Biomembrane Simulations

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Publisher : CRC Press
ISBN 13 : 1351060309
Total Pages : 258 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Biomembrane Simulations by : Max L. Berkowitz

Download or read book Biomembrane Simulations written by Max L. Berkowitz and published by CRC Press. This book was released on 2019-04-30 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to recent advancements in the development of numerical algorithms and computational hardware, computer simulations of biological membranes, often requiring use of substantial computational resources, are now reaching a mature stage. Since molecular processes in membranes occur on a multitude of spatial and time scales, molecular simulations of membranes can also serve as a testing ground for use of multi-scale simulation techniques. This book addresses some of the important issues related to understanding properties and behavior of model biological membranes and it Shows how simulations improve our understanding of biological membranes and makes connections with experimental results. Presents a careful discussion of the force fields used in the membrane simulations including detailed all-atom fields and coarse-grained fields. Presents a continuum description of membranes. Discusses a variety of issues such as influence of membrane surfaces on properties of water, interaction between membranes across water, nanoparticle permeation across the membrane, action of anesthetics and creation of inhomogeneous regions in membranes. Discusses important methodological issues when using simulations to examine phenomena such as pore creation and permeation across membranes. Discusses progress recently achieved in modeling bacterial membranes. It will be a valuable resource for graduate students, researchers and instructors in biochemistry, biophysics, pharmacology, physiology, and computational biology.

Molecular Simulations and Biomembranes

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849732159
Total Pages : 331 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Molecular Simulations and Biomembranes by : Mark S P Sansom

Download or read book Molecular Simulations and Biomembranes written by Mark S P Sansom and published by Royal Society of Chemistry. This book was released on 2010-08-01 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for information in the understanding of membrane systems has been caused by three things - an increase in computer power; methodological developments and the recent expansion in the number of researchers working on it worldwide. However, there has been no up-to-date book that covers the application of simulation methods to membrane systems directly and this book fills an important void in the market. It provides a much needed update on the current methods and applications as well as highlighting recent advances in the way computer simulation can be applied to the field of membranes and membrane proteins. The objectives are to show how simulation methods can provide an important contribution to the understanding of these systems. The scope of the book is such that it covers simulation of membranes and membrane proteins, but also covers the more recent methodological developments such as coarse-grained molecular dynamics and multiscale approaches in systems biology. Applications embrace a range of biological processes including ion channel and transport proteins. The book is wide ranging with broad coverage and a strong coupling to experimental results wherever possible, including colour illustrations to highlight particular aspects of molecular structure. With an internationally respected list of authors, its publication is timely and it will prove indispensable to a large scientific readership.

Computational Modeling of Membrane Bilayers

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Author :
Publisher : Academic Press
ISBN 13 : 0080879705
Total Pages : 493 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Computational Modeling of Membrane Bilayers by : V. Sundararajan

Download or read book Computational Modeling of Membrane Bilayers written by V. Sundararajan and published by Academic Press. This book was released on 2011-08-29 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. *Discusses the current stat of electrostatics in biomolecular simulations and future directions *Includes information on time and length scales in lipid bilayer simulations *Includes a chapter on the nature of lipid rafts

Molecular Simulations and Biomembranes

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Publisher : Royal Society of Chemistry
ISBN 13 : 0854041893
Total Pages : 272 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Molecular Simulations and Biomembranes by : Mark S. P. Sansom

Download or read book Molecular Simulations and Biomembranes written by Mark S. P. Sansom and published by Royal Society of Chemistry. This book was released on 2010 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for information in the understanding of membrane systems has been caused by three things - an increase in computer power; methodological developments and the recent expansion in the number of researchers working on it worldwide. However, there has been no up-to-date book that covers the application of simulation methods to membrane systems directly and this book fills an important void in the market. It provides a much needed update on the current methods and applications as well as highlighting recent advances in the way computer simulation can be applied to the field of membranes and membrane proteins. The objectives are to show how simulation methods can provide an important contribution to the understanding of these systems. The scope of the book is such that it covers simulation of membranes and membrane proteins, but also covers the more recent methodological developments such as coarse-grained molecular dynamics and multiscale approaches in systems biology. Applications embrace a range of biological processes including ion channel and transport proteins. The book is wide ranging with broad coverage and a strong coupling to experimental results wherever possible, including colour illustrations to highlight particular aspects of molecular structure. With an internationally respected list of authors, its publication is timely and it will prove indispensable to a large scientific readership.

Membranes

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Publisher : Springer
ISBN 13 : 3319453157
Total Pages : 155 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Membranes by : Alfredo Maciel-Cerda

Download or read book Membranes written by Alfredo Maciel-Cerda and published by Springer. This book was released on 2016-11-09 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes current advances in the research on membranes and applications in industry, groundwater, and desalination processes. Topics range from synthesis of new polymers to preparation of membranes using new water treatments for effluents, graphite membranes, development of polymeric and ceramic materials for production of membranes intended to separate gases and liquids, and liquid-liquid phases. The authors include materials used to produce catalytic membranes for polymer synthesis. The book also details theoretical approaches and simulation of membrane processes and parameters and design.

Biomembrane Frontiers

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Publisher : Springer Science & Business Media
ISBN 13 : 160761314X
Total Pages : 337 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Biomembrane Frontiers by : Thomas Jue

Download or read book Biomembrane Frontiers written by Thomas Jue and published by Springer Science & Business Media. This book was released on 2009-06-13 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second book in the Handbook of Modern Biophysics series, dedicated to fundamental topics and new applications in biophysics. This book on biomembranes covers theory and application and includes problem sets, references and guides for further study.

Advances in Biomembranes and Lipid Self-Assembly

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Author :
Publisher : Academic Press
ISBN 13 : 0128050802
Total Pages : 224 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Advances in Biomembranes and Lipid Self-Assembly by :

Download or read book Advances in Biomembranes and Lipid Self-Assembly written by and published by Academic Press. This book was released on 2016-04-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Elsevier book series Advances in Biomembranes and Lipid Self-Assembly (previously titled Advances in Planar Lipid Bilayers and Liposomes), provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes, and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature and find their application in the formulation of biomimetic model membranes and in the design of artificial dispersion of liposomes. Moreover, lipids self-assemble into a wide range of other structures including micelles and the liquid crystalline hexagonal and cubic phases. Consensus has been reached that curved membrane phases do play an important role in nature as well, especially in dynamic processes such as vesicles fusion and cell communication. Self-assembled lipid structures have enormous potential as dynamic materials ranging from artificial lipid membranes to cell membranes, from biosensing to controlled drug delivery, from pharmaceutical formulations to novel food products to mention a few. An assortment of chapters in this volume represents both original research as well as comprehensive reviews written by world leading experts and young researchers. Surveys recent theoretical and experimental results on lipid micro- and nanostructures Presents potential uses of applications like clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering, and food products Provides both original research as well as comprehensive reviews written by world leading experts and young researchers Provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes, and lipid self-assemblies from the micro- to the nanoscale.

Polymer Membranes/Biomembranes

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642104789
Total Pages : 245 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Polymer Membranes/Biomembranes by : Wolfgang Peter Meier

Download or read book Polymer Membranes/Biomembranes written by Wolfgang Peter Meier and published by Springer Science & Business Media. This book was released on 2009-12-16 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Themulticomponentnatureofbiologicalmembranesandtheirintra- andextracel- lar interactions make direct investigations on the membrane structure and processes nearly impossible. Clearly, a better understanding of the membrane properties and the mechanisms determining membrane protein functions is crucial to the imp- mentation of biosensors, bioreactors and novel platforms for medical therapy. For this reason, the interest in model systems suitable for the construction and study of complex lipid/protein membrane architectures has increased steadily over the years. The classical portfolio of model membranes used for biophysical and - terfacial studies of lipid (bi)layers and lipid/protein composites includes Langmuir monolayers assembled at the water/air interface, (uni- and multi-lamellar) vesicles in bulk (liposomal) dispersion, bimolecular lipid membranes (BLMs), and various types of solid-supported membranes. All these have speci?c advantages but also suffer from serious drawbacksthat limit their technical applications. Polymer m- branes comprised of entirely synthetic or hybrid (synthetic polymer/biopolymer) block copolymersappeared to be an attractive alternative to the lipid-based models. Generally, the synthetic block copolymer membranes are thicker and more stable and the versatility of polymer chemistry allows the adoption of relevant properties for a wide range of applications. This volume provides a vast overview of the physico-chemical and synthetic - pectsofarti?cial membranes. Numerousmembranemodelsaredescribed, including their properties(i. e. swelling, drying, lateral mobility, stability, electrical conduct- ity, etc. ), advantages, and drawbacks. The potential applications of these models are discussed and supported by real examples. Chapter 1 summarizesmethodsfor the stabilizationof arti?cial lipid membranes.

