Biointegration Of Medical Implant Materials

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Biointegration of Medical Implant Materials

Author : Chandra P. Sharma
Publisher : Elsevier
ISBN 13 : 1845699807
Total Pages : 429 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Biointegration of Medical Implant Materials by : Chandra P. Sharma

Download or read book Biointegration of Medical Implant Materials written by Chandra P. Sharma and published by Elsevier. This book was released on 2010-07-13 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue.Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering.With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. - Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration - Discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction - Reviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery

Biointegration of Medical Implant Materials

Author : Chandra P. Sharma
Publisher : Woodhead Publishing
ISBN 13 : 0081026811
Total Pages : 510 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Biointegration of Medical Implant Materials by : Chandra P. Sharma

Download or read book Biointegration of Medical Implant Materials written by Chandra P. Sharma and published by Woodhead Publishing. This book was released on 2019-09-17 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biointegration of Medical Implant Materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. New sections discuss soft tissue integration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. Other sections review tissue regeneration, inorganic nanoparticles for targeted drug delivery, alginate based drug delivery devices, and design considerations, with coverage of the biocompatibility of materials and their relevance to drug delivery and tissue engineering. With its distinguished editor and team of international contributors, this book is ideal for medical materials scientists and engineers in industry and academia. Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration Discusses soft tissue biointegration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction Includes new information on a variety of tissue regeneration techniques and applications

Bio-Implant Interface

Author : J.E. Ellingsen
Publisher : CRC Press
ISBN 13 : 1135508216
Total Pages : 593 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Bio-Implant Interface by : J.E. Ellingsen

Download or read book Bio-Implant Interface written by J.E. Ellingsen and published by CRC Press. This book was released on 2003-04-29 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achieving good clinical outcomes with implanted biomaterials depends upon achieving optimal function, both mechanical and biological, which in turn depends upon integrating advances realized in biological science, material science, and tissue engineering. As these advances push back the frontiers of biomaterial medicine , the control and patterning

Bio-tribocorrosion in biomaterials and medical implants

Author : R.J.K. Wood
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128089881
Total Pages : 30 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Bio-tribocorrosion in biomaterials and medical implants by : R.J.K. Wood

Download or read book Bio-tribocorrosion in biomaterials and medical implants written by R.J.K. Wood and published by Elsevier Inc. Chapters. This book was released on 2013-09-30 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tribological performance of implant materials within the body where the pH can vary between 7.4 and 4.0, depending on whether the joint is infected or not, is extremely harsh and varies significantly from that experienced in other engineering environments. Three wear mechanisms that affect biomedical and, in particular, orthopaedic implants are regularly reported. These are adhesion, abrasion and fatigue. The wear mechanisms in biomedical implants, particularly hip joints, are reported to be a function of the following variables: type of materials used, contact stresses, lubricants and clearance, surface hardness and roughness, type of articulation due to motion, number of cycles, solution particle count and distribution, and tribocorrosion.

Bio-tribocorrosion in biomaterials and medical implants

Author : J.J. Ryu
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128089857
Total Pages : 25 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Bio-tribocorrosion in biomaterials and medical implants by : J.J. Ryu

Download or read book Bio-tribocorrosion in biomaterials and medical implants written by J.J. Ryu and published by Elsevier Inc. Chapters. This book was released on 2013-09-30 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter discusses synergistic damage mechanisms of modular implants due to mechanical stimulus and electrochemical dissolution. The influences of contact loads, plastic deformation, residual stresses, and environmental conditions are focused to illustrate mechanisms of damage and dissolution. Fretting corrosion is the most prevalent phenomenon that degrades the mechanical and chemical properties of implant materials. It has been explained as an alternating process of fracture and unstable growth of metal oxide film during fatigue contact motion in the corrosive environment. Stress-dependent electrochemical dissolution has also been identified as one of the key mechanisms governing surface degradation in fatigue contact and crevice corrosion of biomedical implants. This damage mechanism incorporates contact-induced residual stress development and stress-assisted dissolution. Understanding of the corrosion damage mechanism of metallic implants is very important in predicting the useful life of implants and optimizing the design of orthopedic implants.

Bio-Tribocorrosion in Biomaterials and Medical Implants

Author : Yu Yan
Publisher : Elsevier
ISBN 13 : 0857098608
Total Pages : 434 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Bio-Tribocorrosion in Biomaterials and Medical Implants by : Yu Yan

Download or read book Bio-Tribocorrosion in Biomaterials and Medical Implants written by Yu Yan and published by Elsevier. This book was released on 2013-09-30 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: During their service life, most biomaterials and medical implants are vulnerable to tribological damage. In addition, the environments in which they are placed are often corrosive. The combination of triobology, corrosion and the biological environment has been named ‘bio-tribocorrosion’. Understanding this complex phenomenon is critical to improving the design and service life of medical implants. This important book reviews recent key research in this area. After an introduction to the topography of bio-tribocorrosion, Part one discusses different types of tribocorrosion including fatigue-corrosion, fretting-corrosion, wear-corrosion and abrasion-corrosion. The book also discusses the prediction of wear in medical devices. Part two looks at biological effects on tribocorrosion processes, including how proteins interact with material surfaces and the evolution of surface changes due to bio-tribocorrosion resulting from biofilms and passive films. Part three reviews the issue of bio-tribocorrosion in clinical practice, including dental applications and joint replacement as well the use of coatings and test methods for bio-tribocorrosion. With its international team of contributors, Bio-tribocorrosion in biomaterials and medical implants is a standard reference for those researching and developing medical devices as well as clinicians in such areas as dentistry and orthopaedic surgery. Reviews recent research in bio-tribocorrosion and its role in improving the design and service life of medical implants Discusses types of bio-tribocorrosion including fatigue and wear corrosion Examines biological effects on bio-tribocorrosion processes including interaction of proteins with metal surfaces

Bio-tribocorrosion in biomaterials and medical implants

Author : P. Silva-Bermudez
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128089946
Total Pages : 75 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Bio-tribocorrosion in biomaterials and medical implants by : P. Silva-Bermudez

Download or read book Bio-tribocorrosion in biomaterials and medical implants written by P. Silva-Bermudez and published by Elsevier Inc. Chapters. This book was released on 2013-09-30 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this chapter, a general overview of current dental implants is presented, identifying weak points where improvements can be made. Particular importance is given to the surface properties of materials susceptible to modifications for improving the biological response for the specific application. Then, the concepts and techniques relevant for the evaluation of the physico-chemical properties and the protein adsorption, biocompatibility, bioactivity and biofilm formation are described. The chapter describes a particular method to modify the chemical and physical properties of materials, known as magnetron sputtering. Finally, an example using Nb2O5 coatings is presented, where also corrosion resistance and adhesion results are included.

Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach

Author : Frederick Silver
Publisher : Springer Science & Business Media
ISBN 13 : 9780412412608
Total Pages : 318 pages
Book Rating : 4.4/5 (126 download)

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Book Synopsis Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach by : Frederick Silver

Download or read book Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach written by Frederick Silver and published by Springer Science & Business Media. This book was released on 1993-11-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.

Biomaterials

Author : Sujata V. Bhat
Publisher : Alpha Science Int'l Ltd.
ISBN 13 : 9781842652077
Total Pages : 298 pages
Book Rating : 4.6/5 (52 download)

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Book Synopsis Biomaterials by : Sujata V. Bhat

Download or read book Biomaterials written by Sujata V. Bhat and published by Alpha Science Int'l Ltd.. This book was released on 2005 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: As biomaterials are used in medical devices, providing needs in such diverse surgical disciplines as ophthalmology, cardiology, neuromuscular surgery, orthopedics, dentistry etc., they must have intimate contact with patient's tissue or body fluid providing a real physical interface, which restricts developments most seriously. This book is written for those who would like to advance their knowledge of biomaterials. The subject matter of the book is divided into twelve chapters dealing with structure and relationship of biological and man made biomaterials. The application of these materials for various medical devices and recent developments in tissue engineering has also covered.

Biomedical Implants

Author : Ravi K. Dwivedi
Publisher : CRC Press
ISBN 13 : 1003851096
Total Pages : 265 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Biomedical Implants by : Ravi K. Dwivedi

Download or read book Biomedical Implants written by Ravi K. Dwivedi and published by CRC Press. This book was released on 2024-02-14 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the development of implants, from the selection of materials to the outcome of the process. It covers various steps, including biocompatible material, synthesis, and characterization, compatibility and limitations of materials, specific implants, and finite element analysis of medical implants. It also presents a comparison between predictions and experimental results by studying real-world problems and addresses the issue of sustainability in implant manufacturing, process modeling, and optimization in additive manufacturing supported by case studies. Features: • Covers the development of implants from the selection of material to the suitable process of manufacturing technologies. • Includes biocompatible material, synthesis, characterization, compatibility, and limitations of materials. • Reviews biofabrication in terms of artificial organs and soft tissues. • Discusses implant manufacturing, including additive and micro-manufacturing and failure analysis through case studies. • Addresses the issue of sustainability in implant manufacturing. This book is intended for researchers and graduate students specializing in mechanical, biomedical, healthcare engineering, biomaterials, and additive manufacturing.

Biomaterials in Translational Medicine

Author : Lei Yang
Publisher : Academic Press
ISBN 13 : 012813478X
Total Pages : 364 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biomaterials in Translational Medicine by : Lei Yang

Download or read book Biomaterials in Translational Medicine written by Lei Yang and published by Academic Press. This book was released on 2018-11-30 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. - Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine - Includes the translational or commercialization status of these new biomaterials - Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine - Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials

Biomaterials

Author : Roderic S. Lakes
Publisher : Springer Science & Business Media
ISBN 13 : 1475721560
Total Pages : 400 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Biomaterials by : Roderic S. Lakes

Download or read book Biomaterials written by Roderic S. Lakes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended as a general introduction to the uses of artificial materials in the human body for the purposes of aiding healing, correcting deformities, and restoring lost function. It is an outgrowth of an undergraduate course for senior students in biomedical engineering, and it is offered as a text to be used in such courses. Topics include biocompatibility, techniques to minimize cor rosion or other degradation of implant materials, principles of materials science as it relates to the use of materials in the body, and specific uses of materials in various tissues and organs. It is expected that the student will have successively completed elementary courses in the mechanics of deformable bodies and in anatomy and physiology, and preferably also an introductory course in materials science prior to undertaking a course in biomaterials. Many quantitative examples are included as exercises for the engineering student. We recognize that many of these involve unrealistic simplifications and are limited to simple mechanical or chemical aspects of the implant problem. We offer as an apology the fact that biomaterials engineering is still to a great extent an empirical discipline that is complicated by many unknowns associated with the human body. In recognition of that fact, we have endeavored to describe both the successes and the failures in the use of materials in the human body. Also included are many photographs and illustrations of implants and devices as an aid to visualization.

Handbook Of Biomaterials Evaluation

Author : Andreas F von Recum
Publisher : CRC Press
ISBN 13 : 9781560324799
Total Pages : 944 pages
Book Rating : 4.3/5 (247 download)

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Book Synopsis Handbook Of Biomaterials Evaluation by : Andreas F von Recum

Download or read book Handbook Of Biomaterials Evaluation written by Andreas F von Recum and published by CRC Press. This book was released on 1998-12-18 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook addresses the needs of those who are involved in inventing, developing, and testing implants and are concerned about the interactions between biomaterial and body tissue. The authors explore the physical, chemical, mechanical and regulatory considerations of synthetic materials used in surgical and implant procedures, and how these factors impact the latest developments and new approaches. This updated edition provides the biomaterials professional with necessary information on a range of issues, including bulk characterization, surface evaluations, toxicological evaluations, in vitro methods for safety evaluation, methods for evaluating materials in special applications, surgical considerations, systems implantology, soft and hard tissue history, regulatory aspects, and clinical trials.

Biomaterials and Implant Biocompatibility

Author : Anişoara Cîmpean
Publisher : MDPI
ISBN 13 : 3039282166
Total Pages : 420 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Biomaterials and Implant Biocompatibility by : Anişoara Cîmpean

Download or read book Biomaterials and Implant Biocompatibility written by Anişoara Cîmpean and published by MDPI. This book was released on 2020-03-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific advances in life sciences and engineering are constantly challenging, expanding, and redefining concepts related to the biocompatibility and safety of medical devices. New biomaterials, new products, and new testing regimes are being introduced to scientific research practices. In order to provide clinically predictive results and to ensure a high benefit–risk ratio for patients, we need to optimize material and implant characteristics, and to adapt performance and safety evaluation practices for these innovative medical devices. Various characteristics related to materials and implant development such as raw materials composition, implant surface morphology, design, geometry, porosity, and mechanical properties need to be thoroughly characterized before evaluating the biological performance of implants. Furthermore, with the increase of regulatory demands, biological evaluation needs to ensure appropriate models and methods for each implant development stage. This book is a result of the Special Issue of Materials on "Biomaterials and Implant Biocompatibility”, which focused on the recent progress in development, material testing, and the biocompatibility and bioactivity evaluation of various materials including, but not limited to, bioceramics, biopolymers, biometals, composite materials, biomimetic materials, hybrid biomaterials, and drug/device combinations for implants and prostheses with medical applications spanning from soft to hard tissue regeneration. The book covers aspects ranging from investigations into material characterization to in vitro and in vivo testing for the assessment of biological performance of advanced, novel biomaterials and implants.

Functional Bio-based Materials for Regenerative Medicine From Bench to Bedside (Part 2)

Author : Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus
Publisher : Bentham Science Publishers
ISBN 13 : 9815179349
Total Pages : 309 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Functional Bio-based Materials for Regenerative Medicine From Bench to Bedside (Part 2) by : Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus

Download or read book Functional Bio-based Materials for Regenerative Medicine From Bench to Bedside (Part 2) written by Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus and published by Bentham Science Publishers. This book was released on 2024-02-02 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing. Topics in the book include: - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix. - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential. - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration. - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use Part 2 covers advanced materials and techniques used in tissue engineering. Topics focus on advanced composite materials for 3D scaffolds and the repair of tissues in different organs such as the heart, cornea, bone and ligaments. Materials highlighted in this part include polyamide composites, electrospun nanofibers, and different bio-based hydrogels. Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Biological Performance of Materials

Author : Jonathan Black
Publisher : CRC Press
ISBN 13 : 9780849339592
Total Pages : 526 pages
Book Rating : 4.3/5 (395 download)

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Book Synopsis Biological Performance of Materials by : Jonathan Black

Download or read book Biological Performance of Materials written by Jonathan Black and published by CRC Press. This book was released on 2005-12-20 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioengineers need a thorough grounding in biocompatibility - the biological performance of materials. Until now, there were no publications suitable for a neophyte in the field; prior publications were either not comprehensive or focused on rather narrow interests. Drawing on the author's 35 years of experience as a teacher, researcher, and consultant in biomaterials science and engineering (BSE), Biological Performance of Materials: Fundamentals of Biocompatibility, Fourth Edition focuses primarily on principles of biological performance at a relatively fundamental level, analyzing interactions between living organisms and nonliving materials used in medical devices - the subject that sets BSE apart as a distinct field of investigation. Following an introductory section, the book is divided into three sections: the material response to biological systems, host response to biomaterials, and test methods for determining biological response in vitro as well as in animal models and clinical settings. Supplemental "Interparts" summarize the physical properties of commonly used metallic, polymeric, and ceramic biomaterials. They also provide a guide to understanding the clinical performance of implanted biomaterials.

Laser Surface Treatment of Bio-Implant Materials

Author : Liang Hao
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Laser Surface Treatment of Bio-Implant Materials by : Liang Hao

Download or read book Laser Surface Treatment of Bio-Implant Materials written by Liang Hao and published by John Wiley & Sons. This book was released on 2005-11-18 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biomaterials technology industry is already well established in the western world and is growing rapidly within Asian Pacific nations. It is often described as the ‘next electronics industry’, whilst the laser is described as a ‘solution looking for a problem’. This book describes the use of the laser to solve a troublesome and costly problem in a rapidly growing global industry. The authors have spent many years conducting research using laser materials processing and wettability characteristics and have perfected a technique to improve the bio-compatibility of various bone-implant materials using laser irradiation. They have made pioneering discoveries on the subject and established some generic theories and principals that will have a wide range of applications in the biomaterials field. Introduces inter-disciplinary research work covering laser materials processing and surface modification of biomaterials for enhanced compatibility. Includes highly scientific and novel research material. Serves both as a practitioner guide and a reference book. Covers an exciting and rapidly developing area of technology that is of keen interest to engineers and clinicians alike. Laser Surface Treatment of Bio-Implant Materials is rare in providing a reference source that describes specifically a mechanical engineering solution to a biotechnology problem. It serves as both a practitioner guide and a medium to high-level reference text book, and as such is a reference source for the engineer practising or looking to move into the biomaterials field, undergraduate and post graduate students and those conducting bio-related research in either academia or industry. It will prove useful to mechanical engineers, biotechnologists, biomechanical engineers, metallurgists, clinicians and even surgeons.