mRNA Metabolism & Post-Transcriptional Gene Regulation

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780471142065
Total Pages : 372 pages
Book Rating : 4.1/5 (42 download)

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Book Synopsis mRNA Metabolism & Post-Transcriptional Gene Regulation by : Joe B. Harford

Download or read book mRNA Metabolism & Post-Transcriptional Gene Regulation written by Joe B. Harford and published by John Wiley & Sons. This book was released on 1997-03-28 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: mRNA METABOLISM & POST-TRANSCRIPTIONAL GENE REGULATION Edited by Joe B. Harford and David R. Morris Gene expression is a process that begins with the transcription ofDNA to an RNA messenger (mRNA), which is then translated into aprotein. Historically, attention has been focused on the regulationof RNA synthesis (transcription); however, there is a growingrecognition of and appreciation for the importance of the manyregulatory mechanisms that take place after RNA synthesis has beencompleted. mRNA Metabolism and Post-Transcriptional Gene Regulation is thefirst comprehensive overview of the various modes of generegulation that exist post-transcriptionally. Collecting studies bysome of the top researchers in the field, this volume provides bothan up-to-date review of the complex "life" of an mRNA molecule andan introduction to current work on the diversity of mechanisms ofpost-transcriptional reactions. Topics covered include: * RNA structure * Mammalian RNA editing * RNA export from the nucleus * The fundamentals of translation initiation * Control of mRNA decay in plants * mRNA metabolism and cancer * Control of mRNA stability during herpes simplex virus infection * Regulation of mRNA expression in HIV-1 and other complexretroviruses * Nucleases * RNA localization A timely contribution to the understanding of genetic regulatorymechanisms, mRNA Metabolism and Post-Transcriptional GeneRegulation provides a basis from which potential therapeuticstrategies may be developed. This book will be of vital interest tocell and molecular biologists at all levels, from graduate studentsto senior investigators, clinical researchers, and professionals inthe pharmaceutical and biotechnology industries.

Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities, Volume 2

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Author :
Publisher : CRC Press
ISBN 13 : 1000714667
Total Pages : 292 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities, Volume 2 by : Pia Glas-Greenwalt

Download or read book Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities, Volume 2 written by Pia Glas-Greenwalt and published by CRC Press. This book was released on 2019-11-11 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibrinolysis in Disease reviews the state of the art of basic and clinical aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books. The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities discusses the molecular biology of the system's key components and their fundamental roles in a variety of thrombotic and metabolic disorders. Molecular and Hemovascular Aspects of Fybrinolysis presents the latest findings and concepts of the association between plasminogen activator (u-PA) overexpression and abnormal growth regulation in a variety of solid tumors and in leukemia. One chapter deals with various successful interventions in thrombogenic mechanisms, ranging from exercise and diet to anticoagulants and direct and indirect thrombolytic agents. It concludes with a projection of exciting, novel treatment modalities in thrombotic and malignant diseases.

Control of Messenger RNA Stability

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Author :
Publisher : Elsevier
ISBN 13 : 008091652X
Total Pages : 537 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Control of Messenger RNA Stability by : Joel G. Belasco

Download or read book Control of Messenger RNA Stability written by Joel G. Belasco and published by Elsevier. This book was released on 2012-12-02 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive review of mRNA stability and its implications for regulation of gene expression. Written by experts in the field, Control of Messenger RNA Stability serves both as a reference for specialists in regulation of mRNA stability and as a general introduction for a broader community of scientists. - Provides perspectives from both prokaryotic and eukaryotic systems - Offers a timely, comprehensive review of mRNA degradation, its regulation, and its significance in the control of gene expression - Discusses the mechanisms, RNA structural determinants, and cellular factors that control mRNA degradation - Evaluates experimental procedures for studying mRNA degradation

Regulation of Lymphokine Gene Expression

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Author :
Publisher :
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Regulation of Lymphokine Gene Expression by : Paul Robert Bohjanen

Download or read book Regulation of Lymphokine Gene Expression written by Paul Robert Bohjanen and published by . This book was released on 1993 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sepsis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642850367
Total Pages : 573 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Sepsis by : Konrad Reinhart

Download or read book Sepsis written by Konrad Reinhart and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: The comprehensive coverage of the incidence, etiology, pathophysiology, definition, and therapy of sepsis and septic shock gives you the knowledge you need to keep up with modern therapeutic strategies. The authors are either basic scientists or clinical researchers whose goal is to present the newest aspects of their work in comprehensible language. They clearly show the new perspectives that are emerging in the treatment of sepsis and septic shock.

Oncogenes and Tumor Suppressor Genes in Human Malignancies

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461530881
Total Pages : 390 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Oncogenes and Tumor Suppressor Genes in Human Malignancies by : Christopher Benz

Download or read book Oncogenes and Tumor Suppressor Genes in Human Malignancies written by Christopher Benz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Oncogenes (1989) focused on several of the better known transforming mechanisms and surveyed a spectrum of solid tumors and hematologic malignancies. Several of the nearly 50 known oncogenes most relevant to human disease were examined. In contrast, this volume presents a very different profile and balance of subject material that reflects the rapidly changing field of molecular oncology and its newly emerging concepts. Among the most important discoveries of the past 4 years are the identification of nearly a dozen different tumor suppressor genes and the finding of an entirely new class of cancer-causing gene (bcl-2) that acts by inhibiting cell death rather than stimulating cell proliferation. This edition begins by reviewing selected malignancies in which our earlier search for clinically relevant oncogenes has led to more focused studies on gain-of-function and loss-of-function genetic abnormalities, as well as autocrine and paracrine growth factor loops known to regulate tumor physiology and malignant cell behavior. Curiously, many of these genetic and functional abnormalities are shared by several different tumor types and are not uniformly present in all tumors of the same type. This observation brings up molecular questions about the tissue-specific determinants that underlie individual cancers and also gives added impetus to the suggestion that molecular abnormalities (referred to as tumor markers) be included among the histopathologic features used for clinical diagnosis and manage ment.

Glucocorticoids

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Author :
Publisher : Birkhäuser
ISBN 13 : 303488348X
Total Pages : 205 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Glucocorticoids by : N.J. Goulding

Download or read book Glucocorticoids written by N.J. Goulding and published by Birkhäuser. This book was released on 2012-12-06 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following 50 years of glucocorticoid use in a clinical setting, an international body of expert scientists and physicians presents the most expansive survey of glucocorticoid pharmacology to date. This work traces the history of glucocorticoid biology from the seminal description of glucocorticoid insufficiency by Thomas Addison in the mid-19th century, up to current advances in elucidating the molecular basis of glucocorticoid action. Important discoveries are presented, as well as milestones in drug development, a survey of current clinical practice, and prospects for novel glucocorticoid-based therapeutics. Scientists and clinicians will appreciate the scope of this work, which is of special interest to workers in the fields of endocrinology, inflammation and autoimmune disease.

Angiotensin Vol. I

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783540406402
Total Pages : 576 pages
Book Rating : 4.4/5 (64 download)

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Book Synopsis Angiotensin Vol. I by : E. M. Abdel-Rahman

Download or read book Angiotensin Vol. I written by E. M. Abdel-Rahman and published by Springer Science & Business Media. This book was released on 2004-03-31 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts

Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities

Download Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9780849369391
Total Pages : 352 pages
Book Rating : 4.3/5 (693 download)

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Book Synopsis Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities by : Pia Glas-Greenwalt

Download or read book Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities written by Pia Glas-Greenwalt and published by CRC Press. This book was released on 1995-10-09 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibrinolysis in Disease reviews the state of the art of basic and clinical aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books. The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities discusses the molecular biology of the system's key components and their fundamental roles in a variety of thrombotic and metabolic disorders. Molecular and Hemovascular Aspects of Fybrinolysis presents the latest findings and concepts of the association between plasminogen activator (u-PA) overexpression and abnormal growth regulation in a variety of solid tumors and in leukemia. One chapter deals with various successful interventions in thrombogenic mechanisms, ranging from exercise and diet to anticoagulants and direct and indirect thrombolytic agents. It concludes with a projection of exciting, novel treatment modalities in thrombotic and malignant diseases.

International Journal of Oncology

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Author :
Publisher :
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis International Journal of Oncology by :

Download or read book International Journal of Oncology written by and published by . This book was released on 1997-04 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1384 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1991 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Characterization and Regulation of the Gene Encoding Human Cone Alpha Prime Subunit of Cyclic GMP Phosphodiesterase

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Author :
Publisher :
ISBN 13 :
Total Pages : 274 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis The Characterization and Regulation of the Gene Encoding Human Cone Alpha Prime Subunit of Cyclic GMP Phosphodiesterase by : Andrea Sophia Viczian

Download or read book The Characterization and Regulation of the Gene Encoding Human Cone Alpha Prime Subunit of Cyclic GMP Phosphodiesterase written by Andrea Sophia Viczian and published by . This book was released on 1998 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cytokines: Interleukins and Their Receptors

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461312418
Total Pages : 583 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Cytokines: Interleukins and Their Receptors by : Razelle Kurzrock

Download or read book Cytokines: Interleukins and Their Receptors written by Razelle Kurzrock and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, cytokine research has emerged as one of the most exciting and critical fields for providing fundamental knowledge of normal and abnormal human development. Today, it is apparent that cytokines orchestrate growth from the early embryonic stage to maturity and are responsible for the normal function of virtually every organ system. Furthermore, virtually all disease states have been associated, at least in part, with cytokine aberrations. In this volume, the editors have brought together internationally known experts in the field of interleukin research to provide a comprehensive review of the biology of the interleukins and their role in both health and illness, while maintaining a balance between the basic science and clinical aspects. Cytokines: Interleukins and their Receptors should be of interest to a wide variety of researchers including clinical hematologists, oncologists, immunologists, in addition to medical and PhD students and researchers with an interest in cytokines.

Advances in Pharmacology

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Publisher : Academic Press
ISBN 13 : 0080581196
Total Pages : 377 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Pharmacology by :

Download or read book Advances in Pharmacology written by and published by Academic Press. This book was released on 1994-07-06 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

Identification of Sequences Involved in the Basal Instability and Ras-induced Stabilization of the Vascular Endothelial Growth Factor (VEGF) Transcript

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Author :
Publisher :
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Identification of Sequences Involved in the Basal Instability and Ras-induced Stabilization of the Vascular Endothelial Growth Factor (VEGF) Transcript by : Christopher David Herold

Download or read book Identification of Sequences Involved in the Basal Instability and Ras-induced Stabilization of the Vascular Endothelial Growth Factor (VEGF) Transcript written by Christopher David Herold and published by . This book was released on 2000 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Colony-Stimulating Factors

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Author :
Publisher : CRC Press
ISBN 13 : 1000148459
Total Pages : 588 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Colony-Stimulating Factors by : John M. Garland

Download or read book Colony-Stimulating Factors written by John M. Garland and published by CRC Press. This book was released on 2020-08-26 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). This edition includes eight additional chapters, with updates of recently-discovered and established CSFs, each indexed individually.

Angiotensin Vol. I

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642184952
Total Pages : 547 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Angiotensin Vol. I by : Thomas Unger

Download or read book Angiotensin Vol. I written by Thomas Unger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly thirty years ago, in 1974, the volume on Angiotensin edited by Irvine H.Page and F. Merlin Bumpus expanded the Handbook of Experimental Pharmacology. Even after two decades the multiplicity of its actions appears not to have been fully discovered. To call attention to its many functions is one of the purposes of this book. This new edition of the volume on Angiotensin attempts to provide an updated account of the knowledge and findings accumulated since the complexity of angiotensin was so accurately recognized.