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Author : Albrecht Fleckenstein
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.3/5 (91 download)
Download or read book Calcium Antagonism in Heart and Smooth Muscle written by Albrecht Fleckenstein and published by John Wiley & Sons. This book was released on 1983 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fleckenstein
Publisher :
ISBN 13 : 9780471845485
Total Pages : pages
Book Rating : 4.8/5 (454 download)
Download or read book Calcium Antagonism in Heart and Smooth Muscle written by Fleckenstein and published by . This book was released on 1997-05-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : International Society for Heart Research. American Section. Meeting
Publisher : Springer
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)
Download or read book Calcium Antagonists written by International Society for Heart Research. American Section. Meeting and published by Springer. This book was released on 1984-05-31 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Proceedings of the Meeting of the American Section of the International Society for Heart Research (ISHR) at Hilton Head, South Carolina, September 21-24, 1983
Author : Nicholas Sperelakis
Publisher : Springer
ISBN 13 : 9781461338123
Total Pages : 352 pages
Book Rating : 4.3/5 (381 download)
Download or read book Calcium Antagonists written by Nicholas Sperelakis and published by Springer. This book was released on 2011-10-12 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Proceedings of the Meeting of the American Section of the International Society for Heart Research (ISHR) at Hilton Head, South Carolina, September 21-24, 1983
Author : Winifred G. Nayler
Publisher : Springer
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.3/5 (91 download)
Download or read book Second Generation of Calcium Antagonists written by Winifred G. Nayler and published by Springer. This book was released on 1991 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. Fleckenstein
Publisher : Springer Science & Business Media
ISBN 13 : 3642704999
Total Pages : 520 pages
Book Rating : 4.6/5 (427 download)
Download or read book Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists written by A. Fleckenstein and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Held at Boppard, Germany, October 3-6, 1984
Author : Lionel H. Opie
Publisher : Springer Science & Business Media
ISBN 13 : 1461308631
Total Pages : 315 pages
Book Rating : 4.4/5 (613 download)
Download or read book Clinical Use of Calcium Channel Antagonist Drugs written by Lionel H. Opie and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium antagonists are now regarded as the most important advance in cardiac drug therapy since the advent of beta-adrenergic blocking agents. Acting ba sically as vasodilators-though with many other com plex mechanisms especially in the case of the anti arrhythmic calcium antagonists, these agents have grown in importance to become among the therapeutic agents of first choice for angina pectoris and hyper tension. The major aim of the present book is to present the clinician with the information needed for the practical use of calcium antagonists. What do all the numerous and often conflicting trials say? Do these agents really work? If so, which agent and in what dose? How do the three front runners, verapamil, nifedipine and diltia zem compare in the efficacy and side-effects with each other? How do the new second generation agents, now entering the North American market, slot in and com pare with the three first-liners? When the gloss is taken away from the advertisements, what is really left? The strong clinical bias of the present book should be complimented by further reading of books slanted towards fundamentals. One of the most important and recent of these is that by Dr Winifred Nayler (Calcium Antagonists, Academic Press, 1988). That book should be basic for essential background knowledge in the area of calcium antagonists. The important basic contribu tions of Fleckenstein deserve emphasis.
Author : A. K. Grover
Publisher : Springer Science & Business Media
ISBN 13 : 1461251729
Total Pages : 498 pages
Book Rating : 4.4/5 (612 download)
Download or read book Calcium and Contractility written by A. K. Grover and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: In organizing the present volume, we had two intentions. The first was to present the best current understanding of the mechanisms of calcium mobilization during excitation contraction coupling of smooth muscle at a level suited to the needs of professionals interested in smooth muscle pharmacology and pathophysiology, while remaining appreciable by graduate and medical students. The second intention was to provide in sight into present-day controversies, as well as the latest ad vances achieved by researchers in this field. Thus, we have thor oughly discussed both the techniques and the concepts derived from their application. An attempt has also been made here to answer a number of profoundly important questions: What are the mechanisms and agents responsible for the control of contractility? What are the accompanying changes in the state of intracellular calcium ions and the mechanisms responsible for them? How does the regula tion of contractility occur directly at the level of the actomyosin activity? What role do gap junctions play in cell-to-cell coupling? What are the roles of cholinergic, adrenergic, peptidergic, and nonadrenergic noncholinergic interactions in calcium mobiliza tion in smooth muscle? What changes occur in hypertension? The impact of these recent techniques on future research is also reflected upon.
Author : T. Godfraind
Publisher : Springer Science & Business Media
ISBN 13 : 940111725X
Total Pages : 382 pages
Book Rating : 4.4/5 (11 download)
Download or read book Calcium Antagonists written by T. Godfraind and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the importance of calcium (Ca2+) in the maintenance of cardiac contractility was recognized as early as 1880, the critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades. As the complexity of the pharmacological actions of the Ca2+ channel inhibitors grows, there is a continued need to further clarify the inhibitors, both chemically and functionally. This volume provides an update of the field based on the work presented at the 5th International Symposium on Calcium Antagonists: Pharmacology and Clinical Research. It reviews the current state of the growing area of molecular biology of Ca2+ channels. In the cardiovascular area, in addition to the well-established clinical uses of Ca2+ channel inhibitors, exciting new work pointing to an application in atherosclerosis is described. The book also includes important uses of Ca2+ antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance.
Author : Winifred G. Nayler
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)
Download or read book Calcium Antagonists written by Winifred G. Nayler and published by . This book was released on 1988 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Murray Epstein
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)
Download or read book Calcium Antagonists in Clinical Medicine written by Murray Epstein and published by . This book was released on 1992 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised and expanded new edition presents the current state of knowledge of the diverse applications of calcium antagonists and makes recommendations about their appropriate use. New sections have been added on Clinical Pharmacology and Metabolic Effects. Sixteen new chapters have been added on such topics as Pharmacogenetics of Hypertension: Using Gene Markers to Infer Pathogenesis and Guide Therapy, New Pharmacologic Directions for Calcium Channel Blockers, Calcium Channel Blocker Use in End-Stage Renal Disease: Pharmacokinetics and Pharmacodynamics, and many others.
Author : Paul R. Lichtlen
Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)
Download or read book Recent Aspects in Calcium Antagonism written by Paul R. Lichtlen and published by . This book was released on 1985 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kazuo Yamada
Publisher :
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.3/5 (91 download)
Download or read book Recent Advances in Calcium Channels and Calcium Antagonists written by Kazuo Yamada and published by . This book was released on 1990 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kyuzo Aoki
Publisher : Springer
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.3/5 (91 download)
Download or read book Essential Hypertension written by Kyuzo Aoki and published by Springer. This book was released on 1986 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Théophile Godfraind
Publisher :
ISBN 13 :
Total Pages : 420 pages
Book Rating : 4.:/5 (45 download)
Download or read book Calcium Modulators written by Théophile Godfraind and published by . This book was released on 1982 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Weiss
Publisher : Oxford University Press
ISBN 13 : 9780195206920
Total Pages : 252 pages
Book Rating : 4.2/5 (69 download)
Download or read book New Perspectives on Calcium Antagonists written by Weiss and published by Oxford University Press. This book was released on 1988 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines the varied actions and effects of calcium antagonists. It shows how the differences in cellular and molecular patterns of calcium mobilization in the heart, in various types of smooth muscle, in secretory systems, and in other tissues provide a scientific basis for development of an equally diverse family of calcium agents of increasing specificity and efficacy. This is an ideal reference for clinicians and scientists interested in this new class of therapeutic agents.
Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
