Angiotensin System And Experimental Renal Diseases

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Experimental Models for Renal Diseases

Author : G.A. Herrera
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805595387
Total Pages : 381 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Experimental Models for Renal Diseases by : G.A. Herrera

Download or read book Experimental Models for Renal Diseases written by G.A. Herrera and published by Karger Medical and Scientific Publishers. This book was released on 2011-01-14 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this information has not been available in a single, up-to-date and succinct yet comprehensive source. The publication at hand aims at filling this gap, condensing a vast amount of information into easily accessible chapters.After a discussion of basic concepts and principles of renal tissue reactions to injurious agents using a specific cell/compartment approach, a multitude of disorders are looked at, including renal interstitial fibrosis, glomerulosclerosis, various forms of glomerulonephritis and nephropathy, amyloidosis and renal Fanconi syndrome. Some of the chapters address controversial subjects, reporting the current situation and showing areas of future potential research interest. At the end of many of the contributions, a summary is provided, often in the form of a chart to facilitate the understanding of the information and to make it most useful for didactic purposes.This book is intended for students of various disciplines, as well as clinicians and investigators and all those trying to correlate basic research information with clinical issues.

Kidney and Blood Pressure Regulation

Author : Hiromichi Suzuki (M.D.)
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805577516
Total Pages : 181 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Kidney and Blood Pressure Regulation by : Hiromichi Suzuki (M.D.)

Download or read book Kidney and Blood Pressure Regulation written by Hiromichi Suzuki (M.D.) and published by Karger Medical and Scientific Publishers. This book was released on 2004 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic kidney disease is one of the world's major public health problems, and the prevalence of kidney failure is rising steadily. Among the risk factors for a faster progression of renal disease are hypertension and proteinuria, many studies clearly demonstrating that hypertension is both a cause and consequence of chronic kidney disease. Namely, renal blood pressure regulation seems to be involved in five major pathophysiological mechanisms (all closely related to the renin-angiotensin system): Pressure-natriuresis, renal sympathetic nervous system, renal blood flow, intraglomerular pressure and tubuloglomerular feedback. This book reviews experimental data which form the basis of our current understanding of the association between hypertension and kidney diseases: The pathogenesis of increased blood pressure, the mechanisms by which systemic hypertension promotes progressive kidney failure, and the impact of antihypertensive agents on experimental renal mechanisms involved in hypertension. Furthermore, the role of angiotensin II receptor blockers in both the control of systemic blood pressure and the reduction of proteinuria is examined in an attempt to define optimal therapeutic strategies to prevent the otherwise inexorable deterioration of renal function in patients with chronic kidney disease.

Renal Vascular Disease

Author : Andrew C. Novick
Publisher : Saunders
ISBN 13 :
Total Pages : 566 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Renal Vascular Disease by : Andrew C. Novick

Download or read book Renal Vascular Disease written by Andrew C. Novick and published by Saunders. This book was released on 1996 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a reference text covering all aspects of renal disease, including: pathology, clinical features, imaging, hypertension, atherosclerotic disease, medical and surgical treatment.

The Renin-angiotensin System and Progression of Renal Diseases

Author : Gunter Wolf
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805572751
Total Pages : 278 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis The Renin-angiotensin System and Progression of Renal Diseases by : Gunter Wolf

Download or read book The Renin-angiotensin System and Progression of Renal Diseases written by Gunter Wolf and published by Karger Medical and Scientific Publishers. This book was released on 2001-01-01 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The renin-angiotensin system (RAS) has long been seen as a systemic endocrine system in which angiotensin II (ANG II) is solely involved in blood pressure regulation and the mediation of aldosterone release. However, it is now known that specific organ systems exhibit their own local RAS, functioning for the most part independently from their systemic counterpart. A deluge of data from the last decade has shown that ANG II displays many more functions than just regulating blood pressure: ANG II is a growth factor, exhibits profibrogenic actions, and even serves as a proinflammatory cytokine. It is now clear that this peptide plays a pivotal role in the progression of chronic kidney disease towards endstage renal failure. Clinical studies have provided compelling evidence that interference with ANG II slows this deterioration of renal function.This publication presents the first comprehensive summary of this important topic: Basic concepts as well as clinical aspects of the RAS are reviewed by international experts who made many of the key discoveries that constitute our contemporary understanding of ANG II as a central factor in the progression of renal disease. This publication should be read by physicians treating patients with chronic renal diseases (internists, nephrologists and urologists). Moreover, basic scientists such as renal physiologists, renal pathologists and biochemists who want a comprehensive overview of the subject will profit from reading this book.

