Biodefense

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Biodefense in the Age of Synthetic Biology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309465184
Total Pages : 189 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Biodefense in the Age of Synthetic Biology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

American Biodefense

Author : Frank L. Smith III
Publisher : Cornell University Press
ISBN 13 : 0801455154
Total Pages : 205 pages
Book Rating : 4.8/5 (14 download)

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Book Synopsis American Biodefense by : Frank L. Smith III

Download or read book American Biodefense written by Frank L. Smith III and published by Cornell University Press. This book was released on 2014-09-19 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological weapons have threatened U.S. national security since at least World War II. Historically, however, the U.S. military has neglected research, development, acquisition, and doctrine for biodefense. Following September 11 and the anthrax letters of 2001, the United States started spending billions of dollars per year on medical countermeasures and biological detection systems. But most of this funding now comes from the Department of Health and Human Services rather than the Department of Defense. Why has the U.S. military neglected biodefense and allowed civilian organizations to take the lead in defending the country against biological attacks? In American Biodefense, Frank L. Smith III addresses this puzzling and largely untold story about science, technology, and national security.Smith argues that organizational frames and stereotypes have caused both military neglect and the rise of civilian biodefense. In the armed services, influential ideas about kinetic warfare have undermined defense against biological warfare. The influence of these ideas on science and technology challenges the conventional wisdom that national security policy is driven by threats or bureaucratic interests. Given the ideas at work inside the U.S. military, Smith explains how the lessons learned from biodefense can help solve other important problems that range from radiation weapons to cyber attacks.

Breeding Bio Insecurity

Author : Lynn C. Klotz
Publisher : University of Chicago Press
ISBN 13 : 0226444074
Total Pages : 269 pages
Book Rating : 4.2/5 (264 download)

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Book Synopsis Breeding Bio Insecurity by : Lynn C. Klotz

Download or read book Breeding Bio Insecurity written by Lynn C. Klotz and published by University of Chicago Press. This book was released on 2009-10-15 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the 9/11 attacks—and the subsequent lethal anthrax letters—the United States has spent billions of dollars on measures to defend the population against the threat of biological weapons. But as Lynn C. Klotz and Edward J. Sylvester argue forcefully in Breeding Bio Insecurity, all that money and effort hasn’t made us any safer—in fact, it has made us more vulnerable. Breeding Bio Insecurity reveals the mistakes made to this point and lays out the necessary steps to set us on the path toward true biosecurity. The fundamental problem with the current approach, according to the authors, is the danger caused by the sheer size and secrecy of our biodefense effort. Thousands of scientists spread throughout hundreds of locations are now working with lethal bioweapons agents—but their inability to make their work public causes suspicion among our enemies and allies alike, even as the enormous number of laboratories greatly multiplies the inherent risk of deadly accidents or theft. Meanwhile, vital public health needs go unmet because of this new biodefense focus. True biosecurity, the authors argue, will require a multipronged effort based in an understanding of the complexity of the issue, guided by scientific ethics, and watched over by a vigilant citizenry attentive to the difference between fear mongering and true analysis of risk. An impassioned warning that never loses sight of political and scientific reality, Breeding Bio Insecurity is a crucial first step toward meeting the evolving threats of the twenty-first century.

Applied Biosecurity: Global Health, Biodefense, and Developing Technologies

Author : Ryan N. Burnette
Publisher : Springer Nature
ISBN 13 : 303069464X
Total Pages : 170 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Applied Biosecurity: Global Health, Biodefense, and Developing Technologies by : Ryan N. Burnette

Download or read book Applied Biosecurity: Global Health, Biodefense, and Developing Technologies written by Ryan N. Burnette and published by Springer Nature. This book was released on 2021-05-31 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes an adaptable biothreat assessment process to complement overall biorisk management programs, incorporating threat management and the unique natures of biological assets. Further, this book examines the nexus between public health, international security, and developing technologies, building a case for augmenting biosecurity to levels beyond the laboratory constraints. With the face of biological and biomedical sciences changing, this book describes how with proper biosecurity development, these can become assets, rather than liabilities, to secure our world from natural and man-made biological disasters. The world is changing rapidly with respect to developing threats, such as terrorism, and dual-use technologies, such as synthetic biology, that are challenging how we think about biosafety and biosecurity. Further, the fields of public health and international security are colliding, as both of these share the common enemy: intentional or natural biological incidents. To date, biosecurity has been limited to laboratory-level application, and complicating efforts, and lacks credentialed biosecurity professionals skilled in both the biological sciences and threat management techniques. The result is a fragmented field of practice, with tremendous need, from the lab to the outbreak. Underpinning these principles is the SARS-CoV-2 coronavirus pandemic, providing a historic milestone to examine biosecurity through a global lens. This book describes biosecurity as a set of practices and principles to be augmented out of the constrained laboratory environment, and applied to larger efforts, such as international threat reduction and biological incident management.

Biosecurity and Bioterrorism

Author : Jeffrey Ryan
Publisher : Butterworth-Heinemann
ISBN 13 : 0128020571
Total Pages : 394 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biosecurity and Bioterrorism by : Jeffrey Ryan

Download or read book Biosecurity and Bioterrorism written by Jeffrey Ryan and published by Butterworth-Heinemann. This book was released on 2016-02-18 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosecurity and Bioterrorism, Second Edition, takes a holistic approach to biosecurity, with coverage of pathogens, prevention, and response methodology. It addresses these hazards in the context of vulnerability assessments and the planning strategies government and industry can use to prepare for and respond to such events. The book is organized into four thematic sections: Part I provides a conceptual understanding of biowarfare, bioterrorism and the laws we have to counteract this; Part II investigates known bioagents and the threat from emerging diseases; Part III focuses on agricultural terrorism and food security; and Part IV outlines international, US, and local initiatives for biodefense and biosecurity. Case studies illustrate biodefense against both intentional terrorism and natural outbreaks. - Covers emerging threats of pandemic influenza, antibiotic resistant strains of bacterial pathogens, and severe respiratory diseases caused by novel viruses - Offers increased international coverage, including initiatives to counter biological weapons and threats, and food security - Updated throughout with latest protocols for dealing with biological threats and new case studies - Includes online instructor ancillaries - PowerPoint lecture slides, test questions, and an instructor manual, for increased classroom functionality

Giving Full Measure to Countermeasures

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309166519
Total Pages : 160 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Giving Full Measure to Countermeasures by : National Research Council

Download or read book Giving Full Measure to Countermeasures written by National Research Council and published by National Academies Press. This book was released on 2004-04-06 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, substantial efforts have been initiated to develop new drugs, vaccines, and other medical interventions against biological agents that could be used in bioterrorist attacks against civilian populations. According to a new congressionally mandated report from the Institute of Medicine and National Research Council of the National Academies, to successfully develop these drugs, vaccines, and other medical interventions against biowarfare agents, Congress should authorize the creation of a new agency within the Office of the Secretary of the U.S. Department of Defense. The committee recommended that Congress should improve liability protections for those who develop and manufacture these products, to stimulate willingness to invest in new research and development for biowarfare protection. Giving Full Measure to Countermeasures also identifies other challengesâ€"such as the need for appropriate animal models and laboratories equipped with high-level biosafety protectionsâ€"that will require attention if DoD efforts to develop new medical countermeasures are to be successful.

Biosecurity in the Global Age

Author : David Fidler
Publisher : Stanford University Press
ISBN 13 : 0804750297
Total Pages : 321 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Biosecurity in the Global Age by : David Fidler

Download or read book Biosecurity in the Global Age written by David Fidler and published by Stanford University Press. This book was released on 2008 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The renewed threat of biological weapons highlights the importance of crafting policy responses informed by the rule of law. This book explores patterns in recent governance initiatives and advocates building a "global biosecurity concert" as a way to address the threats presented by biological weapons and infectious diseases in the early 21st century."--BOOK JACKET.

Nanotechnology to Aid Chemical and Biological Defense

Author : Terri A. Camesano
Publisher : Springer
ISBN 13 : 9401772185
Total Pages : 227 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Nanotechnology to Aid Chemical and Biological Defense by : Terri A. Camesano

Download or read book Nanotechnology to Aid Chemical and Biological Defense written by Terri A. Camesano and published by Springer. This book was released on 2015-10-13 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents research into chemical, biological, radiological and nuclear (CBRN) defense and environmental security, exploring practical implications of the research. Contributions from a diverse group of international civilian researchers present the latest work on nanotechnology problems in this area, looking at detection, protective technologies, decontamination and threats to environmental security due to bacteriophages and nanomaterials. Highlights include the potential of Atomic Force Microscopy (AFM) to characterize the nanoscale properties of microbial pathogens, the development of bacteriophage-based therapeutics, prophylactic and diagnostic preparations and their uses in different fields, such as medicine, veterinary, agriculture, food and water safety, amongst others. Readers may also consider an inexpensive bioassay suited for assessing chemical poisoning in the environment such as the presence of pesticides, sensors to detect ultra-trace quantities of the explosive Pentaerythritol tetranitrate (PETN) using nanotubes and electrochemical sensors to simultaneously detect and reduce the explosive trinitrotoluene (TNT) to 2,4,6-triaminotoluene (TAT) in solution. This book shows how cooperative research among NATO countries and NATO partners can make a critical contribution to meeting the opportunities and challenges of nanotechnology problems relevant to chemical and biological defense needs. The papers presented here are representative of contributions made to the Advanced Research Workshop (ARW) on September 22-26, 2014 in Antalya, Turkey, to address the NATO SPS Key Priority of Defense against CBRN Agents and Environmental Security.

Biodefense

Author : Michael S. Bronze
Publisher : Taylor & Francis
ISBN 13 : 9781904933120
Total Pages : 838 pages
Book Rating : 4.9/5 (331 download)

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Book Synopsis Biodefense by : Michael S. Bronze

Download or read book Biodefense written by Michael S. Bronze and published by Taylor & Francis. This book was released on 2005 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: The anthrax attacks by bioterrorists in the USA in October 2001 served to highlight our vulnerability to biological warfare and to act as an impetus for a massive increase in funding for biodefense research. In this timely book, top biodefense experts critically review every aspect of this complex issue. The microbiology, diagnosis, pathogenesis, epidemiology, infection control and novel therapeutics for all the key pathogens involved are comprehensively covered. Biodefense is currently focused on anthrax, smallpox, plague, tularemia, botulism and viral hemorrhagic fevers and entire chapters are devoted to each of these topics. Further chapters cover the bioterrorism threat from other diseases including brucellosis, glanders, melioidosis, psittacosis, Q fever, typhoid, gastroenteritis and cryptosporidiosis. Biological toxins derived from living organisms, such as the epsilon toxin derived from Clostridium perfringens, mycotoxins and plant-derived toxins such as ricin are also reviewed in detail. Two fascinating chapters are devoted to agroterrorism, the use of infectious agents that target animals and plants to decimate the food supply. Additional chapters cover emerging pathogens and novel bio-engineered agents that could be used in bioterrorism. The book also covers hospital preparedness, infection control, psychosocial issues, and the evolving methods for surveillance and detection in biodefence.

Biodefense Research Methodology and Animal Models, Second Edition

Author : James R. Swearengen
Publisher : CRC Press
ISBN 13 : 1439836329
Total Pages : 427 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Biodefense Research Methodology and Animal Models, Second Edition by : James R. Swearengen

Download or read book Biodefense Research Methodology and Animal Models, Second Edition written by James R. Swearengen and published by CRC Press. This book was released on 2012-02-16 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA’s Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Research Methodology and Animal Models, Second Edition spans the spectrum of coverage from basic research to advanced development of medical countermeasures. Topics discussed in this volume include: A history of biological agents as weapons, from the use of corpses to contaminate water supplies to modern day anthrax attacks Concepts and strategies involved in biowarfare and bioterrorism The development, validation, and importance of animal models in biodefense research Infectious disease aerobiology Studies involving anthrax, glanders, plague, tularemia, Q fever, alphaviruses, orthopoxviruses, and a new chapter on brucellosis Animal models for viral hemorrhagic fevers Botulinum and Ricin toxins Staphylococcal and streptococcal superantigens As the scientific community works diligently to protect the world’s population from the misuse of infectious organisms and toxins, it is imperative that researchers stay abreast of the latest techniques for biodefense research. Exploring in vivo and in vitro assays, this volume brings researchers up to date on the latest information on bacterial and viral infectious agents and biological toxins considered to pose the greatest threats to public safety. In addition, the contributors take a step toward minimizing the use of animals in further experiments by presenting documented findings that can be built upon.

Chemical-Biological Defense

Author : Albert J. Mauroni
Publisher : Bloomsbury Publishing USA
ISBN 13 : 0313069719
Total Pages : 275 pages
Book Rating : 4.3/5 (13 download)

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Book Synopsis Chemical-Biological Defense by : Albert J. Mauroni

Download or read book Chemical-Biological Defense written by Albert J. Mauroni and published by Bloomsbury Publishing USA. This book was released on 1998-06-30 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Gulf War has been the only conflict in the last half-century that featured the possible use of chemical-biological weapons against U.S. forces. Vulnerability to such an attack spurred the Department of Defense to action from the first hint of trouble in August 1990 through the end of hostilities in March 1991. Nearly disbanded in 1972, the U.S. Army Chemical Corps would be the prime force in ensuring that U.S. forces could both survive and sustain combat operations under chemical-biological warfare conditions. Focussing on the work of senior Army officials, this account assesses the degree of readiness achieved by the ground war's initiation and the lessons learned since the conflict. For an appropriately trained and equipped military force, chemical weapons pose not the danger of mass destruction but the threat of mass disruption, no more deadly than smart munitions or B-52 air strikes. This book will reveal a coordinated response to train and equip U.S. forces did take place prior to the feared Iraqi chemical and biological attacks. Undocumented in any other book, it details the plans that rushed sixty Fox reconnaissance vehicles to the Gulf, the worldwide call for protective suits and masks, and the successful placement of biological agent detectors prior to the air offensive. In addition, the work addresses what really happened at Khamisiyah. Were troops exposed to chemical weapons and what is behind the mysterious Gulf War Syndrome?

Bio-Imperialism

Author : Gwen Shuni D'Arcangelis
Publisher : Rutgers University Press
ISBN 13 : 1978815166
Total Pages : 123 pages
Book Rating : 4.9/5 (788 download)

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Book Synopsis Bio-Imperialism by : Gwen Shuni D'Arcangelis

Download or read book Bio-Imperialism written by Gwen Shuni D'Arcangelis and published by Rutgers University Press. This book was released on 2020-12-18 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bio-Imperialism focuses on an understudied dimension of the war on terror: the fight against bioterrorism. This component of the war enlisted the biosciences and public health fields to build up the U.S. biodefense industry and U.S. global disease control. The book argues that U.S. imperial ambitions drove these shifts in focus, aided by gendered and racialized discourses on terrorism, disease, and science. These narratives helped rationalize American research expansion into dangerous germs and bioweapons in the name of biodefense and bolstered the U.S. rationale for increased interference in the disease control decisions of Global South nations. Bio-Imperialism is a sobering look at how the war on terror impacted the world in ways that we are only just starting to grapple with.

Biodefense

Author : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Bioterrorism and Public Health Preparedness
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Biodefense by : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Bioterrorism and Public Health Preparedness

Download or read book Biodefense written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Bioterrorism and Public Health Preparedness and published by . This book was released on 2005 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Federal Biodefense Readiness

Author : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions
Publisher :
ISBN 13 :
Total Pages : 64 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Federal Biodefense Readiness by : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions

Download or read book Federal Biodefense Readiness written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions and published by . This book was released on 2003 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Department of Homeland Security Bioterrorism Risk Assessment

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309120284
Total Pages : 172 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Department of Homeland Security Bioterrorism Risk Assessment by : National Research Council

Download or read book Department of Homeland Security Bioterrorism Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2009-01-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mission of Department of Homeland Security Bioterrorism Risk Assessment: A Call for Change, the book published in December 2008, is to independently and scientifically review the methodology that led to the 2006 Department of Homeland Security report, Bioterrorism Risk Assessment (BTRA) and provide a foundation for future updates. This book identifies a number of fundamental concerns with the BTRA of 2006, ranging from mathematical and statistical mistakes that have corrupted results, to unnecessarily complicated probability models and models with fidelity far exceeding existing data, to more basic questions about how terrorist behavior should be modeled. Rather than merely criticizing what was done in the BTRA of 2006, this new NRC book consults outside experts and collects a number of proposed alternatives that could improve DHS's ability to assess potential terrorist behavior as a key element of risk-informed decision making, and it explains these alternatives in the specific context of the BTRA and the bioterrorism threat.

Barriers to Bioweapons

Author : Sonia Ben Ouagrham-Gormley
Publisher : Cornell University Press
ISBN 13 : 0801471923
Total Pages : 237 pages
Book Rating : 4.8/5 (14 download)

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Book Synopsis Barriers to Bioweapons by : Sonia Ben Ouagrham-Gormley

Download or read book Barriers to Bioweapons written by Sonia Ben Ouagrham-Gormley and published by Cornell University Press. This book was released on 2014-12-15 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: In both the popular imagination and among lawmakers and national security experts, there exists the belief that with sufficient motivation and material resources, states or terrorist groups can produce bioweapons easily, cheaply, and successfully. In Barriers to Bioweapons, Sonia Ben Ouagrham-Gormley challenges this perception by showing that bioweapons development is a difficult, protracted, and expensive endeavor, rarely achieving the expected results whatever the magnitude of investment. Her findings are based on extensive interviews she conducted with former U.S. and Soviet-era bioweapons scientists and on careful analysis of archival data and other historical documents related to various state and terrorist bioweapons programs.Bioweapons development relies on living organisms that are sensitive to their environment and handling conditions, and therefore behave unpredictably. These features place a greater premium on specialized knowledge. Ben Ouagrham-Gormley posits that lack of access to such intellectual capital constitutes the greatest barrier to the making of bioweapons. She integrates theories drawn from economics, the sociology of science, organization, and management with her empirical research. The resulting theoretical framework rests on the idea that the pace and success of a bioweapons development program can be measured by its ability to ensure the creation and transfer of scientific and technical knowledge. The specific organizational, managerial, social, political, and economic conditions necessary for success are difficult to achieve, particularly in covert programs where the need to prevent detection imposes managerial and organizational conditions that conflict with knowledge production.

Infectious Disease Informatics

Author : Hsinchun Chen
Publisher : Springer Science & Business Media
ISBN 13 : 1441912789
Total Pages : 217 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Infectious Disease Informatics by : Hsinchun Chen

Download or read book Infectious Disease Informatics written by Hsinchun Chen and published by Springer Science & Business Media. This book was released on 2010-03-12 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer-based infectious disease surveillance systems are capable of real-time or near real-time detection of serious illnesses and potential bioterrorism agent exposures and represent a major step forward in disease surveillance. Infectious Disease Informatics: Syndromic Surveillance for Public Health and Bio-Defense is an in-depth monograph that analyzes and evaluates the outbreak modeling and detection capabilities of existing surveillance systems under a unified framework, and presents the first book-length coverage of the subject from an informatics-driven perspective. Individual chapters consider the state of the art, including the facilitation of data collection, sharing and transmission; a focus on various outbreak detection methods; data visualization and information dissemination issues; and system assessment and other policy issues. Eight chapters then report on several real-world case studies, summarizing and comparing eight syndromic surveillance systems, including those that have been adopted by many public health agencies (e.g., RODS and BioSense). The book concludes with a discussion of critical issues and challenges, with a look to future directions. This book is an excellent source of current information for researchers in public health and IT. Government public health officials and private-sector practitioners in both public health and IT will find the most up-to-date information available, and students from a variety of disciplines, including public health, biostatistics, information systems, computer science, and public administration and policy will get a comprehensive look at the concepts, techniques, and practices of syndromic surveillance.