Application Of Optical Coherence Tomography In Investigating Cell Migration

Download Application Of Optical Coherence Tomography In Investigating Cell Migration full books in PDF, epub, and Kindle. Read online Application Of Optical Coherence Tomography In Investigating Cell Migration ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Application of Optical Coherence Tomography in Investigating Cell Migration

Author : Sara Rey
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (835 download)

DOWNLOAD NOW!

Book Synopsis Application of Optical Coherence Tomography in Investigating Cell Migration by : Sara Rey

Download or read book Application of Optical Coherence Tomography in Investigating Cell Migration written by Sara Rey and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemotaxis and cell migration are important processes for life, involved in organism development and homeostasis and implicated in a number of disease states. Dictyostelium discoideum, an amoeba, is a useful model for investigation of chemotaxis and development, due to its ability to undergo chemotactic aggregation and development upon starvation. Although cell migration has been well described on planar transparent surfaces, it is uncertain how well these conditions replicate the natural environment of a cell. However, attempts to better replicate these environments generally make use of opaque substrates and 3D matrices, in which it is more challenging to image cell migration. Protocols were developed to enable optical coherence tomography, a 3D structural imaging technique which requires no sample processing or staining, to be successfully employed in imaging Dictyostelium cell migration in time-lapse on non-transparent substrata and within an agarose gel. I compared the effects of two substrates, a nitrocellulose filter and a polystyrene Petri dish on aggregating cells and found differences in speed but not persistence. Extension of this to include cells within agarose revealed that these cells exhibited less directed migration, but their velocity was unaffected. I showed that cells lacking myosin II failed to complete development within an agarose gel and had significantly reduced velocity and directional migration when compared to their parent strain. Furthermore, the velocities of cells migrating within agarose gel were bimodally distributed, potentially indicating two distinct cell populations, fast and slow, and fast movement was shown to be largely myosin II dependent. Great potential therefore exists for cell-substrate and cell-matrix interactions to affect the migration character of cells, even those, such as Dictyostelium, which do not form strong focal adhesions. Moreover a properly ordered cytoskeleton is implicated in enabling cells to effectively utilise different modes of cell motility.

Imaging from Cells to Animals In Vivo

Author : Margarida Barroso
Publisher : CRC Press
ISBN 13 : 1351704494
Total Pages : 444 pages
Book Rating : 4.3/5 (517 download)

DOWNLOAD NOW!

Book Synopsis Imaging from Cells to Animals In Vivo by : Margarida Barroso

Download or read book Imaging from Cells to Animals In Vivo written by Margarida Barroso and published by CRC Press. This book was released on 2020-12-03 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an overview of imaging techniques used to investigate cells and tissue in their native environment. It covers the range of imaging approaches used, as well as the application of those techniques to the study of biological processes in cells and whole tissues within living organisms.

Development and Application of Optical Coherence Tomography (OCT)

Author : Michael Pircher
Publisher : MDPI
ISBN 13 : 3038427446
Total Pages : 213 pages
Book Rating : 4.0/5 (384 download)

DOWNLOAD NOW!

Book Synopsis Development and Application of Optical Coherence Tomography (OCT) by : Michael Pircher

Download or read book Development and Application of Optical Coherence Tomography (OCT) written by Michael Pircher and published by MDPI. This book was released on 2018-03-23 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Development and Application of Optical Coherence Tomography (OCT)" that was published in Applied Sciences

Optical Coherence Tomography

Author : Wolfgang Drexler
Publisher : Springer Science & Business Media
ISBN 13 : 3540775501
Total Pages : 1346 pages
Book Rating : 4.5/5 (47 download)

DOWNLOAD NOW!

Book Synopsis Optical Coherence Tomography by : Wolfgang Drexler

Download or read book Optical Coherence Tomography written by Wolfgang Drexler and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 1346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.

High Resolution Imaging in Microscopy and Ophthalmology

Author : Josef F. Bille
Publisher : Springer
ISBN 13 : 3030166384
Total Pages : 407 pages
Book Rating : 4.0/5 (31 download)

DOWNLOAD NOW!

Book Synopsis High Resolution Imaging in Microscopy and Ophthalmology by : Josef F. Bille

Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

Optical Coherence Tomography and Its Non-medical Applications

Author : Michael Wang
Publisher : BoD – Books on Demand
ISBN 13 : 1789842611
Total Pages : 226 pages
Book Rating : 4.7/5 (898 download)

DOWNLOAD NOW!

