Antioxidants, Cancer and Chemotherapy (Review Article)

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Publisher : GRIN Verlag
ISBN 13 : 3640980689
Total Pages : 10 pages
Book Rating : 4.6/5 (49 download)

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Book Synopsis Antioxidants, Cancer and Chemotherapy (Review Article) by : Mehnaz Mazumdar

Download or read book Antioxidants, Cancer and Chemotherapy (Review Article) written by Mehnaz Mazumdar and published by GRIN Verlag. This book was released on 2011-08-09 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Essay from the year 2011 in the subject Biology - Zoology, Madhab Chandra Das College, Sonai (-), language: English, abstract: The term “antioxidant” coined in 1920 denote substance that fight against any sort of oxidation process (chemical process in which oxygen is caused to combine with other molecules. Most oxidations occur with the liberation of large amounts of energy). The prefix "anti" of the word antioxidants indicate that it works “against” or “in opposition” to the activity of oxidants. Here oxidants indicate free radicals. Free radicals have attracted a great deal of attention in recent years. They are mainly derived from oxygen (reactive oxygen species/ROS) and nitrogen (reactive nitrogen species/RNS), and are generated in our body by various endogenous systems, exposure to different physicochemical conditions or patho- physiological states. Free radicals can adversely alter lipids, proteins and DNA (Deoxyribose nucleic acids) and have been implicated in aging and a number of human diseases including cancer. Antioxidants applications in this regard have become an interesting and introspective arena of research. Antioxidants can fight against these free radicals and protect the body from the various adversaries. When talking of antioxidants, the most widely acclaimed and discussed terminology are the dietary and herbal natural antioxidants which are mostly from plant sources. Scientific evidence strongly holds the promising concept of application of antioxidants against Cancer and also against the side-effects of Cancer Chemotherapy. Antioxidants like Vitamin C, Vitamin E, Quercetin, Curcumin and many others have immense potential to play an important part in Chemotherapy and also in fighting against wide range of cancers. Keywords: Antioxidant; Cancer; Genetic damage; Vitamin C; Vitamin E; Curcumin; Quercetin

Antioxidants Against Cancer

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Publisher :
ISBN 13 : 9781881025283
Total Pages : 0 pages
Book Rating : 4.0/5 (252 download)

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Book Synopsis Antioxidants Against Cancer by : Ralph W. Moss

Download or read book Antioxidants Against Cancer written by Ralph W. Moss and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how antioxidants reduce the side-effects of chemotherapy and may even make it more effective.

Fighting Cancer with Vitamins and Antioxidants

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Publisher : Simon and Schuster
ISBN 13 : 1594778078
Total Pages : 278 pages
Book Rating : 4.5/5 (947 download)

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Book Synopsis Fighting Cancer with Vitamins and Antioxidants by : Kedar N. Prasad

Download or read book Fighting Cancer with Vitamins and Antioxidants written by Kedar N. Prasad and published by Simon and Schuster. This book was released on 2011-10-19 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most up-to-date and complete resource on the powerful benefits of micronutrients for cancer treatment and prevention • Written by the nation’s leading expert on vitamins and cancer research • Reveals how to maximize the benefits of your cancer treatment program while minimizing the side effects of chemotherapy and radiation • Shows how to counteract the carcinogenic effects of dental X-rays, CT scans, mammograms, cell phones, and other unavoidable hazards of modern life • Provides an easy-to-follow program of nutritional supplements to improve your odds of avoiding and beating cancer Despite extensive research and the development of new treatments and drugs, the U.S. mortality rate from cancer has not changed during the past several decades. Yet there are promising nutritional ways of avoiding and even beating cancer. In this completely revised and expanded edition, leading anticancer researcher Kedar N. Prasad and doctor K. Che Prasad reveal the latest revolutionary discoveries in the use of antioxidants and micro-nutrients to prevent and treat cancer--and also help with heart disease, Alzheimer’s, and Parkinson’s. Providing a simple nutritional program to follow, the authors show how micro-nutrients, vitamins, and antioxidants can enhance the beneficial effects of conventional cancer treatments, decrease their toxic side effects, improve long-term prognosis, and reduce the risk of new cancer. Explaining how antioxidants regulate gene expression and cancer heredity, the authors detail how to counteract the risks of dental and medical X-rays, CT scans, mammograms, cell phones, frequent flying, and other unavoidable hazards of modern life; reduce the oxidative stress of free radicals in the blood; and decrease chronic inflammation. Reviewing recent studies, they deflate the controversies surrounding the use of antioxidants in cancer treatment, revealing everything from the reason why many vitamins in foods are destroyed during storage to the surprising role of selenium in cancer prevention.

Nutraceuticals and Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 9400726309
Total Pages : 383 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Nutraceuticals and Cancer by : Fazlul H. Sarkar

Download or read book Nutraceuticals and Cancer written by Fazlul H. Sarkar and published by Springer Science & Business Media. This book was released on 2011-11-22 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.

Dangers of Excessive Antioxidants in Cancer Patients

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Author :
Publisher : Createspace Independent Pub
ISBN 13 : 9781461101000
Total Pages : 514 pages
Book Rating : 4.1/5 (1 download)

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Book Synopsis Dangers of Excessive Antioxidants in Cancer Patients by :

Download or read book Dangers of Excessive Antioxidants in Cancer Patients written by and published by Createspace Independent Pub. This book was released on 2011-06-01 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Howes recommends that patients should be counseled against using antioxidant supplements to prevent or treat cancer. Dr. Howes presents 118 human studies showing antioxidant ineffectiveness in cancer treatment and of this, 39 studies show harmful effects. Dr. Howes presents 27 specific human cancer cell types which are shielded by antioxidants in lab studies and 9 similar murine (rodent) studies. There are over 11 million human participants in these studies, covering over 3 decades. Over 26 studies show that the antioxidants increase the risk of cancer development and 2 studies show that the overall mortality of cancer patients taking antioxidants is increased.

Free Radical Research in Cancer

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Publisher :
ISBN 13 : 9783039360895
Total Pages : 192 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis Free Radical Research in Cancer by : Ana Čipak Gašparović

Download or read book Free Radical Research in Cancer written by Ana Čipak Gašparović and published by . This book was released on 2020 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a great challenge to efficient therapy due to biological diversity. Disturbed oxidative homeostasis in cancer cells certainly contributes to differential therapy response. Further, one of the hallmarks of cancer cells is adaptation which includes fine tuning of the cellular metabolic and signalling pathways as well as transcription profiles. There are several factors which contribute to the tumor diversity and therapy response, and oxidative stress is certainly one of them. Changes in oxygen levels due to hypoxia/reoxygenation during tumor growth modulate antioxidative patterns finally supporting increased cell diversity and adaptation to stressing conditions. Additionally, cancer chemotherapy based on ROS production can also induce also adaptation. To counteract these negative effects natural products are often used for their antioxidant activities as well as photodynamic therapy supported by novel chemosensitizers. Understanding of possible pathways which can trigger antioxidant defence at a certain time during cancer development can also provide possible strategies in fighting cancer.

Inflammation, Oxidative Stress, and Cancer

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Publisher : CRC Press
ISBN 13 : 1466503718
Total Pages : 631 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Inflammation, Oxidative Stress, and Cancer by : Ah-Ng Tony Kong

Download or read book Inflammation, Oxidative Stress, and Cancer written by Ah-Ng Tony Kong and published by CRC Press. This book was released on 2016-04-19 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and

Antioxidant Status, Diet, Nutrition, and Health

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Publisher : CRC Press
ISBN 13 : 1000722627
Total Pages : 694 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Antioxidant Status, Diet, Nutrition, and Health by : Andreas M. Papas

Download or read book Antioxidant Status, Diet, Nutrition, and Health written by Andreas M. Papas and published by CRC Press. This book was released on 2019-10-16 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to integrate the biological, nutritional, and health aspects of antioxidant status. Fifty contributors integrate and transfer the knowledge of free radicals and antioxidants from the test tube to the laboratory of the biologist, clinical nutritionist, and medical researcher, as well as to the office of the dietician, nutritionist, and physician. Topics examined include factors affecting and methods for evaluating antioxidant status in humans; effect of diet and physiological stage (infancy, aging, exercise, alcoholism, HIV infection, etc.) on antioxidant status; and the role of antioxidant status in nutrition, health, and disease.

Cancer

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Publisher : Academic Press
ISBN 13 : 0124055249
Total Pages : 325 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Cancer by : Victor R Preedy

Download or read book Cancer written by Victor R Preedy and published by Academic Press. This book was released on 2014-03-01 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in cancer and then the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component of this. Oncologists, cancer researchers, and nutritionists are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While oncologists and cancer researchers may study the underlying pathogenesis of cancer, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of oncology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of cancer. Nutritionists can apply information related to mitochondrial oxidative stress in one disease to diet-related strategies in another unrelated disease Dietitians can prescribe new foods or diets containing anti-oxidants for conditions resistant to conventional pharmacological treatments Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teams Nutritionists and dietitians will gain an understanding of cell signaling, and be able to suggest new preventative or therapeutic strategies with anti-oxidant rich foods

Cancer

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Publisher : Academic Press
ISBN 13 : 0128195630
Total Pages : 592 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cancer by : Victor R Preedy

Download or read book Cancer written by Victor R Preedy and published by Academic Press. This book was released on 2021-01-14 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer: Oxidative Stress and Dietary Antioxidants, Second Edition, covers the science of oxidative stress in cancer and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor-mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component. Other sections cover new organ site tumors—skin and liver cancer, the role of polymorphisms, cytochrome p450s, COX gene, fatty acids, apoptosis, T cells and mitochondria, prevention/protection with anthocyanins, esculetin, nanoparticles, and more. This book is a valuable resource for cancer researchers, oncologists, nutritionists and other members of the biomedical field who are interested in enhancing treatment outcome, improving the quality of life of patients, and developing new treatments in the fight against cancer. Encompasses updated, revised and state-of-the-art information to advance cancer research Bridges the gaps between nutrition, oxidative stress, and cancer, presenting a holistic approach for health care and research Contains wide applicability to cancer research, from prevention to novel therapeutics

Handbook of Oxidative Stress in Cancer: Therapeutic Aspects

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Publisher : Springer Nature
ISBN 13 : 9811654220
Total Pages : 4078 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Handbook of Oxidative Stress in Cancer: Therapeutic Aspects by : Sajal Chakraborti

Download or read book Handbook of Oxidative Stress in Cancer: Therapeutic Aspects written by Sajal Chakraborti and published by Springer Nature. This book was released on 2022-09-28 with total page 4078 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy. ​

Metronomic Chemotherapy

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Publisher : Springer
ISBN 13 : 3662436043
Total Pages : 302 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Metronomic Chemotherapy by : Guido Bocci

Download or read book Metronomic Chemotherapy written by Guido Bocci and published by Springer. This book was released on 2014-09-04 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.

Antioxidant Overkill

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Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781456547523
Total Pages : 0 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis Antioxidant Overkill by : Phd Randolph M Howes MD

Download or read book Antioxidant Overkill written by Phd Randolph M Howes MD and published by Createspace Independent Publishing Platform. This book was released on 2011-03-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidants from supplements, food sources and the environment have a cumulative effect of dangerously lowering protective prooxidant levels, which "allows" for disease manifestation and coexistence of diseases. Today's marketing of antioxidants is all about sales and has nothing to do with science-based evidence. Scientific data has shown for years that the antioxidant vitamins can increase the risk of cancer, heart disease, stroke and overall mortality. Yet, this information is ignored or denied by those "pushing" these potentially harmful products. None of the synthetic antioxidants work in the same manner as those contained in the biochemical matrix of fruits and vegetables of a nutritious diet. Today's antioxidants should be treated as medicines, not just because of their claims, but because of their proven adverse effects on the human body. I present over 250 scientific studies showing the negligible or non-existent effects of the antioxidants and of these, 80 studies highlight their wide ranging harmful effects. This is the largest collection of its kind in the world's medical literature. The hype of the antioxidants was based on the invalidated and outdated free radical theory, which lacks predictability and fails to meet the requirements of the scientific method. As was pointed out in an article entitled, Antioxidants not heaven sent, by Stefan Andrei Anghel in the Harvard Science Review, Spring 2010, "It may come as a surprise that the current scientific consensus is that there is no health benefit to taking antioxidant supplements. Even more unexpected news came this year when an article announced that antioxidants may actually prevent the health-promoting effects of physical exercise.... If the model proposed by the authors of the study is correct, then it may turn out that we have been systematically "poisoning" ourselves, increasing our disease risk and shortening our lifespan through antioxidant supplements." It was especially gratifying that Anghel cited one of my papers entitled, The Free Radical Fantasy, as the first reference in The Harvard Review and cited it two other times in the article.On January 2 5, 2011, Sharon Begley noted in Newsweek magazine in an article entitled, Antioxidants fall from grace, that, "Now the research is challenging an even more fundamental tenet of the antioxidant craze. Many of the free radicals that are neutralized by antioxidants perform valuable functions in the body. The most important: fighting toxins (white blood cells churn out free radicals by the battalion to fight bacterial infection) and fighting cancer. Maybe it's not such a fabulous idea to flood the body with something that neutralizes these warriors of the immune system." Antioxidant overuse can be dangerous with health problems, like cancer or infections. In 2009, 108 new food products with antioxidants touted on the label reached store shelves, aisles of them in the United States. Shockingly, medical personnel and cancer survivors take more antioxidants than those taken by the average person.The theory behind the use of antioxidants is plausible only if the free radical theory is sound. But, it has been nullified by hundreds of studies. The theory has been wrong and that is the reason that the antioxidant supplements available to us lack effectiveness and produce adverse effects. The free radical theory is pass�!With this explanation, the American Heart Association's advisory statement is sound. There is no good reason, at this point, to spend your money on antioxidant supplements.I have endeavored to find more advanced and improved replacement theories. People are waking up to the fact that they have been victims of clever marketing campaigns, all of which were based on the profit motive.Stop being a victim while the antioxidant craze is dying down. More and more, people are becoming aware of their ineffectiveness and of their harm. The choice is yours. Choose wisely.

Encyclopedia of Dietary Supplements

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Publisher : CRC Press
ISBN 13 : 1498702252
Total Pages : 920 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Encyclopedia of Dietary Supplements by : Paul M. Coates

Download or read book Encyclopedia of Dietary Supplements written by Paul M. Coates and published by CRC Press. This book was released on 2010-06-25 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Dietary Supplements presents peer-reviewed, objective entries that rigorously examine the most significant scientific research on basic chemical, preclinical, and clinical data. Designed for healthcare professionals, researchers, and health-conscious consumers, it presents evidence-based information on the major vitamin and mineral micronutrients, herbs, botanicals, phytochemicals, and other bioactive preparations. Supplements covered include: Vitamins, beta-carotene, niacin, and folate Omega-3 and omega-6 fatty acids, isoflavones, and quercetin Calcium, copper, iron, and phosphorus 5-hydroxytryptophan, glutamine, and L-arginine St. John's Wort, ginkgo biloba, green tea, kava, and noni Androstenedione, DHEA, and melatonin Coenzyme Q10 and S-adenosylmethionine Shiitake, maitake, reishi, and cordiceps With nearly 100 entries contributed by renowned subject-specific experts, the book serves as a scientific checkpoint for the many OTC supplements carried in today's nutritional products marketplace. Also Available Online This Taylor & Francis encyclopedia is also available through online subscription, offering a variety of extra benefits for researchers, students, and librarians, including:  Citation tracking and alerts  Active reference linking  Saved searches and marked lists  HTML and PDF format options Contact Taylor and Francis for more information or to inquire about subscription options and print/online combination packages. US: (Tel) 1.888.318.2367; (E-mail) [email protected] International: (Tel) +44 (0) 20 7017 6062; (E-mail) [email protected]

Herbal Medicine

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Publisher : CRC Press
ISBN 13 : 1439807167
Total Pages : 500 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Herbal Medicine by : Iris F. F. Benzie

Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Inflammation and Cancer

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Publisher : Springer
ISBN 13 : 3034808372
Total Pages : 489 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Inflammation and Cancer by : Bharat B. Aggarwal

Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Colitis-Associated Cancer

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Publisher : Springer
ISBN 13 : 4431555226
Total Pages : 151 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Colitis-Associated Cancer by : Masato Kusunoki

Download or read book Colitis-Associated Cancer written by Masato Kusunoki and published by Springer. This book was released on 2015-10-01 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.