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Author : Rosa Chiara Paolicelli
Publisher : Frontiers Media SA
ISBN 13 : 2889742911
Total Pages : 220 pages
Book Rating : 4.8/5 (897 download)
Download or read book Assessing Microglial Function and Identity written by Rosa Chiara Paolicelli and published by Frontiers Media SA. This book was released on 2022-02-04 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0123973481
Total Pages : 993 pages
Book Rating : 4.1/5 (239 download)
Download or read book Patterning and Cell Type Specification in the Developing CNS and PNS written by and published by Academic Press. This book was released on 2013-05-06 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
Author : Marie-Ève Tremblay
Publisher : Springer Nature
ISBN 13 : 3031555295
Total Pages : 635 pages
Book Rating : 4.0/5 (315 download)
Download or read book Microglia written by Marie-Ève Tremblay and published by Springer Nature. This book was released on with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mario F. Wulliman
Publisher : Birkhäuser
ISBN 13 : 3034889798
Total Pages : 142 pages
Book Rating : 4.0/5 (348 download)
Download or read book Neuroanatomy of the Zebrafish Brain written by Mario F. Wulliman and published by Birkhäuser. This book was released on 2012-12-06 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jane Williams
Publisher : John Wiley & Sons
ISBN 13 : 1118699629
Total Pages : 367 pages
Book Rating : 4.1/5 (186 download)
Download or read book Acute Stroke Nursing written by Jane Williams and published by John Wiley & Sons. This book was released on 2013-05-07 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a medical emergency that requires immediate medical attention. With active and efficient nursing management in the initial hours after stroke onset and throughout subsequent care, effective recovery and rehabilitation is increased. Acute Stroke Nursing provides an evidence-based, practical text facilitating the provision of optimal stroke care during the primary prevention, acute and continuing care phases. This timely and comprehensive text is structured to follow the acute stroke pathway experienced by patients. It explores the causes, symptoms and effects of stroke, and provides guidance on issues such as nutrition, continence, positioning, mobility and carer support. The text also considers rehabilitation, discharge planning, palliative care and the role of the nurse within the multi-professional team. Acute Stroke Nursing is the definitive reference on acute stroke for all nurses and healthcare professionals wishing to extend their knowledge of stroke nursing. Evidence-based and practical in style, with case studies and practice examples throughout Edited and authored by recognised stroke nursing experts, clinicians and leaders in the field of nursing practice, research and education The first text to explore stroke management from UK and international perspectives, and with a nursing focus
Author : William M. Reichert
Publisher : CRC Press
ISBN 13 : 1420009303
Total Pages : 300 pages
Book Rating : 4.4/5 (2 download)
Download or read book Indwelling Neural Implants written by William M. Reichert and published by CRC Press. This book was released on 2007-12-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel
Author : Amanda Sierra
Publisher : Frontiers E-books
ISBN 13 : 2889193691
Total Pages : 173 pages
Book Rating : 4.8/5 (891 download)
Download or read book Never-resting microglia: physiological roles in the healthy brain and pathological implications written by Amanda Sierra and published by Frontiers E-books. This book was released on 2015-02-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microglia are largely known as the major orchestrators of the brain inflammatory response. As such, they have been traditionally studied in various contexts of disease, where their activation has been assumed to induce a wide range of detrimental effects. In the last few years, a series of discoveries have challenged the current view of microglia, showing their active and positive contribution to normal brain function. This Research Topic reviewed the novel physiological roles of microglia in the developing, mature and aging brain, under non-pathological conditions. In particular, this Research Topic discussed the cellular and molecular mechanisms by which microglia contribute to the formation, pruning and plasticity of synapses; the regulation of adult neurogenesis as well as hippocampal learning and memory; among other important roles. Because these novel findings defy our understanding of microglial function in health as much as in disease, this Research Topic also summarized the current view of microglial nomenclature, phenotypes, origin and differentiation, and contribution to various brain pathologies. Additionally, novel imaging approaches and molecular tools to study microglia in their non-activated state have been discussed. In conclusion, this Research Topic seeked to emphasize how the current research in neuroscience is challenged by never-resting microglia.
Author : Patrizia Giannoni
Publisher : Frontiers Media SA
ISBN 13 : 2889639096
Total Pages : 288 pages
Book Rating : 4.8/5 (896 download)
Download or read book Identification of Multiple Targets in the Fight against Alzheimer’s Disease written by Patrizia Giannoni and published by Frontiers Media SA. This book was released on 2020-07-31 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Subashika Govindan
Publisher : Frontiers Media SA
ISBN 13 : 2832544401
Total Pages : 153 pages
Book Rating : 4.8/5 (325 download)
Download or read book Advances and Challenges in Studying Brain Disorders: from Development to Aging written by Subashika Govindan and published by Frontiers Media SA. This book was released on 2024-02-07 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chengjin Gao
Publisher : Frontiers Media SA
ISBN 13 : 2832546528
Total Pages : 355 pages
Book Rating : 4.8/5 (325 download)
Download or read book Characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases written by Chengjin Gao and published by Frontiers Media SA. This book was released on 2024-03-19 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The systemic inflammatory response is evident in inflammatory diseases, and the immune system secretes many cytokines involved, resulting in a robust immune response. For example, the pathogenesis of sepsis includes abnormal immune cell activation in the early stages as well as sepsis-related immunosuppression. During the immunosuppressive phase, CD4+ T cells, CD8+ T cells, Th17 cells, and γδ T cells are reduced while regulatory T cells increase. At the same time, T lymphocytes and neutrophils, as immune effector cells, interact with each other and play a key role in regulating the immune response to immune-inflammatory diseases. The increased release of neutrophil extracellular trap networks (NETs) by neutrophils leads to a significant upregulation of NETs-DNA-MPO, which further aggravates the septic inflammatory response and organ functional impairment. Therefore, it is important to deeply investigate the characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases, and targeting therapies against them may provide new ideas for the precise treatment of diseases.
Author : Charles Watson
Publisher : Academic Press
ISBN 13 : 0123694973
Total Pages : 815 pages
Book Rating : 4.1/5 (236 download)
Download or read book The Mouse Nervous System written by Charles Watson and published by Academic Press. This book was released on 2011-11-28 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness
Author : Yu Tang
Publisher : Frontiers Media SA
ISBN 13 : 2889455254
Total Pages : 327 pages
Book Rating : 4.8/5 (894 download)
Download or read book Microglial Polarization in the Pathogenesis and Therapeutics of Neurodegenerative Diseases written by Yu Tang and published by Frontiers Media SA. This book was released on 2018 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microglia-mediated neuroinflammation is one of the shared prominent hallmarks among various forms of neurodegeneration. Depending on the milieu in which microglia become activated, the polarization of microglia shows to be heterogeneous with diverse functional phenotypes that range from pro-inflammatory phenotypes to immunosuppressive phenotypes. Therefore, targeting microglial polarization holds great promise for the treatment of neurodegeneration. This eBook focuses on the potential mechanisms of microglial polarization that are critically associated with a broad spectrum of neurodegenerative diseases, including Parkinson’s disease (PD), Alzheimer’s disease (AD), Amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), Traumatic brain injury (TBI), glaucomatous neurodegeneration and prion diseases. This topic also involves the therapeutic targeting of microglial polarization by nutritional and pharmacological modulators. Moreover, this topic describes advanced technologies employed for studying microglia. Age-related changes in microglia functions are also discussed. Overall, this eBook provides comprehensive understandings of microglial polarization in the course of neurodegeneration, linking with aging-related microglial alterations and technologies developed for microglial studies. Hopefully, it will also give comprehensive insights into various aspects of therapeutic treatment for neurodegeneration, through targeting microglial polarization.
Author : Alvin Volkman
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.3/5 (91 download)
Download or read book Mononuclear Phagocyte Biology written by Alvin Volkman and published by Marcel Dekker. This book was released on 1984 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author : James Winkler
Publisher : Birkhäuser
ISBN 13 : 3034887418
Total Pages : 268 pages
Book Rating : 4.0/5 (348 download)
Download or read book Apoptosis and Inflammation written by James Winkler and published by Birkhäuser. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apoptosis is a form of cell death that occurs in a controlled manner and is generally noninflammatory in nature. Apoptosis, or programmed cell death, implies a cell death that is part of a normal physiological process of pruning of unneeded cells. However, many disease conditions utilize apoptosis for pathological ends, resulting in inappropriate cell death and tissue destruction. This book starts with an introduction that reviews the general characteristics of apoptosis, its regulation and its role in physiology and disease. Next, the book focuses on three areas as they relate to inflammatory cells and diseases. The first area consists of chapters on signals for apoptosis important to inflammatory cells, namely growth factors and arachidonic acid metabolism. The next area that the book focuses on are effects at the cellular level, on cell survival versus cell death and signals critical for cell function in both normal and disease states. These topics are covered in chapters on lymphocytes, granulocytes, chondrocytes and keratinocytes. The last area that the book focuses on are events at the level of tissue and disease, looking at the evidence for altered apoptosis and/or apoptotic processes in immune and inflammatory diseases. These topics are covered in chapters on rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal disease. Together, these chapters will provide the reader with the latest insight in the role of apoptosis in inflammatory cells and diseases. This book starts with an introduction that reviews the general characteristics of apoptosis, its regulation and its role in physiology and disease. Next, the book focuses on three areas as they relate to inflammatory cells and diseases. The first area consists of chapters on signals for apoptosis important to inflammatory cells, namely growth factors and arachidonic acid metabolism. The next area that the book focuses on are effects at the cellular level, on cell survival versus cell death and signals critical for cell function in both normal and disease states. These topics are covered in chapters on lymphocytes, granulocytes, chondrocytes and keratinocytes. The last area that the book focuses on are events at the level of tissue and disease, looking at the evidence for altered apoptosis and/or apoptotic processes in immune and inflammatory diseases. These topics are covered in chapters on rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal disease. Together, these chapters will provide the reader with the latest insight in the role of apoptosis in inflammatory cells and diseases.
Author : Graeme Milligan
Publisher : Springer
ISBN 13 : 3319506935
Total Pages : 258 pages
Book Rating : 4.3/5 (195 download)
Download or read book Free Fatty Acid Receptors written by Graeme Milligan and published by Springer. This book was released on 2017-02-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Author : Gunawan Indrayanto
Publisher : Frontiers Media SA
ISBN 13 : 2832509088
Total Pages : 175 pages
Book Rating : 4.8/5 (325 download)
Download or read book Development, assessment, improvement, and standardization of methods in herbal drug research written by Gunawan Indrayanto and published by Frontiers Media SA. This book was released on 2022-12-08 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
