Camptothecin And Camptothecin Producing Plants

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Camptothecin and Camptothecin Producing Plants

Author : T. Pullaiah
Publisher : Academic Press
ISBN 13 : 0128209275
Total Pages : 369 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Camptothecin and Camptothecin Producing Plants by : T. Pullaiah

Download or read book Camptothecin and Camptothecin Producing Plants written by T. Pullaiah and published by Academic Press. This book was released on 2020-06-18 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment. Provides information on camptothecin producing plants and their anticancer properties for the development of new treatments Discusses new applications of camptothecin based on recent biotechnology advancements Presents comprehensive information on the pharmacology of camptothecin for leveraging new anticancer drugs developments

50 Years of Phytochemistry Research

Author : David R. Gang
Publisher : Springer Science & Business Media
ISBN 13 : 3319005812
Total Pages : 159 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis 50 Years of Phytochemistry Research by : David R. Gang

Download or read book 50 Years of Phytochemistry Research written by David R. Gang and published by Springer Science & Business Media. This book was released on 2013-12-03 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 43rd volume of RAP includes a total of seven articles based on talks presented at the 50th Anniversary meeting of the PSNA, which was held at the Fairmont Orchid, in Waikoloa, Hawai’i, USA. These seven Perspectives give a very good picture of the breadth of plant (bio)chemistry research in North America, which is also indicative of the state of the field worldwide. Each of these articles describes the integration of several different approaches to ask and then answer interesting questions regarding the function of interesting plant metabolites, either in the plant itself or in interactions with the environment (natural setting or human health application). Two Perspectives outline very clearly the power of approaching biological questions from a modern, “omics” or systems biology approach. Beale and Ward outline how metabolomics approaches can be brought to bear on plant biosynthetic questions and quickly lead to important advances in our understanding or how plants produce important metabolites. Zandkarimi et al. outline the integration of ion mobility spectrometry into mass spectrometry-based metabolomics investigations and show clearly how powerful those two spectrometric technologies can be when used together.

Exploring Plant Cells for the Production of Compounds of Interest

Author : Sonia Malik
Publisher : Springer Nature
ISBN 13 : 303058271X
Total Pages : 353 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Exploring Plant Cells for the Production of Compounds of Interest by : Sonia Malik

Download or read book Exploring Plant Cells for the Production of Compounds of Interest written by Sonia Malik and published by Springer Nature. This book was released on 2021-04-10 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural compounds obtained from plants represent a tremendous global market due to their use as food additives, cosmetics, in agriculture and in pharmaceuticals. This book provides up-to-date information on various strategies and methods for producing compounds of interest. Leading researchers discuss the latest advances in environmentally friendly natural compound production from plants, making the book a valuable resource for biotechnologists, pharmacists, food technologists and researchers working in the medical and healthcare industries.

Chemistry of Plant Natural Products

Author : Sunil Kumar Talapatra
Publisher : Springer
ISBN 13 : 3642454100
Total Pages : 1180 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Chemistry of Plant Natural Products by : Sunil Kumar Talapatra

Download or read book Chemistry of Plant Natural Products written by Sunil Kumar Talapatra and published by Springer. This book was released on 2015-03-05 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.

Anticancer plants: Properties and Application

Author : Mohd Sayeed Akhtar
Publisher : Springer
ISBN 13 : 981108548X
Total Pages : 582 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Anticancer plants: Properties and Application by : Mohd Sayeed Akhtar

Download or read book Anticancer plants: Properties and Application written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-06-29 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.

Natural Small Molecule Drugs from Plants

Author : Guan-Hua Du
Publisher : Springer
ISBN 13 : 9811080224
Total Pages : 741 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Natural Small Molecule Drugs from Plants by : Guan-Hua Du

Download or read book Natural Small Molecule Drugs from Plants written by Guan-Hua Du and published by Springer. This book was released on 2018-11-19 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses 120 types of natural, small-molecule drugs derived from plants. They are grouped into 7 parts according their clinical uses, such as drugs for cardiovascular diseases, for metabolic diseases, for neuropsychiatric diseases, for immune-mediated inflammatory diseases, anti-tumor drugs, and drugs for parasites and bacterial infection. Each chapter systematically summarizes one drug, including its physicochemical properties, sources, pharmacological effects and clinical applications. To help readers understand the drug better, the research and pharmacological activity for each drug is also described, which serves as a salutary lesson for future drug development. Written by frontline researchers, teachers and clinicians working in field of pharmacy and pharmacology it provides an overview of natural, small-molecule drugs derived from plants for researchers in the field.

Camptotheca Acuminata Decaisne (Nyssaceae) Source of Camptothecin

Author : Robert E. Perdue
Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis Camptotheca Acuminata Decaisne (Nyssaceae) Source of Camptothecin by : Robert E. Perdue

Download or read book Camptotheca Acuminata Decaisne (Nyssaceae) Source of Camptothecin written by Robert E. Perdue and published by . This book was released on 1970 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anticancer Agents from Natural Products

Author : Gordon M. Cragg
Publisher : CRC Press
ISBN 13 : 1420039652
Total Pages : 610 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Anticancer Agents from Natural Products by : Gordon M. Cragg

Download or read book Anticancer Agents from Natural Products written by Gordon M. Cragg and published by CRC Press. This book was released on 2005-06-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen

Cytotoxicity

Author : Erman Salih Istifli
Publisher : BoD – Books on Demand
ISBN 13 : 1789847540
Total Pages : 120 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Cytotoxicity by : Erman Salih Istifli

Download or read book Cytotoxicity written by Erman Salih Istifli and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compensating for cytotoxicity in the multicellular organism by a certain level of cellular proliferation is the primary aim of homeostasis. In addition, the loss of cellular proliferation control (tumorigenesis) is at least as important as cytotoxicity, however, it is a contrasting trauma. With the disruption of the delicate balance between cytotoxicity and proliferation, confrontation with cancer can inevitably occur. This book presents important information pertaining to the molecular control of the mechanisms of cytotoxicity and cellular proliferation as they relate to cancer. It is designed for students and researchers studying cytotoxicity and its control.

Recent Trends in Medicinal Plants Research

Author :
Publisher : Academic Press
ISBN 13 : 0123947995
Total Pages : 468 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Recent Trends in Medicinal Plants Research by :

Download or read book Recent Trends in Medicinal Plants Research written by and published by Academic Press. This book was released on 2012-11-13 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants and other living organisms have great potential to treat human disease. There are two distinct types of biomedical research that seek to develop this potential. One type of research explores the value of medicinal plants as traditionally used and studies of these plants have the potential to determine which plants are most potent, optimize dosages and dose forms, and identify safety risks. Another type of research uses bioassays to identify single molecules from plants that have interesting bioactivities in isolation and might be useful lead compounds for the development of pharmaceutical drugs. This new volume of Advances in Botanical Research covers the recent trends in Medicinal Plants Research over 11 chapters. Topics that are covered include Development of Drugs from Plants – Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy. Covers the recent trends in medicinal plants research over 11 chapters Topics that are covered include Development of Drugs from Plants – Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy

Secondary Metabolites

Author : Ramasamy Vijayakumar
Publisher : BoD – Books on Demand
ISBN 13 : 1789236428
Total Pages : 149 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Secondary Metabolites by : Ramasamy Vijayakumar

Download or read book Secondary Metabolites written by Ramasamy Vijayakumar and published by BoD – Books on Demand. This book was released on 2018-09-05 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and regulation of secondary metabolite production. This book provides a comprehensive account on the secondary metabolites of microorganisms, plants, and the production of secondary metabolites through biotechnological approach like the plant tissue culture method. The regulatory mechanisms of secondary metabolite production in plants and the pharmaceutical and other applications of various secondary metabolites are also highlighted. This book is considered as necessary reading for microbiologists, biotechnologists, biochemists, pharmacologists, and botanists who are doing research in secondary metabolites. It should also be useful to MSc students, MPhil and PhD scholars, scientists, and faculty members of various science disciplines.

New Light on Alkaloid Biosynthesis and Future Prospects

Author :
Publisher : Academic Press
ISBN 13 : 0080994113
Total Pages : 400 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis New Light on Alkaloid Biosynthesis and Future Prospects by :

Download or read book New Light on Alkaloid Biosynthesis and Future Prospects written by and published by Academic Press. This book was released on 2013-07-27 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 68th volume, the series features varied reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on a new light on alkaloid biosynthesis and future prospects. In-depth and up-to-date reviews on a wide range of topics in plant sciences Features varied reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology Features reviews on biosynthesis of alkaloids in plants

The Story of Taxol

Author : Jordan Goodman
Publisher : Cambridge University Press
ISBN 13 : 9780521561235
Total Pages : 302 pages
Book Rating : 4.5/5 (612 download)

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Book Synopsis The Story of Taxol by : Jordan Goodman

Download or read book The Story of Taxol written by Jordan Goodman and published by Cambridge University Press. This book was released on 2001-03-05 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taxol is arguably the most celebrated, talked-about and controversial natural product in recent years. It is celebrated because of its efficacy as an anti-cancer drug and because its discovery has provided powerful support for policies concerned with biodiversity; talked about because in the late 1980s and early 1990s the American public was bombarded with news reports and special programmes about the molecule and its host, the Pacific yew; and controversial because during the early 1990s the drug and the tree became embroiled in a number of very sensitive political issues with wide implications for the conduct of public policy. The Story of Taxol tells this story.

Medicinal Chemistry of Anticancer Drugs

Author : Carmen Avendaño
Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature

Ethnopharmacology of Medicinal Plants

Author : Christophe Wiart
Publisher : Springer Science & Business Media
ISBN 13 : 1597451606
Total Pages : 228 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Ethnopharmacology of Medicinal Plants by : Christophe Wiart

Download or read book Ethnopharmacology of Medicinal Plants written by Christophe Wiart and published by Springer Science & Business Media. This book was released on 2007-11-04 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1860, Oliver Wendell Holmes pointedly expressed himself to the Massachusetts Medical Society: “I firmly believe that if the whole Material Medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind, and all the worst for the fishes.” Should one think the same about the current approach in drug discovery from plants? Probably yes. Despite the spending of billions of US dollars, and three decades of efforts, high-throughput screenings have only allowed the discovery of a couple of drugs. One could have reasonably expected the discovery of an arsenal of drugs from the millions of plant extracts randomly tested, but “hits” can be inactive in vitro or too toxic, some molecules need to be metabolized first to be active, and false-positive and false-negative results are common. The bitter truth is that the robotic approach in discovering drugs from plants has proven, to date, its inability to excavate the hundreds of molecules that will contribute to the health progress of Man. However, one can reasonably see that the last patches of primary rainforest on earth hold still hundreds of spectacularly active drugs that await discovery.

Biological Activities of Alkaloids

Author : Sabino Aurelio Bufo
Publisher : MDPI
ISBN 13 : 3039289276
Total Pages : 270 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Biological Activities of Alkaloids by : Sabino Aurelio Bufo

Download or read book Biological Activities of Alkaloids written by Sabino Aurelio Bufo and published by MDPI. This book was released on 2020-05-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.

Plant Cell and Tissue Differentiation and Secondary Metabolites

Author : Kishan Gopal Ramawat
Publisher : Springer
ISBN 13 : 9783030301842
Total Pages : 0 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Plant Cell and Tissue Differentiation and Secondary Metabolites by : Kishan Gopal Ramawat

Download or read book Plant Cell and Tissue Differentiation and Secondary Metabolites written by Kishan Gopal Ramawat and published by Springer. This book was released on 2020-12-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides a comprehensive review of cell and tissue differentiation and its role in the formation of specific secondary metabolites. Divided into five sections, this book covers the main cellular processes involved in the biosynthesis of secondary metabolites. Chapters from expert contributors offer specific case studies of cell and tissue differentiation, examines secondary metabolites in shoot and root cultures, and present new scientific insights and original technologies with applications in medicinal plants and in plant biotechnology. Students, scholars and researchers with an interest in the fields of botany, agriculture, pharmacy, biotechnology and phytochemistry will find this book an important account. This book will also engage professionals working in plant-based industry.