Bayesian Biostatistics

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Publisher : John Wiley & Sons
ISBN 13 : 0470018232
Total Pages : 544 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Bayesian Biostatistics by : Emmanuel Lesaffre

Download or read book Bayesian Biostatistics written by Emmanuel Lesaffre and published by John Wiley & Sons. This book was released on 2012-08-13 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growth of biostatistics has been phenomenal in recent years and has been marked by considerable technical innovation in both methodology and computational practicality. One area that has experienced significant growth is Bayesian methods. The growing use of Bayesian methodology has taken place partly due to an increasing number of practitioners valuing the Bayesian paradigm as matching that of scientific discovery. In addition, computational advances have allowed for more complex models to be fitted routinely to realistic data sets. Through examples, exercises and a combination of introductory and more advanced chapters, this book provides an invaluable understanding of the complex world of biomedical statistics illustrated via a diverse range of applications taken from epidemiology, exploratory clinical studies, health promotion studies, image analysis and clinical trials. Key Features: Provides an authoritative account of Bayesian methodology, from its most basic elements to its practical implementation, with an emphasis on healthcare techniques. Contains introductory explanations of Bayesian principles common to all areas of application. Presents clear and concise examples in biostatistics applications such as clinical trials, longitudinal studies, bioassay, survival, image analysis and bioinformatics. Illustrated throughout with examples using software including WinBUGS, OpenBUGS, SAS and various dedicated R programs. Highlights the differences between the Bayesian and classical approaches. Supported by an accompanying website hosting free software and case study guides. Bayesian Biostatistics introduces the reader smoothly into the Bayesian statistical methods with chapters that gradually increase in level of complexity. Master students in biostatistics, applied statisticians and all researchers with a good background in classical statistics who have interest in Bayesian methods will find this book useful.

Bayesian Biostatistics and Diagnostic Medicine

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Publisher : CRC Press
ISBN 13 : 1584887680
Total Pages : 214 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis Bayesian Biostatistics and Diagnostic Medicine by : Lyle D. Broemeling

Download or read book Bayesian Biostatistics and Diagnostic Medicine written by Lyle D. Broemeling and published by CRC Press. This book was released on 2007-07-12 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are numerous advantages to using Bayesian methods in diagnostic medicine, which is why they are employed more and more today in clinical studies. Exploring Bayesian statistics at an introductory level, Bayesian Biostatistics and Diagnostic Medicine illustrates how to apply these methods to solve important problems in medicine and biology.

Bayesian Thinking in Biostatistics

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Publisher : CRC Press
ISBN 13 : 1000352943
Total Pages : 622 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Bayesian Thinking in Biostatistics by : Gary L Rosner

Download or read book Bayesian Thinking in Biostatistics written by Gary L Rosner and published by CRC Press. This book was released on 2021-03-15 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for Bayesian Thinking in Biostatistics: "This thoroughly modern Bayesian book ...is a 'must have' as a textbook or a reference volume. Rosner, Laud and Johnson make the case for Bayesian approaches by melding clear exposition on methodology with serious attention to a broad array of illuminating applications. These are activated by excellent coverage of computing methods and provision of code. Their content on model assessment, robustness, data-analytic approaches and predictive assessments...are essential to valid practice. The numerous exercises and professional advice make the book ideal as a text for an intermediate-level course..." -Thomas Louis, Johns Hopkins University "The book introduces all the important topics that one would usually cover in a beginning graduate level class on Bayesian biostatistics. The careful introduction of the Bayesian viewpoint and the mechanics of implementing Bayesian inference in the early chapters makes it a complete self- contained introduction to Bayesian inference for biomedical problems....Another great feature for using this book as a textbook is the inclusion of extensive problem sets, going well beyond construed and simple problems. Many exercises consider real data and studies, providing very useful examples in addition to serving as problems." - Peter Mueller, University of Texas With a focus on incorporating sensible prior distributions and discussions on many recent developments in Bayesian methodologies, Bayesian Thinking in Biostatistics considers statistical issues in biomedical research. The book emphasizes greater collaboration between biostatisticians and biomedical researchers. The text includes an overview of Bayesian statistics, a discussion of many of the methods biostatisticians frequently use, such as rates and proportions, regression models, clinical trial design, and methods for evaluating diagnostic tests. Key Features Applies a Bayesian perspective to applications in biomedical science Highlights advances in clinical trial design Goes beyond standard statistical models in the book by introducing Bayesian nonparametric methods and illustrating their uses in data analysis Emphasizes estimation of biomedically relevant quantities and assessment of the uncertainty in this estimation Provides programs in the BUGS language, with variants for JAGS and Stan, that one can use or adapt for one's own research The intended audience includes graduate students in biostatistics, epidemiology, and biomedical researchers, in general Authors Gary L. Rosner is the Eli Kennerly Marshall, Jr., Professor of Oncology at the Johns Hopkins School of Medicine and Professor of Biostatistics at the Johns Hopkins Bloomberg School of Public Health. Purushottam (Prakash) W. Laud is Professor in the Division of Biostatistics, and Director of the Biostatistics Shared Resource for the Cancer Center, at the Medical College of Wisconsin. Wesley O. Johnson is professor Emeritus in the Department of Statistics as the University of California, Irvine.

Bayesian Biostatistics

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Publisher : CRC Press
ISBN 13 : 9780367401399
Total Pages : 704 pages
Book Rating : 4.4/5 (13 download)

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Book Synopsis Bayesian Biostatistics by : Donald a Berry

Download or read book Bayesian Biostatistics written by Donald a Berry and published by CRC Press. This book was released on 2019-08-30 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides descriptions, explanations and examples of the Bayesian approach to statistics, demonstrating the utility of Bayesian methods for analyzing real-world problems in the health sciences. The work considers the individual components of Bayesian analysis.;College or university bookstores may order five or more copies at a special student price, available on request from Marcel Dekker, Inc.

Elementary Bayesian Biostatistics

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Publisher : CRC Press
ISBN 13 : 1584887257
Total Pages : 400 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis Elementary Bayesian Biostatistics by : Lemuel A. Moye

Download or read book Elementary Bayesian Biostatistics written by Lemuel A. Moye and published by CRC Press. This book was released on 2016-04-19 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian analyses have made important inroads in modern clinical research due, in part, to the incorporation of the traditional tools of noninformative priors as well as the modern innovations of adaptive randomization and predictive power. Presenting an introductory perspective to modern Bayesian procedures, Elementary Bayesian Biostatistics explo

Biostatistics

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Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Biostatistics by : George G. Woodworth

Download or read book Biostatistics written by George G. Woodworth and published by Wiley-Interscience. This book was released on 2004-09-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential introductory text linking traditional biostatistics with bayesian methods In recent years, Bayesian methods have seen an explosion of interest, with applications in fields including biochemistry, ecology, medicine, oncology, pharmacology, and public health. As an interpretive system integrating data with observation, the Bayesian approach provides a nuanced yet mathematically rigorous means of conceptualizing biomedical statistics–from diagnostic tests to DNA evidence. Biostatistics: A Bayesian Introduction offers a pioneering approach by presenting the foundations of biostatistics through the Bayesian lens. Using easily understood, classic Dutch Book thought experiments to derive subjective probability from a simple principle of rationality, the book connects statistical science with scientific reasoning. The author shows how to compute, interpret, and report Bayesian statistical analyses in practice, and illustrates how to reinterpret traditional statistical reporting–such as confidence intervals, margins of error, and one-sided p-values–in Bayesian terms. Topics covered include: Probability and subjective probability Distributions and descriptive statistics Continuous probability distributions Comparing rates and means Linear models and statistical adjustment Logistic regression and adjusted odds ratios Survival analysis Hierarchical models and meta-analysis Decision theory and sample size determination The book includes extensive problem sets and references in each chapter, as well as complete instructions on computer analysis with the versatile SAS and WinBUGS software packages as well as the Excel spreadsheet program. For professionals and students, Biostatistics: A Bayesian Introduction offers an unique, real-world entry point into a remarkable alternative method of interpreting statistical data.

