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Biomarkers In Kidney Transplantation
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Book Synopsis Biomarkers in Kidney Transplantation by : Dr Smita Pattanaik
Download or read book Biomarkers in Kidney Transplantation written by Dr Smita Pattanaik and published by Academic Press. This book was released on 2024-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers. Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.
Book Synopsis Biomarkers of Renal Diseases by : Joaquín García-Estañ
Download or read book Biomarkers of Renal Diseases written by Joaquín García-Estañ and published by MDPI. This book was released on 2021-01-19 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides important and updated information on current research devoted to urinary biomarkers. Urinary biomarkers are characteristics that can be objectively measured and evaluated as indicators of normal biological or pathogenic processes of pharmacological responses to therapeutic intervention.
Book Synopsis Biomarkers in Kidney Disease by : Vinood B. Patel
Download or read book Biomarkers in Kidney Disease written by Vinood B. Patel and published by Springer. This book was released on 2016-03-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.
Book Synopsis Biomarkers of Kidney Disease by : Charles L. Edelstein
Download or read book Biomarkers of Kidney Disease written by Charles L. Edelstein and published by Academic Press. This book was released on 2016-11-08 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine. Explores both the practical and conceptual steps performed in the discovery of biomarkers in kidney disease Presents a comprehensive account of newer biomarker discover strategies, such as metabolomics and proteomics, all illustrated by clear examples Offers clear translational presentations by the top basic and clinical researchers in each specific renal disease, including AKI, transplantation, cancer, CKD, PKD, diabetic nephropathy, preeclampsia, and glomerular disease
Book Synopsis Kidney Transplantation by : Peter J. Morris
Download or read book Kidney Transplantation written by Peter J. Morris and published by W.B. Saunders Company. This book was released on 1984 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fifth edition of KIDNEY TRANSPLANTATION remains the most comprehensive and definitive text on all aspects of renal transplantation as well as the psychological and ethical issues involved. Almost every chapter has been revised or rewritten by new authors, to incorporate the most essential and up-to-date information.
Book Synopsis Biomarkers in Renal Disease by : Mitchell H. Rosner
Download or read book Biomarkers in Renal Disease written by Mitchell H. Rosner and published by Nova Publishers. This book was released on 2008 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in long-term improvement and outcomes of patients with kidney disease will require the use of novel biomarkers to identify patients at high risk for kidney disease and to diagnose kidney disease early for effective treatment. A biomarker is a substance found in the blood, body fluids or tissues that provides a measure of normal biological or pathological processes or response to pharmacological compounds or drugs. There are a wide variety of biomarkers including but not limited to mRNA, proteins and peptides, and lipid molecules. In AKI, important pathophysiological processes such as inflammation, apoptotic and necrotic cell death and, tubule regeneration may be reflected in blood or urine. An array of candidate markers along with clinical information in long-term clinical studies with appropriate analytical methodologies will likely provide prognostic information. Despite well-known limitations, currently the most widely used biomarkers for the early diagnosis of CKD and AKI are proteinuria, serum creatinine and blood urea nitrogen. Most clinicians are aware that serum creatinine and blood urea nitrogen are poor biomarkers due to inherent characteristics of these molecules and handling by the kidney. Creatinine is secreted and urea nitrogen is reabsorbed by the renal tubules. Many endogenous substances interfere in the assay for creatinine. Serum creatinine and urea appear late after acute kidney injury and the serum levels in part depend on the generation (large or small body mass). Acute kidney injury is a non steady state condition thus serum creatinine and urea nitrogen will lag behind kidney injury. For these reasons new biomarkers are imperative. With knowledge of these limitations in use of current biomarkers and the lack of progress in reducing the mortality and morbidity from kidney disease, there has been a great surge of interest in identifying novel biomarkers with a particular emphasis on the early diagnosis of kidney disease. A variety of methods have been employed including transcriptomics, proteomics, gene arrays and lipidomics. Currently, candidate biomarkers have been found in different disorders and have been tested in humans and many candidate biomarkers have yet to be identified. Most studies to date are preliminary and require validation in large multicentre studies followed by commercial assay development validation and testing. This new book outlines the rapid advances made in the field of biomarker development for kidney disease in which a variety of novel molecules have been identified and studied in humans.
Book Synopsis Utility of Urinary Biomarkers in Kidney Transplant Function Assessment by : Alina Kępka
Download or read book Utility of Urinary Biomarkers in Kidney Transplant Function Assessment written by Alina Kępka and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Utility of Urinary Biomarkers in Kidney Transplant Function Assessment.
Book Synopsis New Pipeline of Immunoregulatory Molecules and Biomarkers in Transplantation, An Issue of the Clinics in Laboratory Medicine by : Indira Guleria
Download or read book New Pipeline of Immunoregulatory Molecules and Biomarkers in Transplantation, An Issue of the Clinics in Laboratory Medicine written by Indira Guleria and published by Elsevier Health Sciences. This book was released on 2019-02-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine, guest edited by Dr. Indira Guleria, will focus on New Pipeline of Immunoregulatory Molecules and Biomarkers in Transplantation. Topics include, but are not limited to, T Regulatory cells in Stem cells and Solid organ transplantation, Genetic Polymorphism in Cytokines and Costimulatory Molecules in Stem Cell and Solid Organ Transplantation, microRNAs and Transplantation, Role of B Regulatory Cells in Transplant Tolerance, Complement Activation, Biomarkers in Stem Cell Transplantation, Biomarkers of Transplant Tolerance at the Fetomaternal Interface, Signaling molecules in Transplantation and Post-Transplantation Cancer, Donor specific HLA antibodies as Biomarkers of Transplant Rejection, Novel Targets of Immunosuppression in Transplantation, Nanotechnology and Immune therapies in Transplantation, Role of Costimulatory Pathways in Transplant Tolerance, and Microbiota and Immune system and Implications.
Book Synopsis Current Perspectives in Kidney Diseases by : G. La Manna
Download or read book Current Perspectives in Kidney Diseases written by G. La Manna and published by Karger Medical and Scientific Publishers. This book was released on 2017-05-23 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: After years of stagnation, much has been happening in the diagnosis and treatment of kidney diseases. This book contains a comprehensive review of the main developments in AKI, CKD, hemodialysis and kidney transplantation. The section on AKI deals with the key innovations in extracorporeal technologies. The section on nephrology and CKD concentrates on mineral metabolism alterations, restenosis in hemodialytic fistulas, mycophenolate mofetil as an alternative treatment for IgA nephropathy, and the genetics and progression of autosomal dominant polycystic kidney disease. The part on hemodialysis includes contributions on expanded hemodialysis, potassium profiling and home hemodialysis. Chapters on the treatment of acute antibody-mediated rejection after transplantation, pathogenesis and therapy of chronic allograft injury, and non-invasive surrogate biomarkers of acute rejection round out the subjects covered. Due to the wide variety of topics included in each section, this book is not only of interest to nephrologists, but also to professionals from related fields.
Book Synopsis Current Issues and Future Direction in Kidney Transplantation by : Thomas Rath
Download or read book Current Issues and Future Direction in Kidney Transplantation written by Thomas Rath and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: The here presented book covers different areas of clinical and scientific interest, reaching from donor evaluation to newest methods in immunological diagnostics. But also aspects of daily care of transplant recipients can be found in the carefully selected chapters. Everything driven by the aim to improve the care for all of our transplanted patients.
Book Synopsis The Role and Clinical Utility of Acute Kidney Injury Biomarkers in the Setting of Renal Transplantation by : Melanie Field
Download or read book The Role and Clinical Utility of Acute Kidney Injury Biomarkers in the Setting of Renal Transplantation written by Melanie Field and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chronic Graft Versus Host Disease by : Georgia B. Vogelsang
Download or read book Chronic Graft Versus Host Disease written by Georgia B. Vogelsang and published by Cambridge University Press. This book was released on 2009-04-20 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant.
Book Synopsis Monitoring of Renal Transplant Patients by Use of Complement Factors, Kidney-specific Cell-free DNA, Torque Teno Virus, and HLA Epitope Matching by : Ann-Maria Gramkow
Download or read book Monitoring of Renal Transplant Patients by Use of Complement Factors, Kidney-specific Cell-free DNA, Torque Teno Virus, and HLA Epitope Matching written by Ann-Maria Gramkow and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis National Kidney Foundation Primer on Kidney Diseases by : Scott J. Gilbert
Download or read book National Kidney Foundation Primer on Kidney Diseases written by Scott J. Gilbert and published by Elsevier Health Sciences. This book was released on 2014 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by (work): Primer on kidney diseases. 5th ed. c2009.
Book Synopsis Transplant Pathology by : Peter C. Kolbeck
Download or read book Transplant Pathology written by Peter C. Kolbeck and published by American Society of Clinical Pathologists Press. This book was released on 1994 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes by : J.A. Kellum
Download or read book ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes written by J.A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2013-05-14 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk.Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.
Book Synopsis Advances in the diagnosis and treatment in kidney transplantation, Volume II by : Kathrin Eller
Download or read book Advances in the diagnosis and treatment in kidney transplantation, Volume II written by Kathrin Eller and published by Frontiers Media SA. This book was released on 2023-01-30 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:
