Skeletal stem/progenitor cells and their environment in bone regeneration

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Publisher : Frontiers Media SA
ISBN 13 : 2832543634
Total Pages : 146 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Skeletal stem/progenitor cells and their environment in bone regeneration by : Celine Colnot

Download or read book Skeletal stem/progenitor cells and their environment in bone regeneration written by Celine Colnot and published by Frontiers Media SA. This book was released on 2024-01-26 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skeleton plays essential physiological functions throughout life from structural support and movement for the entire body, to storage of minerals and hematopoiesis, as well as endocrine functions. Skeletal integrity is maintained by the efficient remodeling and repair abilities of bone tissue that involves multiple skeletal stem/progenitor cell (SSPC) populations within bone compartments. These populations change their properties during development, growth and aging and can be affected by disease and trauma. SSPCs also interact with bone marrow, blood vessels, nerves, and adjacent soft tissues. The close communication between various skeletal and extra-skeletal cell populations is required for bone maintenance and function, and during bone regeneration following injury or trauma. Tremendous advances have been made in the past decade on the characterization of SSPCs that support skeletal regeneration. Yet, we still do not fully understand the basic cellular and molecular mechanisms underlying the high regenerative potential of bone and how disease or trauma can reduce SSPC functions and lead to impaired healing.

Mechanobiology

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Publisher : Elsevier
ISBN 13 : 0128179325
Total Pages : 256 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mechanobiology by : Glen L. Niebur

Download or read book Mechanobiology written by Glen L. Niebur and published by Elsevier. This book was released on 2019-12-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena

Osteoporosis

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Publisher : Springer Nature
ISBN 13 : 3319692879
Total Pages : 518 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Osteoporosis by : Benjamin Z. Leder

Download or read book Osteoporosis written by Benjamin Z. Leder and published by Springer Nature. This book was released on 2020-01-31 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, and utilizing the most current evidence and practice guidelines for the treatment of osteoporosis, this comprehensive third edition discusses the basic aspects of bone metabolism, the pathophysiology of osteoporosis, current diagnostic techniques and medical treatment strategies. Osteoporosis is a common disorder that is prevalent in over 20 million Americans over the age of 60. One and a half million osteoporotic fractures occur in the United States every year, including 300,000 hip fractures. Mortality rates after hip fracture approach 25%, with another 50% of patients experiencing a major decrease in their prior level of independence and quality of life. Despite the wide prevalence and severe consequences of osteoporosis, it remains a disorder that is severely under-diagnosed and treated. In this context, specialists and primary care physicians alike are having increasing difficulty keeping up with the rapid changes to the field and incorporating these advances to clinical care. In the years since the last edition of this book was published, the osteoporosis field has changed drastically. In addition to revising and updating existing chapters and removing a few that are no longer as relevant, new chapters discuss an advanced understanding of the cellular and molecular mechanisms underlying the disorder, the introduction of new diagnostic imaging techniques, a more nuanced appreciation of the risks and benefits of osteoporosis therapies, and the introduction of two new classes of osteoporosis medications. Following the format of the second edition, and including helpful key points at the opening of each chapter, this text will present a comprehensive overview of both the basic and clinical concepts relating to each topic, when appropriate. Chapter authors were chosen based on their high level of expertise and leadership in the field. Taken together, this text should thus be of great interest to physicians of multiple specialties, allied health professionals, as well as basic and clinical researchers.

Cellular Mechanotransduction

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Publisher : Cambridge University Press
ISBN 13 : 9781107682467
Total Pages : 0 pages
Book Rating : 4.6/5 (824 download)

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Book Synopsis Cellular Mechanotransduction by : Mohammad R. K. Mofrad

Download or read book Cellular Mechanotransduction written by Mohammad R. K. Mofrad and published by Cambridge University Press. This book was released on 2014-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Mechanotransduction" is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.

Osteoporosis and Osteoarthritis

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Publisher : Humana
ISBN 13 : 9781071609880
Total Pages : 302 pages
Book Rating : 4.6/5 (98 download)

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Book Synopsis Osteoporosis and Osteoarthritis by : Andre J. van Wijnen

Download or read book Osteoporosis and Osteoarthritis written by Andre J. van Wijnen and published by Humana. This book was released on 2020-12-07 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed second edition provides key updates on well-established methods as well as coverage of recently emerging sophisticated techniques and methods that are essential for an in-depth and state-of-the-art understanding of skeletal development and homeostasis and the pathological mechanisms that cause skeletal degeneration. The first half of the book examines cell and molecular biological aspects of osteoarthritis and osteoporosis, while the remainder of the collection focuses on in vivo models of skeletal tissue injury, degeneration, and repair. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Osteoporosis and Osteoarthritis, Second Edition aims to assist investigators concerned with research topics broadly related to osteoporosis, osteoarthritis, intervertebral disc degeneration, as well as other musculoskeletal disorders.

Phylogenomic Approaches to Deal with Particularly Challenging Plant Lineages

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Publisher : Frontiers Media SA
ISBN 13 : 2889663671
Total Pages : 171 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Phylogenomic Approaches to Deal with Particularly Challenging Plant Lineages by : Marcial Escudero

Download or read book Phylogenomic Approaches to Deal with Particularly Challenging Plant Lineages written by Marcial Escudero and published by Frontiers Media SA. This book was released on 2021-01-08 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Omics Technologies and Bio-engineering

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Publisher : Academic Press
ISBN 13 : 0128047496
Total Pages : 645 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Omics Technologies and Bio-engineering by : Debmalya Barh

Download or read book Omics Technologies and Bio-engineering written by Debmalya Barh and published by Academic Press. This book was released on 2017-12-01 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care. - Covers various aspects of biotechnology and bio-engineering using omics technologies - Focuses on the latest developments in the field, including biofuel technologies - Provides key insights into omics approaches in personalized and precision medicine - Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

Connectome

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Publisher : HMH
ISBN 13 : 0547508174
Total Pages : 389 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis Connectome by : Sebastian Seung

Download or read book Connectome written by Sebastian Seung and published by HMH. This book was released on 2012-02-07 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Accessible, witty . . . an important new researcher, philosopher and popularizer of brain science . . . on par with cosmology’s Brian Greene and the late Carl Sagan” (The Plain Dealer). One of the Wall Street Journal’s 10 Best Nonfiction Books of the Year and a Publishers Weekly “Top Ten in Science” Title Every person is unique, but science has struggled to pinpoint where, precisely, that uniqueness resides. Our genome may determine our eye color and even aspects of our character. But our friendships, failures, and passions also shape who we are. The question is: How? Sebastian Seung is at the forefront of a revolution in neuroscience. He believes that our identity lies not in our genes, but in the connections between our brain cells—our particular wiring. Seung and a dedicated group of researchers are leading the effort to map these connections, neuron by neuron, synapse by synapse. It’s a monumental effort, but if they succeed, they will uncover the basis of personality, identity, intelligence, memory, and perhaps disorders such as autism and schizophrenia. Connectome is a mind-bending adventure story offering a daring scientific and technological vision for understanding what makes us who we are, as individuals and as a species. “This is complicated stuff, and it is a testament to Dr. Seung’s remarkable clarity of exposition that the reader is swept along with his enthusiasm, as he moves from the basics of neuroscience out to the farthest regions of the hypothetical, sketching out a spectacularly illustrated giant map of the universe of man.” —TheNew York Times “An elegant primer on what’s known about how the brain is organized and how it grows, wires its neurons, perceives its environment, modifies or repairs itself, and stores information. Seung is a clear, lively writer who chooses vivid examples.” —TheWashington Post

