Cardiac Energetics

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Cardiac Energetics

Author : R. Jacob
Publisher : Springer Science & Business Media
ISBN 13 : 3662112892
Total Pages : 410 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis Cardiac Energetics by : R. Jacob

Download or read book Cardiac Energetics written by R. Jacob and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessment of cardiac energetics at the level of ATP-synthesis, chemomechanical energy transformation and whole organ dynamics as a function of haemodynamic load, ventricular configuration and oxygen- and substrates supply is basic to understanding cardiac function under physiological and pathophysiological (hypertrophy, hypoxia, ischaemia and heart failure) conditions. Moreover, cardiac energetics should be an important consideration in the choice and application of drugs especially in the case of vasodilators, inotropic agents and in cardioprotective measures. Only by considering energetics at the subcellular, cellular, and whole-heart level we can arrive at a better understanding of cardiac performance and ultimately better clinical judgement and drug therapy. Quantification of myocardial energetics will also help to determine the optimal time for surgical interventions such as valvular replacement or aneurysm resection. The present volume is the outcome of an international symposium on cardiac energetics held in Gargellen/Montafon (Austria), June 1986. The contributions will certainly help bridge the existing gap between basic research involving isolated structures and that involving the whole organ, on the one hand, and render the results derived from basic research applicable to clinical problems, on the other hand.

Cardiac Energetics: From Emax to Pressure-Volume Area

Author : Martin M. LeWinter
Publisher : Springer Science & Business Media
ISBN 13 : 1461520215
Total Pages : 291 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cardiac Energetics: From Emax to Pressure-Volume Area by : Martin M. LeWinter

Download or read book Cardiac Energetics: From Emax to Pressure-Volume Area written by Martin M. LeWinter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the progress in cardiac energetics in recent years has been spurred by the pressure-volume area concept, the natural extension into energetics of earlier pioneering work delineating the time-varying elastance framework for ventricular contraction. The book draws together a broad spectrum of researchers - basic, applied and clinical - having a shared interest in the energetics of cardiac muscle and ventricle, providing an overview of the current state of the art.

Cardiac Energetics

Author : Robert Jacob
Publisher : Springer
ISBN 13 : 9783798507340
Total Pages : 425 pages
Book Rating : 4.5/5 (73 download)

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Book Synopsis Cardiac Energetics by : Robert Jacob

Download or read book Cardiac Energetics written by Robert Jacob and published by Springer. This book was released on 1987-01-01 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiac Energetics

Author : Robert Jacob
Publisher : Springer Verlag
ISBN 13 : 9780387912943
Total Pages : 425 pages
Book Rating : 4.9/5 (129 download)

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Book Synopsis Cardiac Energetics by : Robert Jacob

Download or read book Cardiac Energetics written by Robert Jacob and published by Springer Verlag. This book was released on 1987 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiac Energy Metabolism in Health and Disease

Author : Gary D. Lopaschuk
Publisher : Springer
ISBN 13 : 1493912275
Total Pages : 301 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Cardiac Energy Metabolism in Health and Disease by : Gary D. Lopaschuk

Download or read book Cardiac Energy Metabolism in Health and Disease written by Gary D. Lopaschuk and published by Springer. This book was released on 2014-08-22 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Mitochondrial Medicine

Author : Volkmar Weissig
Publisher :
ISBN 13 : 9781071612705
Total Pages : 468 pages
Book Rating : 4.6/5 (127 download)

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Book Synopsis Mitochondrial Medicine by : Volkmar Weissig

Download or read book Mitochondrial Medicine written by Volkmar Weissig and published by . This book was released on 2021 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine. Volume III guides readers through chapters on intercellular mitochondrial transfer, Cytoplasmic transfer methods, Ndufs4 knockout mouse, in vivo assessment of mitochondrial oxygen consumption, mitochondrial network analysis by imaging, mitochondrial respiration in platelets, Heterologous Inferential Analysis (HIA), bioenergetic profiling, integrative methods for studying cardiac energetics, and isolation and deep sequencing of mitochondrial DNA.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Mitochondrial Medicine, Second Edition, Volume 3: Manipulating Mitochondria and Disease- Specific Approaches aims to be a comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine.