Healthy People 2000 Review

Author :
Publisher :
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Healthy People 2000 Review by :

Download or read book Healthy People 2000 Review written by and published by . This book was released on 1995 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Vitamin D in Chronic Kidney Disease

Author : Pablo A. Ureña Torres
Publisher : Springer
ISBN 13 : 3319325078
Total Pages : 583 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Vitamin D in Chronic Kidney Disease by : Pablo A. Ureña Torres

Download or read book Vitamin D in Chronic Kidney Disease written by Pablo A. Ureña Torres and published by Springer. This book was released on 2016-09-21 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an epidemic disease worldwide with more than a billion people suffering of it in the beginning of the 21-century. Besides its impact on mineral and bone metabolism, these low vitamin D levels are also associated with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction. Chronic Kidney Disease is also a very common disease, affecting more than 10% of the world population, ranging from stage 1 to stage 5 before dialysis. Approximately 1% of the population in industrialized countries is affected by end-stage renal disease (ESRD), needing a renal replacement therapy either hemodialysis or peritoneal dialysis, and ultimately by renal transplantation. Those CKD patients are more susceptible to exhibit reduced vitamin D stocks. Consequently, more than eighty percent of CKD patients have either insufficient or deficient vitamin D levels for multiple reasons.

Handbook of Life Course Health Development

Author : Neal Halfon
Publisher : Springer
ISBN 13 : 3319471430
Total Pages : 667 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Handbook of Life Course Health Development by : Neal Halfon

Download or read book Handbook of Life Course Health Development written by Neal Halfon and published by Springer. This book was released on 2017-11-20 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.

Silva's Diagnostic Renal Pathology

Author : Xin J. Zhou
Publisher : Cambridge University Press
ISBN 13 : 1316613984
Total Pages : 691 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Silva's Diagnostic Renal Pathology by : Xin J. Zhou

Download or read book Silva's Diagnostic Renal Pathology written by Xin J. Zhou and published by Cambridge University Press. This book was released on 2017-03-02 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.

Renin Angiotensin System and the Heart

Author : Walmor C. De Mello
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Renin Angiotensin System and the Heart by : Walmor C. De Mello

Download or read book Renin Angiotensin System and the Heart written by Walmor C. De Mello and published by Wiley-Blackwell. This book was released on 2004-04-30 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone. Contains the most recent findings on the renin angiotensin system and the heart Written by an international team of distinguished scientists Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research

The Protective Arm of the Renin Angiotensin System (RAS)

Author : Thomas Unger
Publisher : Academic Press
ISBN 13 : 0128014857
Total Pages : 312 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Protective Arm of the Renin Angiotensin System (RAS) by : Thomas Unger

Download or read book The Protective Arm of the Renin Angiotensin System (RAS) written by Thomas Unger and published by Academic Press. This book was released on 2015-04-18 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. - Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor - Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. - Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases - Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.

New Aspects of the Renin Angiotensin System in Cardiovascular and Renal Diseases

Author : Dulce Elena Casarini
Publisher : Bentham Science Publishers
ISBN 13 : 1681083132
Total Pages : 387 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis New Aspects of the Renin Angiotensin System in Cardiovascular and Renal Diseases by : Dulce Elena Casarini

Download or read book New Aspects of the Renin Angiotensin System in Cardiovascular and Renal Diseases written by Dulce Elena Casarini and published by Bentham Science Publishers. This book was released on 2016-11-03 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: The renin-angiotensin system (RAS) is a hormonal system that is responsible for regulating plasma sodium ion concentration and arterial blood pressure in the body. The system involves several peptides such as angiotensin I and II as well as angiotensin converting enzyme (ACE) to enable the constriction of arterial blood vessels in the lung. Angiotensin II also stimulates the production of the hormone aldosterone in the kidneys which brings sodium ions into the bloodstream in exchange for potassium ions. Malfunctions of the RAS can lead to hypertension, heart failure, diabetes and renal complications. Thus the biochemical components of this system serve as important targets for therapeutic drugs. This monograph is a compilation of updated reviews on the RAS. The monograph covers describes the components of the system to explaining its physiological and clinical features in the cardiovascular system and the kidneys. This is followed by sections explaining the biochemistry of the RAS system in cardiovascular and renal disease and the pharmacology of relevant therapeutic drugs. Additional information on the effect of exercise states and methods to quantify angiotensins for molecular diagnosis is also presented in the concluding sections. Information in the monograph will be of interest to physiologists and endocrinologists involved in medical studies or clinical practice. Readers will be able to understand the RAS with a holistic frame of reference.

Toxicologic Pathology

Author : Pritam S. Sahota
Publisher : CRC Press
ISBN 13 : 1439872120
Total Pages : 987 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Toxicologic Pathology by : Pritam S. Sahota

Download or read book Toxicologic Pathology written by Pritam S. Sahota and published by CRC Press. This book was released on 2013-04-09 with total page 987 pages. Available in PDF, EPUB and Kindle. Book excerpt: As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Saf

Renal Vascular Disease

Author : Lilach O. Lerman
Publisher : Springer Science & Business Media
ISBN 13 : 1447128109
Total Pages : 360 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Renal Vascular Disease by : Lilach O. Lerman

Download or read book Renal Vascular Disease written by Lilach O. Lerman and published by Springer Science & Business Media. This book was released on 2014-03-28 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few references have been published on the renal vascular system and its effect on the cardiovascular system as a whole. Clearly the kidney exerts a huge influence on the circulation and hypertension in particular, but there is a growing concentration on its function across many diseases. This book details the diagnosis, treatment and management of all renal vascular disease.

Experimental Models for Renal Diseases

Author : G. A. Herrera
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805595379
Total Pages : 381 pages
Book Rating : 4.8/5 (55 download)

DOWNLOAD NOW!

Book Synopsis Experimental Models for Renal Diseases by : G. A. Herrera

Download or read book Experimental Models for Renal Diseases written by G. A. Herrera and published by Karger Medical and Scientific Publishers. This book was released on 2010-12-31 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this information has not been available in a single, up-to-date and succinct yet comprehensive source. The publication at hand aims at filling this gap, condensing a vast amount of information into easily accessible chapters. After a discussion of basic concepts and principles of renal tissue reactions to injurious agents using a specific cell/compartment approach, a multitude of disorders are looked at, including renal interstitial fibrosis, glomerulosclerosis, various forms of glomerulonephritis and nephropathy, amyloidosis and renal Fanconi syndrome. Some of the chapters address controversial subjects, reporting the current situation and showing areas of future potential research interest. At the end of many of the contributions, a summary is provided, often in the form of a chart to facilitate the understanding of the information and to make it most useful for didactic purposes. This book is intended for students of various disciplines, as well as clinicians and investigators and all those trying to correlate basic research information with clinical issues.

Hypertension in Postmenopausal Women

Author : Michel E. Safar
Publisher : Springer Science & Business Media
ISBN 13 : 3642790771
Total Pages : 125 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Hypertension in Postmenopausal Women by : Michel E. Safar

Download or read book Hypertension in Postmenopausal Women written by Michel E. Safar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: On the occasion of the symposium on Hypertension in Postmenopausal Women (Monte Carlo, January 19-22, 1994), international scientists and clinicians discussed the various aspects of high blood pressure in older women. This volume presents an overview of this important aspect of both cardiology and gynecology. Special emphasis is given to the different approaches to antihypertension treatment.

The Diabetic Kidney

Author : Pedro Cortes
Publisher : Springer Science & Business Media
ISBN 13 : 1597451533
Total Pages : 553 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis The Diabetic Kidney by : Pedro Cortes

Download or read book The Diabetic Kidney written by Pedro Cortes and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.

Angiotensin

Author : I.H. Page
Publisher : Springer
ISBN 13 : 9783540062769
Total Pages : 594 pages
Book Rating : 4.0/5 (627 download)

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Book Synopsis Angiotensin by : I.H. Page

Download or read book Angiotensin written by I.H. Page and published by Springer. This book was released on 1974-02-14 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of arterial hypertension is both long and short; long, since BRIGHT (1827) first related hardness of the pulse to hardness of the kidneys and hyper. trophy of the heart; short in that modern research began in the late twenties. Most of what we know of these diseases has been discovered in the past fifty years. The modern story should have begun in 1897 when an extract of kidney was shown to be pressor. But little was done with knowledge until about 1929 when the relationship of this kidney extract called "renin" to hypertension was pos· tulated. The pressor effects were, however, unlike most of those seen with sub· stances such as epinephrine or vasopressin. Plasma was required for action of renin and the active substance appeared to be protein. In 1939, it was shown that renin was not in itself a pressor substance but rather a proteolytic enzyme which produced a powerful pressor substance acting on a substrate synthesized by the liver. Later it was noted that the first definable step after the formation of this peptide was cleaving of the decapeptide which had little or no demonstrable activity, with loss of two amino acids to form the octapeptide called "angiotensin". Within a decade synthesis was achieved which made the substance available for world·wide study.