Approaches for Integrating Information from Radiation Biology and Epidemiology to Enhance Low-dose Health Risk Assessment

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Publisher :
ISBN 13 : 9781944888244
Total Pages : pages
Book Rating : 4.8/5 (882 download)

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Book Synopsis Approaches for Integrating Information from Radiation Biology and Epidemiology to Enhance Low-dose Health Risk Assessment by :

Download or read book Approaches for Integrating Information from Radiation Biology and Epidemiology to Enhance Low-dose Health Risk Assessment written by and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This Report extends the concepts and approaches discussed in NCRP Report No. 171 and Commentary No. 24 to further reduce uncertainty in radiation risk assessments at low doses and low dose rates, thereby enhancing the bases for radiation protection guidance"--

Approaches for Integrating Information from Radiation Biology and Epidemology to Enhance Low-Dose Health Risk Assessments

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ISBN 13 : 9781523132263
Total Pages : 0 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Approaches for Integrating Information from Radiation Biology and Epidemology to Enhance Low-Dose Health Risk Assessments by : National Council on Radiation Protection and Measurements

Download or read book Approaches for Integrating Information from Radiation Biology and Epidemology to Enhance Low-Dose Health Risk Assessments written by National Council on Radiation Protection and Measurements and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Future of Low Dose Radiation Research in the United States

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Publisher : National Academies Press
ISBN 13 : 030949771X
Total Pages : 143 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Future of Low Dose Radiation Research in the United States by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Future of Low Dose Radiation Research in the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-13 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposures at low doses of radiation, generally taken to mean doses below 100 millisieverts, are of primary interest for setting standards for protecting individuals against the adverse effects of ionizing radiation. However, there are considerable uncertainties associated with current best estimates of risks and gaps in knowledge on critical scientific issues that relate to low dose radiation. The Nuclear and Radiation Studies Board of the National Academies hosted the symposium on The Future of Low Dose Radiation Research in the United States on May 8 and 9, 2019. The goal of the symposium was to provide an open forum for a national discussion on the need for a long-term strategy to guide a low dose radiation research program in the United States. The symposium featured presentations on low dose radiation programs around the world, panel discussions with representatives from governmental and nongovernmental organizations about the need for a low dose radiation research program, reviews of low dose radiation research in epidemiology and radiation biology including new directions, and lessons to be learned from setting up large research programs in non-radiation research fields. This publication summarizes the presentation and discussion of the symposium.

Health Risks from Exposure to Low Levels of Ionizing Radiation

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Publisher : National Academies Press
ISBN 13 : 0309133343
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Health Risks from Exposure to Low Levels of Ionizing Radiation by : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation

Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Health Effects of Low Doses of Radiation

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Publisher :
ISBN 13 : 9780983545071
Total Pages : pages
Book Rating : 4.5/5 (45 download)

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Book Synopsis Health Effects of Low Doses of Radiation by :

Download or read book Health Effects of Low Doses of Radiation written by and published by . This book was released on 2015-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Kalabishis, Gina

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (733 download)

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Book Synopsis Kalabishis, Gina by :

Download or read book Kalabishis, Gina written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Low-level Radiation

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Publisher :
ISBN 13 :
Total Pages : 744 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Low-level Radiation by : United States. Department of Energy. Technical Information Center

Download or read book Low-level Radiation written by United States. Department of Energy. Technical Information Center and published by . This book was released on 1978 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Analysis of Cancer Risks in Populations Near Nuclear Facilities

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Publisher : National Academies Press
ISBN 13 : 0309255716
Total Pages : 424 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Analysis of Cancer Risks in Populations Near Nuclear Facilities by : National Research Council

Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Effects of Low Dose and Low Dose Rate Radiation

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Publisher : Academic Press
ISBN 13 : 1483281833
Total Pages : 349 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Effects of Low Dose and Low Dose Rate Radiation by : Oddvar F. Nygaard

Download or read book Effects of Low Dose and Low Dose Rate Radiation written by Oddvar F. Nygaard and published by Academic Press. This book was released on 2013-10-22 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 6: Effects of Low Dose and Low Dose Rate Radiation examines the biological effects of low dose and low dose rate ionizing radiation on a broad scale, covering various articles from microdosimetry to analyses of human responses. Estimates of the effects on humans from low doses or from sustained exposures to low dose rates of ionizing radiations are of critical importance for the assessment of radiation risks under occupational and environmental conditions. This book consists of such knowledge that is essential for radiation protection and governmental regulatory activities pertaining to radiation exposure. This volume is intended for radiobiologists, radiation epidemiologists, radiation physicists, radiation safety personnel, health officials, and individuals involved in regulatory activities.

Science and Decisions

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Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science and Decisions by : National Research Council

Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Low Dose Radiation

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Publisher : Taylor & Francis Group
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Low Dose Radiation by : K. F. Baverstock

Download or read book Low Dose Radiation written by K. F. Baverstock and published by Taylor & Francis Group. This book was released on 1989 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviewing the current status of studies on human populations exposed to radiation, including the survivors of the atomic bombings in Japan, this book goes on to look at the risks to man from exposure to low doses of radiation, which must be inferred from populations exposed to high doses.

Health Effects of Exposure to Low Levels of Ionizing Radiations

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Publisher : National Academies Press
ISBN 13 : 0309580528
Total Pages : 87 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Health Effects of Exposure to Low Levels of Ionizing Radiations by : Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations (Beir VII)

Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiations written by Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations (Beir VII) and published by National Academies Press. This book was released on 1998-08-18 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: The US Environmental Protection Agency Office of Radiation and Indoor Air asked the National Research Council to evaluate whether sufficient new data exist to warrant a reassessment of health risks reported in Health Effects of Exposure to Low Levels of Ionizing Radiations (BEIR V) in 1990. To respond to this request, the National Research Council assembled the Committee on Health Risks of Exposure to Low Levels of Ionizing Radiations. The work of the committee was conducted in what was called the BEIR VII phase-1 study. To assist the committee during its deliberations, various scientists were consulted for advice, and a workshop on the impact of biology on risk assessment was held in collaboration with the Department of Energy Office of Health and Environmental Research. The intent of the workshop was to address the implications of new understanding of the biologic basis of radiation injury and carcinogenesis for risk assessment.

Radiation Dose Reconstruction for Epidemiologic Uses

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Publisher : National Academies Press
ISBN 13 : 0309176832
Total Pages : 150 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiation Dose Reconstruction for Epidemiologic Uses by : National Research Council

Download or read book Radiation Dose Reconstruction for Epidemiologic Uses written by National Research Council and published by National Academies Press. This book was released on 1995-05-16 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing public concern about releases of radiation into the environment has focused attention on the measurement of exposure of people living near nuclear weapons production facilities or in areas affected by accidental releases of radiation. Radiation-Dose Reconstruction for Epidemiologic Uses responds to the need for criteria for dose reconstruction studies, particularly if the doses are to be useful in epidemiology. This book provides specific and practical recommendations for whether, when, and how studies should be conducted, with an emphasis on public participation. Based on the expertise of scientists involved in dozens of dose reconstruction projects, this volume: Provides an overview of the basic requirements and technical aspects of dose reconstruction. Presents lessons to be learned from dose reconstructions after Chernobyl, Three Mile Island, and elsewhere. Explores the potential benefits and limitations of biological markers. Discusses how to establish the "source term"â€"that is, to determine what was released. Explores methods for identifying the environmental pathways by which radiation reaches the body. Offers details on three major categories of dose assessment.

The Million Person Study of Low-Dose Radiation Health Effects

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Author :
Publisher : Routledge
ISBN 13 : 9781032607177
Total Pages : 0 pages
Book Rating : 4.6/5 (71 download)

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Book Synopsis The Million Person Study of Low-Dose Radiation Health Effects by : Andre Bouville

Download or read book The Million Person Study of Low-Dose Radiation Health Effects written by Andre Bouville and published by Routledge. This book was released on 2024-11-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original research findings of The Million Person Study of Low-Dose Radiation Health Effects (MPS), the largest and most comprehensive epidemiologic study of its kind to investigate the health effects of low-level chronic radiation exposure on American workers and veterans throughout the 20th century. Since the early 1900s, epidemiologists have studied the consequences of radiation exposures, yet the health effects of low levels received gradually over time remain unresolved. This uncertainty comes at a time when the public and workers are experiencing ever-increasing levels of radiation exposure from advances in medical radiation imaging techniques (e.g., CT scans), frequent flying at high altitudes, and environmental and occupational exposures. The MPS is providing answers by studying 30 radiation-exposed U.S. populations, including workers at nuclear power plants, radiologists, workers at former Manhattan Project sites, nuclear submariners, nuclear weapons test participants (atomic veterans), industrial radiographers, and radium dial painters. Ongoing for more than 20 years and coordinated by the National Council on Radiation Protection and Measurements, Vanderbilt University Medical Center and Memorial Sloan Kettering Cancer Center, the MPS is a national effort supported by the Department of Energy, National Aeronautics and Space Administration, U.S. Navy, Defense Threat Reduction Agency, Nuclear Regulatory Commission, Centers for Disease Control and Prevention, and the Environmental Protection Agency. Unparalleled in scope and quality, the MPS provides an understanding of low-dose health effects that is desperately needed for decision makers and the radiation protection community as society continues to increase the uses of radiation technologies. Individual chapters were originally published in the International Journal of Radiation Biology.

Leveraging Advances in Modern Science to Revitalize Low-Dose Radiation Research in the United States

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Publisher : National Academies Press
ISBN 13 : 9780309275774
Total Pages : pages
Book Rating : 4.2/5 (757 download)

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Book Synopsis Leveraging Advances in Modern Science to Revitalize Low-Dose Radiation Research in the United States by : National Academies Of Sciences Engineeri

Download or read book Leveraging Advances in Modern Science to Revitalize Low-Dose Radiation Research in the United States written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2023-03-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation exposure at low doses (below 100 milligray) or low-dose rates (less than 5 milligray per hour) occurs in a wide range of medical, industrial, military, and commercial settings. The effects of exposure at these levels are not fully understood, but there are long-standing concerns that such exposure could negatively affect human health. Although cancer has been linked to low-dose radiation exposure for decades, there is increasing evidence that low-dose radiation exposure may also be associated with cardiovascular disease, neurological disorders, immune dysfunction, and cataracts. Recent advances in research, new tools, and a coordinated multidisciplinary research program could help fill knowledge gaps about the health impacts of low-dose radiation exposures. This report calls for the development of a U.S. research program to study how low doses of radiation affect cancer, cardiovascular disease, neurological disorders, and other disease risks. Research should also better define the impacts of radiation doses, dose rates, types of radiation, and exposure duration. The report estimates $100 million annually for the next 15 years would be required to conduct epidemiological and biological research, and to establish an infrastructure for research.

Deriving Organ Doses and Their Uncertainty for Epidemiologic Studies (with a Focus on the One Million U.S. Workers and Veterans Study of Low-dose Radiation Health Effects).

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Publisher :
ISBN 13 : 9781944888060
Total Pages : pages
Book Rating : 4.8/5 (88 download)

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Book Synopsis Deriving Organ Doses and Their Uncertainty for Epidemiologic Studies (with a Focus on the One Million U.S. Workers and Veterans Study of Low-dose Radiation Health Effects). by :

Download or read book Deriving Organ Doses and Their Uncertainty for Epidemiologic Studies (with a Focus on the One Million U.S. Workers and Veterans Study of Low-dose Radiation Health Effects). written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Uncertainties in the Estimation of Radiation Risks and Probability of Disease Causation

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Publisher : National Council on Radiation
ISBN 13 : 9780983545019
Total Pages : 418 pages
Book Rating : 4.5/5 (45 download)

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Book Synopsis Uncertainties in the Estimation of Radiation Risks and Probability of Disease Causation by : National Council on Radiation Protection and Measurements

Download or read book Uncertainties in the Estimation of Radiation Risks and Probability of Disease Causation written by National Council on Radiation Protection and Measurements and published by National Council on Radiation. This book was released on 2012 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forlagets beskrivelse: NCRP Report No. 171, Uncertainties in the Estimation of Radiation Risks and Probability of Disease Causation, considers the types and magnitude of the several uncertainties that are a component of the risk assessment process for cancer, heritable and noncancer effects following radiation exposure. These uncertainties can result from the nature of the input data as well as from the specific analysis and models used for developing the risk estimates. Topics addressed in this Report include: (a) uncertainties associated with extrapolation of dose-response relationships observed in primary epidemiological studies to estimate the risk per unit dose (i.e., organ dose or whole-body dose) in the U.S. population and other exposed populations; (b) applications of meta-analyses or pooled analyses to increase the statistical power in evaluating uncertainties in dose-response relationships for exposed human populations; (c) uncertainties associated with extrapolation of dose-response relationships observed for populations exposed to acute doses of high-energy gamma rays to estimate the risk per unit dose in populations exposed to fractionated or low-dose rate chronic exposures; (d) uncertainties associated with extrapolation of the dose-response relationships observed for populations exposed to high-energy gamma rays to estimate the risk per unit dose in populations exposed to low-energy photons, low-energy electrons, alpha particles, and neutrons with various energies; (e) comparison of uncertainties associated with risk estimated for individual tissue or organ sites with the uncertainties associated with estimating risk of all tumors combined due to whole-body exposure; (f) evaluation of opportunities for using additional epidemiological and laboratory-based biological information to modify estimates of uncertainty in risk estimation for cancer, noncancer effects, and severe heritable disorders; (f) procedures for accounting for dose uncertainty in epidemiological dose-response analyses; and (g) evaluation of the combined effect of uncertainty in dose estimation with the uncertainty in estimation of risk per unit dose in estimating the overall risk. This Report also provides a comprehensive analysis of uncertainties on the estimation of probability of radiation-induced disease, including: (1) application of organ doses and associated uncertainties in estimation of probability of disease causation; (2) evaluation of inherent uncertainties in calculating the probability of disease causation (in an individual), or assigned share of excess relative risk for various types of cancer attributable to radiation exposure; and (3) methods of improving existing procedures for estimating disease probability based on input organ doses and their uncertainties. The issue of uncertainty in estimation of radiation-induced risks of cancer, noncancer diseases, and heritable genetic effects analyzed in this Report is of great importance in evaluating the effects of ionizing radiation on human health, in decisions involving the safe use of ionizing radiation and in addressing public controversy. Uncertainty analyses should become increasingly important in the future as the sophisticated methodologies continue to develop and become more available.