Biofilm Associated Antimicrobial Resistance and Its Recovery

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Author :
Publisher : CRC Press
ISBN 13 : 1003801439
Total Pages : 391 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Biofilm Associated Antimicrobial Resistance and Its Recovery by : Dibyajit Lahiri

Download or read book Biofilm Associated Antimicrobial Resistance and Its Recovery written by Dibyajit Lahiri and published by CRC Press. This book was released on 2023-12-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biofilm is a collection of microbial cells that have adhered to biotic surfaces such as plant cuticles or animal epithelia, as well as abiotic surfaces such as rocky substratum or catheter exteriors. The life cycle of a microorganism includes the fundamental process of biofilm formation for survival in diverse and harsh environments since it is a protected mode of growth allowing colonisation of new habitats by dispersal of microbes from the microbial clusters. The biofilm bound microorganisms remain embedded in an extracellular polymeric matrix that protects the indwelling cells from surfactants, biocides, several invaders like protozoans, and defences offered by the hosts like phagocytic cells. The biofilm bound recalcitrant microbes induce chronic and nosocomial diseases, posing a serious threat to public health. It has been observed that various antimicrobial drugs are able to successfully remove the planktonic (freely suspended) states of microbes as compared to the sessile (substrate-bound) forms, thus resulting in the development of antimicrobial resistance. Modern pharmacological strategies targeting the biofilm matrix differ from the conventional methods of antibiotic usage. This includes the use of natural compounds such as plant bioactive molecules, antimicrobial peptides, green synthesised nanoparticles, or secondary metabolites from other organisms that not only prevent the rise of antimicrobial resistance but are also safe for the host tissues. Biofilm Associated Antimicrobial Resistance and Its Recovery provides a detailed and systematic review of alternative pharmacological developments in the field of biofilm research. Features: A narrative overview of the mechanism of biofilm formation and its role in the emergence of antimicrobial resistance. Recent research in the development of antibiofilm remedies involving biogenic compounds. Advancements in biofilm detection methodologies with cutting-edge technologies. This book serves as a resource for researchers who need to understand and analyze the progression of events during microbial biofilm formation, as well as design safer methodologies for its successful eradication. It may also be used as a textbook for a graduate level course in microbiology or microbial biotechnology.

Biofilm Associated on Antimicrobial Resistance and Its Recovery

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Author :
Publisher :
ISBN 13 : 9781003281238
Total Pages : 0 pages
Book Rating : 4.2/5 (812 download)

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Book Synopsis Biofilm Associated on Antimicrobial Resistance and Its Recovery by : Rina Rani Ray

Download or read book Biofilm Associated on Antimicrobial Resistance and Its Recovery written by Rina Rani Ray and published by . This book was released on 2023-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A biofilm is a collection of microbial cells that have adhered to biotic surfaces such as plant cuticles or animal epithelia, as well as abiotic surfaces such as rocky substratum or catheter exteriors. The life cycle of microorganism includes the fundamental process of biofilm formation for survival in diverse and harsh environments since it is a protected mode of growth allowing colonisation of new habitats by dispersal of microbes from the microbial clusters. The biofilm bound microorganisms remain embedded in an extracellular polymeric matrix that protects the indwelling cells from surfactants, biocides, several invaders like protozoans, and defences offered by the hosts like phagocytic cells. The biofilm bound recalcitrant microbes induce chronic and nosocomial diseases, posing a serious threat to public health. It has been observed that various antimicrobial drugs are able to successfully remove the planktonic (freely suspended) states of microbes as compared to the sessile (substrate-bound) forms, thus resulting in the development of antimicrobial resistance. Modern pharmacological strategies targeting the biofilm matrix differ from the conventional methods of antibiotic usage. This includes the use of natural compounds such as plant bioactive molecules, antimicrobial peptides, green synthesised nanoparticles, or secondary metabolites from other organisms that not only prevent the rise of antimicrobial resistance but are also safe for the host tissues. The book titled "Biofilm Associated on Antimicrobial Resistance and Its Recovery" provides a detailed and systematic review of alternative pharmacological developments in the field of biofilm research. Features: A narrative overview of the mechanism of biofilm formation and its role in the emergence of antimicrobial resistance. Recent research in the development of antibiofilm remedies involving biogenic compounds. Advancements in the biofilm detection methodologies with the cutting-edge technologies. This book serves as a reference book for researchers who need to understand and analyze the progression of events during microbial biofilm formation, as well as design safer methodologies for its successful eradication. It may also be used as a textbook for a graduate level course in microbiology or microbial biotechnology"--

Microbial Biofilms

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Author :
Publisher : Elsevier
ISBN 13 : 0443192529
Total Pages : 290 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Microbial Biofilms by : Mukesh Kumar Yadav

Download or read book Microbial Biofilms written by Mukesh Kumar Yadav and published by Elsevier. This book was released on 2024-04-15 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health. Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.

Bacterial Biofilms

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Publisher : Springer Science & Business Media
ISBN 13 : 3540754180
Total Pages : 302 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Bacterial Biofilms by : Tony Romeo

Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Treating Infectious Diseases in a Microbial World

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Publisher : National Academies Press
ISBN 13 : 0309180686
Total Pages : 102 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Treating Infectious Diseases in a Microbial World by : National Research Council

Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Biofilm Infections

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Publisher : Springer
ISBN 13 : 9781489982285
Total Pages : 0 pages
Book Rating : 4.9/5 (822 download)

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Book Synopsis Biofilm Infections by : Thomas Bjarnsholt

Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

The Science and Applications of Synthetic and Systems Biology

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Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Antimicrobial Resistance

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1839624329
Total Pages : 210 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Antimicrobial Resistance by : Mihai Mares

Download or read book Antimicrobial Resistance written by Mihai Mares and published by BoD – Books on Demand. This book was released on 2021-03-03 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.

Gene Transfer in the Environment

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Author :
Publisher : McGraw-Hill Companies
ISBN 13 :
Total Pages : 458 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Gene Transfer in the Environment by : Stuart B. Levy

Download or read book Gene Transfer in the Environment written by Stuart B. Levy and published by McGraw-Hill Companies. This book was released on 1989 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Biofilms

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Author :
Publisher : Elsevier
ISBN 13 : 0443192537
Total Pages : 291 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Microbial Biofilms by : Mukesh Kumar Yadav

Download or read book Microbial Biofilms written by Mukesh Kumar Yadav and published by Elsevier. This book was released on 2024-04-15 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants. Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health. Fulfills the knowledge gap in biofilm study Focuses on new and emerging concepts in microbial biofilm research Highlights the various anti-biofilm strategies Provides concise, thorough and up-to-date information about the important role of microbial biofilms in human diseases

Extending the Cure

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Publisher : Routledge
ISBN 13 : 1136527605
Total Pages : 193 pages
Book Rating : 4.1/5 (365 download)

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Book Synopsis Extending the Cure by : Ramanan Laxminarayan

Download or read book Extending the Cure written by Ramanan Laxminarayan and published by Routledge. This book was released on 2010-09-30 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.

Antimicrobial Resistance

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Publisher :
ISBN 13 : 9789241564748
Total Pages : 232 pages
Book Rating : 4.5/5 (647 download)

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Book Synopsis Antimicrobial Resistance by : World Health Organization

Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

New Insights on Biofilm Antimicrobial Strategies

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Publisher : MDPI
ISBN 13 : 3036512217
Total Pages : 264 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis New Insights on Biofilm Antimicrobial Strategies by : Luís Melo

Download or read book New Insights on Biofilm Antimicrobial Strategies written by Luís Melo and published by MDPI. This book was released on 2021-08-17 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.

The Perfect Slime

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Publisher : IWA Publishing
ISBN 13 : 1780407416
Total Pages : 336 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis The Perfect Slime by : Hans-Curt Flemming

Download or read book The Perfect Slime written by Hans-Curt Flemming and published by IWA Publishing. This book was released on 2016-09-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?

Textbook of Diagnostic Microbiology - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323482120
Total Pages : 1088 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Textbook of Diagnostic Microbiology - E-Book by : Connie R. Mahon

Download or read book Textbook of Diagnostic Microbiology - E-Book written by Connie R. Mahon and published by Elsevier Health Sciences. This book was released on 2018-01-18 with total page 1088 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to develop the problem-solving skills necessary for success in the clinical setting! The Textbook of Diagnostic Microbiology, 6th Edition uses a reader-friendly "building-block" approach to the essentials of diagnostic microbiology. This updated edition has new content on viruses like Zika, an expanded molecular chapter, and the latest information on prevention, treatment modalities, and CDC guidelines. Updated photos offer clear examples of automated lab instruments, while case studies, review questions, and learning objectives present information in an easy-to-understand, accessible manner for students at every level. A building-block approach encourages you to use previously learned information to sharpen critical-thinking and problem-solving skills. Full-color design, with many full-color photomicrographs, prepares you for the reality of diagnostic microbiology. A case study at the beginning of each chapter provides you with the opportunity to form your own questions and answers through discussion points. Hands-on procedures describe exactly what takes place in the micro lab, making content more practical and relevant. Agents of bioterrorism chapter furnishes you with the most current information about this hot topic. Issues to Consider boxes encourages you to analyze important points. Case Checks throughout each chapter tie content to case studies for improved understanding. Bolded key terms at the beginning of each chapter equip you with a list of the most important and relevant terms in each chapter. Learning objectives at the beginning of each chapter supply you with a measurable outcome to achieve by completing the material. Review questions for each learning objective help you think critically about the information in each chapter, enhancing your comprehension and retention of material. Learning assessment questions at the conclusion of each chapter allow you to evaluate how well you have mastered the material. Points to Remember sections at the end of each chapter identify key concepts in a quick-reference, bulleted format. An editable and printable lab manual provides you with additional opportunities to learn course content using real-life scenarios with questions to reinforce concepts. Glossary of key terms at the end of the book supplies you with a quick reference for looking up definitions. NEW! Content about Zika and other viruses supplies students with the latest information on prevention, treatment modalities, and CDC guidelines. NEW! Expanded Molecular Diagnostics chapter analyzes and explains new and evolving techniques. NEW! Updated photos helps familiarize you with the equipment you’ll use in the lab. NEW! Reorganized and refocused Mycology chapter helps you better understand the toxicity of fungi. NEW! Updated content throughout addresses the latest information in diagnostic microbiology.

The Complex World of Polysaccharides

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535108190
Total Pages : 652 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis The Complex World of Polysaccharides by : Desiree Nedra Karunaratne

Download or read book The Complex World of Polysaccharides written by Desiree Nedra Karunaratne and published by BoD – Books on Demand. This book was released on 2012-10-31 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex world of polysaccharides is a compilation of the characteristics of a variety of polysaccharides from plants, animals and microorganisms. The diversity of these polysaccharides arises from the structural variations and the monosaccharide content which is under genetic control. The chemical and physical properties have made them useful in many pharmaceutical, food and industrial applications. These properties of the polysaccharides determine their biological activity and their function in various applications. The role played by polysaccharides in preservation and protection of food, as carriers of nutrients and drugs, their ability to interact with molecules both for efficient delivery as well as improving textures of food colloids and their use as therapeutics are some of the functions discussed.

Oral Biofilms

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068527
Total Pages : 247 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Oral Biofilms by : S. Eick

Download or read book Oral Biofilms written by S. Eick and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-21 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.