Behavioral Neurogenetics

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Behavioral Neurogenetics

Author : John F. Cryan
Publisher : Springer Science & Business Media
ISBN 13 : 3642278590
Total Pages : 637 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Behavioral Neurogenetics by : John F. Cryan

Download or read book Behavioral Neurogenetics written by John F. Cryan and published by Springer Science & Business Media. This book was released on 2012-05-04 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental disorders. The importance of gene-environment interactions is emphasised and the role of neuroimaging in unravelling the functional consequences of genetic variability described. This volume will be valued by both the basic scientist and clinician alike who may use it as a detailed reference book. It will also be of use to the novice to the field, to whom it will serve as an in-depth introduction to this exciting area of research.

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Author : Robert T. Gerlai
Publisher : Academic Press
ISBN 13 : 0128041161
Total Pages : 710 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research by : Robert T. Gerlai

Download or read book Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research written by Robert T. Gerlai and published by Academic Press. This book was released on 2018-04-24 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials - Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior - Written and edited by leading international experts

Behavioral and Neural Genetics of Zebrafish

Author : Robert T. Gerlai
Publisher : Academic Press
ISBN 13 : 9780128175286
Total Pages : 800 pages
Book Rating : 4.1/5 (752 download)

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Book Synopsis Behavioral and Neural Genetics of Zebrafish by : Robert T. Gerlai

Download or read book Behavioral and Neural Genetics of Zebrafish written by Robert T. Gerlai and published by Academic Press. This book was released on 2020-04 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has seen a rapid accumulation of knowledge on the behavioral characteristics of zebrafish, and increased investigation into the neurobiological basis of behavior using zebrafish. This simple vertebrate represents an ideal compromise between system complexity and practical simplicity, with its mammalian sequence homology, fecundity, and conveniently small size and transparent embryology. Behavioral and Neural Genetics of Zebrafish assembles state of the art methodologies and the most current concepts pertinent to the neurobehavioral genetics of zebrafish. Discussing its natural behavior, motor function, and learning and memory, it focuses on the fry and adult zebrafish and features a comprehensive account of modern genetic and neural methods adapted to or specifically developed for Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish will be presented, as well as a section on bioinformatics and "big-data" related questions. Focusing on this excellent translational tool, this book examines a species with which investigators may model and analyze even such complex human diseases as those associated with brain dysfunction. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes description of behavioral, genetic, and neural methods and concepts and adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics

Behavioral Genetics of the Fly (Drosophila Melanogaster)

Author : Josh Dubnau
Publisher : Cambridge University Press
ISBN 13 : 1107009030
Total Pages : 309 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Behavioral Genetics of the Fly (Drosophila Melanogaster) by : Josh Dubnau

Download or read book Behavioral Genetics of the Fly (Drosophila Melanogaster) written by Josh Dubnau and published by Cambridge University Press. This book was released on 2014-06-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.

Behavioral Genetics of the Mouse

Author : Wim E. Crusio
Publisher : Cambridge University Press
ISBN 13 : 1107044456
Total Pages : 471 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Behavioral Genetics of the Mouse by : Wim E. Crusio

Download or read book Behavioral Genetics of the Mouse written by Wim E. Crusio and published by Cambridge University Press. This book was released on 2014-09-25 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and critical overview of the major genetically modified mouse lines used to model human neurobehavioral disorders.

Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes

Author : Wim E. Crusio
Publisher : Cambridge University Press
ISBN 13 : 1107034817
Total Pages : 361 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes by : Wim E. Crusio

Neurobehavioral Genetics

Author : Byron C. Jones
Publisher : CRC Press
ISBN 13 : 1420003569
Total Pages : 522 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neurobehavioral Genetics by : Byron C. Jones

Download or read book Neurobehavioral Genetics written by Byron C. Jones and published by CRC Press. This book was released on 2006-08-30 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. International researchers incorporate several new developments in the field, including: De

Principles of Behavioral Genetics

Author : Robert R.H. Anholt
Publisher : Academic Press
ISBN 13 : 0080919898
Total Pages : 345 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Principles of Behavioral Genetics by : Robert R.H. Anholt

Download or read book Principles of Behavioral Genetics written by Robert R.H. Anholt and published by Academic Press. This book was released on 2009-09-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Behavioral Genetics provides an introduction to the fascinating science that aims to understand how our genes determine what makes us tick. It presents a comprehensive overview of the relationship between genes, brain, and behavior. Introductory chapters give clear explanations of basic processes of the nervous system and fundamental principles of genetics of complex traits without excessive statistical jargon. Individual chapters describe the genetics of social interactions, olfaction and taste, memory and learning, circadian behavior, locomotion, sleep, and addiction, as well as the evolution of behavior. Whereas the focus is on genetics, neurobiological and ecological aspects are also included to provide intellectual breadth. The book uses examples that span the gamut from classical model organisms to non-model systems and human biology, and include both laboratory and field studies. Samples of historical information accentuate the text to provide the reader with an appreciation of the history of the field. This book will be a valuable resource for future generations of scientists who focus on the field of behavioral genetics. - Defines the emerging science of behavioral genetics - Engagingly written by two leading experts in behavioral genetics - Clear explanations of basic quantitative genetic, neurogenetic and genomic applications to the study of behavior - Numerous examples ranging from model organisms to non-model systems and humans - Concise overviews and summaries for each chapter

Handbook of Molecular-Genetic Techniques for Brain and Behavior Research

Author : Wim E. Crusio
Publisher : Elsevier
ISBN 13 : 0080536867
Total Pages : 994 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of Molecular-Genetic Techniques for Brain and Behavior Research by : Wim E. Crusio

Download or read book Handbook of Molecular-Genetic Techniques for Brain and Behavior Research written by Wim E. Crusio and published by Elsevier. This book was released on 1999-10-18 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.

Behavior Genetics of Cognition Across the Lifespan

Author : Deborah Finkel
Publisher : Springer Science & Business Media
ISBN 13 : 1461474477
Total Pages : 306 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Behavior Genetics of Cognition Across the Lifespan by : Deborah Finkel

Download or read book Behavior Genetics of Cognition Across the Lifespan written by Deborah Finkel and published by Springer Science & Business Media. This book was released on 2013-07-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Along with psychopathology, cognition has been one of the primary phenotypic focal points of the field of behavior genetics since its inception. Francis Galton’s 1874 examination of eminent families in Britain was among the earliest attempts to investigate whether cognitive achievements run in families. This volume presents current methodologies for understanding cognitive abilities that move beyond the outdated nature vs. nurture paradigm. Recent advances in both collection and statistical modeling of twin data, particularly longitudinal twin data, make this an especially advantageous moment to produce a work that presents a collection of the groundbreaking research on cognitive abilities across the lifespan. This volume presents an overview of the current state of quantitative and molecular genetic investigations into the many facets of cognitive performance and functioning across the lifespan.

Misbehaving Science

Author : Aaron Panofsky
Publisher : University of Chicago Press
ISBN 13 : 022605859X
Total Pages : 334 pages
Book Rating : 4.2/5 (26 download)

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Book Synopsis Misbehaving Science by : Aaron Panofsky

Download or read book Misbehaving Science written by Aaron Panofsky and published by University of Chicago Press. This book was released on 2014-07-07 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavior genetics has always been a breeding ground for controversies. From the “criminal chromosome” to the “gay gene,” claims about the influence of genes like these have led to often vitriolic national debates about race, class, and inequality. Many behavior geneticists have encountered accusations of racism and have had their scientific authority and credibility questioned, ruining reputations, and threatening their access to coveted resources. In Misbehaving Science, Aaron Panofsky traces the field of behavior genetics back to its origins in the 1950s, telling the story through close looks at five major controversies. In the process, Panofsky argues that persistent, ungovernable controversy in behavior genetics is due to the broken hierarchies within the field. All authority and scientific norms are questioned, while the absence of unanimously accepted methods and theories leaves a foundationless field, where disorder is ongoing. Critics charge behavior geneticists with political motivations; champions say they merely follow the data where they lead. But Panofsky shows how pragmatic coping with repeated controversies drives their scientific actions. Ironically, behavior geneticists’ struggles for scientific authority and efforts to deal with the threats to their legitimacy and autonomy have made controversy inevitable—and in some ways essential—to the study of behavior genetics.

Animal Models of Behavior Genetics

Author : Jonathan C. Gewirtz
Publisher : Springer
ISBN 13 : 1493937774
Total Pages : 395 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Animal Models of Behavior Genetics by : Jonathan C. Gewirtz

Download or read book Animal Models of Behavior Genetics written by Jonathan C. Gewirtz and published by Springer. This book was released on 2016-08-10 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis of mental illness. Included in the coverage: Mating and fighting in Drosophila. Attachment and social bonding. Impulsivity in rodents and humans. Animal models of cognitive decline. Animal models of social cognition. Future directions for animal models in behavioral genetics. A detailed map of where this evolving field is headed, Animal Models of Behavior Genetics shows geneticists, molecular biologists, and cognitive neuroscientists paths beyond established concepts toward a more knowledgeable and collaborative future.

Neuroimaging Genetics

Author : Kristin L. Bigos
Publisher : Oxford University Press
ISBN 13 : 0190209771
Total Pages : 433 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Neuroimaging Genetics by : Kristin L. Bigos

Download or read book Neuroimaging Genetics written by Kristin L. Bigos and published by Oxford University Press. This book was released on 2016-02-03 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of neuroimaging genetics has grown exponentially over the past decade. To date there are more than 10,000 published papers involving MRI, PET, MEG and genetics. Neuroimaging Genetics: Principles and Practices is the comprehensive volume edited by Drs. Bigos, Hariri, and Weinberger and co-authored by the preeminent scholars in the field. This text reviews the basic principles of neuroimaging techniques and their application to neuroimaging genetics. The work presented in this volume elaborates on the explosive interest from diverse research areas in psychiatry and neurology in the use of imaging genetics as a unique tool to establish and identify mechanisms of risk, establish biological significance, and extend statistical evidence of genetic associations. Examples throughout highlight the application of imaging genetics to understand neurochemical systems and pathways, explore relationships between genetics and the structural and functional connectivity in human brain, and provide insight into mechanisms of risk for psychiatric and neurologic illness.

Advances in Genetics

Author :
Publisher : Academic Press
ISBN 13 : 0080922392
Total Pages : 263 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Advances in Genetics by :

Download or read book Advances in Genetics written by and published by Academic Press. This book was released on 2011-09-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics research. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

Encyclopedia of the Human Brain

Author :
Publisher : Elsevier
ISBN 13 : 0080548032
Total Pages : 3607 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Encyclopedia of the Human Brain by :

Download or read book Encyclopedia of the Human Brain written by and published by Elsevier. This book was released on 2002-07-04 with total page 3607 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, enormous strides have been made in understanding the human brain. The advent of sophisticated new imaging techniques (e.g. PET, MRI, MEG, etc.) and new behavioral testing procedures have revolutionized our understanding of the brain, and we now know more about the anatomy, functions, and development of this organ than ever before. However, much of this knowledge is scattered across scientific journals and books in a diverse group of specialties: psychology, neuroscience, medicine, etc. The Encyclopedia of the Human Brain places all information in a single source and contains clearly written summaries on what is known of the human brain. Covering anatomy, physiology, neuropsychology, clinical neurology, neuropharmacology, evolutionary biology, genetics, and behavioral science, this four-volume encyclopedia contains over 200 peer reviewed signed articles from experts around the world. The Encyclopedia articles range in size from 5-30 printed pages each, and contain a definition paragraph, glossary, outline, and suggested readings, in addition to the body of the article. Lavishly illustrated, the Encyclopedia includes over 1000 figures, many in full color. Managing both breadth and depth, the Encyclopedia is a must-have reference work for life science libraries and researchers investigating the human brain.

Behavioral Genetics

Author : Robert Plomin
Publisher : Macmillan
ISBN 13 :
Total Pages : 568 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Behavioral Genetics by : Robert Plomin

Download or read book Behavioral Genetics written by Robert Plomin and published by Macmillan. This book was released on 2008-02-22 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of human and animal behavioral genetics and examines the crossroads where the fields of psychology, psychiatry, and genetics intersect.

Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes

Author : Wim E. Crusio
Publisher : Cambridge University Press
ISBN 13 : 1107355575
Total Pages : 361 pages
Book Rating : 4.1/5 (73 download)

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Book Synopsis Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes by : Wim E. Crusio

Download or read book Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes written by Wim E. Crusio and published by Cambridge University Press. This book was released on 2013-04-25 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.