Assessment Of The Clinical Utility Of Pharmacogenomic Testing On Drug Utilization In A High Risk Patient Population

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Assessment of the Clinical Utility of Pharmacogenomic Testing on Drug Utilization in a High-risk Patient Population

Author : Sarah Marie Villarreal
Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.:/5 (961 download)

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Book Synopsis Assessment of the Clinical Utility of Pharmacogenomic Testing on Drug Utilization in a High-risk Patient Population by : Sarah Marie Villarreal

Download or read book Assessment of the Clinical Utility of Pharmacogenomic Testing on Drug Utilization in a High-risk Patient Population written by Sarah Marie Villarreal and published by . This book was released on 2016 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potential benefits of incorporating pharmacogenomic (PGx) testing into clinical practice include minimizing adverse drug reactions (ADRs) and improving clinical outcomes based on genetic differences of individuals. Despite significant advances in bridging PGx from bench-to-bedside, there have been slower efforts to incorporate PGx testing into routine clinical practice due to the lack of robust evidence for clinical utility and convincing studies demonstrating improved health outcomes. The UPGRADE Registry, an interim, prospective, observational trial aimed at assessing several key aspects of PGx testing: 1) determining the total number of high-risk patients that had at least one drug change and its impact on patients; 2) describing the genetic polymorphisms representing populations in the US and Puerto Rico; 3) to evaluate the association between race/ethnicity and the percentage of drug changes; and 4) identifying individual factors (age, gender, co-morbidities, number of drugs, and race/ethnicity) affecting the number of drug changes implemented by practitioners. Approximately 25% of the entire cohort underwent drug changes after PGx testing results (defined as dose modifications, drug substitutions, and drug discontinuations); however, almost 50% of patients with adverse drug reactions (ADRs) with drug-drug or drug-gene interactions experienced subsequent therapeutic modifications. The ADR cohort reported herein also experienced significant decreases in the number of ADRs after PGx testing recommendations. The major subset of the UPGRADE population (95%) was characterized as experiencing a lack of drug activity (LOA); only 25% of these patients experienced any therapeutic drug modification. The UPGRADE registry confirms currently published literature that provides additional support to the distribution of polymorphic changes in drug metabolizing enzymes within the US population. There were no differences in the percentage of drug changes that occurred when comparing differing ethnicities, indicating a lack of healthcare disparity within this high-risk population. Several factors were identified as independent predictors of the number of drug changes. A positive relationship, (i.e. increasing the likelihood of drug change) was seen with number of drugs, gastrointestinal disorders, and hepatobiliary diseases. This prospective, observational, study demonstrated the potential of drug modifications in prevention of subsequent ADRs and improving LOA based on PGx testing of drug metabolizing enzymes. Additional education to clinical providers regarding the use and benefit of PGx testing is warranted based on guidance provided by our PGx testing results and a lack of subsequent drug changes.

Pharmacogenomics

Author : Yui-Wing Francis Lam
Publisher : Academic Press
ISBN 13 : 0123983037
Total Pages : 515 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Pharmacogenomics by : Yui-Wing Francis Lam

Download or read book Pharmacogenomics written by Yui-Wing Francis Lam and published by Academic Press. This book was released on 2013-02-12 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference. - Multi-contributed book and chapters are written by contributors who are experts in their field - Provides perspectives from those involved in all aspects of pharmacogenomics—including academic, regulatory, economic, industry and medical—to illustrate how all of the pieces fit together and where the challenges may be - Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications - Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research

Cardiovascular Genetics and Genomics

Author : Dhavendra Kumar
Publisher : Springer
ISBN 13 : 3319661140
Total Pages : 921 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Cardiovascular Genetics and Genomics by : Dhavendra Kumar

Download or read book Cardiovascular Genetics and Genomics written by Dhavendra Kumar and published by Springer. This book was released on 2018-01-17 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions. Cardiovascular Genetics and Genomics: Principles and Clinical Practice includes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.

