Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Carbohydrate Mimics
Download Carbohydrate Mimics full books in PDF, epub, and Kindle. Read online Carbohydrate Mimics ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Carbohydrate Mimics by : Yves Chapleur
Download or read book Carbohydrate Mimics written by Yves Chapleur and published by Wiley-VCH. This book was released on 1998-09-10 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Mimics Concepts and Methods Edited by Yves Chapleur Apart from the various functions of carbohydrates in natural processes they are important building blocks for drugs, especially antibiotics. In addition, carbohydrates are considered as important structures in the immunological recognition process of the antigen-antibody reaction. The modification of the structure and thereby the chemistry of substrates is a common procedure in nature. This naturally occurring process is reflected in the concept of molecular mimicry, which has become a useful approach in drug discovery. The search for carbohydrate analogues that exhibit better binding activity, biological activity, and stability began with the synthesis of azasugars. A lot of structural modifications around the anomeric center of carbohydrates has been achieved over the last decade, and these are summarized in terms of the different chemical and biological aspects of carbohydrate mimics in one part of this book. In addition to the well established fields of C-glycosides, azasugars and carbasugars the other part of the book focusses on outstanding achievements in carbohydrate mimic research. Everybody who is active in carbohydrate research or is interested in moving into this exciting field will benefit from this up-to-date source of informations. The leading experts in this field describe their scientific approaches to real interdisciplinary puzzles. This book should be an inspiration to scientists in organic, medicinal chemistry, biochemistry, and biology.
Author :Institute of Medicine (U.S.). Committee on Military Nutrition Research Publisher :National Academies ISBN 13 : Total Pages :260 pages Book Rating :4.1/5 (398 download)
Book Synopsis Fluid Replacement and Heat Stress by : Institute of Medicine (U.S.). Committee on Military Nutrition Research
Download or read book Fluid Replacement and Heat Stress written by Institute of Medicine (U.S.). Committee on Military Nutrition Research and published by National Academies. This book was released on 1994 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Carbohydrate Chemistry by : Amelia Pilar Rauter
Download or read book Carbohydrate Chemistry written by Amelia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2011 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Book Synopsis Carbohydrate-based Drug Discovery by : Chi-Huey Wong
Download or read book Carbohydrate-based Drug Discovery written by Chi-Huey Wong and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: > Chemical Synthesis of Carbohydrates > Carbohydrate Biosynthesis and Metabolism > Carbohydrate Analysis > Cellular Functions of Carbohydrates > Development of Carbohydrate-based Drugs A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists.
Book Synopsis Glycomimetics by : Brian Alvin Johns
Download or read book Glycomimetics written by Brian Alvin Johns and published by . This book was released on 1997 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carbohydrates written by Robert V. Stick and published by Academic Press. This book was released on 2001-03-13 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the field of carbohydrates from theoretical, mechanistic and practical points of view, topics covered include: synthesis and protecting groups; reactions of monosaccharides; synthesis of the glycosidic linkage; synthesis of oligosaccharides; polysaccharides; and glycoconjugates.
Book Synopsis Synthesis and Characterization of Carbohydrate Mimics by : Lucas K. Beagle
Download or read book Synthesis and Characterization of Carbohydrate Mimics written by Lucas K. Beagle and published by . This book was released on 2008 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synthesis of N-acetyl-D-fucosamine and N-((2R,3R,4R)-2,4-dihydroxy-6-methylene-5-oxo-tetrahydro-2H-pyran-3-yl)acetamide will be pursued from the inexpensive starting material N-acetyl-D-glucosamine. These carbohydrates are mimics of intermediates used by Staphylococcus aureus in the construction of its protective capsular polysaccharide, which allows the bacteria to evade both the host immune system and antibiotics in current use. Synthesis of these molecules allows for carbohydrate mimics to be developed which can be used as targeted antibiotics needed for use against antibiotic-resistant Staphylococcus aureus strains. Characterization by nuclear magnetic resonance spectroscopy will allow determination of structural conformation, of structures' dependence on solvent while in solution, and presence of the desired product. These studies will be carried out to be compared with other structural determination techniques in wide use today. Knowledge of the solution state structure of a molecule is necessary to understand the possible interactions in biological systems which must be understood in pharmaceutical development. Recent developments in NMR techniques allow for multi-dimensional spectra which can relate interconnected atoms in a molecule to provide information on the relative spatial orientation of atoms within a molecule.
Book Synopsis Carbohydrate Recognition by : Binghe Wang
Download or read book Carbohydrate Recognition written by Binghe Wang and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Book Synopsis Carbohydrate Chemistry by : Amelia Pilar Rauter
Download or read book Carbohydrate Chemistry written by Amelia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2012-08-31 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, glycochemistry and glycobiology have been combined to demonstrate the contribution of organic chemistry, modern analytics, biological and biochemical expertise to the increasingly important field of glycomincs. A polysaccharide immunomodulator with therapeutic implications, carbohydrate vaccines, new findings emphasizing the influence of carbohydrate decoration on the regulation of inflammatory response and new therapeutic approaches in the treatment of acute and chronic inflammatory diseases, recent approachesin the treatment of acute and chronic inflammatory diseases, recent progress on glycoengineering based on a glycosylation, and key aspects of the glycosylation changes associated with bladder cancer are amongst the subjects presented in this volume. The contribution of glycochemistry to innovation in glycosciences is shown with chapters covering highly functionalized exo-glycals for the generation of molecular diversity in a chemoselective manner, imino sugar glycosidase inhibitors, carbasugars, multivalent glycoconjugates, including glycodendrimers, glyconanotubes, and glyconanoparticles, and their uses in medicinal chemistry, as well as artificial saccharide-based and saccharide functionalized gene delivery systems. Siderphores based on monosaccharides (which have proven effective for Gram-negative bacteria and mycobacteria), and the so-called smart materials, (which can modulate and control cell behaviour), complete the volume. Volume 38 of Carbohydrate Chemistry - Chemical and Biological Apporaches contains contributions ranging from glycochemistry to glycobiology. This collection demonstrates in a meaningful way how the interdisciplinary approach of an international glyconetwork can advance the field of carbohydrate research in Europe and worldwide.
Book Synopsis Carbohydrates as Drugs by : Peter H. Seeberger
Download or read book Carbohydrates as Drugs written by Peter H. Seeberger and published by Springer. This book was released on 2014-11-14 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Book Synopsis Carbohydrate Recognition by : Binghe Wang
Download or read book Carbohydrate Recognition written by Binghe Wang and published by John Wiley & Sons. This book was released on 2011-09-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Book Synopsis Carbohydrate Chemistry by : Yves Queneau
Download or read book Carbohydrate Chemistry written by Yves Queneau and published by Royal Society of Chemistry. This book was released on 2014 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 40 of Carbohydrate Chemistry: Chemical and Biological Approaches demonstrates the importance of the glycosciences for innovation and societal progress. Carbohydrates are molecules with essential roles in biology and also serve as renewable resources for the generation of new chemicals and materials. Honouring Professor André Lubineau's memory, this volume resembles a special collection of contributions in the fields of green and low-carbon chemistry, innovative synthetic methodology and design of carbohydrate architectures for medicinal and biological chemistry. Green methodology is illustrated by accounts on the industrial development of water-promoted reactions (C-glycosylation, cycloadditions) and the design of green processes and synthons towards sugar-based surfactants and materials. The especially challenging transformations at the anomeric center are presented in several contributions on glycosylation methodologies using iron or gold catalysis, electrochemical or enzymatic (thio)glycosylation, exo-glycal chemistry and bioengineering of carbohydrate synthases. Then, synthesis and structure of multivalent and supramolecular oligosaccharide architectures are discussed and related to their physical properties and application potential, e.g. for deepening our understanding of biological processes, such as enzymatic pathways or bacterial adhesion, and design of antibacterial, antifungal and innovative anticancer vaccines or drugs.
Book Synopsis Synthesis of C-glycosides as Carbohydrate Mimics by : Travis D. Weaver
Download or read book Synthesis of C-glycosides as Carbohydrate Mimics written by Travis D. Weaver and published by . This book was released on 2005 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Modern Synthetic Methods in Carbohydrate Chemistry by : Daniel B. Werz
Download or read book Modern Synthetic Methods in Carbohydrate Chemistry written by Daniel B. Werz and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of glycochemistry and glycoscience are rich and varied and where much can be learned from Nature. As Nature is not always able to produce carbohydrates in quantities useful for not only in research but also as therapeutic agents, new ways need to be found to optimize the yield. This book presents an overview of the latest developments in the field of carbohydrates, ranging from de-novo approaches via cyclodextrin chemistry to the synthesis of such highly complex glycoconjugates as glycosphingolipids and GPI anchors. The main emphasis remains on the synthetic aspects making the book an excellent source of information for those already involved in carbohydrate chemistry, as well as for those organic chemists who are beginners in this field. Equally of interest to synthetic chemists, as well as medicinal chemists and biochemists.
Book Synopsis Bioactive Conformation II by : Thomas Peters
Download or read book Bioactive Conformation II written by Thomas Peters and published by Springer. This book was released on 2009-11-04 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The volume is still valid and useful after five or ten years. More information, as well as the electronic version of the whole content, is available at: springerlink.com.
Book Synopsis Carbohydrate-spiro-heterocycles by : László Somsák
Download or read book Carbohydrate-spiro-heterocycles written by László Somsák and published by Springer Nature. This book was released on 2019-10-26 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is devoted to compounds in which the spiro centre is part of a pyranoid or furanoid or an iminosugar ring. The chapters contributed deal with methodological peculiarities of syntheses of natural and artificial sugar derived spirocycles as well as their biological applications and other utilities including marketed drugs. Carbohydrates are ubiquitous molecules in nature and participate in a vast number of biological interactions. Especially their conjugates with practically all kinds of primary and secondary metabolic small molecules (and also biomacromolecules) representing valuable tools for glycobiology research and also lead compounds for drug discovery. While monosaccharides per se appear as heterocycles, their natural conjugates frequently exhibit spiro(hetero)cyclic derivatives, in many cases of high therapeutical relevance. As a consequence, the field of carbohydrate-spiro-heterocycles attracts intense interest from both chemical and biomedical aspects therefore this volume will be of interest for synthetic and medicinal chemists and (glyco)biologists, as well as researchers involved in various biomedical fields.
Book Synopsis Advances in Carbohydrate Chemistry and Biochemistry by :
Download or read book Advances in Carbohydrate Chemistry and Biochemistry written by and published by Academic Press. This book was released on 2012-12-05 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - Features contributions from leading authorities and industry experts - Informs and updates on all the latest developments in the field
