Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Breast Cancer And Its Precursor Lesions
Download Breast Cancer And Its Precursor Lesions full books in PDF, epub, and Kindle. Read online Breast Cancer And Its Precursor Lesions ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Breast Cancer and its Precursor Lesions by : Patricia A. Thomas
Download or read book Breast Cancer and its Precursor Lesions written by Patricia A. Thomas and published by Springer Science & Business Media. This book was released on 2010-10-20 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rather than an exhaustive review of all the pathologic conditions of the female breast, Breast Cancer and its Precursor Lesions focuses on the current knowledge, understanding and issues related to breast cancer and its benign lesions that are associated with an increased risk for the subsequent development of cancer. This book targets the language, diagnostic terms and critical communication that must take place between primary care physicians, breast surgeons, oncologists, and general surgical pathologists interested in the pathologist’s perspective on these important diseases. The volume also reviews the current terminology and how to read or write meaningful pathology reports on these entities, the foils and nuances of the pathology and implications for management, and up to date issues in genomics and proteomics of these conditions. The text is succinct, fully informative, and written in “plain language”. All chapters are presented in a uniform fashion, and supplemented by high-quality illustrations and tables. Breast Cancer and its Precursor Lesions will be of great value to pathologists as well as primary care physicians, breast surgeons, and oncologists for understanding breast pathology and its implications for management.
Book Synopsis Pathology of Female Cancers by : Takuya Moriya
Download or read book Pathology of Female Cancers written by Takuya Moriya and published by Springer. This book was released on 2018-07-31 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on precursor lesions, borderline lesions, and early carcinomas of female-specific organs from the standpoint of pathology. In 2012, WHO Classification of Tumours of the Breast was revised and subsequently, in 2014, the WHO Classification of Tumours of Female Reproductive Organs was revised. In these latest versions, several new concepts are addressed that were not described in the previous editions, and many of them are related to the awareness of the specific pathogenesis of tumors in female patients. Although some of these issues are still controversial, several paradigm shifts should be understood by medical scientists. Thus researchers, diagnostic pathologists, and clinicians must share current information about what is taking place in the field and what the next issue to resolve is. This volume greatly broadens the reader’s understanding of the new concepts and paradigm shifts, as it includes information on how to diagnose and make differential diagnoses on a practical basis and also provides a thorough explanation of the molecular–clinicopathologic basis of the new concepts. The book thus benefits gynecologists, breast surgeons, gynecologic–medical oncologists, and cytotechnologists.
Book Synopsis Breast Cancer Resource for Research and Banking, with Emphasis on Early Tumors and Precursor Lesions by :
Download or read book Breast Cancer Resource for Research and Banking, with Emphasis on Early Tumors and Precursor Lesions written by and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Breast Cancer Resource for Research and Banking has accrued breast cells or tissues from 1342 patients during the three year grant period to date. The emphasis of this project is on the collection of microscopic at risk and precursor lesions as imprints/scrapes. These constitute over half of our specimens. However, most investigators who have requested samples have requested frozen pieces of tumor tissue paired with normal tissue from the same patient, ie. their interest has been in invasive carcinomas and not in precursor lesions. We have also begun to fill requests for microdissection, which is emerging as a favored method for studying microscopic lesions.
Book Synopsis Atypical Breast Proliferative Lesions and Benign Breast Disease by : Farin Amersi
Download or read book Atypical Breast Proliferative Lesions and Benign Breast Disease written by Farin Amersi and published by Springer. This book was released on 2018-09-27 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of atypical breast lesions continues to evolve. There is considerable controversy as to whether these entities represent risk factors for future breast cancer or whether they are instead precursor lesions. A better understanding of the prognostic and therapeutic implications of each of these lesions is important for assessing subsequent breast cancer risk. Risk assessment tools are available for screening high risk patients and understanding the utility and limitations of these tools is important for all clinicians involved in the care of patients. There have been significant advances in breast cancer screening in the last several year including breast tomosynthesis, automated breast ultrasound, molecular imaging, as well as accelerated breast MRI protocols. This has raised the question: Do women at risk for breast cancer need additional breast cancer screening using these newer imaging modalities? In addition, with these advances in imaging, can women with atypical proliferative lesions be observed rather than undergoing surgical excision as some suggest? The role of observation, surgical excision and even prophylactic mastectomy in women with atypical proliferative lesions continues to be debated; however there is data that can guide physicians in the management of these patients. Pleomorphic Lobular carcinoma in-situ (PLCIS) is a distinct pathological entity within LCIS and there is no consensus regarding surgical margins or the need for adjuvant treatment to prevent recurrence. Recently, ductal carcinoma in-situ (DCIS) has been the subject of much controversy: is it truly a cancer or is it instead a precursor lesion. The traditional management of DCIS with lumpectomy and radiation is now being debated and recent data demonstrates that low grade DCIS can be managed with observation. Clinical trials are now accruing patients with low and intermediate grade DCIS to observation and close surveillance, and not surgical excision. Finally, new guidelines for chemoprevention with the use of tamoxifen and raloxifen for women with atypical proliferative lesions, LCIS, PLCIS, and DCIS are available and should be discussed as an option when guiding management of these patients. This book will provide a comprehensive review of this field and will serve as a valuable resource for clinicians, general surgeons, breast surgeons and surgical oncologists, as well as researchers with an interest in the management of atypical breast lesions. The book will review new data about breast cancer, risk factors for breast cancer, pathological features unique to each entity, the characteristic findings on imaging, risk stratification for genetic testing, as well as the current evidence-based management of each of these breast lesions. Our text will provide assessment tools for risk prediction of breast cancer. We will provide data on the current imaging modalities, as well as advanced screening options available for diagnosis and following these patients. Current management of many of these lesions continues to be controversial in regard to observation with close surveillance versus the need for surgical excision of these lesions based on future risk or whether these lesions are precursor lesion. For ductal carcinoma in-situ, the debate continues in regards to whether this disease entity is a precursor lesion that can be managed with observation or hormonal therapy, or is DCIS cancer and treated with lumpectomy and radiation. Several studies have been published where patients are managed with observation and treatment with hormonal therapy before surgical management. New trials have already begun accruing patients with low to intermediate grade DCIS where patients will be managed with observation versus hormonal therapy only. Management of DCIS continues to evolve and current management will be discussed This text will provide a concise but comprehensive summary of the current management of patients with atypical breast proliferative lesions and some benign breast lesions and will help guided management of these patients. All chapters in this text will be written by experts in the field in each of these disease entities. They will all include the most up to date research and clinical information to enhance our understanding and treatment of patients.
Book Synopsis MicroRNA Expression Patterns in Precursor Lesions and (hereditary) Breast Cancer by : Liqiang Qi
Download or read book MicroRNA Expression Patterns in Precursor Lesions and (hereditary) Breast Cancer written by Liqiang Qi and published by . This book was released on 2009 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cancer Precursors by : Eduardo L. Franco
Download or read book Cancer Precursors written by Eduardo L. Franco and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Precursors is a groundbreaking, multidisciplinary text containing a comprehensive overview of methodological issues associated with the study of pre-cancerous conditions, as well as reviews of the contributions of descriptive, analytical, and molecular epidemiological research to knowledge about cancer precursors at specific anatomical locations. The research focuses on the early natural history of cancers, by helping to define the etiology of precursor lesions, improving the means of detecting them either directly or via testing of surrogate biomarkers, and by elucidating the role of remote causes leading to the early onset of such lesions.
Book Synopsis WHO Classification of Tumours of the Breast by : Sunil R. Lakhani
Download or read book WHO Classification of Tumours of the Breast written by Sunil R. Lakhani and published by World Health Organization. This book was released on 2012 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Breast is the fourth volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 90 authors from 24 countries, contains more than 340 colour photographs, tables and figures, and more than 1600 references.
Book Synopsis Cancer Precursor Conditions and Their Detection, an Issue of Hematology/Oncology Clinics of North America by : Elizabeth K O'Donnell, MD
Download or read book Cancer Precursor Conditions and Their Detection, an Issue of Hematology/Oncology Clinics of North America written by Elizabeth K O'Donnell, MD and published by Elsevier Health Sciences. This book was released on 2024-08-28 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editor Dr. Elizabeth K. O'Donnell brings her considerable expertise to the topic of Cancer Precursor Syndromes and Their Detection. Top experts focus on cancer precursors for different sites, with articles on the risk-benefit analysis of early interception; plasma cell precursors; early detection and interception of lung cancer, cervical cancer, GI cancers, skin cancer; and head and neck cancer; biomarkers and early detection; and more. Contains 12 relevant, practice-oriented topics including clonal hematopoiesis of indeterminate potential (CHIP); prostate cancer: early detection and intervention; ductal carcinoma in situ; cancer prevention; and more. Provides in-depth clinical reviews on cancer precursor syndromes and their detection, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Book Synopsis Advances in Surgical Pathology: Breast Cancer by : Omar Hameed
Download or read book Advances in Surgical Pathology: Breast Cancer written by Omar Hameed and published by LWW. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest, groundbreaking addition to the Advances in Surgical Pathology series, Breast Cancer offers a thorough overview of the disease and the most recent data and technologies used in breast cancer surgery and diagnosis. Whether you're a new or experienced pathologist or oncologist, or prepping for boards or certification, this is an irreplaceable volume. Key Features: NEW and updated information on molecular subtypes, predictive and prognostic markers, premalignant and precursor lesions. Coverage of topics including: intraductal papillary carcinoma and variants; microinvasive carcinoma; invasive micropapillary carcinoma More than 250 full-color photos and ultrasound images illustrate the content Special focus on the convergence of pathology and radiology Chapters cover areas including: cytology; imaging and gross features; histology; differential diagnosis; immunohistochemistry; pathogenesis; and molecular genetics of each cancer type
Book Synopsis Molecular Pathology of Breast Cancer by : Sunil Badve
Download or read book Molecular Pathology of Breast Cancer written by Sunil Badve and published by Springer. This book was released on 2016-11-26 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in proteome. Newer assays that allow greater stability and analytical consistency are emerging. These alterations in tumor profiles can be also now detected by imaging techniques. The heterogeneity of both tumor and tumor microenvironment, an inevitable reality, is discussed in detail with particular focus on cancer stem cells and immune signaling. A chapter is dedicated to the emerging technology of “liquid biopsy”, which opens a novel approach for “continuous” monitoring of cancer that might be superior to conventional diagnostics, “Molecular Pathology of Breast Cancer” provides a quick and easy, not to mention essential, tour for clinicians, pathologists and scientists who are seeking to understand the integration of molecular biology into the diagnosis, prognosis and management of breast cancer.
Book Synopsis Monoclonality and Genetic Instability in Premalignant Breast Tissue by : Carol L. Rosenberg
Download or read book Monoclonality and Genetic Instability in Premalignant Breast Tissue written by Carol L. Rosenberg and published by . This book was released on 2000 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: By the time a cancer is detected, its tumor cells already exhibit myriad genetic abnormalities. To gain a better understanding of genetic events that occur early in breast carcinogenesis, this research examined genetic abnormalities 1) in histologically normal tissue from women at low, medium or high degrees of breast cancer risk, using archival specimens of reduction mammoplasties, and of diagnoses of atypical hyperplasia and breast cancers, respectively; and 2) in synchronously occurring putative precursor lesions, including normal-appearing epithelium, simple and atypical proliferative (hyperplastic) lesions and carcinomas themselves. Each specimen is microdissected, its DNA examined using a panel of selected microsatellite markers, and evidence of clonal abnormalities sought, in particular loss of heterozygosity (LOH) and microsatellite instability (MI). Investigation of the project's first goal generated data regarding the timing and sites of early genetic abnormalities. These data raise the possibility that a field defect exists in certain breast tissue. Investigation of the second goal is uncovering that a variety of clonal relationships exist between multiple synchronous putative precursors. These studies are identifying important sites of genetic abnormalities in early breast cancer precursors, and begin to outline a sequence of acquired genetic abnormalities needed for precursor lesions to evolve into full-blown malignancies.
Book Synopsis Bathsheba's Breast by : James S. Olson
Download or read book Bathsheba's Breast written by James S. Olson and published by JHU Press. This book was released on 2005-02-09 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: " ... An absorbing narrative history of breast cancer told through the heroic stories of women who have confronted the disease."--Back cover.
Book Synopsis Ductal Carcinoma in Situ of the Breast by :
Download or read book Ductal Carcinoma in Situ of the Breast written by and published by . This book was released on 2020 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Should I Be Tested for Cancer? by : H. Gilbert Welch
Download or read book Should I Be Tested for Cancer? written by H. Gilbert Welch and published by Univ of California Press. This book was released on 2006-03-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thought-provoking volume, a physician and public health expert challenges the notion that detecting cancer early always saves lives.
Book Synopsis Pancreatic Cancer by : Douglas B. Evans
Download or read book Pancreatic Cancer written by Douglas B. Evans and published by Springer Science & Business Media. This book was released on 2006-04-18 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.
Book Synopsis Digital Breast Tomosynthesis by : Alberto Tagliafico
Download or read book Digital Breast Tomosynthesis written by Alberto Tagliafico and published by Springer. This book was released on 2016-05-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive description of the screening and clinical applications of digital breast tomosynthesis (DBT) and offers straightforward, clear guidance on use of the technique. Informative clinical cases are presented to illustrate how to take advantage of DBT in clinical practice. The importance of DBT as a diagnostic tool for both screening and diagnosis is increasing rapidly. DBT improves upon mammography by depicting breast tissue on a video clip made of cross‐sectional images reconstructed in correspondence with their mammographic planes of acquisition. DBT results in markedly reduced summation of overlapping breast tissue and offers the potential to improve mammographic breast cancer surveillance and diagnosis. This book will be an excellent practical teaching guide for beginners and a useful reference for more experienced radiologists.
Book Synopsis Pathology and Genetics of Tumours of the Breast and Female Genital Organs by : World Health Organization
Download or read book Pathology and Genetics of Tumours of the Breast and Female Genital Organs written by World Health Organization and published by IARC. This book was released on 2003 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the 5th volume in a WHO series on histological and genetic typing of human tumours. This edition focuses on cancers of the breast and female genital organs, and describes diagnostic criteria, pathological features, associated genetic alterations and gene expression patterns in a disease-oriented manner. Sections on all recognised neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics and predictive factors. It contains colour photographs, X-rays, computed tomography (CT) and magnetic resonance (MR) images, charts and over 3,200 references. The classifications presented reflect the views of WHO working group conferences held in France in January and March 2002, and the volume was produced in collaboration with the International Academy of Pathology.