Physics Of Cancer, The: Research Advances

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Publisher : World Scientific
ISBN 13 : 9811223505
Total Pages : 279 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Physics Of Cancer, The: Research Advances by : Bernard S Gerstman

Download or read book Physics Of Cancer, The: Research Advances written by Bernard S Gerstman and published by World Scientific. This book was released on 2020-12-03 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer deaths per capita have decreased in recent years, but the improvement is attributed to prevention, not treatment. The difficulty in treating cancer may be due to its 'complexity', in the mathematical physics sense of the word. Tumors evolve and spread in response to internal and external factors that involve feedback mechanisms and nonlinear behavior. Investigations of the nonlinear interactions among cells, and between cells and their environment, are crucial for developing a sufficiently detailed understanding of the system's emergent phenomenology to be able to control the behavior. In the case of cancer, controlling the system's behavior will mean the ability to treat and cure the disease. Physicists have been studying various complex, nonlinear systems for many years using a variety of techniques. These investigations have provided insights that allow physicists to make unique contributions towards the treatment of cancer.This interdisciplinary book presents recent advancements in physicists' research on cancer. The work presented in this volume uses a variety of physical, biochemical, mathematical, theoretical, and computational techniques to gain a deeper molecular and cellular understanding of the horrific disease that is cancer.

The Law of Bone Remodelling

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Publisher : Springer Science & Business Media
ISBN 13 : 364271031X
Total Pages : 339 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Law of Bone Remodelling by : Julius Wolff

Download or read book The Law of Bone Remodelling written by Julius Wolff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translated from the German by Maquet, P.; Furlong, R.

Fanged Noumena

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Publisher : MIT Press
ISBN 13 : 095530878X
Total Pages : 678 pages
Book Rating : 4.9/5 (553 download)

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Book Synopsis Fanged Noumena by : Nick Land

Download or read book Fanged Noumena written by Nick Land and published by MIT Press. This book was released on 2011-04-01 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dizzying trip through the mind(s) of the provocative and influential thinker Nick Land. During the 1990s British philosopher Nick Land's unique work, variously described as “rabid nihilism,” “mad black deleuzianism,” and “cybergothic,” developed perhaps the only rigorous and culturally-engaged escape route out of the malaise of “continental philosophy” —a route that was implacably blocked by the academy. However, Land's work has continued to exert an influence, both through the British “speculative realist” philosophers who studied with him, and through the many cultural producers—writers, artists, musicians, filmmakers—who have been invigorated by his uncompromising and abrasive philosophical vision. Beginning with Land's early radical rereadings of Heidegger, Nietzsche, Kant and Bataille, the volume collects together the papers, talks and articles of the mid-90s—long the subject of rumour and vague legend (including some work which has never previously appeared in print)—in which Land developed his futuristic theory-fiction of cybercapitalism gone amok; and ends with his enigmatic later writings in which Ballardian fictions, poetics, cryptography, anthropology, grammatology and the occult are smeared into unrecognisable hybrids. Fanged Noumena gives a dizzying perspective on the entire trajectory of this provocative and influential thinker's work, and has introduced his unique voice to a new generation of readers.

Bone Remodeling Process

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Publisher : Academic Press
ISBN 13 : 0323902057
Total Pages : 238 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Bone Remodeling Process by : Rabeb Ben Kahla

Download or read book Bone Remodeling Process written by Rabeb Ben Kahla and published by Academic Press. This book was released on 2021-08-14 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation. - Each chapter covers a core topic in bone biomechanics - Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation - Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process

Polarization of Light

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110605090
Total Pages : 267 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Polarization of Light by : Maria Chekhova

Download or read book Polarization of Light written by Maria Chekhova and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-03-22 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book starts with the description of polarization in classical optics, including also a chapter on crystal optics, which is necessary to understand the use of nonlinear crystals. In addition, spatially non-uniform polarization states are introduced and described. Further, the role of polarization in nonlinear optics is discussed. The final chapters are devoted to the description and applications of polarization in quantum optics and quantum technologies.

The Relationship Between Neural Circuitry and Biomechanical Action

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Publisher : Frontiers Media SA
ISBN 13 : 2889745791
Total Pages : 331 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The Relationship Between Neural Circuitry and Biomechanical Action by : Redha Taiar

Download or read book The Relationship Between Neural Circuitry and Biomechanical Action written by Redha Taiar and published by Frontiers Media SA. This book was released on 2022-03-07 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanics of Cellular Bone Remodeling

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Publisher : CRC Press
ISBN 13 : 1466564164
Total Pages : 323 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Mechanics of Cellular Bone Remodeling by : Qing-Hua Qin

Download or read book Mechanics of Cellular Bone Remodeling written by Qing-Hua Qin and published by CRC Press. This book was released on 2013-01-08 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on bone remodeling has resulted in much new information and has led to improvements in design and biomedical practices. Mechanics of Cellular Bone Remodeling: Coupled Thermal, Electrical, and Mechanical Field Effects presents a unified exploration of recent advances, giving readers a sound understanding of bone remodeling and its mathematical representation. Beginning with a description of the basic concept of bone remodeling from a mathematical point of view, the book details the development of each of the techniques and ideas. From there it progresses to the derivation and construction of multifield and cellular bone remodeling and shows how they arise naturally in response to external multifield loads. Topics include: Fundamental concepts and basic formulations for bone remodeling Applications of formulations to multifield internal bone remodeling of inhomogeneous long cylindrical bone Theory and solution of multifield surface bone remodeling A hypothetical regulation mechanism on growth factors for bone modeling and remodeling under multifield loading The RANK–RANKL–OPG pathway and formulation for analyzing the bone remodeling process A model of bone cell population dynamics for cortical bone remodeling under mechanical and pulsed electromagnetic stimulus Recent developments in experiments with bone materials Readers will benefit from the thorough coverage of general principles for each topic, followed by detailed mathematical derivations and worked examples, as well as tables and figures where appropriate. The book not only serves as a reliable reference but is also destined to attract interested readers and researchers to a field that offers fascinating and technologically important challenges.

Tropomyosin

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Publisher : Springer Science & Business Media
ISBN 13 : 0387857664
Total Pages : 323 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Tropomyosin by : Peter Gunning

Download or read book Tropomyosin written by Peter Gunning and published by Springer Science & Business Media. This book was released on 2009-09-30 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recent review of one of my grant applications commented on the ‘rediscovery of tropomyosin’. I was tempted to write back in my rebuttal to the reviewer that I didn’t realise it had been lost. Uncharacteristic maturity prevailed and I resisted the temptation, but I was struck by the underlying observation that research on the str- ture and function of tropomyosin has been somewhat invisible, particularly in terms of the cytoskeleton isoforms. So, how can it be that one of the two major components of the actin filament has been so thoroughly overlooked? I suspect that the answer is disappointingly pedestrian. Whereas the biochemistry of the 1980s revealed the potential of tropomyosin isoforms to diversify the function of actin filaments, the subsequent disenchantment with isoform biology in general in the 1990s inhibited growth of this field. With the development of more sophisticated experimental - proaches we are now seeing a growing realisation of the importance of tropomyosin in regulating actin filaments beyond its pivotal role in muscle contraction. The opportunity to edit this book came at a time when we had written several reviews on different aspects of tropomyosin function and I had just finished the background reading for a comprehensive review of tropomyosin biology. I realised that the field was simply beyond the capacity of any one person to do the field j- tice.

Writings 1997–2003

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Author :
Publisher : MIT Press
ISBN 13 : 1915103134
Total Pages : 0 pages
Book Rating : 4.9/5 (151 download)

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Book Synopsis Writings 1997–2003 by : CCRU

Download or read book Writings 1997–2003 written by CCRU and published by MIT Press. This book was released on 2023-10-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: