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Author : Thomas Peters
Publisher : Springer Science & Business Media
ISBN 13 : 3540490779
Total Pages : 317 pages
Book Rating : 4.5/5 (44 download)
Download or read book Bioactive Conformation I written by Thomas Peters and published by Springer Science & Business Media. This book was released on 2007-01-05 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Author : Thomas Peters
Publisher : Springer
ISBN 13 : 3540490809
Total Pages : 244 pages
Book Rating : 4.5/5 (44 download)
Download or read book Bioactive Conformation II written by Thomas Peters and published by Springer. This book was released on 2009-11-04 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The volume is still valid and useful after five or ten years. More information, as well as the electronic version of the whole content, is available at: springerlink.com.
Author : M. Vijayan
Publisher : Universities Press
ISBN 13 : 9788173712548
Total Pages : 828 pages
Book Rating : 4.7/5 (125 download)
Download or read book Perspectives in Structural Biology written by M. Vijayan and published by Universities Press. This book was released on 1999 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prof. G.N. Ramachandran Has Been Among The Foremost Biophysicists And Structural Biologists Of Our Times, And The Most Outstanding Scientist To Have Worked In Independent India. His Contributions Pertaining To Collagen, Methods Of Structural Analysis, Computer Modelling And Conformational Analysis, And Three-Dimensional Image Reconstruction Have Had A High Global Impact. This Volume In Honour Of Gnr Consists Of Articles At The Cutting Edge Of Structural Biology Contributed By Leading Scientists, Including Two Noble Laureates. It Is Intended To Be A Window To Modern Structural Biology And A Showcase Of The Indian Effort In This Area.
Author : Manuel Claude Peitsch
Publisher : World Scientific
ISBN 13 : 9812778772
Total Pages : 790 pages
Book Rating : 4.8/5 (127 download)
Download or read book Computational Structural Biology written by Manuel Claude Peitsch and published by World Scientific. This book was released on 2008 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work covers the impact of computational structural biology on protein structure prediction methods, macromolecular function and protein design, and key methods in drug discovery. It also addresses the computational challenges of experimental approaches in structural biology.
Author : John Matsoukas
Publisher : IOS Press
ISBN 13 : 9789051994254
Total Pages : 312 pages
Book Rating : 4.9/5 (942 download)
Download or read book Bioactive Peptides in Drug Discovery and Design written by John Matsoukas and published by IOS Press. This book was released on 1999 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: As in previous editions, the focus in ESSENTIAL MATHEMATICS with APPLICATIONS remains on the Aufmann Interactive Method (AIM). Students are encouraged to be active participants in the classroom and in their own studies as they work through the How To examples and the paired Examples and You Try It problems. Student engagement is crucial to success. Presenting students with worked examples, and then providing them with the opportunity to immediately solve similar problems, helps them build their confidence and eventually master the concepts. Simplicity is key in the organization of this edition, as in all other editions. All lessons, exercise sets, tests, and supplements are organized around a carefully constructed hierarchy of objectives. Each exercise mirrors a preceding objective, which helps to reinforce key concepts and promote skill building. This clear, objective-based approach allows students to organize their thoughts around the content, and supports instructors as they work to design syllabi, lesson plans, and other administrative documents. New features like Focus on Success, Apply the Concept, and Concept Check add an increased emphasis on study skills and conceptual understanding to strengthen the foundation of student success. The Ninth Edition also features a new design, enhancing the Aufmann Interactive Method and making the pages easier for both students and instructors to follow. Available with InfoTrac Student Collections http://gocengage.com/infotrac.
Author :
Publisher : Academic Press
ISBN 13 : 0080526721
Total Pages : 353 pages
Book Rating : 4.0/5 (85 download)
Download or read book Advances in Drug Research written by and published by Academic Press. This book was released on 1997-07-21 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets.
Author : Tommy Liljefors
Publisher : CRC Press
ISBN 13 : 9780415282888
Total Pages : 596 pages
Book Rating : 4.2/5 (828 download)
Download or read book Textbook of Drug Design and Discovery, Third Edition written by Tommy Liljefors and published by CRC Press. This book was released on 2002-07-25 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.
Author : Raimund Mannhold
Publisher : John Wiley & Sons
ISBN 13 : 3527621296
Total Pages : 502 pages
Book Rating : 4.5/5 (276 download)
Download or read book Molecular Drug Properties written by Raimund Mannhold and published by John Wiley & Sons. This book was released on 2008-06-25 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation.
Author : Camille Georges Wermuth
Publisher : Elsevier
ISBN 13 : 0080497772
Total Pages : 792 pages
Book Rating : 4.0/5 (84 download)
Download or read book The Practice of Medicinal Chemistry written by Camille Georges Wermuth and published by Elsevier. This book was released on 2003-06-11 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. - The only book available dealing with the practical aspects of medicinal chemistry - Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production - Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry
Author : Tally Naveh-Many
Publisher : Springer Science & Business Media
ISBN 13 : 0387275304
Total Pages : 211 pages
Book Rating : 4.3/5 (872 download)
Download or read book Molecular Biology of the Parathyroid written by Tally Naveh-Many and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using genetically manipulated mice. Then the biosynthetic pathway of PTH from gene ex pression to its intracellular processing and the sequences in the gene control ling its transcription as well as those regulating mRNA processing, stability and translation are described.
Author : John P. Bilezikian
Publisher : Academic Press
ISBN 13 : 0080539602
Total Pages : 1702 pages
Book Rating : 4.0/5 (85 download)
Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2002-01-19 with total page 1702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology is the essential resource for anyone involved in the study of bones. It is the most comprehensive, complete, up-to-date source of information on all aspects of bones and bone biology in one convenient source. Written and published in less than one year, it will become an indispensable resource for any scientific or medical library. This, second edition, details countless advances over the past five years, both by updating old chapters and providing additional material. It takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. The most current and timely source of information about the biology and pathology of boneProvides succinct coverage of the subjectContributors include over 200 of the most respected researchers in the fieldExtensive table of contents and index for easy referenceEasy-to-read and highly informative to both the newcomer and the initiated to the field Spans the spectrum from molecular biology to in vivo pharmacologyComplete bibliography with each entry fully referenced for additional background reading First edition was selected by Doody Publishing as one of the 250 Best Health Science books published in 1996
Author : Hiroko Satoh
Publisher : Springer Nature
ISBN 13 : 9819748283
Total Pages : 358 pages
Book Rating : 4.8/5 (197 download)
Download or read book Drug Development Supported by Informatics written by Hiroko Satoh and published by Springer Nature. This book was released on with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Elizabeth Carvajal-Millan
Publisher : CRC Press
ISBN 13 : 1000342476
Total Pages : 343 pages
Book Rating : 4.0/5 (3 download)
Download or read book Natural Food Products and Waste Recovery written by Elizabeth Carvajal-Millan and published by CRC Press. This book was released on 2021-07-09 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Food Products and Waste Recovery: Healthy Foods, Nutrition Design, and Extraction of Valuable Compounds addresses important issues in the design of functional foods and nutraceuticals, extraction of essential compounds, and food waste management. Topics in the nutrition section cover a diverse range of topics, including uses and regulations of functional foods and ingredients, supplements, nutraceuticals, and superfoods; informatics and methods in nutrition design and development; and molecular modeling techniques in food and nutrition development. The volume goes on to address properties, microstructural characteristics, and extraction techniques of bioactive compounds. Chapters also cover the use of artificial intelligence and machine learning in food waste management, mitigation, and reuse strategies for food waste. This research-based volume is a valuable reference for professionals involved in product development and researchers focusing on food products. It will be of great interest to postgraduate students and researchers in environmental policy and waste management, as well as policymakers and practitioners in consumer issues and business.
Author : Charles G. Gebelein
Publisher : Springer Science & Business Media
ISBN 13 : 1475704054
Total Pages : 698 pages
Book Rating : 4.4/5 (757 download)
Download or read book Bioactive Polymeric Systems written by Charles G. Gebelein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vast array of libraries in the world bear mute witness to the truth of the 3000-year-old observation of King Solomon who stated " ... of making many books there is no end, and much study is a weariness of the flesh." Yet books are an essential written record of our lives and the progress of science and humanity. Here is another book to add to this huge collection, but, hopefully, not just another collection of pages, but rather a book with a specific purpose to aid in alleviating the "weariness of the flesh" that could arise from much studying of other journals and books in order to obtain the basic information contained herein. This book is about polymeric materials and biological activity, as the title notes. Polymeric materials, in the broad view taken here, would include not only synthetic polymers (e.g., polyethylene, polyvinyl chloride, polyesters, polyamides, etc.), but also the natural macromolecules (e.g., proteins, nucleic acids, polysaccharides) which compose natural tissues in humans, animals and plants. In the broad sense used here, biological activity is any type of such action whether it be in medication, pest control, plant-growth regu lation, and so on. In short, this book attempts to consider, briefly, the use of any type of polymeric material system with essentially any kind of biological activity.
Author : Aman Thakur
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111434877
Total Pages : 405 pages
Book Rating : 4.1/5 (114 download)
Download or read book Computer-Aided Drug Design written by Aman Thakur and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-08-19 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer-Aided Drug Design (CADD) is a comprehensive guide designed for both beginners and experienced users in CADD. This book covers the fundamental principles and gradually delves into more advanced concepts and techniques, making it an invaluable resource to anyone interested in CADD. It begins by establishing a solid foundation, explaining the core concepts of CADD, the user interface and essential tools. It covers QSAR, molecular docking, homology modeling, virtual screening, pharmacophore modeling, ensuring that the reader can quickly become proficient in CADD. The book provides in-depth insights into 3D modeling, rendering, and parametric design. The style of the book is simple, every topic begins from the very basics and explores advanced levels with clarity. Practical examples, step-by-step tutorials and hands-on exercises, are included for better understanding.
Author : Robert Glaser
Publisher : John Wiley & Sons
ISBN 13 : 3527684212
Total Pages : 330 pages
Book Rating : 4.5/5 (276 download)
Download or read book Symmetry, Spectroscopy, and Crystallography written by Robert Glaser and published by John Wiley & Sons. This book was released on 2015-09-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in a clear and understandable manner, this book provides a comprehensive, yet non-mathematical, treatment of the topic, covering the basic principles of symmetry and the important spectroscopic techniques used to probe molecular structure. The chapters are extensively illustrated and deal with such topics as symmetry elements, operations and descriptors, symmetry guidelines, high-fidelity pseudosymmetry, crystallographic symmetry, molecular gears, and experimental techniques, including X-ray crystallography and NMR spectroscopy. As an additional feature, 3D animations of most of the structures and molecules covered are available online at wiley.com. As a result, chemists learn how to understand and predict molecular structures and reactivity. Authored by a renowned expert with numerous publications and an excellent track record in research and teaching, this is a useful source for graduate students and researchers working in the field of organic synthesis, physical chemistry, biochemistry, and crystallography, while equally serving as supplementary reading for courses on stereochemistry, organic synthesis, or crystallography.
Author : Arup Ghose
Publisher : CRC Press
ISBN 13 : 1482270765
Total Pages : 655 pages
Book Rating : 4.4/5 (822 download)
Download or read book Combinatorial Library Design and Evaluation written by Arup Ghose and published by CRC Press. This book was released on 2001-06-26 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry who offer coverage of basic principles, design strategies, methodologies, software tools and algorithms, and applications. It outlines the fundamentals of pharmacophore modelling and 3D Qua
