Principles of Cardiac Toxicology

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Publisher : CRC Press
ISBN 13 : 9781439805367
Total Pages : 714 pages
Book Rating : 4.8/5 (53 download)

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Book Synopsis Principles of Cardiac Toxicology by : Steven I. Baskin

Download or read book Principles of Cardiac Toxicology written by Steven I. Baskin and published by CRC Press. This book was released on 1991-09-23 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: What chemicals are poisonous to the heart and why are they toxic? Find out by reading Principles of Cardiac Toxicology. Certain chemicals can produce toxicity by interacting with elements of the cardiovascular system. This book presents the anatomical, physiological, biochemical, and pathological basis for this interaction and describes the

Cardiovascular Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 9780367386955
Total Pages : 684 pages
Book Rating : 4.3/5 (869 download)

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Book Synopsis Cardiovascular Toxicology by : Daniel Acosta

Download or read book Cardiovascular Toxicology written by Daniel Acosta and published by CRC Press. This book was released on 2019-08-30 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio and vascular toxicity, such as principles of myocardial cell injury and key methods of assessing cardiovascular function. New developments include: expanded chapter on passive smoking, which includes adverse effects of smoking, and the effects of secondary smoke new chapter on the negative effects from environmental chemicals on the cardiovascular system chapters covering antibacterial agents and endotoxins include new information on cardiovascular toxicity of antimicrobials, as well as anti-viral agents, antibacterial agents, and other agents

Principles of Cardiac Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1439805369
Total Pages : 703 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Principles of Cardiac Toxicology by : Steven I. Baskin

Download or read book Principles of Cardiac Toxicology written by Steven I. Baskin and published by CRC Press. This book was released on 1991-09-23 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: What chemicals are poisonous to the heart and why are they toxic? Find out by reading Principles of Cardiac Toxicology. Certain chemicals can produce toxicity by interacting with elements of the cardiovascular system. This book presents the anatomical, physiological, biochemical, and pathological basis for this interaction and describes the

Heart and Toxins

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Author :
Publisher : Elsevier
ISBN 13 : 0124165990
Total Pages : 668 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Heart and Toxins by : Dr. Meenakshisundaram Sundaram Ramachandran

Download or read book Heart and Toxins written by Dr. Meenakshisundaram Sundaram Ramachandran and published by Elsevier. This book was released on 2014-08-12 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. - Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins - Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail - Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging - Enables you to manage multiple clinical cases of cardiovascular toxicity - Outlined conclusions at the end of each chapter providing "key learning points to help you organize the chapter's details without losing insight

Cardiac Toxicology

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Author :
Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Cardiac Toxicology by :

Download or read book Cardiac Toxicology written by and published by . This book was released on 1981 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiovascular Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1420044745
Total Pages : 730 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Cardiovascular Toxicology by : Daniel Acosta

Download or read book Cardiovascular Toxicology written by Daniel Acosta and published by CRC Press. This book was released on 2008-09-04 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio and vascular toxicity, such as principles of myocardial cell injury and key methods of assessing cardiovascular function.New developments include:expanded chapter on passive

CARDIAC TOXICOLOGY

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis CARDIAC TOXICOLOGY by : Tibor Balazs

Download or read book CARDIAC TOXICOLOGY written by Tibor Balazs and published by Springer. This book was released on 1981-08-26 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiotoxicity of Non-Cardiovascular Drugs

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780470660386
Total Pages : 360 pages
Book Rating : 4.6/5 (63 download)

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Book Synopsis Cardiotoxicity of Non-Cardiovascular Drugs by : Giorgio Minotti

Download or read book Cardiotoxicity of Non-Cardiovascular Drugs written by Giorgio Minotti and published by John Wiley & Sons. This book was released on 2010-03-25 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals.In recent years a number of non-cardiac blockbuster drugs such as terfenadine have been withdrawn from major markets because of cardiotoxicity concerns, while other drugs have either been withdrawn prior to marketing or required labelling changes that significantly restricted their use. In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is paid to the preclinical screening of drug cardiotoxicity. Topics include: metabolic targets of cardiotoxicity regulatory aspects translating molecular mechanisms into clinical trials structure-activity relationships in arrhythmias by antihistamines and psychoactive drugs cardiovascular toxicity of antitumor drugs cardiovascular toxicities of non-steroidal anti-inflammatory drugs cardiovascular toxicities of antiretroviral therapies Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.

Cardiovascular Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 0203361458
Total Pages : 592 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Cardiovascular Toxicology by : Bob Sproull

Download or read book Cardiovascular Toxicology written by Bob Sproull and published by CRC Press. This book was released on 2001-07-19 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acosta's popular volume provides information on cardiovascular toxicology for clinicians, public health officials, industrial and experimental toxicologists, as well other interested professionals. This new edition highlights major advancements on the molecular aspects of toxicity to the cardiovascular system, including genomics information where a

Principles of Cardiac Toxicology

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Author :
Publisher :
ISBN 13 : 9780936923482
Total Pages : 500 pages
Book Rating : 4.9/5 (234 download)

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Book Synopsis Principles of Cardiac Toxicology by : Steven I. Baskin

Download or read book Principles of Cardiac Toxicology written by Steven I. Baskin and published by . This book was released on 1990-05 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: What chemicals are poisonous to the heart and why are they toxic? Find out by reading Principles of Cardiac Toxicology. Certain chemicals can produce toxicity by interacting with elements of the cardiovascular system. This book presents the anatomical, physiological, biochemical, and pathological basis for this interaction and describes the classes of chemicals known to produce cardiovascular toxicity. Characteristics of potential antidotes are also discussed. Clinicians and researchers will discover that this volume is an essential guide to understanding factors that could contribute to cardiovascular health and disease. Cardiologists, emergency room physicians, intensive care nurses, consulting pharmacists, and basic medical scientists will also benefit from this comprehensive work.

Cardiotoxicity

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Publisher : BoD – Books on Demand
ISBN 13 : 1789842379
Total Pages : 164 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Cardiotoxicity by : Wenyong Tan

Download or read book Cardiotoxicity written by Wenyong Tan and published by BoD – Books on Demand. This book was released on 2018-11-14 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.

Cardiotoxicity of Oncologic Treatments

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Publisher : BoD – Books on Demand
ISBN 13 : 9535102737
Total Pages : 198 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Cardiotoxicity of Oncologic Treatments by : Manuela Fiuza

Download or read book Cardiotoxicity of Oncologic Treatments written by Manuela Fiuza and published by BoD – Books on Demand. This book was released on 2012-03-28 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.

Anticancer Treatments and Cardiotoxicity

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Publisher : Academic Press
ISBN 13 : 0128026472
Total Pages : 483 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Anticancer Treatments and Cardiotoxicity by : Patrizio Lancellotti

Download or read book Anticancer Treatments and Cardiotoxicity written by Patrizio Lancellotti and published by Academic Press. This book was released on 2016-11-11 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment

Cardiac Drug Safety

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Publisher : World Scientific
ISBN 13 : 9814317454
Total Pages : 189 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Cardiac Drug Safety by : Matthew J. Killeen

Download or read book Cardiac Drug Safety written by Matthew J. Killeen and published by World Scientific. This book was released on 2012 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ensuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug-induced heart rhythm abnormalities, remains an important cause of pipeline attrition and has resulted in countless major product recalls or label changes. The risk of encountering this major adverse event continues to shape the drug development and regulatory landscape. Extensive research over the past decade has shed light on the root causes of arrhythmias that are triggered by medications and has helped drive, and optimize, drug safety testing. However, current cardiac safety platforms have several limitations and there remains a pressing unmet need to improve the predictive power of today's drug safety tests. Fundamental to addressing the problem of drug-induced arrhythmias, and to reducing the impact of this safety signal on drug development, is a complete understanding of how these events may arise, what cardiac safety tests are currently used, and what opportunities there are to enhance patient safety and reduce the risk of detecting cardiac toxicity in later stages of product commercialization. By introducing the reader to these core concepts, this book delivers key insight into the increasingly important and dynamic field of cardiac safety.

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology

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Publisher : Academic Press
ISBN 13 : 0323904629
Total Pages : 278 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology by : Imteyaz Qamar

Download or read book Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology written by Imteyaz Qamar and published by Academic Press. This book was released on 2022-05-26 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death. - Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology - Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity - Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications

ADMET for Medicinal Chemists

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Publisher : John Wiley & Sons
ISBN 13 : 0470922818
Total Pages : 454 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis ADMET for Medicinal Chemists by : Katya Tsaioun

Download or read book ADMET for Medicinal Chemists written by Katya Tsaioun and published by John Wiley & Sons. This book was released on 2011-02-15 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.

Cardiovascular Toxicology, Third Edition

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Author :
Publisher : CRC Press
ISBN 13 : 9781134536313
Total Pages : 616 pages
Book Rating : 4.5/5 (363 download)

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Book Synopsis Cardiovascular Toxicology, Third Edition by : Daniel Acosta

Download or read book Cardiovascular Toxicology, Third Edition written by Daniel Acosta and published by CRC Press. This book was released on 2003-09-02 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acosta's popular volume provides information on cardiovascular toxicology for clinicians, public health officials, industrial and experimental toxicologists, as well other interested professionals. This new edition highlights major advancements on the molecular aspects of toxicity to the cardiovascular system, including genomics information where appropriate. The book is divided into five sections: an introduction that emphasizes the need to explore biological mechanisms as factors in the toxicity of chemicals and drugs to the cardiovascular system, followed by sections addressing methods, principles of cell injury, cardiotoxicity of chemical agents, and vascular toxicity. The editor and all contributing authors are well established experts in their respective fields thus ensuring Cardiovascular Toxicology as the most authoritative and up-to-date review of this area of systematic toxicology.