Heart Perfusion, Energetics, and Ischemia

Author : Leopold Dintenfass
Publisher : Springer Science & Business Media
ISBN 13 : 1475703937
Total Pages : 697 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Heart Perfusion, Energetics, and Ischemia by : Leopold Dintenfass

Download or read book Heart Perfusion, Energetics, and Ischemia written by Leopold Dintenfass and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: The principal purpose of a NATO (North Atlantic Treaty Organization) Advanced Research Workshop, a part of the NATO Advanced Study Institutes Programme, is to: (a) exchange thoughts at the frontiers of knowledge or at the frontiers of two (or more) fields or sectors; (b) review and assess the state of the art; (c) formulate recommendations for future research directions; (d) formulate plans for large international scientific experiments. The aim of the ARW on "Microvascular, rheological, metabolic and heat-transfer aspects of the heart: relation to ischaemia and thrombosis", convened in Chateau de Bonas, July 4-11, 1982, was to describe functions and performance of the heart in an interdisciplin ary effort, involving cardiologists, pathologists, biochemists, haemorheologists, physiologists, pharmacologists and bioengineers; to explore interactions between such subfields as blood rheology, micro circulation and ischaemia of the myocardium, heat transfer, heat work and performance as a pump, effect of -metabolites and ion transfer, mechanism of sudden death, protein synthesis and protein molecular transformations. One of the purposes of the Convenor was to relate clinical haemorheology to the heart energetics and heart metabolism. This was only partly established, as difficulties of communications between different fields, difficulties of semantics and of specialized out looks could not be overcome within a -few days. Nevertheless, a gate was opened for communications interchange in the future. There was even a problem within each specialty, and as is rather common, quite diverse views have been expressed. This, of course, is quite normal in the progress of science.

The Scientist's Guide to Cardiac Metabolism

Author : Michael Schwarzer
Publisher : Academic Press
ISBN 13 : 0128026146
Total Pages : 241 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Scientist's Guide to Cardiac Metabolism by : Michael Schwarzer

Download or read book The Scientist's Guide to Cardiac Metabolism written by Michael Schwarzer and published by Academic Press. This book was released on 2015-11-04 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. - Provides a quick and comprehensive introduction into cardiac metabolism - Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs - Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function - Includes historical perspectives that reference important investigators that have contributed to the development of the field

Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

Author : Thomas Pulinilkunnil
Publisher : Frontiers Media SA
ISBN 13 : 2889459381
Total Pages : 89 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease by : Thomas Pulinilkunnil

Download or read book Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease written by Thomas Pulinilkunnil and published by Frontiers Media SA. This book was released on 2019-08-08 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Inotropic Stimulation and Myocardial Energetics

Author : H. Just
Publisher : Springer Science & Business Media
ISBN 13 : 3662079089
Total Pages : 429 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Inotropic Stimulation and Myocardial Energetics by : H. Just

Download or read book Inotropic Stimulation and Myocardial Energetics written by H. Just and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inotropic stimulation of the myocardium, as well as vasodilation and diuresis as essential principles in the treatment of congestive heart failure have recently met with considerable criticism and reevaluation. It is generally agreed that unloading of the heart, either through vasodilation and/or diuresis, improves the working conditions of the dilated, failing heart. It reduces myocar dial oxygen consumption through reduction of chamber radius and, thereby, wall tension as the major determinants of myocardial oxygen consumption. Inotropic stimulation, quite in contrast, does not conserve oxygen. It rather consumes energy and that may be disadvantageous in situations of compromised oxygen supply and energy metabolism of the working myocardium. However, under conditions of suf ficient oxygen supply and metabolic support inotropic stimulation may bring about in creased pumping and subsequent improvement of myocardial failure. In recent years it could convincingly be demonstrated that vasodilation leads to symp tomatic improvement of congestive heart failure, improvement of exercise tolerance, and it prolongs life - especially in the case of ACE-inhibitors and the combination of hydra lazine with long-acting nitrates. Quite in contrast, equally beneficial effects could not be demonstrated for inotropic agents in congestive heart failure. Only for the cardiac glyco sides has it been shown that beneficial effects can be achieved, especially if atrial fibril lation with absolute arrhythmia is present. The influence of the cardiac glycosides on the latter represents an effect which is independent of the inotropic action.

Cardiac Energetics in the Isolated Heart by NMR Spectroscopy and Mathematical Modeling

Author : Ming Lu
Publisher :
ISBN 13 :
Total Pages : 125 pages
Book Rating : 4.:/5 (635 download)

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Book Synopsis Cardiac Energetics in the Isolated Heart by NMR Spectroscopy and Mathematical Modeling by : Ming Lu

Download or read book Cardiac Energetics in the Isolated Heart by NMR Spectroscopy and Mathematical Modeling written by Ming Lu and published by . This book was released on 2010 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiac Energetics

Author : Helen Kiriazis
Publisher :
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.:/5 (225 download)

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Book Synopsis Cardiac Energetics by : Helen Kiriazis

Download or read book Cardiac Energetics written by Helen Kiriazis and published by . This book was released on 1997 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Heart's Code

Author : Paul P. Pearsall
Publisher : Harmony
ISBN 13 : 0767999428
Total Pages : 304 pages
Book Rating : 4.7/5 (679 download)

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Book Synopsis The Heart's Code by : Paul P. Pearsall

Download or read book The Heart's Code written by Paul P. Pearsall and published by Harmony. This book was released on 1999-03-10 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating synthesis of ancient wisdom, modern medicine, scientific research, and personal experiences that proves that the human heart, not the brain, holds the secrets that link body, mind, and spirit. You know that the heart loves and feels, but did you know that the heart also thinks, remembers, communicates with other hearts, helps regulate immunity, and contains stored information that continually pulses through your body? In The Heart's Code, Dr. Paul Pearsall explains the theory and science behind energy cardiology, the emerging field that is uncovering one of the most significant medical, social, and spiritual discoveries of our time: The heart is more than just a pump; it conducts the cellular symphony that is the very essence of our being. Full of amazing anecdotes and data, The Heart's Code presents the latest research on cellular memory and the power of the heart's energy and explores what these breakthroughs mean about how we should live our lives. By unlocking the heart's code we can discover new ways of understanding human healing and consciousness and create a new model for living that leads to better health, happiness, and self-knowledge.

Insight Into the Heart

Author : Samuel Sideman
Publisher :
ISBN 13 :
Total Pages : 69 pages
Book Rating : 4.:/5 (169 download)

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Book Synopsis Insight Into the Heart by : Samuel Sideman

Download or read book Insight Into the Heart written by Samuel Sideman and published by . This book was released on 2005 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inotropic Stimulation and Myocardial Energetics

Author : H. Just
Publisher :
ISBN 13 : 9783662079096
Total Pages : 284 pages
Book Rating : 4.0/5 (79 download)

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Book Synopsis Inotropic Stimulation and Myocardial Energetics by : H. Just

Download or read book Inotropic Stimulation and Myocardial Energetics written by H. Just and published by . This book was released on 2014-01-15 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heart Perfusion, Energetics, and Ischemia

Author : Leopold Dintenfass
Publisher : Springer
ISBN 13 : 9781475703948
Total Pages : 720 pages
Book Rating : 4.7/5 (39 download)

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Book Synopsis Heart Perfusion, Energetics, and Ischemia by : Leopold Dintenfass

Download or read book Heart Perfusion, Energetics, and Ischemia written by Leopold Dintenfass and published by Springer. This book was released on 2014-01-15 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comparative Analysis of Cardiac Energetics in Isolated Hearts Supported by Pulsatile Or Rotary Blood Pumps - Imlications for Cardiac Recovery?

Download Comparative Analysis of Cardiac Energetics in Isolated Hearts Supported by Pulsatile Or Rotary Blood Pumps - Imlications for Cardiac Recovery? PDF Online Free

Author : Benedikt Locher
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (114 download)

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Book Synopsis Comparative Analysis of Cardiac Energetics in Isolated Hearts Supported by Pulsatile Or Rotary Blood Pumps - Imlications for Cardiac Recovery? by : Benedikt Locher

Download or read book Comparative Analysis of Cardiac Energetics in Isolated Hearts Supported by Pulsatile Or Rotary Blood Pumps - Imlications for Cardiac Recovery? written by Benedikt Locher and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: