Biology Of Brain Disorders

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Biology of Brain Disorders

Author : Daniela Tropea
Publisher : Frontiers Media SA
ISBN 13 : 2889453804
Total Pages : 586 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Biology of Brain Disorders by : Daniela Tropea

Download or read book Biology of Brain Disorders written by Daniela Tropea and published by Frontiers Media SA. This book was released on 2018-01-31 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention. Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking account of underlying molecular, cellular and systems biology underlying brain function will play an important role in the classification of brain disorders in future. In this Research Topic, the latest advances in our understanding of biological mechanisms across different brain disorders are presented. The areas covered include developments in neurogenetics, epigenetics, plasticity, glial cell biology, neuroimmune interactions and new technologies associated with the study of brain function. Examples of how understanding of biological mechanisms are translating into research strategies that aim to advance diagnoses and treatment of brain disorders are discussed.

Neurobiology of Brain Disorders

Author : Michael J. Zigmond
Publisher : Elsevier
ISBN 13 : 0123982804
Total Pages : 823 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Neurobiology of Brain Disorders by : Michael J. Zigmond

Download or read book Neurobiology of Brain Disorders written by Michael J. Zigmond and published by Elsevier. This book was released on 2014-12-03 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Biology of Brain Disorders

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Biology of Brain Disorders by :

Download or read book Biology of Brain Disorders written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention.Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking account of underlying molecular, cellular and systems biology underlying brain function will play an important role in the classification of brain disorders in future.In this Research Topic, the latest advances in our understanding of biological mechanisms across different brain disorders are presented. The areas covered include developments in neurogenetics, epigenetics, plasticity, glial cell biology, neuroimmune interactions and new technologies associated with the study of brain function. Examples of how understanding of biological mechanisms are translating into research strategies that aim to advance diagnoses and treatment of brain disorders are discussed.

Neurobiology of Brain Disorders

Author : Michael J. Zigmond
Publisher : Academic Press
ISBN 13 : 0323898254
Total Pages : 1136 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Neurobiology of Brain Disorders by : Michael J. Zigmond

Download or read book Neurobiology of Brain Disorders written by Michael J. Zigmond and published by Academic Press. This book was released on 2022-05-20 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function. Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more. Links basic, translational and clinical research on disorders of the nervous system Covers a vast array of neurological and psychiatric disorders, including Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson's, Huntington's, Alzheimer's, OCD, PTSD, schizophrenia, depression and pain Features new chapters on the effects of aging and isolation on brain health Expands coverage on disorders, including new chapters on fibromyalgia, chronic fatigue, and restless legs syndrome Features in-text summary points, special feature boxes and research questions

Biology of Brain Disorders – Cellular substrates for disrupted synaptic function and experience-dependent plasticity

Author : Daniela Tropea
Publisher : Frontiers Media SA
ISBN 13 : 2832500722
Total Pages : 202 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Biology of Brain Disorders – Cellular substrates for disrupted synaptic function and experience-dependent plasticity by : Daniela Tropea

Download or read book Biology of Brain Disorders – Cellular substrates for disrupted synaptic function and experience-dependent plasticity written by Daniela Tropea and published by Frontiers Media SA. This book was released on 2022-09-26 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biology of Brain Dysfunction

Author : Gerald E. Gaull
Publisher : Springer Science & Business Media
ISBN 13 : 1468426737
Total Pages : 493 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Biology of Brain Dysfunction by : Gerald E. Gaull

Download or read book Biology of Brain Dysfunction written by Gerald E. Gaull and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growth of neurochemistry. molecular biology, and biochemical genetics has led to a burgeoning of new information relevant to the pathogenesis of brain dysfunction. This explosion of exciting new information is crying out for collation and meaningful synthesis. In its totality, it defies systematic summa tion, and, of course, no one author can cope. Thus invitations for contributions were given to various experts in areas which are under active investigation, of current neurological interest, and pregnant. Although this project is relatively comprehensive, by dint of size. other topics might have been included; the selection was solely my responsibility. I believe systematic summation a virtual impossibility-indeed, hardly worth the effort. The attempt to assemble all of the sections involved in a large treatise with multiple authors inevitably results in untoward delays due to the difference in the rate at which various authors work. Therefore, the following strategy has been adopted: multiple small volumes and a relatively flexible format, with publication in order of receipt and as soon as enough chapters are assembled to make publication practical and economical. In this way, the time lag between the ideas and their emergence in print is the shortest.

Molecular Biology of Neuropsychiatric Disorders

Author : Dieter B. Wildenauer
Publisher : Springer Science & Business Media
ISBN 13 : 3540853839
Total Pages : 303 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Molecular Biology of Neuropsychiatric Disorders by : Dieter B. Wildenauer

Download or read book Molecular Biology of Neuropsychiatric Disorders written by Dieter B. Wildenauer and published by Springer Science & Business Media. This book was released on 2008-11-28 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is generally accepted that neuropsychiatric disorders have a biological basis. Pathological changes leading to illness have been confirmed for Alzheimer’s (amyloid plaques) and Parkinson’s disease (loss of dopaminergic transmission) and are the foundation for studies on the molecular biology of these disorders. For other neuropsychiatric disorders, in particular for schizophrenic and affective disorders, molecular causes appear to be more complex and therefore remain hypothetical, despite decades of research. Changes in a number of neuronal pathways and structures have been reported to be associated with these disorders and are currently under extensive investigation. The present volume reviews recent knowledge with emphasis on ongoing research findings. Current hypotheses based on these findings are described and discussed.

Stem Cell-Based Neural Model Systems for Brain Disorders

Author : Yu-Wen Alvin Huang
Publisher : Springer Nature
ISBN 13 : 1071632876
Total Pages : 290 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Stem Cell-Based Neural Model Systems for Brain Disorders by : Yu-Wen Alvin Huang

Download or read book Stem Cell-Based Neural Model Systems for Brain Disorders written by Yu-Wen Alvin Huang and published by Springer Nature. This book was released on 2023-06-10 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents validated and well-adapted procedures involving humanized and/or stem cell-based neural model systems that have proven helpful in better understanding the essential brain functions involved in the pathogenesis of brain disorders. The book explores the generation of multiple neural cell types in 2D and 3D as well as cutting-edge techniques to assay neural function. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Stem Cell-Based Neural Model Systems for Brain Disorders serves as an essential resource for researchers and students in neuroscience, stem cell biology, and related fields.

Biology of Brain Dysfunction

Author : Gerald E. Gaull
Publisher : Springer Science & Business Media
ISBN 13 : 1468426702
Total Pages : 431 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Biology of Brain Dysfunction by : Gerald E. Gaull

Download or read book Biology of Brain Dysfunction written by Gerald E. Gaull and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growth of neurochemistry, molecular biology, and biochemical genetics has led to a burgeoning of new information relevant to the pathogenesis of brain dysfunction. This explosion of exciting new information is crying out for collation and meaningful synthesis. In its totality, it defies systematic summa tion, and, of course, no one author can cope. Thus invitations for contributions were given to various experts in areas which are under active investigation, of current neurological interest, and pregnant. Although this project is relatively comprehensive, by dint of size, other topics might have been included; the selection was solely my responsibility. I believe systematic summation a virtual impossibility-indeed, hardly worth the effort. The attempt to assemble all of the sections involved in a large treatise with mUltiple authors inevitably results in untoward delays due to the difference in the rate at which various authors work. Therefore, the following strategy has been adopted: multiple small volumes and a relatively flexible format, with publication in order of receipt and as soon as enough chapters are assembled to make publication practical and economical. In this way, the time lag between the ideas and their emergence in print is the shortest.

Biology of Brain Dysfunction

Author : Gerald E. Gaull
Publisher : Springer
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biology of Brain Dysfunction by : Gerald E. Gaull

Download or read book Biology of Brain Dysfunction written by Gerald E. Gaull and published by Springer. This book was released on 1973 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growth of neurochemistry, molecular biology, and biochemical genetics has led to a burgeoning of new information relevant to the pathogenesis of brain dysfunction. This explosion of exciting new information is crying out for collation and meaningful synthesis. In its totality, it defies systematic summa tion, and, of course, no one author can cope. Thus invitations for contributions were given to various experts in areas which are under active investigation, of current neurological interest, and pregnant. Although this project is relatively comprehensive, by dint of size, other topics might have been included; the selection was solely my responsibility. I believe systematic summation a virtual impossibility-indeed, hardly worth the effort. The attempt to assemble all of the sections involved in a large treatise with multiple authors inevitably results in untoward delays due to the difference in the rate at which various authors work. Therefore, the following strategy has been adopted: multiple small volumes and a relatively flexible format, with publication in order of receipt and as soon as enough chapters are assembled to make publication practical and economical. In this way, the time lag between the ideas and their emergence in print is the shortest.

Neurobiology For Dummies

Author : Frank Amthor
Publisher : John Wiley & Sons
ISBN 13 : 1118691466
Total Pages : 411 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Neurobiology For Dummies by : Frank Amthor

Download or read book Neurobiology For Dummies written by Frank Amthor and published by John Wiley & Sons. This book was released on 2014-03-10 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: The approachable, comprehensive guide to neurobiology Neurobiology rolls the anatomy, physiology, and pathology of the nervous system into one complex area of study. Neurobiology For Dummies breaks down the specifics of the topic in a fun, easy-to-understand manner. The book is perfect for students in a variety of scientific fields ranging from neuroscience and biology to pharmacology, health science, and more. With a complete overview of the molecular and cellular mechanisms of the nervous system, this complete resource makes short work of the ins and outs of neurobiology so you can understand the details quickly. Dive into this fascinating guide to an even more fascinating subject, which takes a step-by-step approach that naturally builds an understanding of how the nervous system ties into the very essence of human beings, and what that means for those working and studying in the field of neuroscience. The book includes a complete introduction to the subject of neurobiology. Gives you an overview of the human nervous system, along with a discussion of how it's similar to that of other animals Discusses various neurological disorders, such as strokes, Alzheimer's disease, Parkinson's disease, and schizophrenia Leads you through a point-by-point approach to describe the science of perception, including how we think, learn, and remember Neurobiology For Dummies is your key to mastering this complex topic, and will propel you to a greater understanding that can form the basis of your academic and career success.

Endogenous Stem Cell-Based Brain Remodeling in Mammals

Author : Marie-Pierre Junier
Publisher : Springer Science & Business Media
ISBN 13 : 1489973990
Total Pages : 234 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Endogenous Stem Cell-Based Brain Remodeling in Mammals by : Marie-Pierre Junier

Download or read book Endogenous Stem Cell-Based Brain Remodeling in Mammals written by Marie-Pierre Junier and published by Springer Science & Business Media. This book was released on 2014-02-08 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text highlights the endogenous regenerative potential of the central nervous system in neonates and juveniles and discusses possible ways it might be manipulated for medical purposes. The first section provides a descriptive summary of the salient steps of human brain development with a discussion of comparisons with other mammalian brains. It also provides a historical perspective on our understanding of ongoing brain development throughout the lifespan and serve to introduce the concept of brain plasticity following injury. The second part is devoted to the endogenous reparative potential of the brain, including its limitations, and articles focusing on defined pathologies (e.g. anoxia/hypoxia, epilepsy, traumatic brain injury and stress) in animal models and in humans pinpoint eventual ways these pathologies might be manipulated. The third and final focuses on the "dark side" of stem cells for brain repair or of the manipulation of spontaneous adaptive events after injury (e.g. genomic instability, sensitization to cancerous transformation and defective neural networks).

Mitochondria and Brain Disorders

Author : Stavros Baloyannis
Publisher : BoD – Books on Demand
ISBN 13 : 1789855314
Total Pages : 125 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Mitochondria and Brain Disorders by : Stavros Baloyannis

Download or read book Mitochondria and Brain Disorders written by Stavros Baloyannis and published by BoD – Books on Demand. This book was released on 2020-03-11 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.

Transgenic and Mutant Tools to Model Brain Disorders

Author : Allan V. Kalueff
Publisher : Humana
ISBN 13 : 9781493961450
Total Pages : 246 pages
Book Rating : 4.9/5 (614 download)

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Book Synopsis Transgenic and Mutant Tools to Model Brain Disorders by : Allan V. Kalueff

Download or read book Transgenic and Mutant Tools to Model Brain Disorders written by Allan V. Kalueff and published by Humana. This book was released on 2016-08-23 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the presence of genetically modified animal models in research laboratories has multiplied, the role of genetic factors in the pathogenesis of brain disorders has become particularly important. The refinement of molecular genetic methods has continued to broaden our understanding of the genetic factors associated with a variety of disorders. In "Transgenic and Mutant Tools to Model Brain Disorders", leading scientists specializing in this field contribute a timely collection of recent advances featuring a vast array of topics in order to contribute to the diverse approaches taken toward the evaluation of genetically modified models in biomedical research. Opening with several chapters covering general aspects of genetically modified animal models, the book then continues with detailed chapters on models of specific human brain disorders, including OCD, Rett Syndrome, anxiety disorders, depression, and schizophrenia. As a volume in the successful NeuromethodsTM series, the chapters provide authoritative reviews covering the most commonly used approaches in the field. Cutting-edge and concise, "Transgenic and Mutant Tools to Model Brain Disorders" offers a comprehensive and descriptive overview on a variety of topics in neuroscience and biological psychiatry.

Discovering the Brain

Author : National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 0309045290
Total Pages : 195 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Discovering the Brain by : National Academy of Sciences

Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Biology of Brain Dysfunction

Author : 3Island Press
Publisher :
ISBN 13 : 9781468426687
Total Pages : 424 pages
Book Rating : 4.4/5 (266 download)

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Book Synopsis Biology of Brain Dysfunction by : 3Island Press

Download or read book Biology of Brain Dysfunction written by 3Island Press and published by . This book was released on 1973-01-01 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Brain Aging and Therapeutic Interventions

Author : Mahendra K. Thakur
Publisher : Springer Science & Business Media
ISBN 13 : 9400752377
Total Pages : 300 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Brain Aging and Therapeutic Interventions by : Mahendra K. Thakur

Download or read book Brain Aging and Therapeutic Interventions written by Mahendra K. Thakur and published by Springer Science & Business Media. This book was released on 2012-12-11 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together most up-to-date information on different aspects of brain aging and on the strategies for intervention and therapy of age-related brain disorders. It includes 18 chapters by leading researchers, and each chapter is a comprehensive and critical review of the topic in question, discusses the current scenario and focuses on future perspectives. The target readership is the undergraduate and graduate students in the universities, in medical and nursing colleges, along with the post-graduate researchers and practicing clinicians who would like to know about the latest developments in the field of neurodegenerative disorders and their therapeutic interventions. This book will be of much interest to pharmaceutical, nutrition and healthcare industry for an easy access to accurate and reliable information in the field of aging research and intervention.