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Author : Nikolaĭ Konstantinovich Kochetkov
Publisher :
ISBN 13 :
Total Pages : 396 pages
Book Rating : 4.3/5 (91 download)
Download or read book Organic Chemistry of Nucleic Acids written by Nikolaĭ Konstantinovich Kochetkov and published by . This book was released on 1972 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Carsten Schmuck
Publisher : John Wiley & Sons
ISBN 13 : 3527604081
Total Pages : 600 pages
Book Rating : 4.5/5 (276 download)
Download or read book Highlights in Bioorganic Chemistry written by Carsten Schmuck and published by John Wiley & Sons. This book was released on 2006-01-24 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview. In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as * Artificial receptors for the stabilization of ß-sheet structures * Carbohydrate recognition by artificial receptors * Combinatorial chemistry as a tool for the discovery of catalysts * The interaction of NO and peroxynitrite with hemoglobin and myoglobin * Inhibitors against human mast-cell-tryptase as a potential approach to conquering asthma * The selectivity of DNA replication. A readily accessible survey for everyone wishing to stay abreast of developments. With a Foreword by Ronald Breslow.
Author : Ulf Diederichsen
Publisher : John Wiley & Sons
ISBN 13 : 3527296654
Total Pages : 487 pages
Book Rating : 4.5/5 (272 download)
Download or read book Bioorganic Chemistry written by Ulf Diederichsen and published by John Wiley & Sons. This book was released on 1999-12-16 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of (patho)physiological processes - the biosynthesis of biomolecules such as enzymes, nucleic acids, and secondary metabolites; the pathways of signaltransduction; or the function of pharmaceutical agents - is of increasing importance not only for drug research but also for the development of new synthetic methods in organic chemistry and biochemistry. In a truly interdisciplinary way bioorganic chemistry unites the central questions of biochemistry, medicinal chemistry, organic chemistry, and spectroscopy. This book fills a void in this rapidly growing field of chemistry and gives a thorough yet understandable introduction for advanced students and researchers alike. Contributions of more than sixty scientists provide a topical overview of recent advances in: drug development based on natural products; the biosynthesis, activity, and application of enzymes; carbohydrates; peptides; nucleic acids; analytical methods in bioorganic chemistry. This book will be an appetizer for all - students and researchers alike - seeking orientation in this fascinating field of chemistry.
Author : Sidney M. Hecht
Publisher : OUP USA
ISBN 13 : 9780195084672
Total Pages : 516 pages
Book Rating : 4.0/5 (846 download)
Download or read book Bioorganic Chemistry: Nucleic Acids written by Sidney M. Hecht and published by OUP USA. This book was released on 1996-07-11 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of DNA and RNA including coverage of biosynthesis, stucture, and their functions in information storage and transmission. A review of fundamental material is presented in the first half of each chapter followed by a fairly detailed research example selected by the chapter author from current research.
Author : Martin Egli
Publisher : Wiley-VCH
ISBN 13 : 9783906390673
Total Pages : 0 pages
Book Rating : 4.3/5 (96 download)
Download or read book Chemistry and Biology of Artificial Nucleic Acids written by Martin Egli and published by Wiley-VCH. This book was released on 2012-04-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to provide a comprehensive overview of the field of artificial nucleic acids. Covering a tremendous amount of literature on the chemistry, biology, and structure of artificial nucleic acids, it will constitute an invaluable source of information for the specialist and for young researchers interested in starting a career in this fascinating field of research alike. This book combines the contributions of many of the major players in this research field, and covers the synthesis of sugar-, base- and backbone-modified nucleic acids, their structural characteristics studied by X-ray crystallography, and NMR in solution as well as their chemical and biological properties.
Author : Valérie Gabelica
Publisher : Springer
ISBN 13 : 3642548423
Total Pages : 297 pages
Book Rating : 4.6/5 (425 download)
Download or read book Nucleic Acids in the Gas Phase written by Valérie Gabelica and published by Springer. This book was released on 2014-07-28 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet unsolved questions. Laboratory sciences have bloomed with a variety of techniques to decipher the properties of the molecules of life. This volume introduces techniques used to investigate the properties of nucleic acids in the absence of solvent. It highlights the specificities pertaining to the studies of nucleic acids, although some of the techniques can similarly be applied to the study of other biomolecules, like proteins. The first part of the book introduces the techniques, from the transfer of nucleic acids to the gas-phase, to their detailed physico-chemical investigation. Each chapter is devoted to a specific molecular property, and illustrates how various approaches (experimental and theoretical) can be combined for the interpretation. The second part of the book is devoted to applying the gas-phase approaches to solve specific questions related to the biophysics, biochemistry or pharmacology of nucleic acids.
Author : Volker A. Erdmann
Publisher : Springer Science & Business
ISBN 13 : 3642544525
Total Pages : 599 pages
Book Rating : 4.6/5 (425 download)
Download or read book Chemical Biology of Nucleic Acids written by Volker A. Erdmann and published by Springer Science & Business. This book was released on 2014-04-22 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of ionic liquids; new technologies enabling the modification of gene expression via editing of therapeutic genes; the use of riboswitches; the modification of mRNA cap regions; new approaches to detect appropriately modified RNAs with EPR spectroscopy and the use of parallel and high-throughput techniques for the analysis of the structure and new functions of nucleic acids. This volume discusses how chemistry can add new frontiers to the field of nucleic acids in molecular medicine, biotechnology and nanotechnology and is not only an invaluable source of information to chemists, biochemists and life scientists but will also stimulate future research.
Author :
Publisher :
ISBN 13 :
Total Pages : 562 pages
Book Rating : 4.3/5 (91 download)
Download or read book Nucleic Acids Symposium Series written by and published by . This book was released on 1991 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: No. 6- are papers presented at the Symposium on Nucleic Acids Chemistry.
Author :
Publisher :
ISBN 13 :
Total Pages : 544 pages
Book Rating : 4.F/5 ( download)
Download or read book Soviet Journal of Bioorganic Chemistry written by and published by . This book was released on 1987 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : S. N. Ananchenko
Publisher : Elsevier
ISBN 13 : 1483278832
Total Pages : 485 pages
Book Rating : 4.4/5 (832 download)
Download or read book Frontiers of Bioorganic Chemistry and Molecular Biology written by S. N. Ananchenko and published by Elsevier. This book was released on 2017-05-04 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers of Bioorganic Chemistry and Molecular Biology covers the proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, held in Moscow and Tashkent, USSR on September 25-October 2, 1978. This symposium is devoted to a discussion of the physico-chemical basis of life processes. This book contains 56 chapters, and reflects the results in the study of peptides and proteins, nucleic acids, polysaccharides, and other biopolymers. Other chapters deal with the study of low molecular regulators, including steroids, alkaloids, and antibiotics. This book also includes discussion of the achievements in the study of genetic structures and of cellular protein synthesizing systems of the molecular basis of enzymic catalysis and of bioenergetic processes. This book will be of value to biochemists and molecular biologists.
Author : Michael D. Greenberg
Publisher : John Wiley & Sons
ISBN 13 : 0470526262
Total Pages : 400 pages
Book Rating : 4.4/5 (75 download)
Download or read book Radical and Radical Ion Reactivity in Nucleic Acid Chemistry written by Michael D. Greenberg and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive coverage of radical reactive intermediates in nucleic acid chemistry and biochemistry The Wiley Series on Reactive Intermediates in Chemistry and Biology investigates reactive intermediates from the broadest possible range of disciplines. The contributions in each volume offer readers fresh insights into the latest findings, emerging applications, and ongoing research in the field from a diverse perspective. The chemistry and biochemistry of reactive intermediates is central to organic chemistry and biochemistry, and underlies a significant portion of modern synthetic chemistry. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides the only comprehensive review of the chemistry and biochemistry of nucleic acid radical intermediates. With contributions by world leaders in the field, the text covers a broad range of topics, including: A discussion of the relevant theory Ionization of DNA Nucleic acid sugar radicals Halopyrimidines Oxidative, reductive, and low energy electron transfer Electron affinity sensitizers Photochemical generative of reactive oxygen species Reactive nitrogen species Enediyne rearrangements Phenoxyl radicals A unique compilation on the cutting edge of our understanding, Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides an unparalleled resource to student and professional researchers in such fields as organic chemistry, biochemistry, molecular biology, and physical chemistry, as well as the industries associated with these disciplines.
Author : Günter Mayer
Publisher : John Wiley & Sons
ISBN 13 : 1119957265
Total Pages : 595 pages
Book Rating : 4.1/5 (199 download)
Download or read book The Chemical Biology of Nucleic Acids written by Günter Mayer and published by John Wiley & Sons. This book was released on 2011-06-17 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Author : N. Kochetkov
Publisher : Springer
ISBN 13 : 9781468429749
Total Pages : 371 pages
Book Rating : 4.4/5 (297 download)
Download or read book Organic Chemistry of Nucleic Acids written by N. Kochetkov and published by Springer. This book was released on 2012-03-19 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of nucleic acids is one of the most rapidly developing fields in modern science. The exceptionally important role of the nucleic acids as a key to the understanding of the nature of life is reflected in the enormous number of published works on the subject, including many outstanding monographs and surveys. The pathways of syn thesis and metabolism of nucleic acid,s and the many and varied biological functions of these biopolymers are examined with the utmost detail in the literature. Nearly as much attention has been paid to the macromolecular chemistry of the nucleic acids: elucidation of the size and shape of their molecules, the study of the physicochemical properties of their solutions, and the appropriate methods to be used in such research. The surveys of the chemistry of nucleic acids which have been published so far deal almost entirely with their synthesis and, in particular, with the synthetic chemistry of monomers (nucleosides and nucleotides) ; less attention has been paid to the synthesis of poly nucleotides. There is yet another highly important aspect of the chemistry of nucleic acids which is still in the formative stage, the study of the reactivity of nucleic acid macromolecules and their components. This can make an important contribution to the deter mination of the structure of these remarkable biopolymers and to the correct understanding of their biological functions.
Author : Nikolaĭ Konstantinovich Kochetkov
Publisher : Springer
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.:/5 (37 download)
Download or read book Organic Chemistry of Nucleic Acids written by Nikolaĭ Konstantinovich Kochetkov and published by Springer. This book was released on 1972-05 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of nucleic acids is one of the most rapidly developing fields in modern science. The exceptionally important role of the nucleic acids as a key to the understanding of the nature of life is reflected in the enormous number of published works on the subject, including many outstanding monographs and surveys. The pathways of syn thesis and metabolism of nucleic acids and the many and varied biological functions of these biopolymers are examined with the utmost detail in the literature. Nearly as much attention has been paid to the macromolecular chemistry of the nucleic acids: elucidation of the size and shape of their molecules, the study of the physicochemical properties of their solutions, and the appropriate methods to be used in such research. The surveys of the chemistry of nucleic acids which have been published so far deal almost entirely with their synthesis and, in particular, with the synthetic chemistry of monomers (nucleosides and nucleotides); less attention has been paid to the synthesis of poly nucleotides. There is yet another highly important aspect of the chemistry of nucleic acids which is still in the formative stage, the study of the reactivity of nucleic acid macromolecules and their components. This can make an important contribution to the deter mination of the structure of these remarkable biopolymers and to the correct 'understanding of their biological functions.
Author : Zoe A. Shabarova
Publisher : John Wiley & Sons
ISBN 13 : 352761592X
Total Pages : 603 pages
Book Rating : 4.5/5 (276 download)
Download or read book Advanced Organic Chemistry of Nucleic Acids written by Zoe A. Shabarova and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequencing, cloning, transcription - these are but a few key techniques behind the current breathtaking advances in molecular biology and biochemistry. As these methods continuosly diversify, biochemists need a sound chemical understanding to keep the pace. Chemists beginning working in the molecular biology lab need an introduction to this field from their point of view. This book serves both: it describes most of the known chemical reactions of nucleosides, nucleotides, and nucleic acids in sufficient detail to provide the desired background, and additionally, the fundamental relations between sequence, structure and functionality of nucleic acids are presented. The first edition of this book, which was published in Russian, has immediately become a recognized standard reference. This second, thoroughly revised and updated edition, now published in English, is likely to achieve a similar position in the international scientific community.
Author : Eugene E. Van Tamelen
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.:/5 (318 download)
Download or read book Bioorganic Chemistry: Macro- and multimolecular systems written by Eugene E. Van Tamelen and published by . This book was released on 1977 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Band 3.
Author : David Van Vranken
Publisher : Garland Science
ISBN 13 : 1135054827
Total Pages : 504 pages
Book Rating : 4.1/5 (35 download)
Download or read book Introduction to Bioorganic Chemistry and Chemical Biology written by David Van Vranken and published by Garland Science. This book was released on 2018-10-08 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science.
