Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories

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Author :
Publisher : National Academies Press
ISBN 13 : 0309225760
Total Pages : 216 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by : Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories

Download or read book Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories written by Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories and published by National Academies Press. This book was released on 2012-03-16 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories

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Author :
Publisher : National Academies Press
ISBN 13 : 0309225752
Total Pages : 216 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by : National Research Council

Download or read book Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories written by National Research Council and published by National Academies Press. This book was released on 2012-04-02 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Indo-U.S. Workshop on Challenges of Emerging Infections and Global Health Safety

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Publisher : National Academies Press
ISBN 13 : 0309378664
Total Pages : 215 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Indo-U.S. Workshop on Challenges of Emerging Infections and Global Health Safety by : Indian National Science Academy

Download or read book Indo-U.S. Workshop on Challenges of Emerging Infections and Global Health Safety written by Indian National Science Academy and published by National Academies Press. This book was released on 2016-06-13 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States and India have pledged to deepen the linkages between their people, their businesses, and their governments for the mutual benefit of both countries and for the promotion of global peace, stability, economic growth and prosperity. Both nations are now inclined to improve relations and cooperation, but the nations need specific actions that will yield progress and build confidence and momentum for further cooperation. The Indo-U.S. Workshop on Challenges of Emerging Infections and Global Health Safety, held in November 2014, encouraged scientists from both countries to examine global issues related to emerging and existing infections and global health safety, to share experience and approaches, and to identify opportunities for cooperation to improve practice and research in these areas. This report summarizes the presentations and discussions from the workshop.

Oversight of High-Containment Biological Laboratories

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Publisher : DIANE Publishing
ISBN 13 : 1437919375
Total Pages : 33 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Oversight of High-Containment Biological Laboratories by : Frank Gottron

Download or read book Oversight of High-Containment Biological Laboratories written by Frank Gottron and published by DIANE Publishing. This book was released on 2009-12 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fed. gov¿t. responded to the 9/11 terrorist attacks and the subsequent anthrax attacks with increased focus on and funding for biodefense. High-containment labs. (HCL) play a critical role in the biodefense effort, offering the hope of better responses to an attack and a better understanding of the threat posed by bioterrorism. However, they also could increase the risk of a biological attack by serving as a potential source of materials or training. Policymakers have become increasingly interested in the oversight of these facilities following reports of accidents, regulatory noncompliance, and community resistance. A key task for policymakers is to define their goals for enhancing oversight of HCL. Illustrations

Biosafety in Microbiological and Biomedical Laboratories

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Publisher :
ISBN 13 :
Total Pages : 156 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Biosafety in Microbiological and Biomedical Laboratories by : Centers for Disease Control (U.S.)

Download or read book Biosafety in Microbiological and Biomedical Laboratories written by Centers for Disease Control (U.S.) and published by . This book was released on 1988 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Potential Risks and Benefits of Gain-of-Function Research

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Publisher : National Academies Press
ISBN 13 : 0309367867
Total Pages : 140 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Potential Risks and Benefits of Gain-of-Function Research by : National Research Council

Download or read book Potential Risks and Benefits of Gain-of-Function Research written by National Research Council and published by National Academies Press. This book was released on 2015-04-13 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.

Laboratory Biorisk Management

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Publisher : CRC Press
ISBN 13 : 1498749747
Total Pages : 264 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Laboratory Biorisk Management by : Reynolds M. Salerno

Download or read book Laboratory Biorisk Management written by Reynolds M. Salerno and published by CRC Press. This book was released on 2015-12-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts

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Publisher : National Academies Press
ISBN 13 : 0309486564
Total Pages : 121 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts by : National Academies of Sciences, Engineering, and Medicine

Download or read book Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-05-01 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: On June 27-28, 2018, the U.S. National Academies of Sciences, Engineering, and Medicine (the National Academies) convened an international workshop in Amsterdam, the Netherlands, on developing norms for the provision of laboratories in low-resource contexts. The U.S. Department of State's Biosecurity Engagement Program requested that the National Academies organize this workshop to engage an international group of organizations that provide funding for construction, upgrades, and maintenance of biological laboratories in countries without the means to build such labs themselves. Twenty-one people from 19 organizations participated. The intent was to advance the conversation about the identification and application of guiding principles and common norms for use by these organizations in their grants, partnerships, and aid. This publication summarizes the presentations and discussions from the workshop.

