Biomedical Research Medicine And Disease

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Toward Precision Medicine

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309222222
Total Pages : 142 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Toward Precision Medicine by : National Research Council

Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Biomedical Research, Medicine, and Disease

Author : RC Sobti
Publisher : CRC Press
ISBN 13 : 1000811190
Total Pages : 665 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Biomedical Research, Medicine, and Disease by : RC Sobti

Download or read book Biomedical Research, Medicine, and Disease written by RC Sobti and published by CRC Press. This book was released on 2023-04-04 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical research is the first step towards the creation of new medications and treatments that help to manage different types of health conditions and diseases. The prevention and cure of diseases would be practically impossible without such type of research. Although the drug discovery and development processes are far too costly, time-consuming, prone to failure, and have low success rate, today the term "translational research or medicine" seems to have become trendy, yet it is insufficient. The present book is a sincere attempt by dedicated researchers to convey the importance of translational biomedical research, medicine, and disease, primarily, basic and clinical difficulties in the translation of diagnostic measures, pharmaceutical advances, biomarkers, diagnostics, and therapeutics. This book is meant for researchers, scientists, healthcare professionals, industry, innovators, and students of biomedical sciences, as well as for those involved in the basic sciences, biochemistry, biotechnology, biophysics, and life sciences in general. The volume comprehensively covers: Emerging technologies for health care Various aspects of biomedical research toward understanding of pathophysiology of the diseases Advances in improvement in diagnostic procedures and therapeutic tools The fundamental role of biomedical research in the development of new medicinal products

The Zebrafish in Biomedical Research

Author : Samuel Cartner
Publisher : Academic Press
ISBN 13 : 0128124326
Total Pages : 720 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Zebrafish in Biomedical Research by : Samuel Cartner

Download or read book The Zebrafish in Biomedical Research written by Samuel Cartner and published by Academic Press. This book was released on 2019-11-22 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

War and Disease

Author : Leo Barney Slater
Publisher : Rutgers University Press
ISBN 13 : 0813544386
Total Pages : 266 pages
Book Rating : 4.8/5 (135 download)

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Book Synopsis War and Disease by : Leo Barney Slater

Download or read book War and Disease written by Leo Barney Slater and published by Rutgers University Press. This book was released on 2009 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fighting around the globe, American soldiers were at high risk for contracting malaria, yet quinine - a natural cure - became hard to acquire. This historical study shows the roots and branches of an enormous drug development project during World War II.

Advancing the Nation's Health Needs

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309094275
Total Pages : 187 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Advancing the Nation's Health Needs by : National Research Council

Download or read book Advancing the Nation's Health Needs written by National Research Council and published by National Academies Press. This book was released on 2005-08-13 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report is the twelfth assessment of the National Institutes of Health National Research Service Awards program. The research training needs of the country in basic biomedical, clinical, and behavioral and social sciences are considered. Also included are the training needs of oral health, nursing, and health services research. The report has been broadly constructed to take into account the rapidly evolving national and international health care needs. The past and present are analyzed, and predictions with regard to future needs are presented.

Nonhuman Primates in Biomedical Research

Author : Christian R. Abee
Publisher : Academic Press
ISBN 13 : 0123978386
Total Pages : 868 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Nonhuman Primates in Biomedical Research by : Christian R. Abee

Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-06-07 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout

A Practical Guide to Biomedical Research

Author : Peter Agger
Publisher : Springer
ISBN 13 : 3319635824
Total Pages : 184 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis A Practical Guide to Biomedical Research by : Peter Agger

Download or read book A Practical Guide to Biomedical Research written by Peter Agger and published by Springer. This book was released on 2017-10-27 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book advises and supports novice researchers in taking their first steps into the world of scientific research. Through practical tips and tricks presented in a clear, concise and step-wise manner, the book describes the entire research process from idea to publication. It also gives the reader insight into the vast opportunities a research career can provide. The books target demographic is aspiring researchers within the biomedical professions, be it medical students, young doctors, nurses, engineers, physiotherapists etc. The book will help aspirational inexperienced researchers turn their intentions into actions, providing crucial guidance for successful entry into the field of biomedical research.

