Biomedical Materials And Devices

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Biomedical Materials and Diagnostic Devices

Author : Ashutosh Tiwari
Publisher : John Wiley & Sons
ISBN 13 : 1118522931
Total Pages : 571 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Biomedical Materials and Diagnostic Devices by : Ashutosh Tiwari

Download or read book Biomedical Materials and Diagnostic Devices written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2012-10-16 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Materials and Diagnostics Devices provides an up-to-date overview of the fascinating and emerging field of biomedical materials and devices, fabrication, performance, and uses The biomedical materials with the most promising potential combine biocompatibility with the ability to adjust precisely the biological phenomena in a controlled manner. The world market for biomedical and diagnostic devices is expanding rapidly and the pace of academic research resulted in about 50,000 published papers in recent years. It is timely, therefore, to assemble a volume on this important subject. The chapters in the book seek to address progress in successful design strategies for biomedical materials and devices such as the use of collagen, crystalline calcium orthophosphates, amphiphilic polymers, polycaprolactone, biomimetic assembly, bio-nanocomposite matrices, bio-silica, theranostic nanobiomaterials, intelligent drug delivery systems, elastomeric nanobiomaterials, electrospun nano-matrices, metal nanoparticles, and a variety of biosensors. This large and comprehensive volume includes twenty chapters authored by some of the leading researchers in the field, and is divided into four main areas: biomedical materials; diagnostic devices; drug delivery and therapeutics; and tissue engineering and organ regeneration.

Biomedical Materials

Author : Roger Narayan
Publisher : Springer Science & Business Media
ISBN 13 : 038784872X
Total Pages : 573 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Biomedical Materials by : Roger Narayan

Download or read book Biomedical Materials written by Roger Narayan and published by Springer Science & Business Media. This book was released on 2009-06-20 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Materials provides a comprehensive discussion of contemporary biomaterials research and development. Highlighting important topics associated with Engineering, Medicine and Surgery, this volume reaches a wide scope of professionals, researchers and graduate students involved with biomaterials. A pedagogical writing style and structure provides readers with an understanding of the fundamental concepts necessary to pursue research and industrial work on biomaterials, including characteristics of biomaterials, biological processes, biocompatibility, and applications of biomaterials in implants and medical instruments. Written by leading researchers in the field, this text book takes readers to the forefront of biomedical materials development, providing them with a taste of how the field is changing, while also serving as a useful reference to physicians and engineers.

Biomedical Devices

Author : Raymond H. W. Lam
Publisher : Springer
ISBN 13 : 3030242374
Total Pages : 388 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Biomedical Devices by : Raymond H. W. Lam

Download or read book Biomedical Devices written by Raymond H. W. Lam and published by Springer. This book was released on 2019-08-16 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides essential knowledge for biomedical product development, including material properties, fabrication processes and design techniques for different applications, as well as process design and optimization. This book is multidisciplinary and readers can learn techniques to apply acquired knowledge for various applications of biomedical design. Further, this book encourages readers to discover and convert newly reported technologies into products and services for the future development of biomedical applications. This is an ideal book for upper-level undergraduate and graduate students, engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing. This book also: Provides a comprehensive set of fundamental knowledge for engineering students and entry level engineers to design biomedical devices Offers a unique approach to manufacturing of biomedical devices by integrating and formulating different considerations in process design tasks into optimization problems Provides a broad range of application examples to guide readers through the thinking process of designing and manufacturing biomedical devices, from basic understanding about the requirements and regulations to a set of manufacturing parameters

Joining and Assembly of Medical Materials and Devices

Author : Y N Zhou
Publisher : Elsevier
ISBN 13 : 0857096427
Total Pages : 583 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Joining and Assembly of Medical Materials and Devices by : Y N Zhou

Download or read book Joining and Assembly of Medical Materials and Devices written by Y N Zhou and published by Elsevier. This book was released on 2013-05-31 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications.Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications.Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. - Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices - Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires - Considers the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives

Metals for Biomedical Devices

Author : Mitsuo Niinomi
Publisher : Elsevier
ISBN 13 : 1845699246
Total Pages : 439 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Metals for Biomedical Devices by : Mitsuo Niinomi

Download or read book Metals for Biomedical Devices written by Mitsuo Niinomi and published by Elsevier. This book was released on 2010-03-31 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in medical devices using other materials, metallic implants are still one of the most commercially significant sectors of the industry. Given the widespread use of metals in medical devices, it is vital that the fundamentals and behaviour of this material are understood. Metals in biomedical devices reviews the latest techniques in metal processing methods and the behaviour of this important material.Initial chapters review the current status and selection of metals for biomedical devices. Chapters in part two discuss the mechanical behaviour, degradation and testing of metals with specific chapters on corrosion, wear testing and biocompatibility of biomaterials. Part three covers the processing of metals for biomedical applications with chapters on such topics as forging metals and alloys, surface treatment, coatings and sterilisation. Chapters in the final section discuss clinical applications of metals such as cardiovascular, orthopaedic and new generation biomaterials.With its distinguished editor and team of expert contributors, Metals for biomedical devices is a standard reference for materials scientists, researchers and engineers working in the medical devices industry and academia. - Reviews the latest techniques in metal processing methods including surface treatment and sterilisation - Examines metal selection for biomedical devices considering biocompatibility of various metals - Assesses mechanical behaviour and testing of metals featuring corrosion, fatigue and wear

Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach

Author : F.H. Silver
Publisher : Springer Science & Business Media
ISBN 13 : 9401107351
Total Pages : 310 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach by : F.H. Silver

Download or read book Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach written by F.H. Silver and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.

Biomaterials and Medical Devices

Author : Ferdyansyah Mahyudin
Publisher : Springer
ISBN 13 : 3319148451
Total Pages : 249 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Biomaterials and Medical Devices by : Ferdyansyah Mahyudin

Download or read book Biomaterials and Medical Devices written by Ferdyansyah Mahyudin and published by Springer. This book was released on 2016-02-26 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an introduction to biomaterials with the focus on the current development and future direction of biomaterials and medical devices research and development in Indonesia. It is the first biomaterials book written by selected academic and clinical experts experts on biomaterials and medical devices from various institutions and industries in Indonesia. It serves as a reference source for researchers starting new projects, for companies developing and marketing products and for governments setting new policies. Chapter one covers the fundamentals of biomaterials, types of biomaterials, their structures and properties and the relationship between them. Chapter two discusses unconventional processing of biomaterials including nano-hybrid organic-inorganic biomaterials. Chapter three addresses biocompatibility issues including in vitro cytotoxicity, genotoxicity, in vitro cell models, biocompatibility data and its related failure. Chapter four describes degradable biomaterial for medical implants, which include biodegradable polymers, biodegradable metals, degradation assessment techniques and future directions. Chapter five focuses on animal models for biomaterial research, ethics, care and use, implantation study and monitoring and studies on medical implants in animals in Indonesia. Chapter six covers biomimetic bioceramics, natural-based biocomposites and the latest research on natural-based biomaterials in Indonesia. Chapter seven describes recent advances in natural biomaterial from human and animal tissue, its processing and applications. Chapter eight discusses orthopedic applications of biomaterials focusing on most common problems in Indonesia, and surgical intervention and implants. Chapter nine describes biomaterials in dentistry and their development in Indonesia.

Metallic Biomaterials Processing and Medical Device Manufacturing

Author : Cuie Wen
Publisher : Woodhead Publishing
ISBN 13 : 0081029667
Total Pages : 606 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Metallic Biomaterials Processing and Medical Device Manufacturing by : Cuie Wen

Download or read book Metallic Biomaterials Processing and Medical Device Manufacturing written by Cuie Wen and published by Woodhead Publishing. This book was released on 2020-08-20 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering. - Reviews key topics of biomaterials processing for medical device applications including metallic biomaterials and their mechanical behavior, degradation, testing and characterization - Bridges the gap between biomaterials design and medical device manufacturing - Discusses the quality controls, standards, and FDA requirements for biomaterials and medical devices

Materials and Devices for Bone Disorders

Author : Susmita Bose
Publisher : Academic Press
ISBN 13 : 0128028033
Total Pages : 561 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Materials and Devices for Bone Disorders by : Susmita Bose

Download or read book Materials and Devices for Bone Disorders written by Susmita Bose and published by Academic Press. This book was released on 2016-11-03 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders. Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored. - Explores biomaterials for bone repair and related applications in orthopedics and dentistry in a clinical context - Introduces biomaterials applications in the context of specific diseases, bone disorders, and theraputic contexts - Includes input from a world-class team of research scientists, engineers, and clinicians - Covers the main types of bone disorder and disease including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders

Service Characteristics Of Biomedical Materials And Implants

Author : Andrew William Batchelor
Publisher : World Scientific
ISBN 13 : 1783260602
Total Pages : 260 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Service Characteristics Of Biomedical Materials And Implants by : Andrew William Batchelor

Download or read book Service Characteristics Of Biomedical Materials And Implants written by Andrew William Batchelor and published by World Scientific. This book was released on 2004-10-21 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: A wide variety of materials is being used in biomedical engineering for various functions. This includes a range of ceramics, polymers and metallic materials for implants and medical devices. A major question is how these materials will perform inside the body, which is very sensitive to alien materials. The material must not only survive to perform its intended function but also not initiate any damage to the surrounding tissue or induce a wider health problem. The service characteristics of implanted materials are of vital concern to health treatments that alleviate ageing.This book collates information and provides a concise text on the performance of different materials used in devices and implants. The knowledge presented is critical for a biomedical engineer, especially for the purpose of selecting the right materials. In addition, topics such as allergies and infection, tissue scaffolds, and drug delivery are reviewed.

Bioelectronics and Medical Devices

Author : Kunal Pal
Publisher : Woodhead Publishing
ISBN 13 : 9780081024201
Total Pages : 0 pages
Book Rating : 4.0/5 (242 download)

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Book Synopsis Bioelectronics and Medical Devices by : Kunal Pal

Download or read book Bioelectronics and Medical Devices written by Kunal Pal and published by Woodhead Publishing. This book was released on 2019-06-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioelectronics and Medical Devices: From Materials to Devices-Fabrication, Applications and Reliability reviews the latest research on electronic devices used in the healthcare sector, from materials, to applications, including biosensors, rehabilitation devices, drug delivery devices, and devices based on wireless technology. This information is presented from the unique interdisciplinary perspective of the editors and contributors, all with materials science, biomedical engineering, physics, and chemistry backgrounds. Each applicable chapter includes a discussion of these devices, from materials and fabrication, to reliability and technology applications. Case studies, future research directions and recommendations for additional readings are also included. The book addresses hot topics, such as the latest, state-of the-art biosensing devices that have the ability for early detection of life-threatening diseases, such as tuberculosis, HIV and cancer. It covers rehabilitation devices and advancements, such as the devices that could be utilized by advanced-stage ALS patients to improve their interactions with the environment. In addition, electronic controlled delivery systems are reviewed, including those that are based on artificial intelligences.

Materials for Biomedical Engineering

Author : Mohamed N. Rahaman
Publisher : John Wiley & Sons
ISBN 13 : 1119551080
Total Pages : 724 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Materials for Biomedical Engineering by : Mohamed N. Rahaman

Download or read book Materials for Biomedical Engineering written by Mohamed N. Rahaman and published by John Wiley & Sons. This book was released on 2021-11-23 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: MATERIALS FOR BIOMEDICAL ENGINEERING A comprehensive yet accessible introductory textbook designed for one-semester courses in biomaterials Biomaterials are used throughout the biomedical industry in a range of applications, from cardiovascular devices and medical and dental implants to regenerative medicine, tissue engineering, drug delivery, and cancer treatment. Materials for Biomedical Engineering: Fundamentals and Applications provides an up-to-date introduction to biomaterials, their interaction with cells and tissues, and their use in both conventional and emerging areas of biomedicine. Requiring no previous background in the subject, this student-friendly textbook covers the basic concepts and principles of materials science, the classes of materials used as biomaterials, the degradation of biomaterials in the biological environment, biocompatibility phenomena, and the major applications of biomaterials in medicine and dentistry. Throughout the text, easy-to-digest chapters address key topics such as the atomic structure, bonding, and properties of biomaterials, natural and synthetic polymers, immune responses to biomaterials, implant-associated infections, biomaterials in hard and soft tissue repair, tissue engineering and drug delivery, and more. Offers accessible chapters with clear explanatory text, tables and figures, and high-quality illustrations Describes how the fundamentals of biomaterials are applied in a variety of biomedical applications Features a thorough overview of the history, properties, and applications of biomaterials Includes numerous homework, review, and examination problems, full references, and further reading suggestions Materials for Biomedical Engineering: Fundamentals and Applications is an excellent textbook for advanced undergraduate and graduate students in biomedical materials science courses, and a valuable resource for medical and dental students as well as students with science and engineering backgrounds with interest in biomaterials.

Biomaterials in Translational Medicine

Author : Lei Yang
Publisher : Academic Press
ISBN 13 : 012813478X
Total Pages : 364 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biomaterials in Translational Medicine by : Lei Yang

Download or read book Biomaterials in Translational Medicine written by Lei Yang and published by Academic Press. This book was released on 2018-11-30 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. - Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine - Includes the translational or commercialization status of these new biomaterials - Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine - Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials

Biomaterials Engineering and Devices: Human Applications

Author : Donald L. Wise
Publisher : Springer Science & Business Media
ISBN 13 : 1592591973
Total Pages : 350 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Biomaterials Engineering and Devices: Human Applications by : Donald L. Wise

Download or read book Biomaterials Engineering and Devices: Human Applications written by Donald L. Wise and published by Springer Science & Business Media. This book was released on 2000-08-01 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medical device and drug industries standards in analytical methodology and are consistently among the strongest techno- quality control. logical performers. Materials are a key The users of Biomaterials Engineering ingredient in their dynamic growth. Devel- and Devices: Human Applications will r- opment of these materials is in a constant resent a broad base of backgrounds ranging state of activity, with the challenge of re- from the basic sciences (e. g. , polymer placing old materials that cannot withstand chemistry and biochemistry) to more the tests of time, and the new materials’ applied disciplines (e. g. , mechanical/ needs coming to the forefront in modern chemical engineering, orthopedics, and applications. This new reference text, pharmaceutics). To meet varied needs, each Biomaterials Engineering and Devices: chapter provides clear ancd fully detailed Human Applications, focuses on materials discussions. This in-depth, but practical, used in or on the human body—materials coverage should also assist recent indu- that define the world of “biomaterials. ” ees to the biomaterials circle. The editors Biomaterials Engineering and Devices: trust that this reference textbook conveys Human Applications focuses on mate- the intensity of this fast moving field in an rials development and characterization. enthusastic presentation. Chapters deal with issues in the selection of Donald L. Wise, PHD proper biomaterials from biocompatibility Debra J. Trantolo, PHD to biostability to structure/function relation- Kai-Uwe Lewandrowski, MD ships. Chapters also focus on the use of Joseph D. Gresser, PHD specific biomaterials based on their physio- Mario V.

Biomaterials, Medical Devices, and Combination Products

Author : Shayne Cox Gad
Publisher : CRC Press
ISBN 13 : 1482248387
Total Pages : 606 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Biomaterials, Medical Devices, and Combination Products by : Shayne Cox Gad

Download or read book Biomaterials, Medical Devices, and Combination Products written by Shayne Cox Gad and published by CRC Press. This book was released on 2015-12-01 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials, Medical Devices, and Combination Products is a single-volume guide for those responsible for-or concerned with-developing and ensuring patient safety in the use and manufacture of medical devices.The book provides a clear presentation of the global regulatory requirements and challenges in evaluating the biocompatibility and clinical

Medical Devices

Author : Seeram Ramakrishna
Publisher : Woodhead Publishing
ISBN 13 : 0081002912
Total Pages : 253 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Medical Devices by : Seeram Ramakrishna

Download or read book Medical Devices written by Seeram Ramakrishna and published by Woodhead Publishing. This book was released on 2015-08-18 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors' practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards. - Provides readers with a global perspective on medical device regulations - Concise and comprehensive information on how to design medical devices to ensure they meet regulations and standards - Includes a useful case study demonstrating the design and approval process

Biomedical Technology and Devices

Author : James E. Moore Jr
Publisher : CRC Press
ISBN 13 : 1439860610
Total Pages : 791 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Biomedical Technology and Devices by : James E. Moore Jr

Download or read book Biomedical Technology and Devices written by James E. Moore Jr and published by CRC Press. This book was released on 2013-06-25 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Technology and Devices, Second Edition focuses on the equipment, devices, and techniques used in modern medicine to diagnose, treat, and monitor human illnesses. Gathering together and compiling the latest information available on medical technology, this revised work adds ten new chapters. It starts with the basics, introducing the hist