Atlas of Cytoarchitectonics of the Adult Human Cerebral Cortex

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Author :
Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805582896
Total Pages : 0 pages
Book Rating : 4.5/5 (828 download)

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Book Synopsis Atlas of Cytoarchitectonics of the Adult Human Cerebral Cortex by : Constantin Freiherr von Economo

Download or read book Atlas of Cytoarchitectonics of the Adult Human Cerebral Cortex written by Constantin Freiherr von Economo and published by S. Karger AG (Switzerland). This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: First English edition of a rare gem in the neurological sciences A milestone in neuroscience research, this high-profile Atlas depicts the cellular structure of practically every area of the human cortex with direct applications to current research in brain function. The entirety of the 112 original microphotographic plates, brilliant achievements in scientific microphotography and representing the 107 cytoarchitectonic areas of the human cerebral cortex, are reproduced in full size - large enough to be used for teaching purposes. An extensive introduction places the cytoarchitectonic studies of von Economo and Koskinas in a historical as well as a modern perspective, summarizing the essence of their findings and providing Brodmann area correlations. Biographies of von Economo and Koskinas and complete listings of their hard-to-find works are included in the Appendix. Originally published in German in 1925, it was considered a 'royal gift to science'. Revising Brodmann's nomenclature of 1909, the Nobel prize nominee von Economo and his colleague Koskinas took cytoarchitectonics to a new zenith, filling in gaps left by Brodmann on normal cortical structure, and documenting detailed findings in the frontal, parietal, temporal and occipital lobes, the insula, hippocampus, and superior limbic region. Far from being of purely academic or historical interest, this essential guide for all research on the cerebral cortex is of fundamental value to investigators in the brain and behavioral sciences, including basic, cognitive and evolutionary neuroscience, neuroanatomy, neurophysiology, neuroimaging, neuropsychology and neurolinguistics, as well as to physicians in the clinical fields of neurology, neuropathology, neurosurgery and psychiatry.

Cellular Structure of the Human Cerebral Cortex

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 380559061X
Total Pages : 266 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Cellular Structure of the Human Cerebral Cortex by : Constantin von Economo

Download or read book Cellular Structure of the Human Cerebral Cortex written by Constantin von Economo and published by Karger Medical and Scientific Publishers. This book was released on 2009-01-01 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in German and French, the work is considered to be unsurpassed in both its scientific eloquence and accurate photographic documentation. Revising Brodmann's cortical parcellation system, von Economo took cytoarchitectonics to a new zenith.>The revised edition contains newly compiled tables with extensive quantitative data on the 107 cytoarchitectonic areas of Economo and Koskinas, plus all the 'transition' areas and full reproductions of the original microphotographs. It also contains the concluding chapter that appeared only in the 1929 English edition, with Economo's later views on cytoarchitectonic neuropathology and evolutionary neuroscience, enriched with material and figures from his later studies. Last but not least a newly discovered manuscript by Georg N. Koskinas, appears in English for the first time. In it, Economo's collaborator presents an insightful analysis of the 'General Part' of their larger textbook of cytoarchitectonics.

Brodmann's

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387269193
Total Pages : 307 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Brodmann's by : K. Brodmann

Download or read book Brodmann's written by K. Brodmann and published by Springer Science & Business Media. This book was released on 2007-02-16 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third edition of the translation, by Laurence Garey, of "Vergleichende Lokalisationslehre der Grosshirnrinde" by Korbinian Brodmann, originally published by Barth-Verlag in Leipzig in 1909. It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology. In spite of this, few people have ever seen a copy of the 1909 monograph, and even fewer have actually read it! There had never been a complete English translation available until the first edition of the present translation of 1994, and the original book had been almost unavailable for 50 years or more, the few antiquarian copies still around commanding high prices. As Laurence Garey, too, used Brodmann’s findings and maps in his neurobiological work, and had the good fortune to have access to a copy of the book, he decided to read the complete text and soon discovered that this was much more than just a report of laboratory findings of a turn-of-the-twentieth-century neurologist. It was an account of neurobiological thinking at that time, covering aspects of comparative neuroanatomy, neurophysiology and neuropathology, as well as giving a fascinating insight into the complex relationships between European neurologists during the momentous times when the neuron theory was still new.

Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain

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Author :
Publisher : Academic Press
ISBN 13 : 0128011599
Total Pages : 204 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain by : Michael Petrides

Download or read book Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain written by Michael Petrides and published by Academic Press. This book was released on 2018-12-13 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain provides a comprehensive identification of the sulci and gyri of the human brain on a series of coronal sections of the average MNI brain and identifies the likely location of the cytoarchitectonic areas of the cerebral cortex. Presentation in MNI Stereotaxic Space enables the atlas to serve as a useful working tool for structural/functional neuroimagers attempting to identify the sulcus or gyrus and the likely cytoarchitectonic area within which a functional activation or a structural change has occurred. A brief introductory section discusses the history and current state of studies of the sulcal and gyral morphology and cytoarchitecture of the human cerebral cortex. Identifies all sulci and gyri of both hemispheres of the average MNI brain (rather than those of a single brain with its individual peculiarities) so that the average surface morphology of the human cerebral cortex is clearly revealed Presents the likely location of architectonic areas on the average MNI brain so that researchers can report their findings in a manner that is readily translatable from laboratory to laboratory Offers succinct commentary on the relation of sulci and gyri to architectonic areas, which will be useful to those looking to identify the cortical area within which functional or structural changes occurred Offers succinct commentaries on the diversity of names often used to refer to the exact same area that will be useful to those struggling to navigate the often confusing cerebral cortex nomenclature

Cytoarchitectonic atlas of the human cerebral cortex. In Russian

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Book Synopsis Cytoarchitectonic atlas of the human cerebral cortex. In Russian by : S. A. Sarkisova

Download or read book Cytoarchitectonic atlas of the human cerebral cortex. In Russian written by S. A. Sarkisova and published by . This book was released on 1955 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cellular Structure of the Human Cerebral Cortex

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Author :
Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805590624
Total Pages : 0 pages
Book Rating : 4.5/5 (96 download)

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Book Synopsis Cellular Structure of the Human Cerebral Cortex by : Constantin Freiherr von Economo

Download or read book Cellular Structure of the Human Cerebral Cortex written by Constantin Freiherr von Economo and published by S. Karger AG (Switzerland). This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in German and French, the work is considered to be unsurpassed in both its scientific eloquence and accurate photographic documentation. Revising Brodmann's cortical parcellation system, von Economo took cytoarchitectonics to a new zenith. The revised edition contains newly compiled tables with extensive quantitative data on the 107 cytoarchitectonic areas of Economo and Koskinas, plus all the 'transition' areas and full reproductions of the original microphotographs. It also contains the concluding chapter that appeared only in the 1929 English edition, with Economo's later views on cytoarchitectonic neuropathology and evolutionary neuroscience, enriched with material and figures from his later studies. Last but not least a newly discovered manuscript by Georg N. Koskinas, appears in English for the first time. In it, Economo's collaborator presents an insightful analysis of the 'General Part' of their larger textbook of cytoarchitectonics.

Atlas of the Human Brain

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Author :
Publisher : Academic Press
ISBN 13 : 0128028017
Total Pages : 458 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Atlas of the Human Brain by : Juergen K Mai

Download or read book Atlas of the Human Brain written by Juergen K Mai and published by Academic Press. This book was released on 2015-12-02 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of Atlas of the Human Brain presents the anatomy of the brain at macroscopic and microscopic levels, featuring different aspects of brain morphology and topography. This greatly enlarged new edition provides the most detailed and accurate delineations of brain structure available. It includes features which assist in the new fields of neuroscience – functional imaging, resting state imaging and tractography. Atlas of the Human Brain is an essential guide to those working with human brain imaging or attempting to relate their observations on experimental animals to humans. Totally new in this edition is the inclusion of Nissl plates with delineation of cortical areas (Brodmann’s areas), the first time that these areas have been presented in serial histological sections. Winner of the 2016 British Medical Association Award for Best Illustrated Text and previous edition winner of the Award of Excellence from the American Association of Publishers The contents of the Atlas of the brain in MNI stereotaxic space has been extensively expanded from 143 pages, showing 69 levels through the hemisphere, to 314 pages representing 99 levels In addition to the fiber-stained (myelin) plates, we now provide fifty new (Nissl) plates covering cytoarchitecture. These are interdigitated within the existing myelin plates of the stereotaxic atlas All photographic plates now represent the complete hemisphere All photographs of the cell- and fiber-stained sections have been transformed to fit the MNI-space Major fiber tracts are identified in the fiber-stained sections In the Nissl plates cortical delineations (Brodmann’s areas) are provided for the first time The number of diagrams increased to 99. They were now generated from the 3D reconstruction of the hemisphere registered to the MNI- stereotaxic space. They can be used for immediate comparison between our atlas and experimental and clinical imaging results Parts of cortical areas are displayed at high magnification on the facing page of full page Nissl sections. Images selected highlight those areas which are thought to correspond with those published by von Economo and Koskinas (1925) A novel way of depicting cortical areal pattern is used: The cortical cytoarchitectonic ribbon is unfolded and presented linearly. This linear representation of the cortex enables the comparison of different interpretations of cortecal areas and allows mapping of activation sites Low magnification diagrams in the horizontal (axial) and sagittal planes are included, calculated from the 3D model of the atlas brain

Brodmann's

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Author :
Publisher : Springer
ISBN 13 : 9780387269177
Total Pages : 298 pages
Book Rating : 4.2/5 (691 download)

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Book Synopsis Brodmann's by : K. Brodmann

Download or read book Brodmann's written by K. Brodmann and published by Springer. This book was released on 2005-11-15 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third edition of the translation, by Laurence Garey, of "Vergleichende Lokalisationslehre der Grosshirnrinde" by Korbinian Brodmann, originally published by Barth-Verlag in Leipzig in 1909. It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology. In spite of this, few people have ever seen a copy of the 1909 monograph, and even fewer have actually read it! There had never been a complete English translation available until the first edition of the present translation of 1994, and the original book had been almost unavailable for 50 years or more, the few antiquarian copies still around commanding high prices. As Laurence Garey, too, used Brodmann’s findings and maps in his neurobiological work, and had the good fortune to have access to a copy of the book, he decided to read the complete text and soon discovered that this was much more than just a report of laboratory findings of a turn-of-the-twentieth-century neurologist. It was an account of neurobiological thinking at that time, covering aspects of comparative neuroanatomy, neurophysiology and neuropathology, as well as giving a fascinating insight into the complex relationships between European neurologists during the momentous times when the neuron theory was still new.

Cortical Areas

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Author :
Publisher : CRC Press
ISBN 13 : 1134473516
Total Pages : 807 pages
Book Rating : 4.1/5 (344 download)

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Book Synopsis Cortical Areas by : Almut Schuez

Download or read book Cortical Areas written by Almut Schuez and published by CRC Press. This book was released on 2002-05-30 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of areas in the cerebral cortex has a long history, bringing empirical data into close relation with fundamental conceptual issues about the cortex. The subject is currently being revitalized with the advent of new experimental methods and this book brings a modern perspective to the study of these areas. Cortical Areas: Unity and Diversi

The Cytoarchitectonics of the Human Cerebral Cortex

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Author :
Publisher :
ISBN 13 :
Total Pages : 186 pages
Book Rating : 4.:/5 (95 download)

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Book Synopsis The Cytoarchitectonics of the Human Cerebral Cortex by : Constantin Freiherr von Economo

Download or read book The Cytoarchitectonics of the Human Cerebral Cortex written by Constantin Freiherr von Economo and published by . This book was released on 1929 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Brodmann's

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Author :
Publisher : Springer
ISBN 13 : 9781441938954
Total Pages : 0 pages
Book Rating : 4.9/5 (389 download)

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Book Synopsis Brodmann's by : K. Brodmann

Download or read book Brodmann's written by K. Brodmann and published by Springer. This book was released on 2010-10-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third edition of the translation, by Laurence Garey, of "Vergleichende Lokalisationslehre der Grosshirnrinde" by Korbinian Brodmann, originally published by Barth-Verlag in Leipzig in 1909. It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology. In spite of this, few people have ever seen a copy of the 1909 monograph, and even fewer have actually read it! There had never been a complete English translation available until the first edition of the present translation of 1994, and the original book had been almost unavailable for 50 years or more, the few antiquarian copies still around commanding high prices. As Laurence Garey, too, used Brodmann’s findings and maps in his neurobiological work, and had the good fortune to have access to a copy of the book, he decided to read the complete text and soon discovered that this was much more than just a report of laboratory findings of a turn-of-the-twentieth-century neurologist. It was an account of neurobiological thinking at that time, covering aspects of comparative neuroanatomy, neurophysiology and neuropathology, as well as giving a fascinating insight into the complex relationships between European neurologists during the momentous times when the neuron theory was still new.

Brain Mapping: The Methods

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Author :
Publisher : Academic Press
ISBN 13 : 9780126930191
Total Pages : 912 pages
Book Rating : 4.9/5 (31 download)

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Book Synopsis Brain Mapping: The Methods by : Arthur W. Toga

Download or read book Brain Mapping: The Methods written by Arthur W. Toga and published by Academic Press. This book was released on 2002-09-25 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of scientists and laboratories involved with brain mapping is increasing exponentially; and the second edition of this comprehensive reference has also grown much larger than the first (published in 1996), including, for example, five chapters on structural and functional MRI where the fi

Microstructural Parcellation of the Human Cerebral Cortex

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Publisher : Springer Science & Business Media
ISBN 13 : 3642378242
Total Pages : 260 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Microstructural Parcellation of the Human Cerebral Cortex by : Stefan Geyer

Download or read book Microstructural Parcellation of the Human Cerebral Cortex written by Stefan Geyer and published by Springer Science & Business Media. This book was released on 2013-07-04 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.

Atlas of Brain Function

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Author :
Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Atlas of Brain Function by : William W. Orrison

Download or read book Atlas of Brain Function written by William W. Orrison and published by . This book was released on 1995 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Atlas of Human Brain Connections

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0199541167
Total Pages : 533 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Atlas of Human Brain Connections by : Marco Catani

Download or read book Atlas of Human Brain Connections written by Marco Catani and published by Oxford University Press, USA. This book was released on 2012-06-14 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.

Broca's Region

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Publisher : Oxford University Press
ISBN 13 : 0195177649
Total Pages : 436 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Broca's Region by : Yosef Grodzinsky

Download or read book Broca's Region written by Yosef Grodzinsky and published by Oxford University Press. This book was released on 2006-04-20 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Broca's region has been in the news ever since scientists realized that particular cognitive functions could be localized to parts of the cerebral cortex. Its discoverer, Paul Broca, was one of the first researchers to argue for a direct connection between a concrete behavior--in this case, the use of language--and a specific cortical region. Today, Broca's region is perhaps the most famous part of the human brain, and for over a century, has persisted as the focus of intense research and numerous debates. The name has even penetrated mainstream culture through popular science and the theater. Broca's region is famous for a good reason: As language is one of the most distinctive human traits, the cognitive mechanisms that support it and the tissues in which these mechanisms are housed are also quite complex, and so have the potential to reveal a lot not only about how words, phrases, sentences, and grammatical rules are instantiated in neural tissue, but also, and more broadly, about how brain function relates to behavior. Paul Broca's discoveries were an important, driving force behind the more general effort to relate complex behavior to particular parts of the cerebral cortex, which, significantly, produced the first brain maps.These early studies also, however, suffered from the use of crude techniques, definitions, and distinctions, as well as from ill founded and misdirected assumptions. Although much has been discovered since Broca's work, even today, these problems have not been completely solved. Nonetheless, particularly as a result of important advances made in neuroimaging during the past two decades, Broca's region and all language areas are currently being investigated from every angle. Indeed, as the volume of research into the relations between brain and language has created several communities, each with its own concepts, methods, and considerations, it seemed that it was time to stop, get together, and reflect on the state of the art.This book is the result of that collective reflection, which took place primarily at the Broca's Region Workshop, held in Julich and Aachen, Germany, in June 2004. In it, Yosef Grodzinsky and Katrin Amunts tried to accomplish a nearly impossible task: to mix intellectual traditions and cultures, and juxtapose rather disparate bodies of knowledge, styles of reasoning, and forms of argumentation. Participants were scientists with diverse backgrounds; each invited to contribute his/her particular take, with the hope that a coherent, perhaps even novel, picture would emerge. All of the participants have a special interest in Broca's Region, and represent the myriad angles from which we currently approach it: neuroanatomy, physiology, evolutionary biology, cognitive psychology, clinical neurology, functional imaging, speech and language research, computational biology, and psycho-, neuro-, and theoretical linguistics. The book's main chapters are the contributions of the Workshop's participants and their research teams. Parts of the discussion during the Workshop are included to underscore the richness of viewpoints, and to give readers an idea of the level of interaction that took place. As Broca's region is such a historically significant concept and rich area, this book contains a collection of classic and recent-yet-classic papers. Along with cutting-edge science, Grodzinsky and Amunts want to remind readers of the celebrated past from which much can be learned. The historical chapters include the first two papers written by Paul Broca, as well some work by two of the most important neurologists of the nineteenth century, Ludwig Lichtheim and John Hughlings-Jackson. Also included are parts of twentieth century papers by Korbinian Brodmann, Roman Jakobson, Norman Geschwind, Harold Goodglass, and Jay Mohr. Because this book both reflects the state of the art in Broca's-region research and contains a tribute to its celebrated past, it will be a valuable resource for student and professional researchers. It will also stimulate further interdisciplinary research, which is a significant contribution, as the project called "Broca's region," encompassing the study of brain/language relations, is far from finished.

Descartes' Error

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Author :
Publisher : Penguin
ISBN 13 : 014303622X
Total Pages : 338 pages
Book Rating : 4.1/5 (43 download)

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Book Synopsis Descartes' Error by : Antonio Damasio

Download or read book Descartes' Error written by Antonio Damasio and published by Penguin. This book was released on 2005-09-27 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since Descartes famously proclaimed, "I think, therefore I am," science has often overlooked emotions as the source of a person’s true being. Even modern neuroscience has tended, until recently, to concentrate on the cognitive aspects of brain function, disregarding emotions. This attitude began to change with the publication of Descartes’ Error in 1995. Antonio Damasio—"one of the world’s leading neurologists" (The New York Times)—challenged traditional ideas about the connection between emotions and rationality. In this wondrously engaging book, Damasio takes the reader on a journey of scientific discovery through a series of case studies, demonstrating what many of us have long suspected: emotions are not a luxury, they are essential to rational thinking and to normal social behavior.