Ancient Dna Typing

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Ancient DNA Typing

Author : Susanne Hummel
Publisher : Springer Science & Business Media
ISBN 13 : 3662050501
Total Pages : 320 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Ancient DNA Typing by : Susanne Hummel

Download or read book Ancient DNA Typing written by Susanne Hummel and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the definitive source of information on techniques for the identification and sequencing of old DNA (pieces) and their use in biological and medical research and application. Application of aDNA techniques are useful tools for investigations reaching from evolutionary studies to law enforcement approaches. What brings them together is the interest in specific methods of handling aDNA, i.e. elaborated PCR and sequencing techniques and the interpretation of the results. This books serves as an ideal guideline for it demonstrates how problem-solving strategies can be applied in various areas.

Ancient DNA

Author : Bernd Herrmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461243181
Total Pages : 275 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Ancient DNA by : Bernd Herrmann

Download or read book Ancient DNA written by Bernd Herrmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ancient DNA refers to DNA which can be recovered and analyzed from clinical, museum, archaeological and paleontological specimens. Ancient DNA ranges in age from less than 100 years to tens of millions of years. The study of ancient DNA is a young field, but it has been revolutionized by the application of polymerase chain reaction technology, and interest is growing very rapidly. Fields as diverse as evolution, anthropology, medicine, agriculture, and even law enforcement have quickly found applications in the recovery of ancient DNA. This book contains contributions from many of the "first generation" researchers who pioneered the development and application of ancient DNA methods. Their chapters present the protocols and precautions which have resulted in the remarkable results obtained in recent years. The range of subjects reflects the wide diversity of applications that are emerging in research on ancient DNA, including the study of DNA to analyze kinship, recovery of DNA from organisms trapped in amber, ancient DNA from human remains preserved in a variety of locations and conditions, DNA recovered from herbarium and museum specimens, and DNA isolated from ancient plant seeds or compression fossils. Ancient DNA will serve as a valuable source of information, ideas, and protocols for anyone interested in this extraordinary field.

Forensic DNA Typing Protocols

Author : Angel Carracedo
Publisher : Springer Science & Business Media
ISBN 13 : 1592598676
Total Pages : 282 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Forensic DNA Typing Protocols by : Angel Carracedo

Download or read book Forensic DNA Typing Protocols written by Angel Carracedo and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art collection of readily reproducible laboratory methods for DNA identity analysis, including Y chromosome haplotyping, mtDNA, and SNP typing. The book offers well-tested protocols for DNA quantification using real-time PCR on forensic samples and for the determination of the number of amelogenine gene copies. For forensic geneticists, there are readily reproducible methods for species identification, ancient DNA, and pharmacogenetics. Additional chapters address new applications in the forensic genetics lab, such a species identification or typing of CYP polymorphisms for the analysis of adverse to drugs.

Forensic DNA Typing: Principles, Applications and Advancements

Author : Pankaj Shrivastava
Publisher : Springer Nature
ISBN 13 : 9811566550
Total Pages : 673 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Forensic DNA Typing: Principles, Applications and Advancements by : Pankaj Shrivastava

Download or read book Forensic DNA Typing: Principles, Applications and Advancements written by Pankaj Shrivastava and published by Springer Nature. This book was released on 2020-12-11 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disaster victim identification, the importance of DNA typing in human trafficking, and various problems associated with capillary electrophoresis. Module 3 emphasizes various technologies that are based on SNPs, STRs namely Y-STR, X-STR, mitochondrial DNA profiling in forensic science. Module 4 explores the application of non-human forensic DNA typing of domestic animals, wildlife forensics, plant DNA fingerprinting, and microbial forensics. The last module discusses new areas and alternative methods in forensic DNA typing, including Next-Generation Sequencing, and its utility in forensic science, oral microbes, and forensic DNA phenotyping. Given its scope, the book is a useful resource in the field of DNA fingerprinting for scientists, forensic experts, and students at the postgraduate level.

Who We Are and How We Got Here

Author : David Reich
Publisher : Oxford University Press
ISBN 13 : 0192554387
Total Pages : 320 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Who We Are and How We Got Here by : David Reich

Download or read book Who We Are and How We Got Here written by David Reich and published by Oxford University Press. This book was released on 2018-03-29 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed a revolution in our ability to obtain DNA from ancient humans. This important new data has added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations living today are mixes of ancient ones, and often carry a genetic component from archaic humans. David Reich, whose team has been at the forefront of these discoveries, explains what genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial âpurity.' Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?

Ancient DNA

Author : Erika Hagelberg
Publisher :
ISBN 13 : 9781782521099
Total Pages : pages
Book Rating : 4.5/5 (21 download)

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Book Synopsis Ancient DNA by : Erika Hagelberg

Download or read book Ancient DNA written by Erika Hagelberg and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ancient DNA

Author : Elizabeth D Jones
Publisher : Yale University Press
ISBN 13 : 030026237X
Total Pages : 279 pages
Book Rating : 4.3/5 (2 download)

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Book Synopsis Ancient DNA by : Elizabeth D Jones

Download or read book Ancient DNA written by Elizabeth D Jones and published by Yale University Press. This book was released on 2022-02-22 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: The untold story of the rise of the new scientific field of ancient DNA research, and how Jurassic Park and popular media influenced its development Ancient DNA research—the recovery of genetic material from long-dead organisms—is a discipline that developed from science fiction into a reality between the 1980s and today. Drawing on scientific, historical, and archival material, as well as original interviews with more than fifty researchers worldwide, Elizabeth Jones explores the field’s formation and explains its relationship with the media by examining its close connection to de-extinction, the science and technology of resurrecting extinct species. She reveals how the search for DNA from fossils flourished under the influence of intense press and public interest, particularly as this new line of research coincided with the book and movie Jurassic Park. Ancient DNA is the first account to trace the historical and sociological interplay between science and celebrity in the rise of this new research field. In the process, Jones argues that ancient DNA research is more than a public-facing science: it is a celebrity science.

Ancient DNA

Author : Beth Alison Shapiro
Publisher :
ISBN 13 : 9781617795169
Total Pages : 247 pages
Book Rating : 4.7/5 (951 download)

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Book Synopsis Ancient DNA by : Beth Alison Shapiro

Download or read book Ancient DNA written by Beth Alison Shapiro and published by . This book was released on 2012-01-01 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ancient DNA presents an overview of the many of the protocols commonly used to study ancient DNA. These include laboratory instructions, extraction protocols, laboratory techniques, and suggestions for appropriate analytical approaches to make sense of the sequences obtained.

Origin

Author : Jennifer Raff
Publisher : Twelve
ISBN 13 : 153874970X
Total Pages : 304 pages
Book Rating : 4.5/5 (387 download)

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Book Synopsis Origin by : Jennifer Raff

Download or read book Origin written by Jennifer Raff and published by Twelve. This book was released on 2022-02-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: AN INSTANT NEW YORK TIMES BESTSELLER! From celebrated anthropologist Jennifer Raff comes the untold story—and fascinating mystery—of how humans migrated to the Americas. ORIGIN is the story of who the first peoples in the Americas were, how and why they made the crossing, how they dispersed south, and how they lived based on a new and powerful kind of evidence: their complete genomes. ORIGIN provides an overview of these new histories throughout North and South America, and a glimpse into how the tools of genetics reveal details about human history and evolution. 20,000 years ago, people crossed a great land bridge from Siberia into Western Alaska and then dispersed southward into what is now called the Americas. Until we venture out to other worlds, this remains the last time our species has populated an entirely new place, and this event has been a subject of deep fascination and controversy. No written records—and scant archaeological evidence—exist to tell us what happened or how it took place. Many different models have been proposed to explain how the Americas were peopled and what happened in the thousands of years that followed. A study of both past and present, ORIGIN explores how genetics is currently being used to construct narratives that profoundly impact Indigenous peoples of the Americas. It serves as a primer for anyone interested in how genetics has become entangled with identity in the way that society addresses the question "Who is indigenous?"

DNA Fingerprinting: Advancements and Future Endeavors

Author : Hirak Ranjan Dash
Publisher : Springer
ISBN 13 : 9811315833
Total Pages : 321 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis DNA Fingerprinting: Advancements and Future Endeavors by : Hirak Ranjan Dash

Download or read book DNA Fingerprinting: Advancements and Future Endeavors written by Hirak Ranjan Dash and published by Springer. This book was released on 2018-11-01 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and the economics of the DNA fingerprinting technique. The book offers a practical guide for professionals, graduate and post-graduate students in the fields of Forensic Science, Medicine, Genetics, Anthropology, Microbiology, and Zoology. It also serves as a useful reference resource, summarizing major technological advances in the field of DNA fingerprinting, the problems faced in this field of science and possible new solutions to these problems. Presently, DNA fingerprinting is utilized in solving the majority of criminal cases; as such, the book is also helpful for investigating agencies, as it includes representative case studies.

Blood Evidence

Author : Henry Lee
Publisher :
ISBN 13 : 0786752300
Total Pages : 453 pages
Book Rating : 4.7/5 (867 download)

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Book Synopsis Blood Evidence by : Henry Lee

Download or read book Blood Evidence written by Henry Lee and published by . This book was released on 2003-04-17 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uses case studies to examine how investigators collect genetic evidence and discusses how DNA has altered crime-solving and the court system as well as the ethical ramifications of cloning, genetic modification, and the death penalty.

Bioinformatics and Functional Genomics

Author : Jonathan Pevsner
Publisher : John Wiley & Sons
ISBN 13 : 0471459178
Total Pages : 792 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Bioinformatics and Functional Genomics by : Jonathan Pevsner

Download or read book Bioinformatics and Functional Genomics written by Jonathan Pevsner and published by John Wiley & Sons. This book was released on 2005-03-04 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.

Handbook of DNA Profiling

Author : Hirak Ranjan Dash
Publisher : Springer
ISBN 13 : 9789811643170
Total Pages : 1206 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis Handbook of DNA Profiling by : Hirak Ranjan Dash

Download or read book Handbook of DNA Profiling written by Hirak Ranjan Dash and published by Springer. This book was released on 2022-06-29 with total page 1206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book comprehensively reviews the significance of DNA technology in forensic science. After presenting the theory, basic principles, tools and techniques that are used in forensic DNA typing, it summarizes various techniques, including autosomal STR, Y-STR, X-STR, mitochondrial DNA and NGS, used in solving both criminal as and civil cases, such as paternity disputes, identification of mutilated remains, and culprit identification in sexual assault and murder cases. It also provides an overview of DNA-based genetic diagnostics for various diseases, and discusses the role of DNA typing in drug reactions, as well as the application of non-human DNA profiling of animals and plants in forensic science investigations. Lastly, the book examines the role of internal quality control in maintaining the high quality of DNA profiling.

DNA Fingerprinting

Author : Lorne T. Kirby
Publisher : Springer
ISBN 13 : 1349120405
Total Pages : 369 pages
Book Rating : 4.3/5 (491 download)

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Book Synopsis DNA Fingerprinting by : Lorne T. Kirby

Download or read book DNA Fingerprinting written by Lorne T. Kirby and published by Springer. This book was released on 1990-06-18 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA fingerprinting is a revolutionary technique that enables law enforcement agencies, diagnostic laboratories and research scientists to identify minute pieces of tissue, to determine parentage and other biological family relationships. This is a study of its applications.

Applied Uses of Ancient DNA

Author : Nic Rawlence
Publisher : Frontiers Media SA
ISBN 13 : 2889669335
Total Pages : 183 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Applied Uses of Ancient DNA by : Nic Rawlence

Download or read book Applied Uses of Ancient DNA written by Nic Rawlence and published by Frontiers Media SA. This book was released on 2021-06-17 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Handbook of Mummy Studies

Author : Dong Hoon Shin
Publisher : Springer
ISBN 13 : 9789811533532
Total Pages : 1171 pages
Book Rating : 4.5/5 (335 download)

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Book Synopsis The Handbook of Mummy Studies by : Dong Hoon Shin

Download or read book The Handbook of Mummy Studies written by Dong Hoon Shin and published by Springer. This book was released on 2021-10-26 with total page 1171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Owing to their unique state of preservation, mummies provide us with significant historical and scientific knowledge of humankind’s past. This handbook, written by prominent international experts in mummy studies, offers readers a comprehensive guide to new understandings of the field’s most recent trends and developments. It provides invaluable information on the health states and pathologies of historic populations and civilizations, as well as their socio-cultural and religious characteristics. Addressing the developments in mummy studies that have taken place over the past two decades – which have been neglected for as long a time – the authors excavate the ground-breaking research that has transformed scientific and cultural knowledge of our ancient predecessors. The handbook investigates the many new biotechnological tools that are routinely applied in mummy studies, ranging from morphological inspection and endoscopy to minimally invasive radiological techniques that are used to assess states of preservation. It also looks at the paleoparasitological and pathological approaches that have been employed to reconstruct the lifestyles and pathologic conditions of ancient populations, and considers the techniques that have been applied to enhance biomedical knowledge, such as craniofacial reconstruction, chemical analysis, stable isotope analysis and ancient DNA analysis. This interdisciplinary handbook will appeal to academics in historical, anthropological, archaeological and biological sciences, and will serve as an indispensable companion to researchers and students interested in worldwide mummy studies.

From Ancient DNA to Forensic Genetics

Author : Frankie Lane West
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis From Ancient DNA to Forensic Genetics by : Frankie Lane West

Download or read book From Ancient DNA to Forensic Genetics written by Frankie Lane West and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In forensic and archaeological applications, degraded DNA presents challenges during extraction, amplification, and analysis. Many of these issues can be addressed through the application of next-generation sequencing (NGS) techniques, including maximizing yields of fragmented DNA and identifying contaminant DNA. NGS is prompting a convergence between ancient and forensic genetic methods along several avenues, including DNA extraction. This dissertation discusses the convergence of extraction techniques contextualized within validation studies of ancient and modern DNA research. Two validation studies are presented. The first study validates and explores the impact of a non-destructive DNA extraction technique developed by Bolnick and colleagues (2012). The “non-destructive” (Bolnick) DNA extraction technique yields both mitochondrial and nuclear DNA. While the teeth tested remained macroscopically intact, there was loss of tooth microstructure in the tooth root and enamel, shown through treated vs. untreated weights and histological analysis. Scanning electron microscopy (SEM) results showed minimal staining of the tooth. There were no significant carbon or oxygen isotopic difference between treated and untreated teeth. The damage characterized shows that the protocol is minimally destructive but may still be of interest to stakeholders desiring maintenance of macroscopic, but not microscopic, integrity. The second study focuses on the quantity and quality of DNA extracted from post-mortem blood samples stored on untreated blood cards. Short-tandem repeats (STRs) typed from the cards are used for ancestry-based analysis. The study validated two different hypotheses: 1) cadaveric blood stored on untreated blood cards yields enough DNA for typing of STRs and 2) STRs typed from blood cards yield geographic ancestry information. Results of the second case study indicate that post-mortem interval impacts the DNA quality of samples extracted from untreated blood cards. Tri-hybrid ancestry and admixture analysis indicate that the original thirteen CODIS loci have utility in estimating geographic ancestry. These validation studies show the complications of working with degraded DNA in both ancient and forensic contexts. NGS approaches provide an opportunity in both fields to move beyond traditional markers to type expansive regions of the genome for both subfields and provides a way of addressing many issues of degraded DNA facing ancient and forensic researchers.