The Common Marmoset in Captivity and Biomedical Research

Author : Robert P. Marini
Publisher : Academic Press
ISBN 13 : 012811830X
Total Pages : 572 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Common Marmoset in Captivity and Biomedical Research by : Robert P. Marini

Download or read book The Common Marmoset in Captivity and Biomedical Research written by Robert P. Marini and published by Academic Press. This book was released on 2018-11-19 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications Includes contributions from renowned and international authors and editors Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

Integrative Approaches for Health

Author : Bhushan Patwardhan
Publisher : Academic Press
ISBN 13 : 0128014342
Total Pages : 383 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Integrative Approaches for Health by : Bhushan Patwardhan

Download or read book Integrative Approaches for Health written by Bhushan Patwardhan and published by Academic Press. This book was released on 2015-03-31 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite spectacular advances, modern medicine faces formidable global challenges in several key areas—notably the persistence of major killer diseases such as malaria, tuberculosis, leprosy, and newer threats including HIV/AIDS, resistant infections, and Ebola. As such, modern medicine has not led to a significant decrease in chronic diseases like diabetes, obesity, and other degenerative and autoimmune diseases. The authors believe that modern medicine needs to experience a paradigm shift, an integration of traditions—in particular from the ancient systems like Ayurveda and Yoga. Integrative Approaches for Health: Biomedical Research, Ayurveda and Yoga brings together the basic principles of interdisciplinary systems approach for an evolving construct of future medicine. Such an approach is already emerging at the cutting edge of current research in omics, bioinformatics, computational and systems biology. Several leading institutions of medicine have adopted Yoga and complementary medicine to widen their reach, and deepen effectiveness in therapeutic practices. The amalgam of modern medicine, with its strengths in scientific rigor, blended with the basic principles of life drawn from Ayurveda and Yoga might evolve into a medicine of tomorrow. Integrative approaches are no longer alternative, perhaps taking these approaches is the only possible way to heal our sick planet. This book introduces important trends and tools for biomedical researchers and physicians alike, to innovate the practice of medicine for the better. Contains a harmonious confluence of ancient and modern concepts, historical perspectives, philosophical underpinnings, and a relevant review of literature supported by worldwide case studies. Provides a critical analysis of ancient wisdom, pointing to potential areas for future research, which provide food for thought for public debate on integrative health care for the twenty-first century. Explains Ayurveda knowledge, and its relevance to drug discovery, nutrition, genomics, epigenetics, regenerative biology, longevity and personalized medicine. Shares Yoga knowledge insights, and explains its relevance to body–mind complex relationships, psychology, neurobiology, immunoendocrinology, bioenergetics, consciousness, and cognitive sciences. Offers illustrations and logic diagrams for enhanced understanding of the concepts presented.

The Mouse in Biomedical Research

Author :
Publisher : Elsevier
ISBN 13 : 0080469078
Total Pages : 829 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Mouse in Biomedical Research by :

Download or read book The Mouse in Biomedical Research written by and published by Elsevier. This book was released on 2006-12-15 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse’s normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Science, Medicine, and Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309101174
Total Pages : 23 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science, Medicine, and Animals by : National Research Council

Download or read book Science, Medicine, and Animals written by National Research Council and published by National Academies Press. This book was released on 2006-02-19 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science, Medicine, and Animals explains the role that animals play in biomedical research and the ways in which scientists, governments, and citizens have tried to balance the experimental use of animals with a concern for all living creatures. An accompanying Teacher's Guide is available to help teachers of middle and high school students use Science, Medicine, and Animals in the classroom. As students examine the issues in Science, Medicine, and Animals, they will gain a greater understanding of the goals of biomedical research and the real-world practice of the scientific method in general. Science, Medicine, and Animals and the Teacher's Guide were written by the Institute for Laboratory Animal Research and published by the National Research Council of the National Academies. The report was reviewed by a committee made up of experts and scholars with diverse perspectives, including members of the U.S. Department of Agriculture, National Institutes of Health, the Humane Society of the United States, and the American Society for the Prevention of Cruelty to Animals. The Teacher's Guide was reviewed by members of the National Academies' Teacher Associates Network. Science, Medicine, and Animals is recommended by the National Science Teacher's Association NSTA Recommends.

Enhancing the Vitality of the National Institutes of Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309089670
Total Pages : 165 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Enhancing the Vitality of the National Institutes of Health by : National Research Council

Download or read book Enhancing the Vitality of the National Institutes of Health written by National Research Council and published by National Academies Press. This book was released on 2003-08-29 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The report says that important organizational changes are needed at the National Institutes of Health to ensure the agency meets future challenges effectively. In particular, the report advises NIH to devote additional resources to innovative interdisciplinary research that reflects its strategic objectives and cuts across all agency's institutes and centers. The report recommends that Congress should establish a formal process for determining how specific proposals for changes in the number of NIH agencies and centers should be addressed.

Research in Medical and Biological Sciences

Author : Petter Laake
Publisher : Academic Press
ISBN 13 : 0128001542
Total Pages : 512 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Research in Medical and Biological Sciences by : Petter Laake

Download or read book Research in Medical and Biological Sciences written by Petter Laake and published by Academic Press. This book was released on 2015-06-05 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in Medical and Biological Sciences covers the wide range of topics that a researcher must be familiar with in order to become a successful biomedical scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences, this publication discusses a broad range of topics that are common yet not traditionally considered part of formal curricula, including philosophy of science, ethics, statistics, and grant applications. The information presented in this book also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. Covers the breadth of topics that a researcher must understand in order to be a successful experimental scientist Provides a broad scientific perspective that is perfect for students with various professional backgrounds Contains easily accessible, concise material about diverse methods Includes extensive online resources such as further reading suggestions, data files, statistical tables, and the StaTable application package Emphasizes the ethics and statistics of medical and biological sciences

Sourcebook of Models for Biomedical Research

Author : P. Michael Conn
Publisher : Springer Science & Business Media
ISBN 13 : 1588299333
Total Pages : 756 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Sourcebook of Models for Biomedical Research by : P. Michael Conn

Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Research in the Biomedical Sciences

Author : Michael Williams
Publisher : Academic Press
ISBN 13 : 0128047267
Total Pages : 382 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Research in the Biomedical Sciences by : Michael Williams

Download or read book Research in the Biomedical Sciences written by Michael Williams and published by Academic Press. This book was released on 2017-10-20 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in the Biomedical Sciences: Transparent and Reproducible documents the widespread concerns related to reproducibility in biomedical research and provides a best practices guide to effective and transparent hypothesis generation, experimental design, reagent standardization (including validation and authentication), statistical analysis, and data reporting. The book addresses issues in the perceived value of the existing peer review process and calls for the need for improved transparency in data reporting. It reflects new guidelines for publication that include manuscript checklists, replication/reproducibility initiatives, and the potential consequences for the biomedical research community and societal health and well-being if training, mentoring, and funding of new generations of researchers and incentives for publications are not improved. This book offers real world examples, insights, and solutions to provide a thought-provoking and timely resource for all those learning about, or engaged in, performing and supervising research across the biomedical sciences. Provides a “big picture perspective on the scope of reproducibility issues and covers initiatives that have potential as effective solutions Offers real-world research context for transparent, reproducible experimental design, execution and reporting of biomedical research with the potential to address aspects of the translational gap in drug discovery Highlights the importance of reproducibility and the necessary changes in biomedical and pharmaceutical research training and incentives to ensure sustainability

Biomedical Models and Resources

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309060354
Total Pages : 85 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Biomedical Models and Resources by : National Research Council

Download or read book Biomedical Models and Resources written by National Research Council and published by National Academies Press. This book was released on 1998-02-16 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Printbegrænsninger: Der kan printes 10 sider ad gangen og max. 40 sider pr. session.

The Minipig in Biomedical Research

Author : Peter A. McAnulty
Publisher : CRC Press
ISBN 13 : 1439811180
Total Pages : 713 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Minipig in Biomedical Research by : Peter A. McAnulty

Download or read book The Minipig in Biomedical Research written by Peter A. McAnulty and published by CRC Press. This book was released on 2011-12-19 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Minipig in Biomedical Research is a comprehensive resource for research scientists on the potential and use of the minipig in basic and applied biomedical research, and the development of drugs and chemicals. Written by acknowledged experts in the field, and drawing on the authors’ global contacts and experience with regulatory authorities and the pharmaceutical and other industries, this accessible manual ranges widely over the biological, scientific, and practical uses of the minipig in the laboratory. Its coverage extends from the minipig’s origins, anatomy, genetics, immunology, and physiology to its welfare, health, and husbandry; practical dosing and examination procedures; surgical techniques; and all areas of toxicity testing and the uses of the minipig as a disease model. Regulatory aspects of its use are considered. The reader will find an extensive amount of theoretical and practical information in the pharmacology; ADME and toxicology chapters which will help scientists and managers when deciding which species to use in basic research; drug discovery and pharmacology; and toxicology studies of chemicals, biotechnology products and devices. The book discusses regulatory uses of minipigs in the evaluation of human and veterinary pharmaceuticals, medical devices, and other classes of xenobiotics. It describes features of normal health, normal laboratory values, and common diseases. It also carefully elucidates ethical and legal considerations in their supply, housing, and transport. The result is an all-inclusive and up to date manual about the experimental uses of the minipig that describes ‘How to’ and ‘Why’ and ’What to expect in the normal’, combining enthusiasm and experience with critical assessment of its values and potential problems.