Alpha-Keto Acid Dehydrogenase Complexes

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Author :
Publisher : Nelson Thornes
ISBN 13 : 9783764351816
Total Pages : 338 pages
Book Rating : 4.3/5 (518 download)

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Book Synopsis Alpha-Keto Acid Dehydrogenase Complexes by : M.S. Patel

Download or read book Alpha-Keto Acid Dehydrogenase Complexes written by M.S. Patel and published by Nelson Thornes. This book was released on 1996-02-29 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: These systems have medical importance in areas ranging from defects in regulation (linked to diabetes, heart disease, obesity, nutrition defects), to inherited diseases (inborn errors, maple syrup urine disease) to acquired immune diseases (primary biliary cirrhosis).

Branched-chain Amino Acids

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Publisher : Academic Press
ISBN 13 : 0121822257
Total Pages : 587 pages
Book Rating : 4.1/5 (218 download)

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Book Synopsis Branched-chain Amino Acids by : Robert Allison Harris

Download or read book Branched-chain Amino Acids written by Robert Allison Harris and published by Academic Press. This book was released on 2000 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 324 of Methods in Enzymology supplements Volume 166. It includes genetic information (cloning, gene expression) and information on human genetic diseases not available when Volume 166 was published.

Alpha-Keto Acid Dehydrogenase Complexes

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Author :
Publisher : Birkhäuser
ISBN 13 : 303488981X
Total Pages : 321 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Alpha-Keto Acid Dehydrogenase Complexes by : M.S. Patel

Download or read book Alpha-Keto Acid Dehydrogenase Complexes written by M.S. Patel and published by Birkhäuser. This book was released on 2012-12-06 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Found in all organisms, the alpha-keto acid dehydrogenase complexes have central roles in cellular metabolism and are major sites of regulation. The understanding of the organization, function and regulation of these quintessential multienzyme complexes has been greatly advanced by studies employing molecular biology and biophysical techniques. Although these enzyme systems have some features in common, their diversity in fulfilling unique organism - or tissue - specific roles is truly amazing. These systems have medical importance in areas ranging from defects in regulation (linked to diabetes, heart disease, obesity, nutrition defects), to inherited diseases (inborn errors, maple syrup urine disease) to acquired immune diseases (primary biliary cirrhosis). This book brings together wide-ranging recent findings on the structure(function relationships, gene regulation, and genetic defects of the alpha-keto acid dehydrogenase complexes, namely the pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and the branched-chain alpha-keto acid dehydrogenase complexes. A wide variety of experimental approaches together with new results presented in this book should serve as a resource for beginning to established investigators in the field as well as scientists who are interested in mitochondria, dehydrogenases, kinases, phosphatases, lipoic acid, thiamine pyrophosphate, and enzyme complexes.

A Study of Enzymes

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Author :
Publisher : CRC Press
ISBN 13 : 9780849369889
Total Pages : 646 pages
Book Rating : 4.3/5 (698 download)

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Book Synopsis A Study of Enzymes by : Stephen A. Kuby

Download or read book A Study of Enzymes written by Stephen A. Kuby and published by CRC Press. This book was released on 1990-11-16 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive monograph consists of two parts: Volume I, entitled Enzyme Catalysis, Kinetics, and Substrate Binding; and Volume II, entitled Mechanism of Enzyme Action. Volume I focuses on several aspects of enzyme catalytic behavior, their steady-state and transient-state kinetics, and the thermodynamic properties of substrate binding. Packed with figures, tables, schemes, and photographs, this volume contains over 1,000 references, including references regarding enzymology's fascinating history. This comprehensive book is of particular interest to enzymology students, teachers, and researchers. Volume II presents selected "cutting edge" examples of techniques and approaches being pursued in biochemistry. This up-to-date resource includes 11 chapters, which illustrate important theoretical and practical aspects of enzyme mechanisms. It also features selected examples in which today's most important techniques, ideas, and theories are used to elaborate on the intricate nature of enzyme action mechanisms. This particular volume provides important information for both the novice and the seasoned investigator.

Class 2 Transferases

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Publisher : Springer Science & Business Media
ISBN 13 : 3540856994
Total Pages : 480 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Class 2 Transferases by : Antje Chang

Download or read book Class 2 Transferases written by Antje Chang and published by Springer Science & Business Media. This book was released on 2010-04-03 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

Research Awards Index

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Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metabolism in Cancer

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Publisher : Springer
ISBN 13 : 3319421182
Total Pages : 272 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Metabolism in Cancer by : Thorsten Cramer

Download or read book Metabolism in Cancer written by Thorsten Cramer and published by Springer. This book was released on 2016-08-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

The Glutamate/GABA-Glutamine Cycle

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Author :
Publisher : Springer
ISBN 13 : 3319450964
Total Pages : 420 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis The Glutamate/GABA-Glutamine Cycle by : Arne Schousboe

Download or read book The Glutamate/GABA-Glutamine Cycle written by Arne Schousboe and published by Springer. This book was released on 2016-11-25 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book. A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.

