An Investigation Into The Use Of Scattered Photons To Improve 2d Position Emission Tomography Pet Functional Imaging Quality

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An Investigation Into the Use of Scattered Photons to Improve 2D Position Emission Tomography (PET) Functional Imaging Quality

Author : Hongyan Sun
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)

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Book Synopsis An Investigation Into the Use of Scattered Photons to Improve 2D Position Emission Tomography (PET) Functional Imaging Quality by : Hongyan Sun

Download or read book An Investigation Into the Use of Scattered Photons to Improve 2D Position Emission Tomography (PET) Functional Imaging Quality written by Hongyan Sun and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography (PET) is a powerful metabolic imaging modality, which is designed to detect two anti-parallel 511 keV photons origniating from a positron-electron annihilation. However, it is possible that one or both of the annihilation photons undergo a Compton scattering in the object. This is more serious for a scanner operated in 3D mode or with large patients, where the scatter fraction can be as high as 40-60%. When one or both photons are scattered, the line of response (LOR) defined by connecting the two relevant detectors no longer passes through the annihilation position. Thus, scattered coincidences degrade image contrast and compromise quantitative accuracy. Various scatter correction methods have been proposed but most of them are based on estimating and subtracting the scatter from the measured data or incorporating it into an iterative reconstruction algorithm. By accurately measuring the scattered photon energy and taking advantage of the kinematics of Compton scattering, two circular arcs (TCA) in 2D can be identified, which describe the locus of all the possible scattering positions and encompass the point of annihilation. In the limiting case where the scattering angle approaches zero, the TCA approach the LOR for true coincidences. Based on this knowledge, a Generalized Scatter (GS) reconstruction algorithm has been developed in this thesis, which can use both true and scattered coincidences to extract the activity distribution in a consistent way. The annihilation position within the TCA can be further confined by adding a patient outline as a constraint into the GS algorithm. An attenuation correction method for the scattered coincidences was also developed in order to remove the imaging artifacts. A geometrical model that characterizes the different probabilities of the annihilation positions within the TCA was also proposed. This can speed up image convergence and improve reconstructed image quality. Finally, the GS algorithm has been adapted to deal with non-ideal energy resolutions. In summary, an algorithm that implicitly incorporates scattered coincidences into the image reconstruction has been developed. Our results demonstrate that this eliminates the need for scatter correction and can improve system sensitivity and image quality.

Nuclear Oncology

Author : H. William Strauss
Publisher : Springer Science & Business Media
ISBN 13 : 0387488944
Total Pages : 873 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis Nuclear Oncology by : H. William Strauss

Download or read book Nuclear Oncology written by H. William Strauss and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 873 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.

PET and PET/CT

Author : Eugene C. Lin
Publisher : Thieme
ISBN 13 : 1604061545
Total Pages : 320 pages
Book Rating : 4.6/5 (4 download)

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Book Synopsis PET and PET/CT by : Eugene C. Lin

Download or read book PET and PET/CT written by Eugene C. Lin and published by Thieme. This book was released on 2011-01-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for this book:Sure to be a hit -- just like the first edition...All the chapters are well written and the accuracy of information is impressive...[we] cannot recommend the book strongly enough.--RAD MagazineReturning in a second edition, this practical book presents oncological and nononcological applications for PET and PET/CT for the full range of scenarios frequently encountered in the professional setting. Placing special emphasis on PET/CT correlation and FDG oncological imaging, it opens with a thorough introduction to fundamental science and clinical basics. Each chapter in the Oncological Applications section of the book describes the role of PET and PET/CT in the management of specific diseases, providing succinct descriptions of indications and comparisons with other imaging modalities. Highlights: New chapters covering PET/CT for pediatric patients; the use of FDG PET in the evaluation of infection and inflammation; and the role of PET and PET/CT in radiation therapy planning; and FDG biology More than 500 high-quality images, including state-of-the-art color PET/CT images Pearls and pitfalls that emphasize critical concepts Discussion of normal variations and benign findings Thorough review of the current literature on PET/CT This compact book provides readers with the tools to sharpen their assessment and decision-making skills. Organized efficiently to enable rapid reference to key concepts, this concise text is ideal for residents and practitioners in radiology, nuclear medicine, oncology, radiation oncology, and nuclear medicine technology.

