 1461419913
Total Pages : 988 pages
Book Rating : 4.4/5 (614 download)
Download or read book Signaling at the Cell Surface in the Circulatory and Ventilatory Systems written by Marc Thiriet and published by Springer Science & Business Media. This book was released on 2011-12-14 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 3 is devoted to the set of mediators of the cell surface, especially ion and molecular carriers and catalytic receptors that, once liganded and activated, initiate signal transduction pathways. Intracellular cascades of chemical reactions trigger the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Primary mediators are included in models of regulated cellular processes, but multiple secondary signaling components are discarded to allow simple, representative modeling and to manage their inverse problems.
Author : Ernesto Oviedo-Orta
Publisher : CRC Press
ISBN 13 : 1439862583
Total Pages : 370 pages
Book Rating : 4.4/5 (398 download)
Download or read book Connexin Cell Communication Channels written by Ernesto Oviedo-Orta and published by CRC Press. This book was released on 2013-03-22 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communicati
Author : Rody P. Cox
Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.F/5 ( download)
Download or read book Cell Communication written by Rody P. Cox and published by . This book was released on 1974 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