Book Synopsis Optical Coherence Tomography and Its Non-medical Applications by : Michael Wang

Download or read book Optical Coherence Tomography and Its Non-medical Applications written by Michael Wang and published by BoD – Books on Demand. This book was released on 2020-05-27 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is a promising non-invasive non-contact 3D imaging technique that can be used to evaluate and inspect material surfaces, multilayer polymer films, fiber coils, and coatings. OCT can be used for the examination of cultural heritage objects and 3D imaging of microstructures. With subsurface 3D fingerprint imaging capability, OCT could be a valuable tool for enhancing security in biometric applications. OCT can also be used for the evaluation of fastener flushness for improving aerodynamic performance of high-speed aircraft. More and more OCT non-medical applications are emerging. In this book, we present some recent advancements in OCT technology and non-medical applications.

Cell Migration

Author : Jun-Lin Guan
Publisher : Springer Science & Business Media
ISBN 13 : 1592598609
Total Pages : 359 pages
Book Rating : 4.5/5 (925 download)

DOWNLOAD NOW!

Book Synopsis Cell Migration by : Jun-Lin Guan

Download or read book Cell Migration written by Jun-Lin Guan and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of classic, novel, and state-of-the-art methods for the study of cell migration in cultured cells, different model organisms, and specialized cells in normal development and disease. Highlights include basic assays that apply to all cell migration studies in vitro, assays in various model organisms, and assays for cancer cells, endothelial cells, and neurons both in vitro and in animal models. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Optical Coherence Tomography

Author : Mark E. Brezinski
Publisher : Elsevier
ISBN 13 : 0080464947
Total Pages : 645 pages
Book Rating : 4.0/5 (84 download)

DOWNLOAD NOW!

Book Synopsis Optical Coherence Tomography by : Mark E. Brezinski

Download or read book Optical Coherence Tomography written by Mark E. Brezinski and published by Elsevier. This book was released on 2006-08-25 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical Coherence Tomography gives a broad treatment of the subject which will include 1)the optics, science, and physics needed to understand the technology 2) a description of applications with a critical look at how the technology will successfully address actual clinical need, and 3) a discussion of delivery of OCT to the patient, FDA approval and comparisons with available competing technologies. The required mathematical rigor will be present where needed but be presented in such a way that it will not prevent non-scientists and non-engineers from gaining a basic understanding of OCT and the applications as well as the issues of bringing the technology to the market. - Optical Coherence Tomography is a new medical high-resolution imaging technology which offers distinct advantages over current medical imaging technologies and is attracting a large number of researchers. - Provides non-scientists and non-engineers basic understanding of Optical Coherence Tomography applications and issues.

Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (746 download)

DOWNLOAD NOW!

Book Synopsis Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography by :

Download or read book Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Optical Coherence Tomography

Author : Jianbing Xu
Publisher : Open Dissertation Press
ISBN 13 : 9781361349625
Total Pages : pages
Book Rating : 4.3/5 (496 download)

DOWNLOAD NOW!

Book Synopsis Optical Coherence Tomography by : Jianbing Xu

Download or read book Optical Coherence Tomography written by Jianbing Xu and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Optical Coherence Tomography: From System Design to Spectroscopic Applications" by Jianbing, Xu, 徐鉴冰, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Optical coherence tomography (OCT), as a newly developed imaging modality, has attracted significant attention due to its capability to obtain the cross-sectional information of biological tissues in a non-invasive way, with resolution in the range of several micrometers. The third-generation swept source OCT (SS-OCT), is superior in the speed, imaging range and signal-to-noise ratio (SNR) compared with the previous time-domain OCT (TD-OCT) and spectral domain OCT (SD-OCT), and therefore forms our research focus. In this thesis, for the first time, I investigate the deployment of Fourier domain mode-locked (FDML) swept laser by utilizing the bismuth-based erbium doper fiber (Bi-EDF) with a sweeping bandwidth of 81nm achieved. Following, fiber Raman amplifier (FRA) is also investigated by employing multiple Raman pumps. The tuning range is 111.8nm, which is much larger than the previous reported Raman pumped FDML in the 1550nm region. Imaging was performed to validate the feasibility of the proposed schemes for the SS-OCT applications, respectively. In addition to the FDML swept laser cavity design, speckle noise reduction is also of great importance in OCT, which can significantly improve the visibility of the obtained OCT images. I demonstrate two different speckle reduction methods for OCT applications, which are superior in suppressing speckle noise and reserving the one-dimensional (1D) and two-dimensional (2D) signal information, respectively. Applying the proposed wavelet domain compounding (WDC) and contourlet shrinkage method to despeckle the OCT images, the visibility of the OCT images was significantly improved, with negligible edge preservation compromise. Spectroscopic information is also of interest to many researchers as it provides additional spectroscopic contrast, which on one hand, will improve the visualization of the images, and on the other hand, will enable the classification of different tissue types and help the process of discrimination between invasive and noninvasive tumors. Compared with our previous reported work about dual-band spectroscopic OCT based on optical parametric amplifier (OPA) to generate another idler band, which will be used as the second band for dual-band spectroscopic analysis, I further extend the dual-band spectroscopic OCT to the endoscopic applications, and investigate the dual-band FDML swept laser configuration based on a custom-designed dual-channel driver to synchronize the two different wavelength bands, centered at 1310 and 1550 nm, respectively. OCT Images for different bands are captured and post-processed by coding the spectral difference in different colors. In short, in this thesis, the investigations of OCT range from system design, speckle reduction to the spectroscopic applications. All these research efforts will extend the current FDML techniques for a wide range of SS-OCT applications. These schemes may be useful in OCT swept laser source build up, speckle noise reduction, and the extension of spectroscopic analysis. DOI: 10.5353/th_b5317037 Subjects: Optical coherence tomography

Applications of Optical Coherence Tomography in Ophthalmology

Author : Harold Anderson
Publisher : Murphy & Moore Publishing
ISBN 13 : 9781639870530
Total Pages : 243 pages
Book Rating : 4.8/5 (75 download)

DOWNLOAD NOW!

Book Synopsis Applications of Optical Coherence Tomography in Ophthalmology by : Harold Anderson

Download or read book Applications of Optical Coherence Tomography in Ophthalmology written by Harold Anderson and published by Murphy & Moore Publishing. This book was released on 2021-11-16 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography is an imaging test which is non-invasive in nature, and makes use of light waves in order to take cross-section pictures of the retina. The different layers of the retina are visible through this technique. There are numerous eye conditions which can be diagnosed through optical coherence tomography. A few of them are glaucoma, diabetic retinopathy, macular edema and macular hole. The disorders of the optic nerve are also examined using this technique. The conditions which interfere with the passage of light through the eye cannot be diagnosed through optical coherence tomography, since it depends on light waves. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of optical coherence tomography. It strives to provide a fair idea about its clinical applications and to help develop a better understanding of the latest advances within this field. This book is a vital tool for all researching or studying ophthalmology as it gives incredible insights into emerging trends and concepts.

Biological Pigments: Advances in Research and Application: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464922136
Total Pages : 370 pages
Book Rating : 4.4/5 (649 download)

DOWNLOAD NOW!

Book Synopsis Biological Pigments: Advances in Research and Application: 2011 Edition by :

Download or read book Biological Pigments: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Pigments: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological Pigments. The editors have built Biological Pigments: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological Pigments in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Biological Pigments: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Development of a Multi-channel Visible-light Optical Coherence Tomography Platform for Investigating Fibrotic Disease Using Optical Scattering

Download Development of a Multi-channel Visible-light Optical Coherence Tomography Platform for Investigating Fibrotic Disease Using Optical Scattering PDF Online Free

Author : Ryan Niemeier
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (124 download)

DOWNLOAD NOW!

Book Synopsis Development of a Multi-channel Visible-light Optical Coherence Tomography Platform for Investigating Fibrotic Disease Using Optical Scattering by : Ryan Niemeier