99mTc-Sestamibi

Author : Jan Bucerius
Publisher : Springer Science & Business Media
ISBN 13 : 3642042333
Total Pages : 203 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis 99mTc-Sestamibi by : Jan Bucerius

Download or read book 99mTc-Sestamibi written by Jan Bucerius and published by Springer Science & Business Media. This book was released on 2011-09-22 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: 99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that is widely used for the imaging of myocardial perfusion, as well as a variety of malignant and benign diseases. 99mTc-Sestamibi – Clinical Applications provides a detailed and informative overview of almost all the oncologic and non-oncologic applications of 99mTc-sestamibi SPECT, including several relatively rare indications. Different disease-related protocols for 99mTc-sestamibi SPECT are presented, and for each disease a comprehensive summary of the relevant pathology and epidemiology is provided. Throughout, there is a strong emphasis on the practical aspects of use of this popular tracer, including instructions for the preparation of several commercially available tracer kits. Clinical practitioners will find this book to be an invaluable guide to the application and benefits of 99mTc-sestamibi SPECT in both the inpatient and the outpatient setting.

PET/MR: Functional and Molecular Imaging of Neurological Diseases and Neurosciences

Author : Jie Lu
Publisher : Springer Nature
ISBN 13 : 9811999023
Total Pages : 396 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis PET/MR: Functional and Molecular Imaging of Neurological Diseases and Neurosciences by : Jie Lu

Download or read book PET/MR: Functional and Molecular Imaging of Neurological Diseases and Neurosciences written by Jie Lu and published by Springer Nature. This book was released on 2023-05-29 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to summarize the research progress of integrated PET/MR brain function and molecular imaging, and more importantly, clinical application and research status of PET/MR of brain imaging from brain diseases to brain science. Starting from the overviews of brain function imaging technology, following chapters introduces clinical application of integrated PET/MR specific brain diseases in details, such as Alzheimer's disease, Parkinson's disease, epilepsy, and brain tumor, etc., which are hot issues of brain science research. It will be a useful reference to residents and practitioners in nuclear medicine, radiology, and neurology, as well as those interested in molecular imaging of brain.

Positron Emission Tomography

Author : Peter E. Valk
Publisher : Springer Science & Business Media
ISBN 13 : 1846281873
Total Pages : 473 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Positron Emission Tomography by : Peter E. Valk

Download or read book Positron Emission Tomography written by Peter E. Valk and published by Springer Science & Business Media. This book was released on 2006-10-16 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a contemporary reference to the science, technology and clinical applications of PET and PET/CT. The book is designed to be used by residents and fellows training in medical imaging specialties as well as imaging experts in private or academic practice who need to become familiar with this technology and its applications. It is also for use by those whose specialties carry over to PET and PET/CT, referring physicians such as oncologists, cardiologists, neurologists and surgeons. Developed as an offshoot/update of the "clinical practice" portion of the main book, edited by PE Valk et al, published in 2003 (Positron Emission Tomography: basic science and clinical practice), this offshoot covers the second half of the main book only, dealing with mainly the clinical research and practice. Most of the book comprises chapters updated from the "Clinical practice" portion of the main Valk book. It contains 6 brand new chapters and 22 completely revised and updated chapters from the main Valk book.

PET

Author : Michael E. Phelps
Publisher : Springer Science & Business Media
ISBN 13 : 0387349464
Total Pages : 136 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis PET by : Michael E. Phelps

Download or read book PET written by Michael E. Phelps and published by Springer Science & Business Media. This book was released on 2006-12-30 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to give the reader a solid understanding of the physics and instrumentation aspects of PET, including how PET data are collected and formed into an image. Topics include basic physics, detector technology used in modern PET scanners, data acquisition, and 3D reconstruction. A variety of modern PET imaging systems are also discussed, including those designed for clinical services and research, as well as small-animal imaging. Methods for evaluating the performance of these systems are also outlined. The book will interest nuclear medicine students, nuclear medicine physicians, and technologists.

PET/CT in Infection and Inflammation

Author : Thomas Wagner
Publisher : Springer
ISBN 13 : 3319904124
Total Pages : 112 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis PET/CT in Infection and Inflammation by : Thomas Wagner

Download or read book PET/CT in Infection and Inflammation written by Thomas Wagner and published by Springer. This book was released on 2018-08-01 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocket book provides clinicians with the necessary information to understand the role of FDG PET/CT in infection and inflammation. It will help both in making appropriate imaging requests with adequate clinical information and in interpreting the report. The coverage encompasses a wide range of topics, including the role of PET/CT in pyrexia of unknown origin, vasculitis, autoimmune diseases, prosthetic joint infections, osteomyelitis and diabetic foot, immunodeficiency disease, and vascular graft surgery. The book will be a very useful guide to a great test that can provide significant assistance in patient management. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, in which leading professionals succinctly explain the importance of nuclear medicine in the diagnosis and management of oncological and non-oncological conditions.

Positron Emission Tomography

Author : Dale L. Bailey
Publisher : Springer Science & Business Media
ISBN 13 : 1846280079
Total Pages : 381 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Positron Emission Tomography by : Dale L. Bailey

Download or read book Positron Emission Tomography written by Dale L. Bailey and published by Springer Science & Business Media. This book was released on 2006-07-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable. This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters: 2 new (chapters 1, 16) 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18) 3 minor corrections (chapters 2, 6, 11) 5 unchanged (chapters 3, 7, 9, 10, 12)

Particle Physics Reference Library

Author : Christian W. Fabjan
Publisher : Springer Nature
ISBN 13 : 3030353184
Total Pages : 1083 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Particle Physics Reference Library by : Christian W. Fabjan

Download or read book Particle Physics Reference Library written by Christian W. Fabjan and published by Springer Nature. This book was released on 2020 with total page 1083 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second open access volume of the handbook series deals with detectors, large experimental facilities and data handling, both for accelerator and non-accelerator based experiments. It also covers applications in medicine and life sciences. A joint CERN-Springer initiative, the "Particle Physics Reference Library" provides revised and updated contributions based on previously published material in the well-known Landolt-Boernstein series on particle physics, accelerators and detectors (volumes 21A, B1,B2,C), which took stock of the field approximately one decade ago. Central to this new initiative is publication under full open access

Quantitative Nuclear Medicine Imaging

Author : International Atomic Energy Agency
Publisher :
ISBN 13 : 9789201415103
Total Pages : 59 pages
Book Rating : 4.4/5 (151 download)

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Book Synopsis Quantitative Nuclear Medicine Imaging by : International Atomic Energy Agency

Download or read book Quantitative Nuclear Medicine Imaging written by International Atomic Energy Agency and published by . This book was released on 2014 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication reviews the current state of the art of image quantification and provides a solid background of tools and methods to medical physicists and other related professionals who are faced with quantification of radionuclide distribution in clinical practice. It describes and analyses the physical effects that degrade image quality and affect the accuracy of quantification, and describes methods to compensate for them in planar, single-photon emission computed tomography (SPECT) and positron emission tomography (PET) images.

Computed Tomography - E-Book

Author : Euclid Seeram
Publisher : Elsevier Health Sciences
ISBN 13 : 0323323014
Total Pages : 518 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Computed Tomography - E-Book by : Euclid Seeram

Download or read book Computed Tomography - E-Book written by Euclid Seeram and published by Elsevier Health Sciences. This book was released on 2015-09-02 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Build the foundation necessary for the practice of CT scanning with Computed Tomography: Physical Principles, Clinical Applications, and Quality Control, 4th Edition. Written to meet the varied requirements of radiography students and practitioners, this two-color text provides comprehensive coverage of the physical principles of CT and its clinical applications. Its clear, straightforward approach is designed to improve your understanding of sectional anatomic images as they relate to CT — and facilitate communication between CT technologists and other medical personnel. - Comprehensively covers CT at just the right depth for technologists – going beyond superficial treatment to accommodate all the major advances in CT. One complete CT resource covers what you need to know! - The latest information on advances in CT imaging, including: advances in volume CT scanning; CT fluoroscopy; multi-slice applications like 3-D imaging, CT angiography, and virtual reality imaging (endoscopy) – all with excellent coverage of state-of-the-art principles, instrumentation, clinical applications, and quality control. - More than 600 photos and line drawings help students understand and visualize concepts. - Chapter outlines show you what is most important in every chapter. - Strong ancillary package on Evolve facilitates instructor preparation and provides a full complement of support for teaching and learning with the text - NEW! Highlights recent technical developments in CT, such as: the iterative reconstruction; detector updates; x-ray tube innovations; radiation dose optimization; hardware and software developments; and the introduction of a new scanner from Toshiba. - NEW! Learning Objectives and Key Terms at the beginning of every chapter and a Glossary at the end of the book help you organize and focus on key information. - NEW! End-of-Chapter Questions provide opportunity for review and greater challenge. - NEW! An added second color aids in helping you read and retain pertinent information

Basic Science of PET Imaging

Author : Magdy M. Khalil
Publisher : Springer
ISBN 13 : 3319400703
Total Pages : 621 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Basic Science of PET Imaging by : Magdy M. Khalil

Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.

SPECT and SPECT/CT

Author : Chun K. Kim
Publisher : Thieme
ISBN 13 : 162623339X
Total Pages : 355 pages
Book Rating : 4.6/5 (262 download)

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Book Synopsis SPECT and SPECT/CT by : Chun K. Kim

Download or read book SPECT and SPECT/CT written by Chun K. Kim and published by Thieme. This book was released on 2017-06-14 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: FOUR STARS from Doody's Star Ratings™ Internationally renowned authorities in the field of hybrid imaging contribute firsthand expertise on the practical application of single-photon emission computed tomography (SPECT) and SPECT/CT. By combining clear anatomic markers from CT with functional knowledge from SPECT, SPECT/CT provides added value for patient evaluation and is becoming increasingly prevalent in routine clinical practice. Indeed, hybrid imaging is touted by many as a game changer in nuclear medicine. The first two chapters of this book provide a foundation for understanding SPECT and SPECT/CT technological principles, including the associated radiopharmaceuticals. The remaining chapters detail the utility of SPECT and SPECT/CT in clinical practice including neuroscience and pediatrics, as well as specific pathologies. The book concludes with in-depth discussion of select case studies. Key Features Efficacious use of SPECT and SPECT/CT for primary body systems, including the central nervous, cardiovascular, respiratory, and skeletal systems Value for the assessment of neoplastic disease, infection/inflammation, thyroid and parathyroid gland disorders Fourteen high-quality videos delineate specific techniques and clinical applications Meticulous, four-color graphics clearly elucidate key concepts Illustrative case studies offer educational teaching pearls Together, the concise, evidence-based text and wealth of SPECT/CT images deliver a solid knowledge base, enabling practitioners to learn the effective use of this technology. This must-have book is certain to be an invaluable resource for a diverse spectrum of practicing and trainee clinicians in fields such as radiology, nuclear medicine, and radiation oncology.

Ultrafast Ultrasound Imaging

Author : Hideyuki Hasegawa
Publisher : MDPI
ISBN 13 : 3038971278
Total Pages : 185 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Ultrafast Ultrasound Imaging by : Hideyuki Hasegawa

Download or read book Ultrafast Ultrasound Imaging written by Hideyuki Hasegawa and published by MDPI. This book was released on 2018-09-21 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Ultrafast Ultrasound Imaging" that was published in Applied Sciences

Molecular Imaging

Author : Shankar Vallabhajosula
Publisher : Springer Science & Business Media
ISBN 13 : 3540767355
Total Pages : 379 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Molecular Imaging by : Shankar Vallabhajosula

Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

An Introduction to the Physics of Nuclear Medicine

Author : Laura Harkness-Brennan
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643270346
Total Pages : 95 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis An Introduction to the Physics of Nuclear Medicine by : Laura Harkness-Brennan

Download or read book An Introduction to the Physics of Nuclear Medicine written by Laura Harkness-Brennan and published by Morgan & Claypool Publishers. This book was released on 2018-06-27 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complexity and vulnerability of the human body has driven the development of a diverse range of diagnostic and therapeutic techniques in modern medicine. The Nuclear Medicine procedures of Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT) and Radionuclide Therapy are well-established in clinical practice and are founded upon the principles of radiation physics. This book will offer an insight into the physics of nuclear medicine by explaining the principles of radioactivity, how radionuclides are produced and administered as radiopharmaceuticals to the body and how radiation can be detected and used to produce images for diagnosis. The treatment of diseases such as thyroid cancer, hyperthyroidism and lymphoma by radionuclide therapy will also be explored.