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Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders
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Book Synopsis Applications of Stem Cells and Derived Exosomes in Neurodegenerative Disorders by : Sadaf Jahan
Download or read book Applications of Stem Cells and Derived Exosomes in Neurodegenerative Disorders written by Sadaf Jahan and published by Springer Nature. This book was released on with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of Stem Cell Applications by : Khawaja H. Haider
Download or read book Handbook of Stem Cell Applications written by Khawaja H. Haider and published by Springer Nature. This book was released on with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang
Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
Book Synopsis Neural Stem Cells In Health And Disease by : Ashok K Shetty
Download or read book Neural Stem Cells In Health And Disease written by Ashok K Shetty and published by World Scientific Publishing Company. This book was released on 2015-08-28 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide on neural stem cell behavior in health and disease. The book confers the altered behavior of endogenous neural stem cells in neurodegenerative disease conditions and the prospects of neural stem cell therapy for alleviating brain dysfunction in a variety of neurodegenerative disorders.Neural stem cell activity and neurogenesis in the adult brain is now confirmed in virtually all mammalian species including humans. Hence, a series of chapters in the first half of the book discusses the current knowledge on mechanisms of neural stem cell activity, the extent and functional significance of neurogenesis in the adult brain under normal, aged and disease environments, the susceptibility of neural stem cells and the plasticity of neurogenesis to alcohol, drugs of abuse and anesthetic agents, and advanced techniques that trigger neurogenesis in non-neurogenic regions.A second series of chapters in this book are focused on discussing the promise and efficacy of grafting of neural stem cells and/or other stem cells for treating neurological disorders such as Parkinson's disease, stroke, temporal lobe epilepsy, Alzheimer's disease and spinal cord injury. The final chapter confers on advances that are made in manufacturing a variety of neural cell types from human pluripotent stem cells that can be used as donor cells for cell transplantation.
Book Synopsis Stem Cell-based Therapy for Neurodegenerative Diseases by : Fabin Han
Download or read book Stem Cell-based Therapy for Neurodegenerative Diseases written by Fabin Han and published by Springer Nature. This book was released on 2020-10-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.
Book Synopsis Stem Cells and Neurodegenerative Diseases by : Laurent Lescaudron
Download or read book Stem Cells and Neurodegenerative Diseases written by Laurent Lescaudron and published by CRC Press. This book was released on 2014-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential of stem cells for ameliorating the quality of life of patients with neurological and neurodegenerative diseases. It discusses results of pre-clinical investigations and case studies on the effects of stem cell transplantation on cell death, as well as to promote/stimulate neuroprotection after brain and spinal cord injury through trophic support, cell replacement and remyelination. The book covers the maintenance of the balance between stem cells and their progenitors within their niche, both under normal and degenerative processes and with ischemic stroke, multiple sclerosis, and brain tumor.
Book Synopsis Role of Exosomes in Biological Communication Systems by : Faisal A. Alzahrani
Download or read book Role of Exosomes in Biological Communication Systems written by Faisal A. Alzahrani and published by Springer Nature. This book was released on 2020-11-20 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.
Book Synopsis Developing stem cell-based therapies for neural repair by : Clare Parish
Download or read book Developing stem cell-based therapies for neural repair written by Clare Parish and published by Frontiers Media SA. This book was released on 2015-01-28 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression and has resulted in significant hope for the successes of stem cell research. The properties of stem cells render them appropriate for cell replacement therapy, endogenous repair, disease modeling as well as high-throughput drug screening and development. Such applications will aide in increasing our knowledge and developing treatments for neurodegenerative disorders such as Parkinson’s disease and Huntington’s diseases as well as neural traumas including ischemic brain damage and traumatic brain injury. This Frontiers Research topic encouraged contributions from the general field of stem cell biology, with a particular emphasis on utilizing these cells to develop new therapies for neural repair. Related articles deal with issues such as: breakthroughs in stem cell proliferation/differentiation methodologies, using pluripotent and neural stem cells for transplantation and endogenous repair, the use of patient derived stem cells for disease modeling, using stem cells for drug discovery as well as the ethical issues related to the use of stem cells.
Book Synopsis Exosomes, Stem Cells and MicroRNA by : Karl L. Mettinger
Download or read book Exosomes, Stem Cells and MicroRNA written by Karl L. Mettinger and published by Springer. This book was released on 2018-05-12 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.
Book Synopsis Stem Cells in Neurodegeneration: Disease Modeling and Therapeutics by : Kim A. Staats
Download or read book Stem Cells in Neurodegeneration: Disease Modeling and Therapeutics written by Kim A. Staats and published by Frontiers Media SA. This book was released on 2021-08-17 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Exosomes Based Drug Delivery Strategies for Brain Disorders by : Neeraj Mishra
Download or read book Exosomes Based Drug Delivery Strategies for Brain Disorders written by Neeraj Mishra and published by Springer Nature. This book was released on with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stem Cells and Aging by : Cesar V. Borlongan
Download or read book Stem Cells and Aging written by Cesar V. Borlongan and published by Frontiers Media SA. This book was released on 2021-07-14 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Borlongan and Dr. Steinberg serve as consultants to stem cell-based companies, hold patents and patent applications, and have funded grants related to stem cell biologics and applications.
Book Synopsis Induced Pluripotent Stem Cells in Brain Diseases by : Vivi M. Heine
Download or read book Induced Pluripotent Stem Cells in Brain Diseases written by Vivi M. Heine and published by Springer Science & Business Media. This book was released on 2011-11-23 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic “memories” of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson’s disease and Vanishing White Matter (VWM).
Book Synopsis Stem Cells by : Mariusz Z. Ratajczak
Download or read book Stem Cells written by Mariusz Z. Ratajczak and published by Springer Nature. This book was released on 2020-01-02 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.
Download or read book GeNeDis 2018 written by Panayiotis Vlamos and published by Springer Nature. This book was released on 2020-05-28 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.
Book Synopsis Current Challenges in Cell Therapy for Neurodegenerative Diseases by :
Download or read book Current Challenges in Cell Therapy for Neurodegenerative Diseases written by and published by Academic Press. This book was released on 2022-11-22 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Transplantation and Gene Therapy in Neurodegenerative Disease, Volume 166 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors who cover Challenges in translating a cell therapy to GMP, The challenges in developing a cell therapy for Huntington’s disease, Challenges of cell therapies for retinal diseases, Challenges of gene therapy in Huntington’s Disease, Technological advances and barriers to gene therapy, Considerations in the development of cell therapy modulation for spinal cord injury treatment, Challenges of developing glial cell therapy for ALS, and more. Other chapters in this comprehensive release include Exploring cell and gene therapy in current animal models of Parkinson’s and Huntington’s disease, Considerations for the use of biomaterials to support cell therapy in degenerative disease, Neurosurgical challenges/innovations in cell and gene therapy delivery, Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders, Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, and More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review on Neurobiology serials Updated release includes the latest information on Cell Transplantation and Gene Therapy in Neurodegenerative Disease
Book Synopsis Neurological Regeneration by : Phuc Van Pham
Download or read book Neurological Regeneration written by Phuc Van Pham and published by Springer. This book was released on 2017-01-16 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource explores the regenerative potential of stem cells in the nervous system, with a focus on clinical applications. The expertly authored chapters discuss cell-based therapies for spinal cord injury and regeneration, traumatic brain injury, glioblastoma, Parkinson's Disease, ischemic stroke, cell banking, human embryonic stem cells and related concerns, harvesting of adipose tissue, and more. These topics are contextualized within a discussion of future directions of these therapies. Neurological Regeneration, part of Springer’s Stem Cells in Clinical Applications series, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, neurology, regenerative medicine or tissue engineering.