Download or read book Development of a Multi-channel Visible-light Optical Coherence Tomography Platform for Investigating Fibrotic Disease Using Optical Scattering written by Ryan Niemeier and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical imaging and microscopy provide multi-dimensional information in both the laboratory and clinical settings. Novel imaging methods have leveraged several contrast sources in order to provide both qualitative and quantitative metrics. Optical coherence tomography (OCT) is a volumetric, micro-scale imaging modality which draws intrinsic contrast from the optical scattering of tissue. Visible-light OCT (VIS-OCT) increases the scattering contrast and is ideal for imaging thin layers of tissue with subtle changes to the optical scattering. The work contained in this dissertation is a modification of VIS-OCT to utilize simultaneous acquisition of multiple channels. Multi-channel VIS-OCT is capable of noise reduction, polarization sensitivity, and quantifying tissue optical scattering. The multi-channel system was used in several imaging applications with relevance to translational medical care and bench-top research. The system was used to image the optical scattering changes in esophageal tissue before and after microwave ablation. Measurements of optical scattering helped to identify the boundaries of the ablation which can provide valuable information both during treatment and for microwave and radiofrequency ablation antenna design. By adding polarization channels, multi-channel VIS-OCT was capable of measuring birefringence in a mouse model of pulmonary fibrosis which is being used to test novel therapeutics for lung disease. Finally, a variation of this OCT system was developed to be used in a multi-modal system which combines and co-registers several other imaging modalities and is well-suited to study fibrosis in glaucoma and cancer. The sensitivity of this VIS-OCT system to optical scattering and polarization effects make it a valuable tool with which to study fibrosis. This dissertation describes the framework of this platform and several utilities which in future work will incorporate a lens-free probe for cost-effective in vivo imaging and other bench-top variations will enable higher resolution imaging capable of capturing dynamic processes in live cells.

OCT Atlas

Author : Nagahisa Yoshimura
Publisher : Springer
ISBN 13 : 9783642386244
Total Pages : 0 pages
Book Rating : 4.3/5 (862 download)

DOWNLOAD NOW!

Book Synopsis OCT Atlas by : Nagahisa Yoshimura

Download or read book OCT Atlas written by Nagahisa Yoshimura and published by Springer. This book was released on 2014-06-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: OCT provided a great advantage over other diagnostic modalities, as it could noninvasively provide tomographic images of the retina of a living eye. As a result, a number of new findings in retinal diseases were made using the time-domain OCT. OCT has now become an essential medical equipment OCT has now become an essential medical equipment in ophthalmic care and quality textbooks describing the functionality of OCT are very important in the education of young ophthalmologists and eye care personnel. In this book are chosen high quality OCT images of rather common diseases as well as images of several rare diseases.

Handbook of Biophotonics

Author : Jürgen Popp
Publisher : John Wiley & Sons
ISBN 13 : 3527410481
Total Pages : 1187 pages
Book Rating : 4.5/5 (274 download)

DOWNLOAD NOW!

Book Synopsis Handbook of Biophotonics by : Jürgen Popp

Download or read book Handbook of Biophotonics written by Jürgen Popp and published by John Wiley & Sons. This book was released on 2011-11-30 with total page 1187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new handbook covers the world of biophotonics not only geographically -- with the editors coming from different continents -- but also in terms of content, since the authors come from the whole spectrum of biophotonic basic and applied research. Designed to set the standard for the scientific community, these three volumes break new ground by providing readers with the physics basics as well as the biological and medical background, together with detailed reports on recent technical advances. The Handbook also adopts an application-related approach, starting with the application and then citing the various tools to solve the scientific task, making it of particular value to medical doctors. Divided into several sections, the first part offers introductory chapters on the different fields of research, with subsequent parts focusing on the applications and techniques in various fields of industry and research. The result is a handy source for scientists seeking the basics in a condensed form, and equally a reference for quickly gathering the knowledge from neighboring disciplines. Absolutely invaluable for biophotonic scientists in their daily work.

Optical Techniques in Regenerative Medicine

Author : Stephen P. Morgan
Publisher : Taylor & Francis
ISBN 13 : 1439854963
Total Pages : 445 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Optical Techniques in Regenerative Medicine by : Stephen P. Morgan

Download or read book Optical Techniques in Regenerative Medicine written by Stephen P. Morgan and published by Taylor & Francis. This book was released on 2016-04-19 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: In regenerative medicine, tissue engineers largely rely on destructive and time-consuming techniques that do not allow in situ and spatial monitoring of tissue growth. Furthermore, once the therapy is implanted in the patient, clinicians are often unable to monitor what is happening in the body. To tackle these barriers, optical techniques have bee

Handbook of Biomedical Optics

Author : David A. Boas
Publisher : CRC Press
ISBN 13 : 1420090372
Total Pages : 816 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Handbook of Biomedical Optics by : David A. Boas

Download or read book Handbook of Biomedical Optics written by David A. Boas and published by CRC Press. This book was released on 2016-04-19 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental