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Author : Robert Filler
Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biochemistry Involving Carbon-fluorine Bonds written by Robert Filler and published by . This book was released on 1976 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shinji Murai
Publisher : Springer
ISBN 13 : 3540685251
Total Pages : 275 pages
Book Rating : 4.5/5 (46 download)
Download or read book Activation of Unreactive Bonds and Organic Synthesis written by Shinji Murai and published by Springer. This book was released on 2003-07-01 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few years a large repetoire of methods for the activation of unreactive organic functionalities and for their use in organic synthesis has been developed. In this volume, areas ranging from the activation of C-H bonds to the chemical transformation of dinitrogen are authoritatively discussed by leading experts in the field. To activate means to be able to cleave otherwise inert chemical bonds. The cleavage and formation of chemical bonds is fundamental to organic synthesis; these new activation methodologies make hitherto infeasible reactions extremely easy and create new opportunities for innovative organic transformations, for both industry and academia. This is the first book that provides a thorough and timely coverage of both inorganic and organic synthetic aspects of bond activation, thus giving a broad overview of the field and allowing both inorganic and organic chemists ready access to the methodologies involved.
Author : Kenneth L. Kirk
Publisher : Springer Science & Business Media
ISBN 13 : 1468458175
Total Pages : 305 pages
Book Rating : 4.4/5 (684 download)
Download or read book Biochemistry of the Elemental Halogens and Inorganic Halides written by Kenneth L. Kirk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The elements in group 17 (VIlA) of the periodic table of elements-fluorine (F), chlorine (CI), bromine (Br), and iodine (I)-were designated by Berzelius as "halogens" (Greek hals, sea salt; gennao, I beget) because of their propensity to form salts. In this first of the two volumes of Bio chemistry of the Halogens, the biochemistry of the elemental halogens and inorganic halides is reviewed. Discovery, properties, and biochemistry of the elemental halogens are reviewed first (Chapter 1). This is followed by a review of the developments in the various areas of inorganic halide biochemistry (Chapters 2 through 5). The biochemistry of thyroid hor mones is considered in Chapter 6, while biohalogenation, an important link between inorganic and organic halogen biochemistry, is reviewed in Chapter 7. Chapter 8 covers the biochemistry of products produced by human-inspired halogenation, in particular, poly halogenated compounds that present environmental problems. In Chapter 9, the process is reversed and biodehalogenation is reviewed. In each subject, the attempt has been made to find an appropriate balance between depth and breadth of treatment, since a thorough, in depth review of this field would not be possible in a single volume. To provide readers not familiar with subjects with the necessary background to place subsequent discussions in perspective, brief historical develop ments of many of the topics are given.
Author : Kenneth L. Kirk
Publisher : Springer Science & Business Media
ISBN 13 : 1475746059
Total Pages : 374 pages
Book Rating : 4.4/5 (757 download)
Download or read book Biochemistry of Halogenated Organic Compounds written by Kenneth L. Kirk and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Halogenated Organic Compounds has been written as a general reference source for researchers in several related areas, including organic chemists, medicinal chemists, pharmacologists, toxicologists, and medical researchers. The development of halogenated compounds as medicinal agents and pharmacological tools and the fascinating biochemi cal processes that have been discovered and studied using these analogues have generated extremely active areas of research and an enormous volume of literature. Thus, halogenated organic compounds pervade every aspect of biochemistry, a fact made apparent by the numerous reviews and monographs available on individual topics-halogenated nucleosides, halogenated carbohydrates, and so forth. Given the quantity of material already written on these topics, some of which material is quite current, it might be asked whether a one-volume review of these subjects is useful, or possible. Having now completed this work, I feel the answer to both questions is an emphatic yes. There are fascinating stories to be related in each area, and, where appropriate, I have attempted to develop these topics . from a historical perspective. For example, the discovery of the anticancer activity of fluorouracil, the unraveling of the several mechanisms of its action, and the development of a host of later generations of anticancer and antiviral agents based on the parent fluoro-, iodo-, bromo-, and trifluoromethylpyrimidines were, and are, contributions of major magnitude to medical science.
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1568 pages
Book Rating : 4.3/5 (91 download)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1568 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Author : Richard D. Chambers
Publisher : CRC Press
ISBN 13 : 9780849317903
Total Pages : 426 pages
Book Rating : 4.3/5 (179 download)
Download or read book Fluorine in Organic Chemistry written by Richard D. Chambers and published by CRC Press. This book was released on 2004 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of carbon-fluorine bonds into organic compounds can profoundly influence their chemical and physical properties when compared to their non-fluorine-containing analogues, leading to a range of man-made materials with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, from pharmaceuticals, through fine and specialty chemicals to polymers. From Prozac to Teflon, many of the most important products of the chemical and life-science industries rely on organic fluorine chemistry for their useful properties. This book covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems.
Author : Joanna S. Fowler
Publisher : National Academies
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.0/5 (937 download)
Download or read book The Synthesis of Carbon-11, Fluorine-18, and Nitrogen-13 Labeled Radiotracers for Biomedical Applications written by Joanna S. Fowler and published by National Academies. This book was released on 1982 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : iSmithers Rapra Publishing
ISBN 13 : 9781859570333
Total Pages : 224 pages
Book Rating : 4.5/5 (73 download)
Download or read book Fluorine in Agriculture written by and published by iSmithers Rapra Publishing. This book was released on 1995 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David E. Metzler
Publisher : Elsevier
ISBN 13 : 0080924735
Total Pages : 1059 pages
Book Rating : 4.0/5 (89 download)
Download or read book Biochemistry (2 volume set) written by David E. Metzler and published by Elsevier. This book was released on 2003-06-04 with total page 1059 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Author : Xue Duan
Publisher : Springer
ISBN 13 : 9783540104940
Total Pages : 204 pages
Book Rating : 4.1/5 (49 download)
Download or read book Metal Complexes written by Xue Duan and published by Springer. This book was released on 1981-03-01 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David E. Metzler
Publisher : Elsevier
ISBN 13 : 0080924719
Total Pages : 1063 pages
Book Rating : 4.0/5 (89 download)
Download or read book Biochemistry written by David E. Metzler and published by Elsevier. This book was released on 2003-05-04 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic chemistry and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background* Contains twice the number of chapters of the first edition* Each chapter contains boxes of information on topics of general interest
Author : Alain Tressaud
Publisher : Elsevier
ISBN 13 : 0080558119
Total Pages : 821 pages
Book Rating : 4.0/5 (85 download)
Download or read book Fluorine and Health written by Alain Tressaud and published by Elsevier. This book was released on 2008-06-06 with total page 821 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics
Author : Paul F. Cook
Publisher : CRC Press
ISBN 13 : 9780849353123
Total Pages : 656 pages
Book Rating : 4.3/5 (531 download)
Download or read book Enzyme Mechanism from Isotope Effects written by Paul F. Cook and published by CRC Press. This book was released on 1991-09-20 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.
Author : Erling Johansen
Publisher : CRC Press
ISBN 13 : 0429727348
Total Pages : 259 pages
Book Rating : 4.4/5 (297 download)
Download or read book Continuing Evaluation Of The Use Of Fluorides written by Erling Johansen and published by CRC Press. This book was released on 2019-03-04 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work addresses a variety of topics that are of interest in their own right and because they bear on the evaluation of the safety of fluoridation. The latter is important because the demonstration of "no effect" from the use of fluorides is very difficult and the available data need to be periodically reexamined to reduce the theoretical amount
Author : Earl Frieden
Publisher : Springer Science & Business Media
ISBN 13 : 1468447750
Total Pages : 433 pages
Book Rating : 4.4/5 (684 download)
Download or read book Biochemistry of the Essential Ultratrace Elements written by Earl Frieden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: The remarkable development of molecular biology has had its counterpart in an impressive growth of a segment of biology that might be described as atomic biology. The past several decades have witnessed an explosive growth in our knowledge of the many elements that are essential for life and maintenance of plants and animals. These essential elements include the bulk elements (hydro gen, carbon, nitrogen, oxygen, and sulfur), the macrominerals (sodium, potas sium, calcium, magnesium, chloride, and phosphorus), and the trace elements. This last group includes the ultra trace elements and iron, zinc, and copper. Only the ultratrace elements are featured in this book. Iron has attracted so much research that two volumes are devoted to this metal-The Biochemistry of Non-Heme Iron by A. Bezkoravainy, Plenum Press, 1980, and The Biochemistry of Heme Iron (in preparation). Copper and zinc are also represented by a separate volume in this series. The present volume begins with a discussion of essentiality as applied to the elements and a survey of the entire spectrum of possible required elements.
Author : Christopher Bryson
Publisher : Seven Stories Press
ISBN 13 : 1609800087
Total Pages : 401 pages
Book Rating : 4.6/5 (98 download)
Download or read book The Fluoride Deception written by Christopher Bryson and published by Seven Stories Press. This book was released on 2011-01-04 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the narrative punch of Jonathan Harr’s A Civil Action and the commitment to environmental truth-telling of Erin Brockovich, The Fluoride Deception documents a powerful connection between big corporations, the U.S. military, and the historic reassurances of fluoride safety provided by the nation’s public health establishment. The Fluoride Deception reads like a thriller, but one supported by two hundred pages of source notes, years of investigative reporting, scores of scientist interviews, and archival research in places such as the newly opened files of the Manhattan Project and the Atomic Energy Commission. The book is nothing less than an exhumation of one of the great secret narratives of the industrial era: how a grim workplace poison and the most damaging environmental pollutant of the cold war was added to our drinking water and toothpaste.
Author : David E. Metzler
Publisher : Academic Press
ISBN 13 : 012492543X
Total Pages : 1059 pages
Book Rating : 4.1/5 (249 download)
Download or read book Biochemistry (2 Volume Set) written by David E. Metzler and published by Academic Press. This book was released on 2003-04-04 with total page 1059 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
