Basic Biology and Clinical Impact of Immunosenescence

Download Basic Biology and Clinical Impact of Immunosenescence PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 008054648X
Total Pages : 323 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!


Book Synopsis Basic Biology and Clinical Impact of Immunosenescence by : G. Pawelec

Download or read book Basic Biology and Clinical Impact of Immunosenescence written by G. Pawelec and published by Elsevier. This book was released on 2003-05-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ageing is of perennial interest as a universal feature in all human societies. The genetic background and biochemical bases of ageing processes are currently being revealed in unprecedented detail. It is emerging that one of the main hurdles to be overcome in achieving a long and healthy lifespan is the maintenance of a properly functioning immune system. The main cause of death in people who have achieved "successful ageing" (which mostly means not having succumbed to cancer or cardiovascular disease) is infectious disease, caused by immunosenescence. This book contains chapters by many of the leaders in the field of immune-related issues in ageing and remediation.

Handbook on Immunosenescence

Download Handbook on Immunosenescence PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402090633
Total Pages : 1693 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Handbook on Immunosenescence by : Tamas Fulop

Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Melatonin and Melatonergic Drugs in Clinical Practice

Download Melatonin and Melatonergic Drugs in Clinical Practice PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 8132208250
Total Pages : 405 pages
Book Rating : 4.1/5 (322 download)

DOWNLOAD NOW!


Book Synopsis Melatonin and Melatonergic Drugs in Clinical Practice by : V. Srinivasan

Download or read book Melatonin and Melatonergic Drugs in Clinical Practice written by V. Srinivasan and published by Springer Science & Business Media. This book was released on 2014-01-10 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinson’s disease, Alzheimer’s disease. Additionally, melatonin’s therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonin’s antioxidant role in Duchenne’s muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science.

Immunosenescence

Download Immunosenescence PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387768424
Total Pages : 210 pages
Book Rating : 4.3/5 (877 download)

DOWNLOAD NOW!


Book Synopsis Immunosenescence by : Graham Pawelec

Download or read book Immunosenescence written by Graham Pawelec and published by Springer Science & Business Media. This book was released on 2008-12-18 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human immunosenescence contributes to morbidity and mortality in later life. Understanding the reasons for age-associated alterations to protective immunity in the elderly would ultimately improve and extend healthspan. The majority of the papers collected in this remarkable and timely volume address the mechanisms responsible for immune ageing in humans. They also consider what might be accomplished to redress the erosion of immune competence with age.

Index Medicus

Download Index Medicus PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 2036 pages
Book Rating : 4.:/5 (319 download)

DOWNLOAD NOW!


Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Plant Bioactives as Natural Panacea against Age-Induced Diseases

Download Plant Bioactives as Natural Panacea against Age-Induced Diseases PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0323913296
Total Pages : 500 pages
Book Rating : 4.3/5 (239 download)

DOWNLOAD NOW!


Book Synopsis Plant Bioactives as Natural Panacea against Age-Induced Diseases by : Kanti Bhooshan Pandey

Download or read book Plant Bioactives as Natural Panacea against Age-Induced Diseases written by Kanti Bhooshan Pandey and published by Elsevier. This book was released on 2022-10-17 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Bioactives as Natural Panacea Against Age-induced Diseases: Nutraceuticals and Functional Lead Compounds for Drug Development presents comprehensive information on the complications of aging and the bioactive phytochemicals that in specific herbal formulations, including beverages, can mitigate them. The book extensively describes the current information on the role of plant bioactive components in delaying or preventing the aging process and associated complications, while also covering different strategies and scientific evidence of possible synergistic effects of these studies, enabling the formulation of more effective natural drugs to intervene in aging and associated events. Chapters cover the broad areas of plant bioactive compounds in promoting healthy aging and longevity, including balancing glucose homeostasis, in cognitive impairments, age-related diseases, food trends and the anti-aging diet in Asia and other regions, as well as the social and economic impact of dietary patterns in aging interventions. Written by a team of global experts. - Describes plant bioactives for specific age disorders - Focuses on the discovery of new herbal origin drugs and potential druggable targets for the treatment of chronic diseases of world importance - Includes cutting-edge research information on cell senescence during aging and assesses the plant bioactive compounds

Handbook of Stem Cells

Download Handbook of Stem Cells PDF Online Free

Author :
Publisher : Gulf Professional Publishing
ISBN 13 : 9780124366411
Total Pages : 896 pages
Book Rating : 4.3/5 (664 download)

DOWNLOAD NOW!


Book Synopsis Handbook of Stem Cells by : Robert Paul Lanza

Download or read book Handbook of Stem Cells written by Robert Paul Lanza and published by Gulf Professional Publishing. This book was released on 2004 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying CD-ROM (in v. 2) has image collections which can be saved in PowerPoint or HTML.

Stem Cell Therapy for Autoimmune Disease

Download Stem Cell Therapy for Autoimmune Disease PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1000724670
Total Pages : 1406 pages
Book Rating : 4.0/5 (7 download)

DOWNLOAD NOW!


Book Synopsis Stem Cell Therapy for Autoimmune Disease by : Richard K. Burt

Download or read book Stem Cell Therapy for Autoimmune Disease written by Richard K. Burt and published by CRC Press. This book was released on 2019-11-11 with total page 1406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.

The Immune Response to Infection

Download The Immune Response to Infection PDF Online Free

Author :
Publisher : American Society for Microbiology Press
ISBN 13 : 1555815146
Total Pages : 1662 pages
Book Rating : 4.5/5 (558 download)

DOWNLOAD NOW!


Book Synopsis The Immune Response to Infection by : Stefan H. E. Kaufmann

Download or read book The Immune Response to Infection written by Stefan H. E. Kaufmann and published by American Society for Microbiology Press. This book was released on 2010-11-30 with total page 1662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the mechanisms of both the innate and adaptive immune systems as they relate to infection and disease. • Explores the underlying mechanisms of immunity and the many sequelae of host-pathogen interactions, ranging from the sterile eradication of the invader, to controlled chronic infection, to pathologic corollaries of the host-pathogen crosstalk. • Discusses the pathogenesis of certain autoimmune disorders and cancers that are induced by infectious agents but then become independent of the infection process. • Serves as a resource for immunologists, molecular microbiologists, infectious disease clinicians, researchers, and students.

Infection Management for Geriatrics in Long-Term Care Facilities

Download Infection Management for Geriatrics in Long-Term Care Facilities PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1420021117
Total Pages : 536 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Infection Management for Geriatrics in Long-Term Care Facilities by : Thomas T. Yoshikawa

Download or read book Infection Management for Geriatrics in Long-Term Care Facilities written by Thomas T. Yoshikawa and published by CRC Press. This book was released on 2006-09-14 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering an authoritative overview of all infection management protocols currently utilized by infectious disease specialists, geriatricians, and infection control practitioners, this Second Edition examines current strategies to diagnose, treat, control, and prevent common infectious diseases in long-term care geriatric facilities. Covering a wide

Tumor-Induced Immune Suppression

Download Tumor-Induced Immune Suppression PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387691189
Total Pages : 304 pages
Book Rating : 4.3/5 (876 download)

DOWNLOAD NOW!


Book Synopsis Tumor-Induced Immune Suppression by : Dmitry I. Gabrilovich

Download or read book Tumor-Induced Immune Suppression written by Dmitry I. Gabrilovich and published by Springer Science & Business Media. This book was released on 2008-01-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in a more or less cohesive structure and how they can help to improve immune response to tumors.

Geriatric Oncology

Download Geriatric Oncology PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9783319574141
Total Pages : 1150 pages
Book Rating : 4.5/5 (741 download)

DOWNLOAD NOW!


Book Synopsis Geriatric Oncology by : Martine Extermann

Download or read book Geriatric Oncology written by Martine Extermann and published by Springer. This book was released on 2020-01-30 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended as a comprehensive resource for clinicians and researchers seeking in-depth information on geriatric oncology. The coverage encompasses epidemiology, the biology and (patho)physiology of aging and cancer, geriatric assessment and management, hematologic malignancies, solid tumors, issues in patient care, and research methods. Since cancer is a disease of aging and people are living longer, most cancer patients are now aged 70 and older. Yet the more we age, the more diverse we become in terms of our health, biologic fitness, and cancer behavior. Typically, however, general oncology clinical trials address only a selected healthier and younger population of patients. Geriatric oncology is the area of oncology that addresses these issues but while a wealth of knowledge has been accumulated, information is often difficult to retrieve or insufficiently detailed. The SpringerReference program, in which this book is published, offers an ideal format for overcoming these limitations since it combines thorough coverage with access to living editions constantly updated chapter by chapter via a dynamic peer-review process, ensuring that information remains current and pertinent.

Energy Metabolism and Lifespan Determination

Download Energy Metabolism and Lifespan Determination PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080494765
Total Pages : 227 pages
Book Rating : 4.0/5 (84 download)

DOWNLOAD NOW!


Book Synopsis Energy Metabolism and Lifespan Determination by : M.P. Mattson

Download or read book Energy Metabolism and Lifespan Determination written by M.P. Mattson and published by Elsevier. This book was released on 2003-12-01 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts in the fields of energy metabolism, aging and oxidative stress provide an integrated view of how mechanisms involved in regulating energy metabolism are linked to fundamental processes of aging including cellular stress resistance and free radical production. During evolution signal transduction pathways and organ systems have been optimised for the efficient seeking, ingestion, storing and using of energy. These signalling pathways play prominent roles in lifespan determination with insulin and related signalling pathways being prime examples. The authors consider how lifespan and healthspan can be extended through knowledge of energy metabolism with the experimental model of dietary restriction being one example. The information in this volume of ACAG will foster novel approaches and experiments for further understanding the roles of energy metabolism in aging and disease.

Recent Advances in Psychology and Aging

Download Recent Advances in Psychology and Aging PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080522785
Total Pages : 271 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!


Book Synopsis Recent Advances in Psychology and Aging by : P. Costa

Download or read book Recent Advances in Psychology and Aging written by P. Costa and published by Elsevier. This book was released on 2003-12-10 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Events in the Psychology of Aging documents the successful integration of aging into the mainstream of psychology. Leading psychologists present overviews of the key issues and research findings on mainstream topics. These include cognitive neuroscience, visual attention, learning, memory and cognition, as well as personality and happiness. The intersection of aging content with mainstream psychology is also prominent in the areas of emotions, personality, and social psychology as seen in the chapters on subjective well-being, emotional development, self-esteem and personality trajectories.The seven chapters of this book offer information on such topics as: the seven sins of memory, categorizing the common breakdowns of memory in everyday life and the special breakdown of sins that increase with aging; problems with attention and learning; and offers answers to questions such as do emotions get blunted with age; do older people focus more on positive feelings; and the age old question of whether older people are happier than younger people is given in the chapter on the evolving concept of subjective well-being and the multifaceted nature of happiness. Questions about what occurs to one's self-esteem and personality are also masterfully discussed and the answers may be surprising. The concluding seventh chapter provides a cultural lens on the biopsychosocial study of aging.

Sleep and Aging

Download Sleep and Aging PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 9780444518767
Total Pages : 212 pages
Book Rating : 4.5/5 (187 download)

DOWNLOAD NOW!


Book Synopsis Sleep and Aging by : Mark P. Mattson

Download or read book Sleep and Aging written by Mark P. Mattson and published by Elsevier. This book was released on 2005-06-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes the mechanisms involved in the maintenance of neuroendocrine-immune interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability. The capacity of some hormones or nutritional factors in restoring and remodelling the neuroendocrine-immune response during ageing is reported presenting possible new anti-ageing strategies in order to reach healthy ageing and longevity

Functional Foods, Ageing and Degenerative Disease

Download Functional Foods, Ageing and Degenerative Disease PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 1855739011
Total Pages : 792 pages
Book Rating : 4.8/5 (557 download)

DOWNLOAD NOW!


Book Synopsis Functional Foods, Ageing and Degenerative Disease by : C Remacle

Download or read book Functional Foods, Ageing and Degenerative Disease written by C Remacle and published by Elsevier. This book was released on 2004-06-09 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Degenerative diseases linked to ageing populations are a growing problem for the developed world. Edited by two authorities, this important collection reviews the role of functional foods in helping to prevent a number of such degenerative conditions, from osteoporosis and obesity to immune system disorders and cancer.The book begins with a number of introductory chapters which discuss the regulation of functional foods in the EU, the role of diet generally in preventing degenerative disease. Part one then examines bone and oral health with chapters on the use of diet to control osteoporosis, the use of functional ingredients to improve bone strength, and ways of maintaining dental health. Part two discusses how obesity can be controlled, whilst part three looks at gut health and maintaining the immune function using functional ingredients such as probiotics and prebiotics. The final part of the book reviews research on functional foods and cancer with chapters on synbiotics, anti-angiogenic functional foods, glucosinolates, dietary fibre and phytoestrogens.Functional foods, ageing and degenerative disease is a standard reference for all those concerned with the role of functional foods in the prevention and control of degenerative disease. - Explores diet strategies for preventing diseases including osteoporosis - Summarises key management techniques for obesity, irritable bowel syndrome and oral health - Presents the role of functional foods in promoting good health

Cells, Aging, and Human Disease

Download Cells, Aging, and Human Disease PDF Online Free

Author :
Publisher : Oxford University Press
ISBN 13 : 0190286261
Total Pages : 504 pages
Book Rating : 4.1/5 (92 download)

DOWNLOAD NOW!


Book Synopsis Cells, Aging, and Human Disease by : Michael B. Fossel M.D.

Download or read book Cells, Aging, and Human Disease written by Michael B. Fossel M.D. and published by Oxford University Press. This book was released on 2004-06-10 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.