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Biochemistry Of Diabetes And Atherosclerosis
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Book Synopsis Biochemistry of Diabetes and Atherosclerosis by : James S.C. Gilchrist
Download or read book Biochemistry of Diabetes and Atherosclerosis written by James S.C. Gilchrist and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is an autoimmune, inflammatory disease affecting many different organ systems and exhibiting both primary and secondary defects. Because diabetes affects a wide range of cellular systems, a multidisciplinary effort has been mounted over the past several decades using a wide range of investigative techniques and methodologies in order to identify molecular mechanisms responsible for cellular dysfunction. Because primary defects at various levels of sub-cellular signaling, intracellular calcium handling, protein expression and energy regulation are often a primary consequence of diabetes. This volume is a compilation of new multidisciplinary research that will broaden our current understanding of diabetes and cardiovascular disease as well as provide the basis for the development of novel therapeutic interventions.
Book Synopsis Diabetic Cardiomyopathy by : Belma Turan
Download or read book Diabetic Cardiomyopathy written by Belma Turan and published by Springer Science & Business Media. This book was released on 2014-01-08 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double within the next 20 years. Among the 3.8 million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy. Twenty five articles in this book are organized in three sections. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural alterations in heart. In the second section, several cellular and molecular mechanisms are discussed indicating that diabetic cardiomyopathy is a multifactorial and complex problem. The third section discusses the prevention and treatment of diabetes using appropriate diet, proper supplements including antioxidants, angiotensin inhibitors and some other drugs. All in all, this book discusses the diverse mechanisms of diabetic cardiomyopathy with some information on new therapeutic approaches for finding solutions to prevent or reverse the development of cardiac dysfunction.
Book Synopsis Lipoproteins in Diabetes Mellitus by : Alicia J. Jenkins
Download or read book Lipoproteins in Diabetes Mellitus written by Alicia J. Jenkins and published by Springer Science & Business Media. This book was released on 2014-01-08 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.
Book Synopsis Biochemistry of Atherosclerosis by : Sukhinder C. Kaur
Download or read book Biochemistry of Atherosclerosis written by Sukhinder C. Kaur and published by Springer Science & Business Media. This book was released on 2006-08-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. It includes all aspects of the regulation of cholesterol homeostasis and the importance of each pathway. Also explored are the roles of nuclear hormone receptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis. The book further discusses how genetic studies can help understand the complexities that mediate these aspects of atherogenesis.
Download or read book Diabetes written by J. Vallance-Owen and published by Springer. This book was released on 1975-11-30 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dyslipoproteinaemias and Diabetes by : European Atherosclerosis Group. Meeting
Download or read book Dyslipoproteinaemias and Diabetes written by European Atherosclerosis Group. Meeting and published by S. Karger AG (Switzerland). This book was released on 1985 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book features clinical and experimental data covering four major topics. General treatment of hyperlipidaemias is reviewed including the efficacy of different drugs. Benefits of treatment by the Lipid Research Clinics Coronary Primary Prevention Trial are shown. The second topic comprises the epidemiological aspects of diabetes. Diabetes and lipoprotein metabolism is the subject of the third are considered. VLDL metabolism and apoprotein metabolism are reviewed and complimented by a general consideration of protein glycosylation and the possible pathophysiological consequences of the glycosylation of LDL and HDL. The final topic reflects the growing interest in the molecural biology of hyperlipidaemias. The genetic determinants of hyperlipidaemias are reviewed as well as links between genetic disorders, diabetes and hyperlipidaemias. [Editeur]
Book Synopsis Carbohydrate Metabolism by : F. Dickens
Download or read book Carbohydrate Metabolism written by F. Dickens and published by Elsevier. This book was released on 2014-05-12 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Metabolism and its Disorders focuses on the processes and methodologies involved in carbohydrate metabolism, including detection of diabetes, hypoglycemic syndromes, cardiovascular diseases, and atherosclerosis. The selection first takes a look at the detection of diabetes in man, hormonal disturbances in diabetes, and hypoglycemia. Topics include indications for testing for diabetes, reasons for early detection, testing for diabetes with tolbutamide, glucagon, corticosteroids, and hypoglycemic syndromes. The book also ponders on the physiological aspects of carbohydrate metabolism in the fetus and newborn and glycogen-storage diseases. The publication examines dietary intake of carbohydrate in relation to diabetes and atherosclerosis and glucose tolerance in ischemic cardiovascular disease. Discussions focus on epidemiological studies of diabetes and atherosclerosis, overt diabetes mellitus, and effects of selection, age, obesity, and other factors. The book also identifies disturbances of the digestion and absorption of carbohydrates; insulin antagonists and disturbances in carbohydrate metabolism; and glycosaminoglycans in joint disorders. The selection is a valuable reference for readers interested in carbohydrate metabolism.
Author :Daniel Rajdl a kol. Publisher :Charles University in Prague, Karolinum Press ISBN 13 :8024631644 Total Pages :883 pages Book Rating :4.0/5 (246 download)
Book Synopsis Clinical Biochemistry by : Daniel Rajdl a kol.
Download or read book Clinical Biochemistry written by Daniel Rajdl a kol. and published by Charles University in Prague, Karolinum Press. This book was released on 2016-08-01 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: The textbook is essential for medical students and can serve as a reference for young doctors in postgraduate training. It covers all major topics of clinical biochemistry: from preanalytical issues, acid-base balance and ion dysbalances, via special topics (diabetes mellitus, gastrointestinal tract or laboratory investigation of important organs - liver, kidney, heart) to therapeutic drugs monitoring and trends in laboratory medicine. Authors are leading experts in clinical biochemistry. The topics are presented in readable and comprehensive form and are suplemented by intractive e-learning course with control quizzes.
Book Synopsis Cardiovascular and Metabolic Disease by : Philip Peplow
Download or read book Cardiovascular and Metabolic Disease written by Philip Peplow and published by Royal Society of Chemistry. This book was released on 2015-05-22 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular and metabolic diseases remain the number one cause of death in developed countries and their prevalence is increasing rapidly in developing nations. This book brings together the recent information on these disorders and the links that exist between them in order to provide a complete picture of drug discovery for these conditions. The main three sections comprehensively discuss obesity, hypertension and cardiovascular disease, and diabetes in turn, following an introduction to the molecular links between them. The final chapter provides perspectives on future directions of the field. Chapters are contributed by leaders in the field from academia and industry and cover biomarkers, risk factors, gene-environment interactions, therapies and the various types of animal models that have been used to study each disease. Case studies describing the implementation of animal models in drug development further enhance the book’s usefulness as a comprehensive guide to this important therapeutic area. Providing a full picture of the various types of animal models that have been used to study obesity, hypertension, and insulin resistance with recent case studies, this book provides a valuable resource for medicinal chemists and clinicians working in these disease areas.
Book Synopsis The Glycation Hypothesis of Atherosclerosis by : Camilo A. L. S. Colaco
Download or read book The Glycation Hypothesis of Atherosclerosis written by Camilo A. L. S. Colaco and published by . This book was released on 1997 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Glycation Hypothesis of Atherosclerosis by : Camilo A. L. S. Colaco
Download or read book The Glycation Hypothesis of Atherosclerosis written by Camilo A. L. S. Colaco and published by . This book was released on 1997-01-01 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: As cardiovascular disease is a major cause of death in the western world, it is essential that we understand the pathogenesis of atherosclerosis. Although cholesterol has caught the public's attention, oxidized LDL is, scientifically, the major risk factor. The book explains what glycation is and how it could lead to the oxidation of LDL. It also summarizes the data on dietary sugars as risk factors and on diabetics as, in effect, an experimental model for atherosclerosis.
Book Synopsis Atlas of Atherosclerosis and Metabolic Syndrome by : Scott M. Grundy
Download or read book Atlas of Atherosclerosis and Metabolic Syndrome written by Scott M. Grundy and published by Springer Science & Business Media. This book was released on 2011-03-14 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is an integral source of information on Atherosclerosis. It covers topics such as newer coronary risk factors, high-density lipoprotein metabolism, lipid-lowering drugs, endothelium and thrombosis in atherogenesis, and contributing risk factors. With over 500 exceptional photographs, diagrams, and charts, each chapter illustrates an important facet of diagnosing and treating this common and often fatal disease.
Book Synopsis Phytotherapy in the Management of Diabetes and Hypertension by : Mohamed Eddouks
Download or read book Phytotherapy in the Management of Diabetes and Hypertension written by Mohamed Eddouks and published by Bentham Science Publishers. This book was released on 2012-11-20 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytotherapy in the Management of Diabetes and Hypertension is a good addition to existing volumes detailing knowledge of hyperglycemia therapy. This e-book emphasizes the basic biochemistry behind diabetes mellitus and hypertension, along with the control or remediation of these conditions through a cost effective, safe, easy-going, easy-adaptable method validated by scientific research. This e-book contains 7 chapters dealing with various aspects of these diseases and their Phytotherapy treatment and life style management. Phytotherapy can give patients long term benefits with less or no side effects. Hence, this e-book is an authentic alternative or complementary therapeutic compendium to physicians and patients. This book will also be useful to students, teachers, researchers, clinicians and general readers interested in learning about applied phytotherapy.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Book Synopsis Diabetes Complications, Comorbidities and Related Disorders by : Enzo Bonora
Download or read book Diabetes Complications, Comorbidities and Related Disorders written by Enzo Bonora and published by Springer. This book was released on 2020-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with comprehensive information on the interactions between diabetes and a wide range of comorbid conditions and on disease management in such patients. It has the aim of empowering health care providers in their daily battle against the disease and its consequences. Diabetes has been identified by WHO and the United Nations as a medical emergency because of the increase in its global prevalence, which may reach one billion in three to four decades if the trend remains unchanged. Despite improved care that is helping to prolong life, diabetes impacts substantially on the quality of life of those affected and kills or disables several million people each year. The disease is systemic because all organs, tissues, and cells suffer in the presence of hyperglycemia and are damaged by the diabetic milieu. Unfortunately, most patients with diabetes will consequently experience chronic diabetic complications. This book will be of value for all physicians and nurses who care for patients with diabetes and face the challenge of treating hyperglycemia and related acute and chronic complications.
Book Synopsis Progression of Subclinical Atherosclerosis in Type 2 Diabetes by : Ling Zheng
Download or read book Progression of Subclinical Atherosclerosis in Type 2 Diabetes written by Ling Zheng and published by . This book was released on 2005 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Diabetes Textbook by : Joel Rodriguez-Saldana
Download or read book The Diabetes Textbook written by Joel Rodriguez-Saldana and published by Springer. This book was released on 2019-06-27 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sources: the surge of scientific advances contrast with an unprecedented amount of human suffering. Thus, a patient centered and an evidence based approach with the capacity to produce measurable clinical and economic outcomes is required. The purpose of this textbook is multiple: to offer a comprehensive resource covering all aspects of outpatient management; to address diabetes as a health problem from an epidemiological, economic and clinical perspective; to discuss the role of social determinants of health on the worldwide increase in diabetes; to highlight the challenges and obstacles in providing adequate care; and to outline a multidisciplinary approach to management in which medical visits retain their importance as part of a team comprising the patient, his or her family and a multidisciplinary group of health professionals who are able to move beyond the traditional approach of diabetes as a disease and greatly improve outcomes.