Introduction to Epigenetics

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Author :
Publisher : Springer Nature
ISBN 13 : 3030686701
Total Pages : 215 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Introduction to Epigenetics by : Renato Paro

Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

The Enzymes

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Publisher : Academic Press
ISBN 13 : 0121227189
Total Pages : 525 pages
Book Rating : 4.1/5 (212 download)

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Book Synopsis The Enzymes by : Paul D. Boyer

Download or read book The Enzymes written by Paul D. Boyer and published by Academic Press. This book was released on 1970 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Class 2 Transferases X

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540478183
Total Pages : 643 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Class 2 Transferases X by : Dietmar Schomburg

Download or read book Class 2 Transferases X written by Dietmar Schomburg and published by Springer Science & Business Media. This book was released on 2007-11-19 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

The Enzymes

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Author :
Publisher : Academic Press
ISBN 13 : 008086595X
Total Pages : 525 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis The Enzymes by :

Download or read book The Enzymes written by and published by Academic Press. This book was released on 1987-03-19 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Enzymes

Class 1 Oxidoreductases V

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783540225140
Total Pages : 654 pages
Book Rating : 4.2/5 (251 download)

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Book Synopsis Class 1 Oxidoreductases V by : Dietmar Schomburg

Download or read book Class 1 Oxidoreductases V written by Dietmar Schomburg and published by Springer Science & Business Media. This book was released on 2004-10-20 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Each volume comprises one enzyme class, sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.

Biochemistry for Medical Professionals

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Publisher : Academic Press
ISBN 13 : 0128020113
Total Pages : 112 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biochemistry for Medical Professionals by : Tsugikazu Komoda

Download or read book Biochemistry for Medical Professionals written by Tsugikazu Komoda and published by Academic Press. This book was released on 2015-06-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry for Medical Professionals contains pivotal advances in the biochemistry field and provides a resource for professionals across medicine, dentistry, pharmaceutical sciences and health professions who need a concise, topical biochemistry reference. Relevant, well-illustrated coverage begins with the composition of the human body and then goes into the technical detail of the metabolism of the human body and biochemistry of internal organs before featuring a biotechnology study inclusive of numerous methods and applications. The work is written at a consistently high level, with technical notes added to aid comprehension for complex topics. - Illustrates disease involvement in metabolic maps - Contains coverage of cutting-edge technology, including iPS, HPLC and HPLC-MS, and FACS method - Provides in-depth technical detail as well as conceptual frameworks of biochemistry and experimental design in the context of the human organism - Includes a biotechnology study, featuring application of basic biochemistry principles

Biomedical Index to PHS-supported Research

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Author :
Publisher :
ISBN 13 :
Total Pages : 866 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biomedical Index to PHS-supported Research by :

Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1990 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Biochemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 3642196233
Total Pages : 380 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Essentials of Biochemistry by : Herbert J. Fromm

Download or read book Essentials of Biochemistry written by Herbert J. Fromm and published by Springer Science & Business Media. This book was released on 2012-01-05 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook, Essentials of Biochemistry is aimed at chemistry and biochemistry undergraduate students and first year biochemistry graduate students. It incorporates the lectures of the authors given to students with a strong chemistry background. An emphasis is placed on metabolism and reaction mechanisms and how they are studied. As the title of the book implies, the text lays the basis for an understanding of the fundamentals of biochemistry.

Modulation by Covalent Modification

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Author :
Publisher : Elsevier
ISBN 13 : 1483217264
Total Pages : 570 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Modulation by Covalent Modification by : Shmuel Shaltiel

Download or read book Modulation by Covalent Modification written by Shmuel Shaltiel and published by Elsevier. This book was released on 2014-06-28 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Cellular Regulation: Volume 27, Modulation by Covalent Modification is a compendium of papers dealing with the coordination, function, or control of cellular metabolism, particularly on modulation by covalent modification. One paper reviews the cyclic cascade model in metabolic regulation that shows the model's applicability to all covalent interconvertible enzyme systems, such as those modified by phosphorylation, ADP-ribosylation, carboxymethylation, acetylation, and sulfation. Another paper discusses the hypothesis that smooth muscle contraction is regulated by a calcium-dependent phosphorylation of the myosin molecule. Studies made by Sellers and Pato suggest that a phosphatase isolated from turkey gizzard muscle (known as smooth muscle phosphatase IV) can be related to an in vivo myosin phosphatase as the phosphatase IV binds well to both myosin and thiophosphorylated myosin. Other papers describe in situ regulation studies of Excherichia coli glutamine synthethase, the posttranslational processing of the insulin proreceptor, and selenium in cellular metabolism. The compendium is suitable for biochemists, microbiologists, and academicians whose works involve research in cell biology.