Biochemical Lesions And Lethal Synthesis

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Biochemical Lesions and Lethal Synthesis

Author : Rudolph A. Peters
Publisher : Elsevier
ISBN 13 : 1483140407
Total Pages : 334 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Biochemical Lesions and Lethal Synthesis by : Rudolph A. Peters

Download or read book Biochemical Lesions and Lethal Synthesis written by Rudolph A. Peters and published by Elsevier. This book was released on 2013-10-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Series of Monographs on Pure and Applied Biology, Volume 18: Biochemical Lesions and Lethal Synthesis focuses on biochemical lesions. The book first discusses biochemical lesions in thiamine deficiency and arsenical substances and biochemical lesions. The text also examines biochemical lesions in mustard gas poisoning. Concerns include sulfone, sulfoxide, vesication, and cross-linking. The book also describes inhibitors of enzymes containing thiol groups and toxicity. Cell division, thiol agents, epidemic dropsy, and sanguinarine are highlighted. The text further focuses on lethal synthesis and carbon-flourine compounds. The synthesis of fluorocitric acid, effects of fluorocitrate, carbon-fluorine compounds, and biochemical lesions induced by fluorocitrate are discussed. The text further describes biochemical lesions in burns and historical points and other biochemical lesions. Muscular contraction, antimetabolites, inborn errors, and study of the biochemistry of burn sites are explained. The text is highly recommended for readers wanting to study biochemical lesions.

Nutritional Biochemistry of the Vitamins

Author : David A. Bender
Publisher : Cambridge University Press
ISBN 13 : 1139437739
Total Pages : 514 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Nutritional Biochemistry of the Vitamins by : David A. Bender

Download or read book Nutritional Biochemistry of the Vitamins written by David A. Bender and published by Cambridge University Press. This book was released on 2003-09-18 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative and comprehensive review of our current knowledge of the vitamins, their metabolic functions and the scientific basis for setting recommended intakes for the prevention of deficiency and promotion of optimum health. This publication will be a valuable reference for students and specialists alike in the field of nutritional biochemistry.

Mechanisms and Concepts in Toxicology

Author : W. Norman Aldridge
Publisher : CRC Press
ISBN 13 : 113574467X
Total Pages : 270 pages
Book Rating : 4.1/5 (357 download)

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Book Synopsis Mechanisms and Concepts in Toxicology by : W. Norman Aldridge

Download or read book Mechanisms and Concepts in Toxicology written by W. Norman Aldridge and published by CRC Press. This book was released on 1996-02-15 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrating concepts and types of toxicity from a mechanistic point of view, this book focuses on research procedures in toxicology. The book uses examples of chemical intoxicants to illustrate mechanisms in each stage of toxicity.

Chemical & Biological Aspects of Drug Dependence

Author : S. J. Mulé
Publisher : CRC Press
ISBN 13 : 0429536224
Total Pages : 884 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Chemical & Biological Aspects of Drug Dependence by : S. J. Mulé

Download or read book Chemical & Biological Aspects of Drug Dependence written by S. J. Mulé and published by CRC Press. This book was released on 2019-06-04 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1972 this book guides the reader through the various elements behind drug dependency and addiction. Taking an objective view at the characteristics both chemical and biological, the criteria for evaluating dependency as well as the physiological effects drug dependency can have on the human body. Biological and Chemical Aspects of Drug Dependency is a useful reference for students of both medicine and psychology alike as well as for professionals in their respective fields.

Frontiers of Bioorganic Chemistry and Molecular Biology

Author : S. N. Ananchenko
Publisher : Elsevier
ISBN 13 : 1483278832
Total Pages : 485 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Frontiers of Bioorganic Chemistry and Molecular Biology by : S. N. Ananchenko

Download or read book Frontiers of Bioorganic Chemistry and Molecular Biology written by S. N. Ananchenko and published by Elsevier. This book was released on 2017-05-04 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers of Bioorganic Chemistry and Molecular Biology covers the proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, held in Moscow and Tashkent, USSR on September 25-October 2, 1978. This symposium is devoted to a discussion of the physico-chemical basis of life processes. This book contains 56 chapters, and reflects the results in the study of peptides and proteins, nucleic acids, polysaccharides, and other biopolymers. Other chapters deal with the study of low molecular regulators, including steroids, alkaloids, and antibiotics. This book also includes discussion of the achievements in the study of genetic structures and of cellular protein synthesizing systems of the molecular basis of enzymic catalysis and of bioenergetic processes. This book will be of value to biochemists and molecular biologists.

Beriberi, White Rice, and Vitamin B

Author : Kenneth J. Carpenter
Publisher : Univ of California Press
ISBN 13 : 0520923642
Total Pages : 286 pages
Book Rating : 4.5/5 (29 download)

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Book Synopsis Beriberi, White Rice, and Vitamin B by : Kenneth J. Carpenter

Download or read book Beriberi, White Rice, and Vitamin B written by Kenneth J. Carpenter and published by Univ of California Press. This book was released on 2023-12-22 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive account of the history and treatment of beriberi, Kenneth Carpenter traces the decades of medical and chemical research that solved the puzzle posed by this mysterious disease. Caused by the lack of a minute quantity of the chemical thiamin, or vitamin B1 in the diet, beriberi is characterized by weakness and loss of feeling in the feet and legs, then swelling from fluid retention, and finally heart failure. Western doctors working in Asia after 1870 saw it as the major disease in native armed forces and prisons. It was at first attributed to miasms (poisonous vapors from damp soil) or to bacterial infections. In Java, chickens fed by chance on white rice lost the use of their legs. On brown rice, where the grain still contained its bran and germ, they remained healthy. Studies in Javanese prisons then showed beriberi also occurring where white (rather than brown) rice was the staple food. Birds were used to assay the potency of fractions extracted from rice bran and, after 20 years, highly active crystals were obtained. In another 10 years their structure was determined and "thiamin" was synthesized. Beriberi is a story of contested knowledge and erratic scientific pathways. It offers a fascinating chronicle of the development of scientific thought, a history that encompasses public health, science, diet, trade, expanding empires, war, and technology. From the preface: This is a medical detective story: beginning with the investigation of a disease that has killed or crippled at least a million people, and then following up clues that ranged much wider. One outcome was the production of a synthetic chemical that we now, nearly all of us, consume in small quantities each day in our food. The detectives had a variety of professions and spoke different languages. Their work ranged from studying the health of laborers in a primitive jungle to the painstaking dissection of individual grains of rice under a microscope. The integrated story of their struggles and successes, culled from old volumes in scattered libraries, forms the subject of this book.

Neurotoxicity of Pesticides

Author :
Publisher : Academic Press
ISBN 13 : 0128205156
Total Pages : 288 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Neurotoxicity of Pesticides by :

Download or read book Neurotoxicity of Pesticides written by and published by Academic Press. This book was released on 2020-03-21 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicity of Pesticides, Volume Four, in this comprehensive serial addresses contemporary advances in neurotoxicology of pesticides by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Organophosphates, OPs, Nerve agents, Pyrethroids, Neonicotinoids and Formamidines, among others.

The Practice of Medicinal Chemistry

Author : Camille Georges Wermuth
Publisher : Elsevier
ISBN 13 : 012417213X
Total Pages : 903 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis The Practice of Medicinal Chemistry by : Camille Georges Wermuth

Download or read book The Practice of Medicinal Chemistry written by Camille Georges Wermuth and published by Elsevier. This book was released on 2015-07-01 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. - Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field - Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts - Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research - An image bank is available for instructors at www.textbooks.elsevier.com

Foreign Compound Metabolism in Mammals

Author : D E Hathway
Publisher : Royal Society of Chemistry
ISBN 13 : 184755606X
Total Pages : 748 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Foreign Compound Metabolism in Mammals by : D E Hathway

Download or read book Foreign Compound Metabolism in Mammals written by D E Hathway and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Medical Defense Against Mustard Gas

Author : Alan J. Feister
Publisher : CRC Press
ISBN 13 : 9780849342578
Total Pages : 390 pages
Book Rating : 4.3/5 (425 download)

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Book Synopsis Medical Defense Against Mustard Gas by : Alan J. Feister