Bayesian Analysis Made Simple

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Publisher : CRC Press
ISBN 13 : 1439839549
Total Pages : 366 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bayesian Analysis Made Simple by : Phil Woodward

Download or read book Bayesian Analysis Made Simple written by Phil Woodward and published by CRC Press. This book was released on 2011-08-26 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the popularity of the Bayesian approach to statistics has been growing for years, many still think of it as somewhat esoteric, not focused on practical issues, or generally too difficult to understand. Bayesian Analysis Made Simple is aimed at those who wish to apply Bayesian methods but either are not experts or do not have the time to create WinBUGS code and ancillary files for every analysis they undertake. Accessible to even those who would not routinely use Excel, this book provides a custom-made Excel GUI, immediately useful to those users who want to be able to quickly apply Bayesian methods without being distracted by computing or mathematical issues. From simple NLMs to complex GLMMs and beyond, Bayesian Analysis Made Simple describes how to use Excel for a vast range of Bayesian models in an intuitive manner accessible to the statistically savvy user. Packed with relevant case studies, this book is for any data analyst wishing to apply Bayesian methods to analyze their data, from professional statisticians to statistically aware scientists.

Bayesian Adaptive Methods for Clinical Trials

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Publisher : CRC Press
ISBN 13 : 1439825513
Total Pages : 316 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bayesian Adaptive Methods for Clinical Trials by : Scott M. Berry

Download or read book Bayesian Adaptive Methods for Clinical Trials written by Scott M. Berry and published by CRC Press. This book was released on 2010-07-19 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti

Bayesian Methods for Measures of Agreement

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Publisher : CRC Press
ISBN 13 : 1420083430
Total Pages : 350 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Bayesian Methods for Measures of Agreement by : Lyle D. Broemeling

Download or read book Bayesian Methods for Measures of Agreement written by Lyle D. Broemeling and published by CRC Press. This book was released on 2009-01-12 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process.The author employs a Bayesian approach to provide statistical inferences

Bayesian Methods in Epidemiology

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Publisher : CRC Press
ISBN 13 : 1466564989
Total Pages : 464 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Bayesian Methods in Epidemiology by : Lyle D. Broemeling

Download or read book Bayesian Methods in Epidemiology written by Lyle D. Broemeling and published by CRC Press. This book was released on 2013-08-13 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a biostatistics expert with over 20 years of experience in the field, Bayesian Methods in Epidemiology presents statistical methods used in epidemiology from a Bayesian viewpoint. It employs the software package WinBUGS to carry out the analyses and offers the code in the text and for download online.The book examines study designs that

Bayesian Methods in Pharmaceutical Research

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Publisher : CRC Press
ISBN 13 : 1351718673
Total Pages : 547 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Bayesian Methods in Pharmaceutical Research by : Emmanuel Lesaffre

Download or read book Bayesian Methods in Pharmaceutical Research written by Emmanuel Lesaffre and published by CRC Press. This book was released on 2020-04-15 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian Biostatistics conference was held, with the primary objective to stimulate the practical implementation of Bayesian statistics, and to promote the added-value for accelerating the discovery and the delivery of new cures to patients. This book is a synthesis of the conferences and debates, providing an overview of Bayesian methods applied to nearly all stages of research and development, from early discovery to portfolio management. It highlights the value associated with sharing a vision with the regulatory authorities, academia, and pharmaceutical industry, with a view to setting up a common strategy for the appropriate use of Bayesian statistics for the benefit of patients. The book covers: Theory, methods, applications, and computing Bayesian biostatistics for clinical innovative designs Adding value with Real World Evidence Opportunities for rare, orphan diseases, and pediatric development Applied Bayesian biostatistics in manufacturing Decision making and Portfolio management Regulatory perspective and public health policies Statisticians and data scientists involved in the research, development, and approval of new cures will be inspired by the possible applications of Bayesian methods covered in the book. The methods, applications, and computational guidance will enable the reader to apply Bayesian methods in their own pharmaceutical research.

Bayesian Modeling in Bioinformatics

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Publisher : CRC Press
ISBN 13 : 1420070185
Total Pages : 466 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Bayesian Modeling in Bioinformatics by : Dipak K. Dey

Download or read book Bayesian Modeling in Bioinformatics written by Dipak K. Dey and published by CRC Press. This book was released on 2010-09-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and c

Bayesian Methods in Health Economics

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Publisher : CRC Press
ISBN 13 : 1439895554
Total Pages : 246 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bayesian Methods in Health Economics by : Gianluca Baio

Download or read book Bayesian Methods in Health Economics written by Gianluca Baio and published by CRC Press. This book was released on 2012-11-12 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health economics is concerned with the study of the cost-effectiveness of health care interventions. This book provides an overview of Bayesian methods for the analysis of health economic data. After an introduction to the basic economic concepts and methods of evaluation, it presents Bayesian statistics using accessible mathematics. The next chapters describe the theory and practice of cost-effectiveness analysis from a statistical viewpoint, and Bayesian computation, notably MCMC. The final chapter presents three detailed case studies covering cost-effectiveness analyses using individual data from clinical trials, evidence synthesis and hierarchical models and Markov models. The text uses WinBUGS and JAGS with datasets and code available online.

Bayesian Approaches to Clinical Trials and Health-Care Evaluation

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Publisher : John Wiley & Sons
ISBN 13 : 9780471499756
Total Pages : 416 pages
Book Rating : 4.4/5 (997 download)

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Book Synopsis Bayesian Approaches to Clinical Trials and Health-Care Evaluation by : David J. Spiegelhalter

Download or read book Bayesian Approaches to Clinical Trials and Health-Care Evaluation written by David J. Spiegelhalter and published by John Wiley & Sons. This book was released on 2004-01-16 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries. Order a copy of this author’s comprehensive text TODAY! The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions. Bayesian methods have become increasingly popular in recent years, notably in medical research, and although there are a number of books on Bayesian analysis, few cover clinical trials and biostatistical applications in any detail. Bayesian Approaches to Clinical Trials and Health-Care Evaluation provides a valuable overview of this rapidly evolving field, including basic Bayesian ideas, prior distributions, clinical trials, observational studies, evidence synthesis and cost-effectiveness analysis. Covers a broad array of essential topics, building from the basics to more advanced techniques. Illustrated throughout by detailed case studies and worked examples Includes exercises in all chapters Accessible to anyone with a basic knowledge of statistics Authors are at the forefront of research into Bayesian methods in medical research Accompanied by a Web site featuring data sets and worked examples using Excel and WinBUGS - the most widely used Bayesian modelling package Bayesian Approaches to Clinical Trials and Health-Care Evaluation is suitable for students and researchers in medical statistics, statisticians in the pharmaceutical industry, and anyone involved in conducting clinical trials and assessment of health-care technology.

Generalized Linear Models

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Publisher : CRC Press
ISBN 13 : 9780824790349
Total Pages : 450 pages
Book Rating : 4.7/5 (93 download)

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Book Synopsis Generalized Linear Models by : Dipak K. Dey

Download or read book Generalized Linear Models written by Dipak K. Dey and published by CRC Press. This book was released on 2000-05-25 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes how to conceptualize, perform, and critique traditional generalized linear models (GLMs) from a Bayesian perspective and how to use modern computational methods to summarize inferences using simulation. Introducing dynamic modeling for GLMs and containing over 1000 references and equations, Generalized Linear Models considers parametric and semiparametric approaches to overdispersed GLMs, presents methods of analyzing correlated binary data using latent variables. It also proposes a semiparametric method to model link functions for binary response data, and identifies areas of important future research and new applications of GLMs.

Bayesian Nonparametrics

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Publisher : Cambridge University Press
ISBN 13 : 1139484605
Total Pages : 309 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Bayesian Nonparametrics by : Nils Lid Hjort

Download or read book Bayesian Nonparametrics written by Nils Lid Hjort and published by Cambridge University Press. This book was released on 2010-04-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian nonparametrics works - theoretically, computationally. The theory provides highly flexible models whose complexity grows appropriately with the amount of data. Computational issues, though challenging, are no longer intractable. All that is needed is an entry point: this intelligent book is the perfect guide to what can seem a forbidding landscape. Tutorial chapters by Ghosal, Lijoi and Prünster, Teh and Jordan, and Dunson advance from theory, to basic models and hierarchical modeling, to applications and implementation, particularly in computer science and biostatistics. These are complemented by companion chapters by the editors and Griffin and Quintana, providing additional models, examining computational issues, identifying future growth areas, and giving links to related topics. This coherent text gives ready access both to underlying principles and to state-of-the-art practice. Specific examples are drawn from information retrieval, NLP, machine vision, computational biology, biostatistics, and bioinformatics.

Bayesian Designs for Phase I-II Clinical Trials

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Publisher : CRC Press
ISBN 13 : 1498709567
Total Pages : 310 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Bayesian Designs for Phase I-II Clinical Trials by : Ying Yuan

Download or read book Bayesian Designs for Phase I-II Clinical Trials written by Ying Yuan and published by CRC Press. This book was released on 2017-12-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I–II Clinical Trials describes how phase I–II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes. Written by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity.