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Case Reports In Gastrointestinal Cancers 2022
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Book Synopsis Case Reports in Gastrointestinal Cancers : 2022 by : Pashtoon Murtaza Kasi
Download or read book Case Reports in Gastrointestinal Cancers : 2022 written by Pashtoon Murtaza Kasi and published by Frontiers Media SA. This book was released on 2023-12-08 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic aims to collect all the Case Reports submitted to the Gastrointestinal Cancers sections. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.
Book Synopsis Women in Gastrointestinal Cancers, volume II: 2022 by : Nadia M. Hamdy
Download or read book Women in Gastrointestinal Cancers, volume II: 2022 written by Nadia M. Hamdy and published by Frontiers Media SA. This book was released on 2023-06-08 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Case Reports in Breast Cancer : 2022 by : Risal Djohan
Download or read book Case Reports in Breast Cancer : 2022 written by Risal Djohan and published by Frontiers Media SA. This book was released on 2024-01-03 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Methods in gastrointestinal cancers by : Shuyun Rao
Download or read book Methods in gastrointestinal cancers written by Shuyun Rao and published by Frontiers Media SA. This book was released on 2023-05-16 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Reviews in Gastrointestinal Cancers by : Fabrizio Bronte
Download or read book Reviews in Gastrointestinal Cancers written by Fabrizio Bronte and published by Frontiers Media SA. This book was released on 2023-08-02 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Gastrointestinal Cancer Immunotherapy: from Drug Resistance Mechanisms to Overcoming Strategies by : Xiaofang Che
Download or read book Gastrointestinal Cancer Immunotherapy: from Drug Resistance Mechanisms to Overcoming Strategies written by Xiaofang Che and published by Frontiers Media SA. This book was released on 2023-06-15 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal (GI) cancers, including gastric cancer, colon cancer, liver cancer, esophageal cancer, and pancreatic cancer, seriously threaten the health of human beings worldwide with a high rate of morbidity and mortality. The clinical successes achieved with immune checkpoint inhibitors (ICIs) targeting PD-1/PD-L1 and CTLA-4 have opened a new cancer therapy era and brought new hope to cancer patients. However, the overall response rate (ORR) of ICI monotherapy in the non-selective population is only about 20%, in which some patients subsequently develop immunotherapy resistance. Moreover, the remaining 70-80% of patients displayed primary resistance to ICIs, and a few patients even experienced hyper progression disease (HPD). Although PD-L1 expression, mismatch repair deficient (MMRd), high tumor mutational burden (TMB-H) , high homologous recombination deficiency (HRD), and tumor infiltrated immune cells (TILs) are known as effective biomarkers for immunotherapy, growing studies have reported that ICIs could not improve the OS of all patients with PD-L1 expression higher than 50%, and the ORR of MSI-H patients was only about 60%, whereas some patients with low PD-L1 expression or MSS could still benefit from immunotherapy, indicating the complexity of ICI resistance. Therefore, it is of great importance and significance to explore the prediction biomarkers for primary or acquired immunotherapy resistance and elucidate their underlying molecular mechanisms and develop reversal strategies. Due to the multiple steps of the cancer immune cycle and complex immune microenvironment, any disorders of immune cell infiltration or T cell activation, such as lack of antigens and/or their presentation, lack of response to antigen presentation, and T cell priming, could contribute to ICI resistance. The combination with anti-angiogenesis therapy, radiotherapy, chemotherapy, and other ICIs has improved the efficacy of ICI therapy to some extent in the clinic. Although numerous studies related to ICI resistance were reported in GI cancers, due to the strong spatial/temporal heterogeneity and the complex immune microenvironment in different kinds of GI cancers and different individuals, many questions about ICI resistance and reversal strategies remain unsolved. The aim of this Research Topic is to provide a forum to exhibit the latest research achievement related to the exploration of biomarkers for immunotherapy resistance including HPD and the underlying molecular mechanisms, as well as the development of reversal strategies in GI cancers. We hope this Research Topic will lead to a better understanding of precision cancer immunotherapy and provide useful clues for clinical application to benefit more GI cancer patients with immunotherapy.
Book Synopsis Precision Medicine in Gastrointestinal Cancers by : Afsaneh Barzi
Download or read book Precision Medicine in Gastrointestinal Cancers written by Afsaneh Barzi and published by Frontiers Media SA. This book was released on 2023-09-01 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision medicine is the main emphasis in healthcare after recognizing the importance to integrate the clinical data with the molecular data of a specific disease. The term was first introduced in 2015 in which the Precision Medicine Initiative was initiated with the final aim to provide targeted therapy with high efficacy and less toxicity. Precision medicine plays an increasingly important in gastrointestinal cancers. Gastrointestinal cancers are divided into the upper (esophagus, stomach) and lower part (hepatobiliary and colon) of the gastrointestinal system. We would like to explore the latest era of integrative therapeutic target in gastrointestinal cancers taking into consideration of various aetiologies including genetic and exposome (dietary factors, microbial, hormonal, environmental insults) and their interactions with the host microenvironment.
Book Synopsis Angiogenesis blockade for the treatment of gastrointestinal cancer by : Zhigang Bai
Download or read book Angiogenesis blockade for the treatment of gastrointestinal cancer written by Zhigang Bai and published by Frontiers Media SA. This book was released on 2023-03-07 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinicopathological Factors and Staging in Gastrointestinal Cancers by : Qi Liu
Download or read book Clinicopathological Factors and Staging in Gastrointestinal Cancers written by Qi Liu and published by Frontiers Media SA. This book was released on 2023-05-02 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Case Reports in Surgical Oncology: 2022 by :
Download or read book Case Reports in Surgical Oncology: 2022 written by and published by Frontiers Media SA. This book was released on 2024-02-20 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic aims to collect all the Case Reports submitted to the Surgical Oncology section. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.
Book Synopsis Staging Laparoscopy by : P. Hohenberger
Download or read book Staging Laparoscopy written by P. Hohenberger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.
Book Synopsis Disputes and Challenges of Immune Checkpoint Inhibitors in Gastrointestinal Cancers by : Hongwei Yao
Download or read book Disputes and Challenges of Immune Checkpoint Inhibitors in Gastrointestinal Cancers written by Hongwei Yao and published by Frontiers Media SA. This book was released on 2024-05-15 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, immune checkpoint inhibitors (ICIs) have received a lot of attention to treat gastrointestinal cancers. Compared with traditional treatments, immunotherapy can kill cancer cells by activating the antitumor immunity, the specific recognition of cancer antigens preventing normal cells from being attacked. However, the application of ICIs is accompanied by a series of specific toxic reactions caused by the functional stimulation of the immune system, which are called immune-related adverse events (irAEs). Early identification and timely intervention to handle irAEs are usually required to maximize the therapeutic effect of ICIs. In addition, related surgical complications after neoadjuvant immunotherapy is increasingly reported. Thus, although immunotherapy has shown obvious advantages in the clinical treatment of gastrointestinal cancers, the safety and potential risks of such treatment have to be considered. Many clinical studies have shown that cancer patients receiving neoadjuvant immunotherapy experience different degrees of immune-inflammatory reaction, immune disorders, immune-related pneumonia, and other adverse events. In addition, some patients suffering from irAEs during the treatment have to face a delayed operation or even lose the opportunity to be operated. Finally, because the clinical imaging manifestations of immunotherapy are complex and diverse, the imaging evaluation criteria have so far not been standardized. The aim of this Research Topic is to report disputes and challenges of immune checkpoint inhibitors in gastrointestinal cancers. We welcome original research articles, Review articles, Mini Reviews, and Case reports. Preferred topics include but are not limited to the following: • Timely discovery of immune-related adverse events during immunotherapy • Identification and differentiation between immune-related adverse events and adverse drug events • Treatment and drug withdrawal timing upon immune-related adverse events • Management of related surgical complications after neoadjuvant immunotherapy • Imaging evaluation criteria or methods of immunotherapy efficacy
Book Synopsis Principles of Immunotherapy in Breast and Gastrointestinal Cancers by : Michele Ghidini
Download or read book Principles of Immunotherapy in Breast and Gastrointestinal Cancers written by Michele Ghidini and published by Elsevier. This book was released on 2024-08-20 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance and New Sensitization Strategies presents updated research findings on immunotherapy, with special focus on the mechanisms of resistance of those cancer types and how to overcome them. The book discusses topics such as tumor cell-intrinsic and extrinsic mechanisms of cancer resistance to immunotherapy; the role of currently available biomarkers; strategies to overcome therapeutic resistance; sensitizing agents for cancer resistance to cell mediated immunotherapy; and Immunotherapeutic approaches, mechanisms of resistance and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer. It is a valuable resource for researchers, students and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it. - Presents relevant findings on immunotherapy for breast and GI cancer types in a synthetic and didactic way for easy consult - Describes resistance mechanisms of those cancer types and how to overcome them to improve immunotherapy outcomes - Encompasses several diagrams and figures to help readers get a clearer picture of the research findings and how they can be applied to the clinical setting
Book Synopsis Case Reports in Cancer Imaging and Image-directed Interventions : 2022 by : Marco Ravanelli
Download or read book Case Reports in Cancer Imaging and Image-directed Interventions : 2022 written by Marco Ravanelli and published by Frontiers Media SA. This book was released on 2023-12-12 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic aims to collect all the Case Reports submitted to the Cancer Imaging and Image-directed Interventions section. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.
Book Synopsis Biomarkers, Functional Mechanisms, and Therapeutic Potentials in Gastrointestinal Cancers by : Zequn Li
Download or read book Biomarkers, Functional Mechanisms, and Therapeutic Potentials in Gastrointestinal Cancers written by Zequn Li and published by Frontiers Media SA. This book was released on 2023-11-17 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant changes in diet, environment, and population increase gastrointestinal cancer morbidity. A growing number of novel biomarkers and underlying mechanisms are being elucidated, some of which may even conflict with assumptions of past decades. Therefore, collecting recent findings on novel diagnostic/prognostic factors, biomarkers, and/or risk factors in gastrointestinal cancers is a prerequisite for a better understanding of the disease. Despite remarkable progressions in surgical treatments and chemotherapies, the prognosis of gastrointestinal cancer is far from satisfactory due to the high occurrence of drug resistance. Based on the identification of novel biomarkers as well as their underlying mechanisms, targeted drug development will provide significant complementary therapeutic effects to conventional chemoradiotherapies. High-throughput methods such as next-generation sequencing on RNA level and mass spectrometry on protein/lipid/metabolite level serve as efficient strategies for biomarker identification and drug development. This Research Topic aims at presenting recent advances on gastrointestinal cancer biomarkers and their underlying functional mechanisms, providing a better understanding of carcinogenesis, tumor progression, tumor relapse, as well as drug resistance. This will subsequently contribute to the development of novel therapeutic interventions targeting gastrointestinal cancers, thus improving patients' outcomes.
Book Synopsis Chemo-resistance in Gastrointestinal Cancers by : Xia Li
Download or read book Chemo-resistance in Gastrointestinal Cancers written by Xia Li and published by Frontiers Media SA. This book was released on 2022-03-30 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diagnostic Pathology: Soft Tissue Tumors E-Book by : Matthew R. Lindberg
Download or read book Diagnostic Pathology: Soft Tissue Tumors E-Book written by Matthew R. Lindberg and published by Elsevier Health Sciences. This book was released on 2023-09-06 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering the wide range of often difficult-to-diagnose variants and subtypes in soft tissue tumors, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the fourth edition of Diagnostic Pathology: Soft Tissue Tumors is a visually stunning, one-stop resource for every practicing pathologist, oncologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. - Provides up-to-date, comprehensive coverage of soft tissue pathology combined with accurate, concise clinicopathologic descriptions, helping you quickly identify tumors and establish actionable diagnoses - Contains hundreds of chapters with separate Benign, Intermediate, and Malignant sections to provide the fullest diagnostic picture possible - Contains new chapters covering the recently recognized EWSR1::SMAD3 fibroblastic tumor, plexiform myofibroblastoma, anastomosing hemangioma, myxoid pleomorphic liposarcoma, and more - Includes details throughout on new immunostains and molecular genetics and testing - Features an image-rich layout with more than 4,500 print and online-only images—including high-quality photomicrographs, gross photographs, radiologic images, and detailed medical illustrations—to make tumor identification and diagnosis faster and easier - Provides an organized framework that includes "Approach to Diagnosis" chapters designed to help you successfully recognize and diagnose challenging soft tissue tumors with the availability of common patterns and histologic features - Includes updates based on the most recent WHO Classification of Tumors: Soft Tissue and Bone Tumors - Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care - Includes an eBook version that enables you to access all text, figures, and references with the ability to search, customize your content, make notes and highlights, and have content read aloud