Laboratory Biosecurity Handbook

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Publisher : CRC Press
ISBN 13 : 9781420006209
Total Pages : 208 pages
Book Rating : 4.0/5 (62 download)

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Book Synopsis Laboratory Biosecurity Handbook by : Reynolds M. Salerno

Download or read book Laboratory Biosecurity Handbook written by Reynolds M. Salerno and published by CRC Press. This book was released on 2007-06-21 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: By achieving a delicate balance between systems and practices, proper laboratory biosecurity reduces the risk of legitimate bioscience facilities becoming sources of pathogens and toxins for malicious use. Effective design and implementation of laboratory biosecurity depends on cooperation among individuals from diverse communities, including scientists, technicians, policy makers, security engineers, and law enforcement officials. Providing guidance to the broad international community, Laboratory Biosecurity Handbook addresses the objectives of biosecurity and the ways in which they overlap or conflict with those of biosafety. The book describes the risks of working with dangerous pathogens and toxins in the current era of international terrorism. The authors characterize the global spread of legitimate biotechnology and relate it to the rise of transnational terrorism, emphasizing the need for biosecurity measures even in legitimate bioscience. The book discusses biosecurity risk assessment-a practical methodology that allows laboratory management and biosafety/biosecurity officers to analyze and determine the level of risk, and serves as a basis for managing those risks. The book includes questionnaires that can assist the process of collecting data for a biosecurity vulnerability assessment, example standard operating procedures and memoranda of understanding, and other useful reference material. Addressing a variety of operating environments and the particular challenges they face when designing and implementing laboratory biosecurity, this book can assist bioscience facilities ranging from the large to the small, from those that focus on diagnosis or vaccine development, to those only minimally involved with infectious diseases. The detailed recommendations help avoid a "one-size-fits-all" approach to security and save limited resources. The book shows institutions how to develop and implement a biosecurity plan, and helps ensure that all components are included in the overall system, whether existing or new.

Viral Sovereignty and Technology Transfer

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Publisher : Cambridge University Press
ISBN 13 : 1108484727
Total Pages : 237 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Viral Sovereignty and Technology Transfer by : Sam F. Halabi

Download or read book Viral Sovereignty and Technology Transfer written by Sam F. Halabi and published by Cambridge University Press. This book was released on 2020-06-11 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sharing biological resources-critical for new medicines and vaccines-has declined as countries and scientists dispute rights over research.

Laboratory Biosafety Manual

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Publisher : World Health Organization
ISBN 13 : 9789241546508
Total Pages : 196 pages
Book Rating : 4.5/5 (465 download)

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Book Synopsis Laboratory Biosafety Manual by : World Health Organization

Download or read book Laboratory Biosafety Manual written by World Health Organization and published by World Health Organization. This book was released on 2004-12-28 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.

World at Risk

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Publisher : Vintage
ISBN 13 : 0307473260
Total Pages : 162 pages
Book Rating : 4.3/5 (74 download)

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Book Synopsis World at Risk by : Commission on Prevention/WMDs

Download or read book World at Risk written by Commission on Prevention/WMDs and published by Vintage. This book was released on 2008-12-03 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The greatest danger of another catastrophic attack in the United States will materialize if the world's most dangerous terrorists acquire the world's most dangerous weapons.” —The 9/11 Commission Report The bipartisan Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism was established by the U.S. Congress to build on the work of the 9/11 Commission by assessing our nation's progress in preventing weapons of mass destruction proliferation and terrorism, and providing a roadmap to greater security with concrete recommendations for improvement. The Commission has interviewed over 200 experts inside and outside of government. They have met with counterterrorism and intelligence officials here at home and abroad who are working to stop proliferation and terrorism The Commission's report examines the government's current policies and programs, identifies gaps in our government's prevention strategy and recommends ways to close them. The threat of terrorist attacks in the United States and elsewhere is still very real. The world remians at risk There is more that can and must be done. Our security depends on it.

The Handbook of Plant Biosecurity

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Publisher : Springer Science & Business Media
ISBN 13 : 940077365X
Total Pages : 723 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis The Handbook of Plant Biosecurity by : Gordon Gordh

Download or read book The Handbook of Plant Biosecurity written by Gordon Gordh and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook identifies all aspects of Regulatory Plant Biosecurity and discusses them from the standpoint of preventing the international movement of plant pests, diseases and weeds that negatively impact production agriculture, natural plant-resources and agricultural commerce.

Ensuring National Biosecurity

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Publisher : Academic Press
ISBN 13 : 0128018607
Total Pages : 270 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Ensuring National Biosecurity by : Carole R Baskin

Download or read book Ensuring National Biosecurity written by Carole R Baskin and published by Academic Press. This book was released on 2016-02-03 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ensuring National Biosecurity: Institutional Biosafety Committees reviews the various responsibilities and associated challenges Institutional Biosafety Committees (IBCs) face and proposes changes that may help improve this system and increase national biosecurity and worker safety. In recent years IBCs in academic and other institutions have been tasked with increasing levels of responsibility, overseeing work with recombinant genetic material and hazardous agents. IBC members often lack the training to effectively ensure that the work performed is truly safe for scientists and the general community, and so increasingly rely upon the expertise of the researchers themselves. With the proposed US dual-use research policies soon to be implemented, this strain may increase. This book provides readers with the necessary information to be able to enhance national biosecurity within the US, EU, Australia, New Zealand, Japan and more. Ensuring National Biosecurity is as an invaluable reference for biosafety professionals or for researchers who need to understand the regulatory landscape that impacts their research. Examines and assesses the current state of Institutional Biosafety Committees (IBCs) Collates contributions from world-renowned experts in fields as diverse as research compliance, law and astrobiology Reflects an international perspective on regulatory biosecurity and biosafety

Our Common Agenda - Report of the Secretary-General

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Publisher : United Nations
ISBN 13 : 9213583893
Total Pages : 194 pages
Book Rating : 4.2/5 (135 download)

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Book Synopsis Our Common Agenda - Report of the Secretary-General by : United Nations

Download or read book Our Common Agenda - Report of the Secretary-General written by United Nations and published by United Nations. This book was released on 2021-09-10 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: On the seventy-fifth anniversary of the United Nations, the world has faced its biggest shared test since the Second World War in the coronavirus disease (COVID-19) pandemic. Yet while our welfare, and indeed the permanence of human life, depend on us working together, international cooperation has never been harder to achieve. This report answers a call from UN Member States to provide recommendations to advance our common agenda and to respond to current and future challenges. Its proposals are grounded in a renewal of the social contract, adapted to the challenges of this century, taking into account younger and future generations, complemented by a new global deal to better protect the global commons and deliver global public goods. Through a deepening of solidarity—at the national level, between generations, and in the multilateral system—Our Common Agenda provides a path forward to a greener, safer and better future.

WHO Expert Committee on Biological Standardization

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Publisher : World Health Organization
ISBN 13 : 9240024379
Total Pages : 291 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO Expert Committee on Biological Standardization by :

Download or read book WHO Expert Committee on Biological Standardization written by and published by World Health Organization. This book was released on 2021-05-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seventy-second meeting of the WHO Expert Committee on Biological Standardization was held from 19 to 23 October 2020 by WebEx video conferencing due to the restrictions imposed during the coronavirus disease 2019 (COVID-19) pandemic. The meeting was opened on behalf of the Director-General of WHO by Dr Mariângela Batista Galvão Simão, Assistant Director-General, Access to Medicines and Health Products. Dr Simão welcomed Committee members, meeting participants and observers. Dr Simão began by noting that the Committee had met as recently as August 2020, primarily to address standardization activities related to COVID-19, and that much remains to be learnt about the pandemic. The WHO Solidarity Trial was continuing to facilitate the rapid and robust comparison of potential treatments. Recently published interim results indicated that the four small molecule treatments remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon had little or no benefit in terms of overall mortality or speed of recovery of hospitalized patients – to date only dexamethasone had proved to be effective against severe COVID-19.

Preparing for Future Products of Biotechnology

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Publisher : National Academies Press
ISBN 13 : 0309452058
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Preparing for Future Products of Biotechnology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Preparing for Future Products of Biotechnology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.