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Benzodiazepines Ii
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Book Synopsis Benzodiazepines II by : Harald Schütz
Download or read book Benzodiazepines II written by Harald Schütz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: " ... this is an excellent compilation of data which should be on the bookshelves of all analysts interested in the benzodiazepines. It is to be hoped that, with the introduction of so many new ben zodiazepines, the author will quickly add these in a second edi tion" (A. C. Moffat in: Trends in Analytical Chemistry, 1983). This review, deputizing for many others, reflects the friendly reception enjoyed by the first volume of Benzodiazepines, which was published in 1982 and apparently closed a gap in the ben zodiazepine literature. In the meantime, Benzodiazepines has established itself as a standard book, as evidenced by numerous letters and quotations. Suggestions were also soon made for a new edition in view of the unusually rapid development in the field of the benzodiazepines. It became quickly obvious, however, that it would not be sufficient to publish a revised second edition, but that a completely new second volume would be required for which, however, the successful previous format could be largely retained. The following considerations seem worth mentioning in connection with the preparation of Volume II: - To ensure continuity with Volume I as far as possible, the list of references was consecutively numbered (references 1 to 3779 in Volume I, references 3780 to 11338 in Volume II). Whereas in Vol. I the substances appear in the sequential order of their historical development they are listed in alphabetical order in Vol. II.
Download or read book Benzodiazepines written by H. Schütz and published by Springer. This book was released on 2011-11-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: To comment at length on the importance of the benzodiazepines seems superfluous within the scope of this preface. No other class of active substances has experienced an even approximately compa rable advance in the past two decades. It is therefore not surprising that the formerly dominant barbiturates and bromocarbamides have had to give way in many fields to the benzodiazepines, which now rank first (Proudfoot and Park [1828]). Closely linked with the great therapeutic importance of the benzodia zepines are analytical problems. Detection and the determination of blood levels can be necessary under therapeutic aspects, for instance in working out optimally effective levels in the treatment of epileptic conditions ("drug monitoring"), but also in connection with questions at issue in toxicology and traffic medicine. A toxicological analysis can be subdivided into the following steps: Detection (identification including screening) Determination (e. g. blood, plasma or serum levels) Interpretation of the analytical results. This book is intended as a contribution to each of these chapters: The part "Analytical Data" (pp.I-122) gives a comprehensive collec tion of data, e.g. general and chromatographic data (TLC, GLC) as well as spectra (UV, IR, MS) of 19 commercial preparations, 23 important metabolites and 18 hydrolysis derivatives. Information about biotransformation and the possible formation of aminobenzo phenone derivatives is also given. The most important analytical methods are presented in an extensive review on pp.123-204 in order to make it possible to select the optimum method on the basis of the essential data.
Book Synopsis Advances in Patient Safety by : Kerm Henriksen
Download or read book Advances in Patient Safety written by Kerm Henriksen and published by . This book was released on 2005 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: v. 1. Research findings -- v. 2. Concepts and methodology -- v. 3. Implementation issues -- v. 4. Programs, tools and products.
Book Synopsis Pain Modulation by : Howard L. Fields
Download or read book Pain Modulation written by Howard L. Fields and published by Elsevier Publishing Company. This book was released on 1988-01-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.
Book Synopsis Seminars in Addiction Psychiatry by : Ed Day
Download or read book Seminars in Addiction Psychiatry written by Ed Day and published by Cambridge University Press. This book was released on 2021-11-04 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive coverage of the theory, practical understanding and management of the psychiatric aspects of drug and alcohol use and dependence.
Book Synopsis Molecular Aspects of Anticancer Drug DNA Interactions by : Stephen Neidle
Download or read book Molecular Aspects of Anticancer Drug DNA Interactions written by Stephen Neidle and published by CRC Press. This book was released on 1994-05-03 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.
Download or read book Versed written by Rae Armantrout and published by Wesleyan University Press. This book was released on 2010-08 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A collection of poetry organized in two sections. The first section, "Versed," play with vice and versa, the perversity of human consciousness. They flirt with error and delusion, skating on a thin ice that inevitably cracks. The second section, "Dark Matter," alludes to more than the unseen substance thought to make up the majority of mass in the universe. The invisible and unknowable are confronted directly as the author's experience with cancer marks these poems with a new austerity, shot through with her signature wit and stark unsentimental thinking."--Résumé de l'éditeur.
Download or read book Death Grip written by Matt Samet and published by St. Martin's Press. This book was released on 2013-02-12 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Death Grip chronicles a top climber's near-fatal struggle with anxiety and depression, and his nightmarish journey through the dangerous world of prescription drugs. Matt Samet lived to climb, and craved the challenge, risk, and exhilaration of conquering sheer rock faces around the United States and internationally. But Samet's depression, compounded by the extreme diet and fitness practices of climbers, led him to seek professional help. He entered the murky, inescapable world of psychiatric medicine, where he developed a dangerous addiction to prescribed medications—primarily "benzos," or benzodiazepines—that landed him in institutions and nearly killed him. With dramatic storytelling, persuasive research data, and searing honesty, Matt Samet reveals the hidden epidemic of benzo addiction, which some have suggested can be harder to quit than heroin. Millions of adults and teenagers are prescribed these drugs, but few understand how addictive they are—and how dangerous long-term usage can be, even when prescribed by doctors. After a difficult struggle with addiction, Samet slowly makes his way to a life in recovery through perseverance and a deep love of rock climbing. Conveying both the exhilaration of climbing in the wilderness and the utter madness of addiction, Death Grip is a powerful and revelatory memoir.
Download or read book Benzodiazepines written by H. Schütz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: To comment at length on the importance of the benzodiazepines seems superfluous within the scope of this preface. No other class of active substances has experienced an even approximately compa rable advance in the past two decades. It is therefore not surprising that the formerly dominant barbiturates and bromocarbamides have had to give way in many fields to the benzodiazepines, which now rank first (Proudfoot and Park [1828]). Closely linked with the great therapeutic importance of the benzodia zepines are analytical problems. Detection and the determination of blood levels can be necessary under therapeutic aspects, for instance in working out optimally effective levels in the treatment of epileptic conditions ("drug monitoring"), but also in connection with questions at issue in toxicology and traffic medicine. A toxicological analysis can be subdivided into the following steps: Detection (identification including screening) Determination (e. g. blood, plasma or serum levels) Interpretation of the analytical results. This book is intended as a contribution to each of these chapters: The part "Analytical Data" (pp.I-122) gives a comprehensive collec tion of data, e.g. general and chromatographic data (TLC, GLC) as well as spectra (UV, IR, MS) of 19 commercial preparations, 23 important metabolites and 18 hydrolysis derivatives. Information about biotransformation and the possible formation of aminobenzo phenone derivatives is also given. The most important analytical methods are presented in an extensive review on pp.123-204 in order to make it possible to select the optimum method on the basis of the essential data.
Book Synopsis The Benzodiazepines Crisis by : John Peppin
Download or read book The Benzodiazepines Crisis written by John Peppin and published by Oxford University Press, USA. This book was released on 2021 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Nevertheless, these negative aspects have yet to be thoroughly addressed within the medical community and remain virtually unknown to patients. This book offers an in-depth discussion of the downsides of this overused class of drugs and calls for their rational and dramatically reduced usage.
Book Synopsis Handbook of Drug Interactions by : Ashraf Mozayani
Download or read book Handbook of Drug Interactions written by Ashraf Mozayani and published by Springer Science & Business Media. This book was released on 2003-10-15 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309459575 Total Pages :483 pages Book Rating :4.3/5 (94 download)
Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine
Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Author :Salvatore J. Salamone Publisher :Springer Science & Business Media ISBN 13 :1592591094 Total Pages :157 pages Book Rating :4.5/5 (925 download)
Book Synopsis Benzodiazepines and GHB by : Salvatore J. Salamone
Download or read book Benzodiazepines and GHB written by Salvatore J. Salamone and published by Springer Science & Business Media. This book was released on 2001-09-14 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent experts explain the pharmacology and metabolism of benzodiazepines (LDB) and g-hydroxybutyric acid (GHB) and offer powerful and effective methodologies that will enable better detection of these drugs in various body fluids, as well as in hair. The techniques include highly sensitive immunoassay detection of LDBs, the detection of Rohypnol® and other LDBs by mass spectrometry, and the ultrasensitive detection of GHB. State-of-the-art and highly practical, Benzodiazepines and GHB: Detection and Pharmacology offers toxicologists, forensic scientists, and clinical chemists today's most effective methods for detecting these widely abused drugs that are sometimes found associated with criminal acts.
Book Synopsis Equine Anesthesia by : William W. Muir III
Download or read book Equine Anesthesia written by William W. Muir III and published by Elsevier Health Sciences. This book was released on 2008-12-18 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: All veterinary team members involved in the everyday care of horses that require anesthesia or special emergency care will benefit from this reliable and inclusive resource. This text provides all of the information needed to prepare, conduct, and monitor the administration of drugs in order to produce safe and effective anesthesia, treat pain, respond to adverse effects, and perform and monitor emergency and critical care treatment. It is the most comprehensive and detailed book available on these subjects, addressing the needs and concerns of practitioners in both hospital and field settings. Discusses all aspects of equine anesthesia, including history, physiology, pharmacology, drug dosages, patient preparation, induction-maintenance-recovery of anesthesia management of potential complications, and more. Provides a detailed review of the respiratory and cardiovascular physiology of the horse. Provides thorough coverage of preoperative pain management in horses. Covers emergency medical care and managing anesthetic complications in both hospital and field situations. Includes information on the latest anesthetic drugs, including safe and effective protocols for different procedures, and the most up-to-date monitoring techniques. Each contributor is a recognized expert in his or her respective equine specialty, renowned for clinical as well as academic and research expertise. A complete update of all drug information and pain management techniques. The very latest research findings and clinical applications of anesthetic agents and techniques. The most recent developments in post-anesthetic care and monitoring. A chapter on intravenous anesthetic and analgesic adjuncts to inhalation anesthesia. A chapter on anesthesia and analgesia for donkeys and mules. A chapter on perioperative pain management. Many new illustrations as well as tables, graphs, boxes, key points, and summaries that make information instantly accessible.
Book Synopsis Progress in drug research. 50.1998 by : Ernst Jucker
Download or read book Progress in drug research. 50.1998 written by Ernst Jucker and published by Springer Science & Business Media. This book was released on 1998 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Drug Research is a prestigious book series (founded in 1959) which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmalogical research. Each volume contains fully cross-referencing indexes which link the volumes together, forming a virtually encyclopaedic work. The series thus serves as an important, time-saving source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines. Volume 50 in the series includes: P.N. Kaul: Drug discovery: Past, present and future M. Rohmer: Isoprenoid biosynthesis via the mevalonate -- independent route, a novel target for antibacterial drugs G. Edwards and A.H. Weston: Endothelium, -derived hyperpolarizing factor -- a critical appraisal R.W. Rockhold: Glutamatic involvement in psychomotor stimulant action J.M. Colacino and K.A. Staschke: The identification and development of antiviral agents for the treatment of chronic hepatitis B virus infection T.D. Johnson: Polyamines and cerebral ischemia
Download or read book Blitzed written by Norman Ohler and published by HarperCollins. This book was released on 2017-03-07 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times bestseller, Norman Ohler's Blitzed is a "fascinating, engrossing, often dark history of drug use in the Third Reich” (Washington Post). The Nazi regime preached an ideology of physical, mental, and moral purity. Yet as Norman Ohler reveals in this gripping history, the Third Reich was saturated with drugs: cocaine, opiates, and, most of all, methamphetamines, which were consumed by everyone from factory workers to housewives to German soldiers. In fact, troops were encouraged, and in some cases ordered, to take rations of a form of crystal meth—the elevated energy and feelings of invincibility associated with the high even help to account for the breakneck invasion that sealed the fall of France in 1940, as well as other German military victories. Hitler himself became increasingly dependent on injections of a cocktail of drugs—ultimately including Eukodal, a cousin of heroin—administered by his personal doctor. Thoroughly researched and rivetingly readable, Blitzed throws light on a history that, until now, has remained in the shadows. “Delightfully nuts.”—The New Yorker
Book Synopsis The Ashton Manual (Revised) by : Prof Ashton
Download or read book The Ashton Manual (Revised) written by Prof Ashton and published by Blurb. This book was released on 2024-04-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication presents insights into the impacts of benzodiazepines on both the mind and body, elucidating the mechanisms through which these effects manifest. It offers comprehensive guidance on safely discontinuing usage following extended periods, furnishing tailored tapering plans for various benzodiazepines. The text delves into withdrawal symptoms, both immediate and prolonged, elucidating their underlying causes and strategies for managing them. Ultimately, the overarching message underscores the potential for successful withdrawal among most long-term benzodiazepine users, leading to enhanced well-being and contentment.