Multiresponsive Behavior of Biomembranes and Giant Vesicles

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Author :
Publisher : Academic Press
ISBN 13 : 0128174846
Total Pages : 328 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Multiresponsive Behavior of Biomembranes and Giant Vesicles by :

Download or read book Multiresponsive Behavior of Biomembranes and Giant Vesicles written by and published by Academic Press. This book was released on 2019-11-27 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomembranes consist of molecular bilayers with many lipid and protein components. The fluidity of these bilayers allows them to respond to different environmental cues by changing their local molecular composition as well as their shape and topology. On the nanometer scale, this multi-responsive behavior can be studied by molecular dynamics simulations, which provide both snapshots and movies of the bilayer conformations. The general conceptual framework for these simulations is provided by the theory of curvature elasticity. The latter theory also explains the behavior of giant vesicles as observed by optical microscopy on the micrometer scale. The present volume describes new insights as obtained from recent developments in analytical theory, computer simulations, and experimental approaches. The seven chapters of the volume are arranged in a bottom-up manner from smaller to larger scales. These chapters address the refined molecular dynamics and multiscale modeling of biomembranes, their morphological complexity and adhesion, the engulfment and endocytosis of nanoparticles, the fusion of giant unilamellar vesicles, as well as recent advances in microfluidic technology applied to model membranes. Bridging the gap between lipid molecules and giant unilamellar vesicles (GUVs) Integrated view obtained from analytical theory, computer simulations, and experimental observations Multiresponsive behavior and morphological complexity of biomembranes

Computational Modeling of Membrane Bilayers

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Publisher : Academic Press
ISBN 13 : 0080920500
Total Pages : 493 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Computational Modeling of Membrane Bilayers by : V. Sundararajan

Download or read book Computational Modeling of Membrane Bilayers written by V. Sundararajan and published by Academic Press. This book was released on 2011-08-29 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. Discusses the current state of electrostatics in biomolecular simulations and future directions Includes information on time and length scales in lipid bilayer simulations Includes a chapter on the nature of lipid rafts

Biomedical Applications of Biophysics

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Publisher : Springer Science & Business Media
ISBN 13 : 160327233X
Total Pages : 249 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Biomedical Applications of Biophysics by : Thomas Jue

Download or read book Biomedical Applications of Biophysics written by Thomas Jue and published by Springer Science & Business Media. This book was released on 2010-08-18 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In keeping with goal and style of the Handbook in Modern Biophysics series, the proposed book will maintain a chapter structure that contains two parts: concepts and biological application. The book also integrates all the chapters into a smooth, continuous discourse. The first and second chapters establish the mathematical methods and theoretical framework underpinning the different topics in the rest if the book. Other chapters will use the theoretical framework as a basis to discuss optical and NMR approaches. Each chapter will contain innovative didactic elements that facilitate teaching, self-study, and research preparation (key points, summary, exercise, references).

Physics of Biological Membranes

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Publisher : Springer
ISBN 13 : 3030006301
Total Pages : 623 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Physics of Biological Membranes by : Patricia Bassereau

Download or read book Physics of Biological Membranes written by Patricia Bassereau and published by Springer. This book was released on 2018-12-30 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.

Biological Membranes

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Publisher : Springer Science & Business Media
ISBN 13 : 1468485806
Total Pages : 596 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Biological Membranes by : Kenneth M. Merz

Download or read book Biological Membranes written by Kenneth M. Merz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interface between a living cell and the surrounding world plays a critical role in numerous complex biological processes. Sperm/egg fusion, virus/cell fusion, exocytosis, endocytosis, and ion permeation are a few examples of processes involving membranes. In recent years, powerful tools such as X-ray crystal lography, electron microscopy, nuclear magnetic resonance, and infra-red and Raman spectroscopy have been developed to characterize the structure and dy namics of biomembranes. Despite this progress, many of the factors responsible for the function of biomembranes are still not well understood. The membrane is a very complicated supramolecular liquid-crystalline structure that is largely composed of lipids, forming a bilayer, to which proteins and other biomolecules are anchored. Often, the lipid bilayer environment is pictured as a hydropho bic structureless slab providing a thermodynamic driving force to partition the amino acids of a membrane protein according to their solubility. However, much of the molecular complexity of the phospholipid bilayer environment is ignored in such a simplified view. It is likely that the atomic details of the polar head group region and the transition from the bulk water to the hydrophobic core of the membrane are important. An understanding of the factors responsible for the function of biomembranes thus requires a better characterization at the molec ular level of how proteins interact with lipid molecules, of how lipids affect protein structure and of how lipid molecules might regulate protein function.

Biophysical Approaches for the Study of Membrane Structure Part B

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Author :
Publisher : Elsevier
ISBN 13 : 0443295670
Total Pages : 630 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Biophysical Approaches for the Study of Membrane Structure Part B by :

Download or read book Biophysical Approaches for the Study of Membrane Structure Part B written by and published by Elsevier. This book was released on 2024-07-21 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysical Approaches for the Study of Membrane Structure, Part B, Volume 701 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties—such as composition, phase state, or lateral stress—exhibit many fascinating new characteristics, but also pose a host of challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Characterization of domain formation in complex membranes: Analyzing the bending modulus from simulations of complex membranes, The density-threshold affinity: Calculating lipid binding affinities from unbiased Coarse-Grain Molecular Dynamics simulations, and much more. Additional sections cover Uncertainty quantification for trans-membrane stresses and moments from simulation, Using molecular dynamics simulations to generate small-angle scattering curves and cryo-EM images of proteoliposomes, Binary Bilayer Simulations for Partitioning Within Membranes, Modeling Asymmetric Cell Membranes at All-atom Resolution, Multiscale remodeling of biomembranes and vesicles, Building complex membranes with Martini 3, Predicting lipid sorting in curved bilayer membranes, Simulating asymmetric membranes using P21 periodic boundary conditions, and many other interesting topics. Explore the state-of-the-art of lipid membrane asymmetry Covers experimental, theoretical, and computational techniques to create and characterize asymmetric lipid membranes Teaches how these kinds of approaches create and characterize laterally inhomogeneous membranes

Modeling in Membranes and Membrane-Based Processes

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Publisher : John Wiley & Sons
ISBN 13 : 1119536065
Total Pages : 412 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Modeling in Membranes and Membrane-Based Processes by : Anirban Roy

Download or read book Modeling in Membranes and Membrane-Based Processes written by Anirban Roy and published by John Wiley & Sons. This book was released on 2020-04-07 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Modeling in Membranes and Membrane-Based Processes is based on the idea of developing a reference which will cover most relevant and “state-of-the-art” approaches in membrane modeling. This book explores almost every major aspect of modeling and the techniques applied in membrane separation studies and applications. This includes first principle-based models, thermodynamics models, computational fluid dynamics simulations, molecular dynamics simulations, and artificial intelligence-based modeling for membrane separation processes. These models have been discussed in light of various applications ranging from desalination to gas separation. In addition, this breakthrough new volume covers the fundamentals of polymer membrane pore formation mechanisms, covering not only a wide range of modeling techniques, but also has various facets of membrane-based applications. Thus, this book can be an excellent source for a holistic perspective on membranes in general, as well as a comprehensive and valuable reference work. Whether a veteran engineer in the field or lab or a student in chemical or process engineering, this latest volume in the “Advances in Membrane Processes” is a must-have, along with the first book in the series, Membrane Processes, also available from Wiley-Scrivener.

Biomembrane Phase Behavior and Anhydrobiotic Preservation in Model Membranes

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Publisher :
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.:/5 (79 download)

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Book Synopsis Biomembrane Phase Behavior and Anhydrobiotic Preservation in Model Membranes by : Sandra Viviana Bennun Serrano

Download or read book Biomembrane Phase Behavior and Anhydrobiotic Preservation in Model Membranes written by Sandra Viviana Bennun Serrano and published by . This book was released on 2008 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Functional Heterogeneities in Biomembranes

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889712486
Total Pages : 372 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Functional Heterogeneities in Biomembranes by : Rainer A. Böckmann

Download or read book Functional Heterogeneities in Biomembranes written by Rainer A. Böckmann and published by Frontiers Media SA. This book was released on 2021-09-01 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: