Bioactive Compounds From Microbes

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The Search for Bioactive Compounds from Microorganisms

Author : Satoshi Omura
Publisher : Springer Science & Business Media
ISBN 13 : 1461244129
Total Pages : 373 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis The Search for Bioactive Compounds from Microorganisms by : Satoshi Omura

Download or read book The Search for Bioactive Compounds from Microorganisms written by Satoshi Omura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery.

Bioactive Compounds from Microbes

Author : Roberto Mazzoli
Publisher : Frontiers Media SA
ISBN 13 : 2889451852
Total Pages : 144 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Bioactive Compounds from Microbes by : Roberto Mazzoli

Download or read book Bioactive Compounds from Microbes written by Roberto Mazzoli and published by Frontiers Media SA. This book was released on 2017-06-02 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microorganisms have had a long and surprising history. They were “invisible” until invention of microscope in the 17th century. Until that date, although they were extensively (but inconsciously) employed in food preservation, beer and wine fermentation, cheese, vinegar, yogurt and bread making, as well as being the causative agents of infectious diseases, they were considered as “not-existing”. The work of Pasteur in the middle of the 19th century revealed several biological activities performed by microorganisms including fermentations and pathogenicity. Due to the urgent issue to treat infectious diseases (the main cause of death at those times) the “positive potential” of the microbial world has been neglected for about one century. Once the fight against the “evil” strains was fulfilled also thanks to the antibiotics, industry began to appreciate bacteria’s beneficial characteristics and exploit selected strains as starters for both food fermentations and aroma, enzyme and texturing agent production. However, it was only at the end of the 20th century that the probiotic potential of some bacteria such as lactic acid bacteria and bifidobacteria was fully recognized. Very recently, apart from the probiotic activity of in toto bacteria, attention has begun to be directed to the chemical mediators of the probiotic effect. Thanks also to the improvement of techniques such as transcriptomics, proteomics and metabolomics, several bioactive compounds are continuously being discovered. Bioactive molecules produced by bacteria, yeasts and virus-infected cells proved to be important for improving or impairing human health. The most important result of last years’ research concerns the discovery that a very complex network of signals allows communication between organisms (from intra-species interactions to inter-kingdom signaling). Based on these findings a completely new approach has arisen: the system biology standpoind. Actually, the different organisms colonizing a certain environmental niche are not merely interacting with each other as individuals but should be considered as a whole complex ecosystem continuously exchanging information at the molecular level. In this context, this topic issue explores both antagonistic compounds (i.e. antibiotics) and “multiple function” cooperative molecules improving the physiological status of both stimulators and targets of this network. From the applicative viewpoint, these molecules could be hopefully exploited to develop new pharmaceuticals and/or nutraceuticals for improving human health.

Marine Microorganisms

Author : Leo M.L. Nollet
Publisher : CRC Press
ISBN 13 : 1315354551
Total Pages : 130 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Marine Microorganisms by : Leo M.L. Nollet

Download or read book Marine Microorganisms written by Leo M.L. Nollet and published by CRC Press. This book was released on 2016-09-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: The marine environment covers 70% of the earth’s surface and accounts for 98% of the potentially habitable space. The bioactives from marine microorganisms include antibiotic compounds, polysaccharides, inhibitors, enzymes, peptides, and pigments. These are used in various fields of biology that range from nutraceuticals to cosmeceuticals. Recent scientific investigations have revealed that marine microbial compounds exhibit various beneficial biological effects, such as anti-inflammatory, anti-cancer, anti-HIV, anti-hypertensive, and anti-diabetic. Marine Microorganisms: Extraction and Analysis of Bioactive Compounds sheds light on the extraction, clean-up, and detection methods of major compounds from marine organisms. The book includes information on the different classes of marine microorganisms and the different bioactives that can be extracted from bacteria, fungi and microalgae. Divided into 7 chapters, the book covers bioactive marine natural products, such as marine microbes, seaweeds, and marine sponges as potential sources of drug discovery, and focuses on analysis methods of the biocomponents from marine microorganisms. A useful reference tool for researchers and students, this book provides current knowledge about isolation and analysis methods of the bioactives and provides insight into the various bioactives of marine microbes toward nutraceutical and pharmaceutical development.

Bioactive Compounds from Terrestrial Extremophiles

Author : Lesley-Ann Giddings
Publisher : Springer
ISBN 13 : 3319132601
Total Pages : 95 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Bioactive Compounds from Terrestrial Extremophiles by : Lesley-Ann Giddings

Download or read book Bioactive Compounds from Terrestrial Extremophiles written by Lesley-Ann Giddings and published by Springer. This book was released on 2014-11-21 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or leads to novel drugs for human use. This SpringerBrief deals with bioactive materials from terrestrial extremophiles.

Marine Microbiology

Author : Se-Kwon Kim
Publisher : John Wiley & Sons
ISBN 13 : 3527665277
Total Pages : 558 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Marine Microbiology by : Se-Kwon Kim

Download or read book Marine Microbiology written by Se-Kwon Kim and published by John Wiley & Sons. This book was released on 2013-06-21 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues. Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.

Natural Bioactive Compounds

Author : Rajeshwar P. Sinha
Publisher : Academic Press
ISBN 13 : 0128206594
Total Pages : 502 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Natural Bioactive Compounds by : Rajeshwar P. Sinha

Download or read book Natural Bioactive Compounds written by Rajeshwar P. Sinha and published by Academic Press. This book was released on 2020-10-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)

Natural Bio-active Compounds

Author : Mohd Sayeed Akhtar
Publisher : Springer Nature
ISBN 13 : 9811371547
Total Pages : 608 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Natural Bio-active Compounds by : Mohd Sayeed Akhtar

Download or read book Natural Bio-active Compounds written by Mohd Sayeed Akhtar and published by Springer Nature. This book was released on 2019-09-06 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine. Several bioactive compounds have proved to be invaluable in mediating plant-microbe interactions, and promoting plant growth and development. Due to their numerous health-promoting properties, these compounds have been widely used as a source of medication since ancient times. However, there is an unprecedented need to meet the growing demand for natural bioactive compounds in the flavor and fragrance, food, and pharmaceutical industries. Moreover, discovering new lead molecules from natural sources is essential to overcoming the rising number of new diseases. In this regard, natural bioactive compounds hold tremendous potential for new drug discovery. Therefore, this field of research has become a vital area for researchers interested in understanding the chemistry, biosynthetic mechanisms, and pharmacological activities of these bioactive metabolites. This book describes the basics of bioactive plant compounds, their chemical properties, and their pharmacological biotechnological properties with regard to various human diseases and applications in the drug, cosmetics and herbal industries. It offers a valuable asset for all students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

Bioactive Compounds in Fermented Foods

Author : Amit Kumar Rai
Publisher : CRC Press
ISBN 13 : 042964857X
Total Pages : 511 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Bioactive Compounds in Fermented Foods by : Amit Kumar Rai

Download or read book Bioactive Compounds in Fermented Foods written by Amit Kumar Rai and published by CRC Press. This book was released on 2021-11-29 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume reviews different types of bioactive components associated with food fermentation and their impact on human health. The diversity of microorganism responsible for the production of different types of fermented foods and beverages includes bacteria, yeasts, and fungi. Biotransformation of food constituent by microorganisms occurs during fermentation processes for the production of fermented food and in the gastrointestinal tract by gut microorganisms. This biotransformation results in production of specific bioactive compounds that are responsible for a wide range of health benefits. The bioactive compounds discussed in this book includes polyphenols, bioactive peptides, fibrinolytic enzymes, gama-amino butyric acids (GABA) exopolysaccharides, probiotic, prebiotic, symbiotic and antinutritional factors. These bioactive compounds are responsible for health benefits such as antioxidant, antihypertension, antimicrobial, cholesterol lowering, anticancer, obesity and antithrombotic properties. Advanced research in the field of food fermentation and their health benefits have resulted in commercialization of some of the fermented foods as functional foods. The traditional fermented foods consumed in different parts of the world and their health benefits are discussed in detail and the book concludes with recent advances in microbial transformation during gut fermentation and their impact on human health. There has been increasing interest among researchers on the proposed title in the last decade and the book brings updated information on research and advances in different types of health benefits exhibited by bioactive compounds in a wide range of fermented foods.

Volatiles and Metabolites of Microbes

Author : Ajay Kumar
Publisher : Academic Press
ISBN 13 : 0323851649
Total Pages : 513 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Volatiles and Metabolites of Microbes by : Ajay Kumar

Download or read book Volatiles and Metabolites of Microbes written by Ajay Kumar and published by Academic Press. This book was released on 2021-06-22 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volatiles and Metabolites of Microbes compiles the latest research and advancement in the field of volatiles, metabolites synthesized from the microbial strains such as actinomycetes, bacteria, cyanobacteria, and fungal species and their potential applications in the field of healthcare issue and sustainable agriculture. There is an urgent need to explore new and advanced biological methods for health industries and sustainable agriculture and to protect the environment from environmental pollution or contaminates, global warming, and also control the health of human beings from the side effects of various pharmaceuticals products. Focusing all these factors, Volatiles and Metabolites of Microbes explores new aspects of microorganism in terms of volatiles, enzymes, bioactive compounds synthesized from the microbes and their potential applications in the field of sustainable agriculture and health-related issues Provides a broad aspect about volatiles, bioactive compounds, and secondary metabolites of microbes compiled in one cover Gives the latest research and advancement in the field of volatiles, secondary metabolites, and bioactive compounds synthesized from the different microbial strains Responds to new developments in the detection of the complex compound structures of volatiles Offers insight to a very broad audience in Biotechnology, Applied Microbiology, Agronomy, and Pathology

The Search for Bioactive Compounds from Microorganisms

Author : Satoshi Ōmura
Publisher : Springer
ISBN 13 : 9783540977551
Total Pages : 352 pages
Book Rating : 4.9/5 (775 download)

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Book Synopsis The Search for Bioactive Compounds from Microorganisms by : Satoshi Ōmura

Download or read book The Search for Bioactive Compounds from Microorganisms written by Satoshi Ōmura and published by Springer. This book was released on 1992-01-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmaceuticals from Microbes

Author : Divya Arora
Publisher : Springer
ISBN 13 : 3030046753
Total Pages : 226 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Pharmaceuticals from Microbes by : Divya Arora

Download or read book Pharmaceuticals from Microbes written by Divya Arora and published by Springer. This book was released on 2019-02-12 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the noteworthy advancement in the production of bioactive metabolites from microbes and their pharmacological significance. It highlights the pharmacological potential of marine microbes and endophytic fungi and their bioactive secondary metabolites. Emphasis is also given on the significance of probiotics and their specialized molecules in human health and disease as well as their role in dietary intervention for reducing the risk of non-alcoholic fatty liver disease. This work also serves as excellent reference material for researchers, students and academicians in the field of natural product chemistry, pharmacology and applied microbiology.

Bioprospecting of Microorganism-Based Industrial Molecules

Author : Sudhir P. Singh
Publisher : John Wiley & Sons
ISBN 13 : 1119717248
Total Pages : 452 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Bioprospecting of Microorganism-Based Industrial Molecules by : Sudhir P. Singh

Download or read book Bioprospecting of Microorganism-Based Industrial Molecules written by Sudhir P. Singh and published by John Wiley & Sons. This book was released on 2021-12-13 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance. The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader’s knowledge of the applications of different microbial diversity and reveal new avenues of research investigation. Readers will also benefit from: A thorough introduction to microbial biodiversity and bioprospecting An exploration of anti-ageing and skin lightening microbial products and microbial production of anti-cancerous biomolecules A treatment of UV protective compounds from algal biodiversity and polysaccharides from marine microalgal sources Discussions of microbial sources of insect toxic proteins and the role of microbes in bio-surfactants production Perfect for academics, scientists, researchers, graduate and post-graduate students working and studying in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology, Bioprospecting of Microorganism-Based Industrial Molecules is an indispensable guide for anyone looking for a comprehensive overview of the subject.

Biotechnological Production of Bioactive Compounds

Author : Madan L. Verma
Publisher : Elsevier
ISBN 13 : 0444643249
Total Pages : 508 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Biotechnological Production of Bioactive Compounds by : Madan L. Verma

Download or read book Biotechnological Production of Bioactive Compounds written by Madan L. Verma and published by Elsevier. This book was released on 2019-07-20 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits “bioactives’’ from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. Outlines technological advances in bioactives extraction Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules

Bioactive Compounds from Extremophiles

Author : Lesley-Ann Giddings
Publisher : Springer
ISBN 13 : 3319148362
Total Pages : 63 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Bioactive Compounds from Extremophiles by : Lesley-Ann Giddings

Download or read book Bioactive Compounds from Extremophiles written by Lesley-Ann Giddings and published by Springer. This book was released on 2015-01-07 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: This SpringerBrief sheds new light on bioactive materials from extremophiles with the focus on the biosynthesis processes and related genomics. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for human use.

Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds

Author : Yongjun Wei
Publisher : Elsevier
ISBN 13 : 0443155852
Total Pages : 273 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds by : Yongjun Wei

Download or read book Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds written by Yongjun Wei and published by Elsevier. This book was released on 2024-03-27 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many plant-derived bioactive compounds are the foundation for drugs or effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limited th Introduces the scale-up and chemical process development for microbial production of plant-derived bioactive compounds Covers the useful and effective sustainable and commercial production of plant-derived bioactive compounds Provides a guide for commercial production of plant-derived bioactive compounds and their uses for human welfare

The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition

Author : Learn-Han Lee
Publisher : Frontiers Media SA
ISBN 13 : 2889636399
Total Pages : 312 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition by : Learn-Han Lee

Download or read book The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition written by Learn-Han Lee and published by Frontiers Media SA. This book was released on 2020-03-27 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a large market demand for new drugs. The existing chronic or common ailments without cures, development of new diseases with unknown causes, and the widespread existence of antibiotic-resistant pathogens, have driven this field of research further by looking at all potential sources of natural products. To date, microbes have made a significant contribution to the health and well-being of people globally. The discoveries of useful metabolites produced by microbes have resulted in a significant proportion of pharmaceutical products in today’s market. Therefore, the investigation and identification of bioactive compound(s) producing microbes is always of great interest to researchers. Actinobacteria are one of the most important and efficient groups of natural metabolite producers. Among the numerous genera, Streptomyces have been recognized as prolific producers of useful natural compounds, as they provide more than half of the naturally-occurring antibiotics isolated to-date and continue to emerge as the primary source of new bioactive compounds. Certainly, these potentials have attracted ample research interest and a wide range of biological activities have been subsequently screened by researchers with the utilization of different In vitro and In vivo model of experiments. Literature evidence has shown that a significant number of interesting compounds produced by Actinobacteria were exhibiting either strong anticancer or neuroprotective activity. The further in depth studies have then established the modulation of apoptotic pathway was involved in those observed bioactivities. These findings indirectly prove the biopharmaceutical potential possessed by Actinobacteria and at the same time substantiate the importance of diverse pharmaceutical evaluations on Actinobacteria. In fact, many novel compounds discovered from Actinobacteria with strong potential in clinical applications have been developed into new drugs by pharmaceutical companies. Together with the advancement in science and technology, it is predicted that there would be an expedition in discoveries of new bioactive compounds producing Actinobacteria from various sources, including soil and marine sources. In light of these current needs, and great interest in the scope of this research, this book seeks to contribute on the investigation of different biological active compound(s) producing actinobacteria which are exhibiting antimicrobial, antioxidant, neuroprotective, anticancer activities and similar.

Bioactive Natural products in Drug Discovery

Author : Joginder Singh
Publisher : Springer Nature
ISBN 13 : 9811513945
Total Pages : 733 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Bioactive Natural products in Drug Discovery by : Joginder Singh

Download or read book Bioactive Natural products in Drug Discovery written by Joginder Singh and published by Springer Nature. This book was released on 2020-04-30 with total page 733 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.