Download or read book Medical Defense Against Mustard Gas written by Alan J. Feister and published by CRC Press. This book was released on 1991-04-03 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review and analysis of the acute toxic effects of sulfur mustard (mustard gas); the injuries that this compound produces in skin, eye, airway, and other tissues; and possibilities for the prevention of these injuries through pharmacological intervention. The book takes a multidisciplinary approach and is intended for all biomedical researchers interested in combatting the effects of chemical weapons, as well as those who have a general interest in the basic processes underlying cell death and tissue injury. Drawing on an extensive base of scientific literature, including many government research reports that are difficult or impossible for most researchers to obtain, the book covers the pathological features of acute mustard injury, sulfur mustard's toxicodynamics, its chemistry, its molecular and cellular mechanisms of injury, the inflammatory mechanisms involved in injury, prophylactic and therapeutic approaches to prevention of injury, and experimental models of mustard injury.

Chemical Mediators of the Acute Inflammatory Reaction

Author : M. Rocha E Silva
Publisher : Elsevier
ISBN 13 : 1483150518
Total Pages : 276 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Chemical Mediators of the Acute Inflammatory Reaction by : M. Rocha E Silva

Download or read book Chemical Mediators of the Acute Inflammatory Reaction written by M. Rocha E Silva and published by Elsevier. This book was released on 2013-10-22 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Series of Monographs in Pure and Applied Biology, Modern Trends in Physiological Sciences, Volume 37: Chemical Mediators of the Acute Inflammatory Reaction traces the history of investigation into the acute inflammatory reaction from the early observations in invertebrates to the experiments of therapeutic significance for humans. This book focuses on mediators that are accepted as being commonly involved in the inflammatory reaction, such as histamine, kinins, serotonin, prostaglandins, and permeability factors. The topics discussed include the phagocytic system and antibody production; factors which influence phagocytosis; measurement of the acute inflammatory reaction; and combined actions of mediators. The reaction to injury and manifestation of inflammation and biochemical aspects of anti-inflammatory drug reaction are also covered. This volume is beneficial to anatomists, biochemists, physiologists, immunologists, pathologists, pharmacologists, and clinicians interested in acute inflammatory reaction.

Hayes' Handbook of Pesticide Toxicology

Author :
Publisher : Academic Press
ISBN 13 : 0080922015
Total Pages : 2407 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Hayes' Handbook of Pesticide Toxicology by :

Download or read book Hayes' Handbook of Pesticide Toxicology written by and published by Academic Press. This book was released on 2010-02-15 with total page 2407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book's tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. - Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. - Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions - All major classes of pesticide considered - Different routes of exposure critically evaluated

Photochemistry of Proteins and Nucleic Acids

Author : A. D. McLaren
Publisher : Elsevier
ISBN 13 : 1483136035
Total Pages : 470 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Photochemistry of Proteins and Nucleic Acids by : A. D. McLaren

Download or read book Photochemistry of Proteins and Nucleic Acids written by A. D. McLaren and published by Elsevier. This book was released on 2016-06-06 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photochemistry of Proteins and Nucleic Acids focuses on the effects of ultraviolet and visible radiations on proteins and nucleic acids. The book first discusses some principles of photochemistry, including the laws of photochemistry and factors influencing photochemical reactions in solutions. The text describes absorption and luminescence spectra of nucleoproteins and their components, including principal absorbing groups in proteins, nucleic acids, and nucleoproteins. The selection also highlights the action of ultraviolet light on proteins; photochemical and photosensitized inactivation of enzymes; and the photochemistry of purine and pyrimidine derivatives. The text also discusses nucleic acids and oligo- and polynucleotides. Topics include photochemical degradation of nucleic acid; kinetics of biological inactivation of nucleic acids; nucleoproteins; and reversibility of nucleic acid photolysis. The book also encompasses the inactivation of viruses, including inactivation studies with a plant virus, bacteriophages, and photochemically produced vaccines. The text also presents some problems in photobiology and some techniques in photochemistry. The text is a good source of information for readers interested in the study of proteins and nucleic acids.Based on the standards and codes from Fo

Bulletin of the Johns Hopkins Hospital

Author : Johns Hopkins Hospital
Publisher :
ISBN 13 :
Total Pages : 466 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Bulletin of the Johns Hopkins Hospital by : Johns Hopkins Hospital

Download or read book Bulletin of the Johns Hopkins Hospital written by Johns Hopkins Hospital and published by . This book was released on 1955 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bound with v. 52-55, 1933-34, is the hospital's supplement: Bulletin of the Institute of the History of Medicine, Johns Hopkins University, v. 1-2.

Human Tumours Secreting Catecholamines

Author : Henri Hermann
Publisher : Elsevier
ISBN 13 : 1483282619
Total Pages : 249 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Human Tumours Secreting Catecholamines by : Henri Hermann

Download or read book Human Tumours Secreting Catecholamines written by Henri Hermann and published by Elsevier. This book was released on 2017-01-31 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Tumors Secreting Catecholamines: Clinical and Physiopathological Study of the Pheochromocytomas focuses on the characteristics, manifestations, diagnosis, and treatment of pheochromocytomas. The manuscript first offers information on cardiovascular manifestations, metabolic and endocrine manifestations, and unusual clinical manifestations and complications. Discussions focus on permanent arterial hypertension, disturbances of glycoregulation, cardiovascular complications, and major circulatory accidents. The book then examines anatomical forms, including intrathoracic, para-aortic, urinary bladder, multiple, and malignant pheochromocytomas. The publication ponders on inherited forms and pheochromocytomas in children and pregnant women and the diagnosis and treatment of pheochromocytoma. The text also takes a look at pathological anatomy, biological investigations, and physiopathology. Topics include cardiovascular symptoms, dynamics of tumor secretion, histochemical problems, and hormone content of tumors. The manuscript is a dependable reference for readers interested in the study of pheochromocytomas.

Histophysiology of Synapses and Neurosecretion

Author : Eduardo D.P. De Robertis
Publisher : Elsevier
ISBN 13 : 148318059X
Total Pages : 260 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Histophysiology of Synapses and Neurosecretion by : Eduardo D.P. De Robertis

Download or read book Histophysiology of Synapses and Neurosecretion written by Eduardo D.P. De Robertis and published by Elsevier. This book was released on 2013-10-22 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histopbysiology of Synapses and Neurosecretion discusses the relationship between subcellular structure and function in synapses. The title discusses how neurosecretion phenomenon takes place in the important areas of central and peripheral nervous system. The first part of text deals with the synapse. Topics such as the concept of synaptic transmission, morphology of synaptic region, and ultrastructure of synaptic region are covered in the first part. Part I also discusses the MORPHO-physiological correlations in certain synapses; and neurochemical studies in isolated nerve endings and synaptic vesicles of the CNS. The second part of the selection covers neorosecretion. Part II tackles the neurohumoral mechanisms and secretion in the hypothalamicneurohypophysial system; secretory processes; and secretion in adrenergic nerves and endings. The book will be of great use to student, researchers, and practitioners of neurology.

Assay of Protein and Polypeptide Hormones

Author : H. Van Cauwenberge
Publisher : Elsevier
ISBN 13 : 1483145964
Total Pages : 255 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Assay of Protein and Polypeptide Hormones by : H. Van Cauwenberge

Download or read book Assay of Protein and Polypeptide Hormones written by H. Van Cauwenberge and published by Elsevier. This book was released on 2014-05-17 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Series of Monographs in Pure and Applied Biology, Modern Trends in Physiological Sciences, Volume 33: Assay of Protein and Polypeptide Hormones focuses on the assays of protein and polypeptide hormones. The selection first discusses the general principles of protein and polypeptide hormone assays, including conditions and basic factors for bioassays and status of biological assays. The book looks at the assays of hypophyseal hormones, such as growth hormones, adrenocorticotropin (ACTH), thyrotropin, gonadotropins, prolactin, vasopressin, and oxytocin. Concerns include radioimmunoassay, standards of thyrotropin, immunoassay of hypophyseal gonadotropins, and bioassay of prolactin. The book evaluates the assays of pancreatic hormones, such as insulin and glucagon. Chemical structure and properties of insulin and radioimmunoassay of glucagon are explained. The text also focuses on the assays of erythropoietin, renin, human chorionic gonadotropin, and human placental lactogen (HPL). Concerns include augmentation of red cell volume; biological application of renin assays; and similarities and differences between hypophyseal somatotropin and HPL. The selection is a valuable source of data for readers interested in the assays of protein and polypeptide hormones.