Pharmacogenomics in Psychiatry

Author : M. Schwab
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805594992
Total Pages : 148 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Pharmacogenomics in Psychiatry by : M. Schwab

Download or read book Pharmacogenomics in Psychiatry written by M. Schwab and published by Karger Medical and Scientific Publishers. This book was released on 2010-06-25 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there have been major developments in the fields of pharmacogenetics and pharmacogenomics, with the potential to make drug treatments in psychiatric medicine more effective. However, improvements in drug efficacy and tolerability, as well as finding the optimal dosage, can only be realized if in vivo mechanisms of drug action and ADME (absorption, distribution, metabolism, excretion) processes (pharmacokinetics) of psychopharmacological agents are better understood. In this volume, current progress and perspectives in pharmacogenetic testing of drug-metabolizing enzymes, drug transporters and other drug targets involved in the response to psychotropic agents are described extensively. This provides a timely overview of what has been achieved in the area of psychiatric pharmacogenomics alongside some promising directions and perspectives for future research.Psychiatrists, general medical doctors as well as pharmacologists and clinical pharmacologists will find new insights into the development and applications of pharmacogenomics in psychiatry.

Textbook of Personalized Medicine

Author : Kewal K. Jain
Publisher : Humana Press
ISBN 13 : 1493925539
Total Pages : 762 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain

Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Humana Press. This book was released on 2015-03-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.

The Evidence-Based Guide to Antidepressant Medications

Author : Anthony J. Rothschild
Publisher : American Psychiatric Pub
ISBN 13 : 1585629804
Total Pages : 426 pages
Book Rating : 4.5/5 (856 download)

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Book Synopsis The Evidence-Based Guide to Antidepressant Medications by : Anthony J. Rothschild

Download or read book The Evidence-Based Guide to Antidepressant Medications written by Anthony J. Rothschild and published by American Psychiatric Pub. This book was released on 2012-09-24 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second book in the Evidence-Based Guides series, The Evidence-Based Guide to Antidepressant Medications, provides a clear reference to the current knowledge and evidence base for the use of antidepressants among a variety of patients across a wide range of disorders. Chapters within this guide are authored by experts in their respective areas of practice, and synthesize a large amount of medical literature into a comprehensive, yet understandable, concise, reader-friendly guide. Each chapter covers both the FDA-approved and off-label use of antidepressant medications and the evidence base for their use. Each chapter also features useful tables pertaining to specific topics, such as summaries of uses and efficacy, and important clinical pearls of wisdom in the Key Clinical Concepts. Topics covered in chapters within this text include: Use of selective serotonin reuptake inhibitors, MAOIs, and tricyclic antidepressants in major depressive disorder, bipolar depression, psychotic depression, and treatment-resistant depression. Acute management of anxiety disorders, obsessive-compulsive disorder, and specific phobias through antidepressant use. Use of antidepressant medication in medically ill patients, such as those with cardiovascular, pulmonary, gastrointestinal, renal, and endocrine diseases, as well as cancer, chronic pain, HIV, burns and hospital-based trauma. Developmental considerations necessary to keep in mind when prescribing antidepressants to children and adolescents, along with an outline of controlled studies and their special attention to safety. Medication management in geriatric patients, including antidepressant use among depressed elderly patients with dementia, stroke, or Parkinson's disease. Risks and benefits of prescribing antidepressants during pregnancy and lactation. Together, the authors have synthesized a large amount of medical literature into a comprehensive, yet understandable, concise, reader-friendly guide. The Evidence-Based Guide to Antidepressant Medications is a must-have reference for psychiatrists and other practicing clinicians, residents in training, psychiatric nurses, social workers and researchers.

Evolution of Translational Omics

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Psychiatric Pharmacogenomics

Author : David Mrazek
Publisher : Oxford University Press
ISBN 13 : 0195367294
Total Pages : 276 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Psychiatric Pharmacogenomics by : David Mrazek

Download or read book Psychiatric Pharmacogenomics written by David Mrazek and published by Oxford University Press. This book was released on 2010-06-10 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric Pharmacogenomics is a book written to help clinicians to use pharmacogenomic testing to improve the pharmacotherapy that they provide for their patients. It is designed to teach clinicians how to order pharmacogenomic tests and interpret the results. Clinical examples are used to underscore the specific indications for pharmacogenomic testing and to clarify the clinical usefulness of identifying atypical genotypes that result in problematic responses to medication. The first section of the book begins with a basic review of molecular genetics. Additionally, the book also includes an extensive glossary of technical terms associated with molecular genetics and pharmacogenomics. The clinical utility of pharmacogenomic testing is demonstrated throughout the book by describing the implications of genetic variations for the care of individual patients. The second section of the book is organized into fourteen chapters that each focus on the clinical implications of testing for specific genes for which variants have been associated with either therapeutic response or side effects of psychotropic medications. Each of these chapters is structured in the same manner and involves a description of the gene and its significant variants. Each chapter also includes one or more clinical vignettes. The third section of the book discusses the clinical usefulness of pharmacogenomic testing, ethical issues associated with pharmacogenomic testing, and provides predictions for the future development of more sophisticated pharmacogenomic testing.

Genomic and Precision Medicine

Author : Geoffrey S. Ginsburg
Publisher : Academic Press
ISBN 13 : 0128006536
Total Pages : 379 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genomic and Precision Medicine by : Geoffrey S. Ginsburg

Download or read book Genomic and Precision Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2022-04-09 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. - Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers - Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice - Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice - Covers case studies that highlight the practical use of genomics in the management of patients

The Evidence-Based Guide to Antipsychotic Medications

Author : Anthony J. Rothschild
Publisher : American Psychiatric Pub
ISBN 13 : 1585629294
Total Pages : 395 pages
Book Rating : 4.5/5 (856 download)

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Book Synopsis The Evidence-Based Guide to Antipsychotic Medications by : Anthony J. Rothschild

Download or read book The Evidence-Based Guide to Antipsychotic Medications written by Anthony J. Rothschild and published by American Psychiatric Pub. This book was released on 2010-01-12 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Evidence-Based Guide to Antipsychotic Medications is designed to provide both clinicians and residents with focused, comprehensive, and clinically relevant information regarding the use of antipsychotic medications to treat a broad range of psychiatric conditions -- from mood and anxiety disorders to substance abuse, personality disorders, and schizophrenia. The volume editor is a renowned psychiatrist and author with more than 25 years of experience in both clinical and research settings diagnosing and treating patients with mood and psychotic disorders. In addition, each of the volume's 13 contributors is an expert with many years of clinical experience to draw on.The book is down-to-earth and reader-friendly and is structured for maximal utility in both coverage and format: Key Clinical Points cap each chapter, synthesizing and summarizing the knowledge you can take away, and serving both as a refresher for those using the book as a reference and as a study aid to master the material. Both FDA-approved and off-label use of antipsychotic medications are addressed, reflecting the reality of clinical practice on the front lines. Use of antipsychotic medications in both the pediatric and geriatric populations, a potentially controversial subject, is addressed in a nonsensational, straight-forward manner. The Appendixes provide a wealth of information in tabular format, including drug tables (names, strengths, formulations, pharmacokinetics, and dosing); advice on initiating and monitoring antipsychotic medications; common side effects and their management; and special considerations for use during pregnancy and breastfeeding. The Evidence-Based Guide to Antipsychotic Medications is the first in a new series that strives to take evidence-based psychiatry from gold standard to standard practice. Scientifically up-to-date and rigorous, yet accessible and easy to understand, this volume stands alone as an indispensable resource on the topic.

Improving Outcomes with Clinical Decision Support

Author : Jerome A. Osheroff, MD, FACP, FACMI
Publisher : HIMSS
ISBN 13 : 1938904206
Total Pages : 350 pages
Book Rating : 4.9/5 (389 download)

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Book Synopsis Improving Outcomes with Clinical Decision Support by : Jerome A. Osheroff, MD, FACP, FACMI

Download or read book Improving Outcomes with Clinical Decision Support written by Jerome A. Osheroff, MD, FACP, FACMI and published by HIMSS. This book was released on 2012 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacogenomics

Author : Howard L. McLeod
Publisher :
ISBN 13 : 9781932658699
Total Pages : 485 pages
Book Rating : 4.6/5 (586 download)

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Book Synopsis Pharmacogenomics by : Howard L. McLeod

Download or read book Pharmacogenomics written by Howard L. McLeod and published by . This book was released on 2009-01-01 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics offers the opportunity for clinicians to dramatically improve the health outcomes of millions of patients receiving drug therapy. However, this opportunity is tempered by the challenge of learning the seemingly limitless amount of genetic information assembled during the past decade, with new knowledge developing rapidly. ACCP has developed this textbook to assist clinicians in meeting this challenge. The enhanced second edition, written by leaders in pharmacogenomics from different practice areas, disciplines, and research environments, combines the basics of pharmacogenomics with disease-specific applications to give students and practitioners a solid foundation for understanding the basic science of pharmacogenomics and the skills for integrating pharmacogenomics into daily clinical practice.

The American Psychiatric Association Publishing Textbook of Psychopharmacology

Author : Alan F. Schatzberg
Publisher : American Psychiatric Pub
ISBN 13 : 1615371222
Total Pages : 1850 pages
Book Rating : 4.6/5 (153 download)

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Book Synopsis The American Psychiatric Association Publishing Textbook of Psychopharmacology by : Alan F. Schatzberg

Download or read book The American Psychiatric Association Publishing Textbook of Psychopharmacology written by Alan F. Schatzberg and published by American Psychiatric Pub. This book was released on 2017-05-10 with total page 1850 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Psychiatric Association Publishing Textbook of Psychopharmacology is an indispensable and comprehensive resource for clinicians and trainees who prescribe psychotropic medications. Updated to reflect the new DSM-5 classification, this revised Fifth Edition maintains the user-friendly structure of its predecessors while offering in-depth coverage of the latest research in pharmacological principles, classes of drugs, and psychiatric disorders. Introductory chapters provide a theoretical grounding in clinical applications, with topics ranging from neurotransmitters to brain imaging in psychopharmacology. The bulk of the book is devoted to various classes of drugs, including antidepressants, anxiolytics, antipsychotics, mood stabilizers, and other agents, with each class divided into chapters on specific drugs -- either new or revised to include the latest findings and trends. Finally, the section on psychopharmacological treatment addresses evidence-based principles of clinical care for the full spectrum of mental disorders and conditions -- from depression to chronic pain -- as well as for specific populations and circumstances -- from children and adolescents to psychiatric emergencies -- offering information on topics such as medication selection, combination and maintenance dosing regimens, monitoring and management of side effects, and strategies for optimizing treatment response. The book's beneficial features are many: The section on principles of pharmacology has been revised and reorganized to incorporate recent discoveries from the fields of neurobiology, genetics, brain imaging, and epidemiology. History and discovery, structure--activity relationships, pharmacological profiles, pharmacokinetics and disposition, mechanisms of action, indications and efficacy, side effects and toxicology, and drug--drug interactions are addressed for each agent. This consistent structure places the desired information at the clinician's fingertips and facilitates study for trainees. Coverage of drugs approved since the last edition is thorough, encompassing new antidepressants (e.g., vortioxetine), new antipsychotics (e.g., cariprazine), and agents on the clinical horizon (e.g., ketamine). More than 180 tables and graphs present critically important data in an accessible way. A work of uncommon scientific rigor and clinical utility, The American Psychiatric Association Publishing Textbook of Psychopharmacology provides state-of-the-art information on both the principles and the practice of psychopharmacological treatment of psychiatric disorders.

Pharmacogenomics in Drug Discovery and Development

Author : Qing Yan
Publisher : Springer Nature
ISBN 13 : 107162573X
Total Pages : 618 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Pharmacogenomics in Drug Discovery and Development by : Qing Yan

Download or read book Pharmacogenomics in Drug Discovery and Development written by Qing Yan and published by Springer Nature. This book was released on 2022-09-06 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.

Personalized Cancer Chemotherapy

Author : Da Yong Lu
Publisher : Woodhead Publishing
ISBN 13 : 0081003471
Total Pages : 85 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Personalized Cancer Chemotherapy by : Da Yong Lu

Download or read book Personalized Cancer Chemotherapy written by Da Yong Lu and published by Woodhead Publishing. This book was released on 2014-12-05 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Cancer Chemotherapy separately describes and addresses "individualized cancer chemotherapy" (ICC) strategies new and old, to provide readers with new insights into their characteristics and techniques, as well as key debates and future trends in this area. The book devotes chapters to drug sensitivity testing, cancer biomarkers and bioinformatics detection, pharmacogenetics, individualized antimetastatic therapy, drug combinations, assistant chemotherapy, and cost-effectiveness considerations. A major obstacle to controlling cancer growth and metastases in patients is the inappropriate use of anticancer and antimetastatic drugs. Researchers and clinicians are now beginning to focus on ICC also called "personalized cancer chemotherapy" (PCC), to improve therapeutic quality and outcomes by selecting and prescribing the most appropriate and effective drugs. Using genetic, molecular, and bioinformatics data and modern experimental techniques, known tumor genes can be detected more easily than ever before; the average speed of genetic sequencing has increased 15,000 to 50,000 times since the Human Geonme Project was completed. This book will help readers understand the pros and cons of each individualized cancer chemotherapy strategy from different angles so as to make good judgments and predictions of drug responses and clinical outcomes. - Explores the central components of cancer treatment - Investigates new developments in cancer treatment - Discusses the many strategies of individualized cancer chemotherapy

Handbook of Clinical Rating Scales and Assessment in Psychiatry and Mental Health

Author : Lee Baer
Publisher : Springer Science & Business Media
ISBN 13 : 1597453870
Total Pages : 334 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Handbook of Clinical Rating Scales and Assessment in Psychiatry and Mental Health by : Lee Baer

Download or read book Handbook of Clinical Rating Scales and Assessment in Psychiatry and Mental Health written by Lee Baer and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric clinicians should use rating scales and questionnaires often, for they not only facilitate targeted diagnoses and treatment; they also facilitate links to empirical literature and systematize the entire process of management. Clinically oriented and highly practical, the Handbook of Clinical Rating Scales and Assessment in Psychiatry and Mental Health is an ideal tool for the busy psychiatrist, clinical psychologist, family physician, or social worker. In this ground-breaking text, leading researchers provide reviews of the most commonly used outcome and screening measures for the major psychiatric diagnoses and treatment scenarios. The full range of psychiatric disorders are covered in brief but thorough chapters, each of which provides a concise review of measurement issues related to the relevant condition, along with recommendations on which dimensions to measure – and when. The Handbook also includes ready-to-photocopy versions of the most popular, valid, and reliable scales and checklists, along with scoring keys and links to websites containing on-line versions. Moreover, the Handbook describes well known, structured, diagnostic interviews and the specialized training requirements for each. It also includes details of popular psychological tests (such as neuropsychological, personality, and projective tests), along with practical guidelines on when to request psychological testing, how to discuss the case with the assessment consultant and how to integrate information from the final testing report into treatment. Focused and immensely useful, the Handbook of Clinical Rating Scales and Assessment in Psychiatry and Mental Health is an invaluable resource for all clinicians who care for patients with psychiatric disorders.

Registries for Evaluating Patient Outcomes

Author : Agency for Healthcare Research and Quality/AHRQ
Publisher : Government Printing Office
ISBN 13 : 1587634333
Total Pages : 385 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ

Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.