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Author : Elton Trueblood
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (584 download)
Download or read book Alternative to Futility written by Elton Trueblood and published by . This book was released on 1966 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Susan B. Rubin
Publisher : Indiana University Press
ISBN 13 : 9780253112965
Total Pages : 214 pages
Book Rating : 4.1/5 (129 download)
Download or read book When Doctors Say No written by Susan B. Rubin and published by Indiana University Press. This book was released on 1998-10-22 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book is a fine addition to the world of academic medical ethics... Readers... will come away with some of the tools for further debate." -- Publishers Weekly "Susan B. Rubin's splendid new book... offers positive, humane solutions to the frustrations that have given rise to the futility debate." -- Carl Elliott, Medical Humanities Review "Rubin offers a thorough and thought-provoking exploration of the concept of futility as a basis for medical decisions." -- Choice "... [the] brilliant analysis found in Rubin's [book] couldn't be more timely.... When Doctors Say No is the most thorough philosophical rebuttal to be found in the literature of medical futility as the basis for unilateral decisionmaking by physicians." -- Charles Weijer, Canadian Medical Association Journal Should physicians be permitted to unilaterally refuse to provide treatment that they deem futile? Even if the patient, or the patient's family, insists that everything possible must be done? In this book, philosopher and bioethicist Rubin examines this controversial issue. She offers a critique of the concept of medical futility and the debate surrounding it, and she calls for more public debate about the underlying issues at stake for all of us -- patients, families, health care providers, insurers, and society at large.
Author : Troy A. Fritch Sr.
Publisher : AuthorHouse
ISBN 13 : 1496935322
Total Pages : 314 pages
Book Rating : 4.4/5 (969 download)
Download or read book Ecclesiastes written by Troy A. Fritch Sr. and published by AuthorHouse. This book was released on 2014-08-26 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Man has long since sought to become something in this existence called life. He seeks to leave a legacy of remembrance and great achievement behind for generations to follow. But through the Wisdom of Solomon, as given by The Almighty God of Creation, we are to learn that all mans efforts are futile and absolute worthlessness; if God has not been made the central part of your life.
Author : Kelly K. Monroe
Publisher : Zondervan
ISBN 13 : 9780310219224
Total Pages : 372 pages
Book Rating : 4.2/5 (192 download)
Download or read book Finding God at Harvard written by Kelly K. Monroe and published by Zondervan. This book was released on 1997-09-18 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kelly Monroe presents forty-two compelling testimonies from faculty members, former students, and orators at Harvard University whose reflections explode the myth that Christian faith cannot survive a rigorous intellectual environment.
Author : Bernard Ravina
Publisher : Cambridge University Press
ISBN 13 : 1107376572
Total Pages : 387 pages
Book Rating : 4.1/5 (73 download)
Download or read book Clinical Trials in Neurology written by Bernard Ravina and published by Cambridge University Press. This book was released on 2012-04-12 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translating laboratory discoveries into successful therapeutics can be difficult. Clinical Trials in Neurology aims to improve the efficiency of clinical trials and the development of interventions in order to enhance the development of new treatments for neurologic diseases. It introduces the reader to the key concepts underpinning trials in the neurosciences. This volume tackles the challenges of developing therapies for neurologic disorders from measurement of agents in the nervous system to the progression of clinical signs and symptoms through illustrating specific study designs and their applications to different therapeutic areas. Clinical Trials in Neurology covers key issues in Phase I, II and III clinical trials, as well as post-marketing safety surveillance. Topics addressed include regulatory and implementation issues, outcome measures and common problems in drug development. Written by a multidisciplinary team, this comprehensive guide is essential reading for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and clinical researchers in the pharmaceutical industry.
Author : Bo Chen
Publisher : Springer Science & Business Media
ISBN 13 : 3540744495
Total Pages : 540 pages
Book Rating : 4.5/5 (47 download)
Download or read book Combinatorics, Algorithms, Probabilistic and Experimental Methodologies written by Bo Chen and published by Springer Science & Business Media. This book was released on 2007-09-28 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First International Symposium on Combinatorics, Algorithms, Probabilistic and Experimental Methodologies was held in Hangzhou, China, in April 2007. The symposium provided an interdisciplinary forum for researchers to share their discoveries and approaches; search for ideas, methodologies, and tool boxes; find better, faster, and more accurate solutions; and develop a research agenda of common interest. This volume constitutes the refereed post-proceedings of the symposium. Inside you'll find 46 full papers. They represent some of the most important thinking and advancements in the field. The papers address large data processing problems using different methodologies from major disciplines such as computer science, combinatorics, and statistics.
Author : Robert Friedmann
Publisher : Wipf and Stock Publishers
ISBN 13 : 1532632053
Total Pages : 201 pages
Book Rating : 4.5/5 (326 download)
Download or read book Design for Living written by Robert Friedmann and published by Wipf and Stock Publishers. This book was released on 2017-11-29 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in 1954 but unpublished in his lifetime, Robert Friedmann’s Design for Living asks that pertinent existential question: how should we live? Drawing on literary, philosophical, and theological sources, Friedmann’s answer begins with a critique of utilitarian ethics and popular apathy, and proceeds through an existential preparation that ascends in confessional style to the question of the meaning of human life, culminating in a fourfold set of principles: regard, concern, service, and love. Along the way, Friedmann’s critical eye remains clearly fixed on his object of study—lived experience, and not abstract principles detached from day-to-day life—and he intentionally guides his reader step by step up the mountain of spiritual and ethical inquiry in a deliberate and serious attempt to educate the heart, mind, and soul. At once accessible and scholarly, while troubling our contemporary divide between religion and the secular, Design for Living presents a rare vision of human meaning and purpose that will appeal to scholarly and public readers alike.
Author : David Balsley
Publisher : WestBow Press
ISBN 13 : 1490896112
Total Pages : 338 pages
Book Rating : 4.4/5 (98 download)
Download or read book The Puzzled Preacher written by David Balsley and published by WestBow Press. This book was released on 2016-01-25 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why did the Lord see fit to include the book of Ecclesiastes in His inspired Word? Down through the centuries, many people have wondered how Solomon could have moved so far from his walk with the Lord and the wisdom of the Proverbs to the pessimism of Ecclesiastes in one lifetime. For this reason, some have questioned Solomons authorship of the book. But Solomon is only one of many who have taken a spiritual detour in life. As a result, there are many people in our nation and our world who can readily identify with the outlook of Ecclesiastes, because they too are living their lives as Solomon did for a timeunder the sun. This verse-by-verse tour of Solomons experience will help you understand where Solomons spiritual detour took him, and where he finally came to realize he should have been going instead. You will be encouraged to move out from under the sun to the abundance of life in the light of the Son!
Author : Geraldine Rauch
Publisher : Springer
ISBN 13 : 3319737708
Total Pages : 254 pages
Book Rating : 4.3/5 (197 download)
Download or read book Planning and Analyzing Clinical Trials with Composite Endpoints written by Geraldine Rauch and published by Springer. This book was released on 2018-05-22 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the most important aspects of how to plan and evaluate clinical trials with a composite primary endpoint to guarantee a clinically meaningful and valid interpretation of the results. Composite endpoints are often used as primary efficacy variables for clinical trials, particularly in the fields of oncology and cardiology. These endpoints combine several variables of interest within a single composite measure, and as a result, all variables that are of major clinical relevance can be considered in the primary analysis without the need to adjust for multiplicity. Moreover, composite endpoints are intended to increase the size of the expected effects thus making clinical trials more powerful. The book offers practical advice for statisticians and medical experts involved in the planning and analysis of clinical trials. For readers who are mainly interested in the application of the methods, all the approaches are illustrated with real-world clinical trial examples, and the software codes required for fast and easy implementation are provided. The book also discusses all the methods in the context of relevant guidelines related to the topic. To benefit most from the book, readers should be familiar with the principles of clinical trials and basic statistical methods.
Author : Susan Halabi
Publisher : CRC Press
ISBN 13 : 1351620967
Total Pages : 708 pages
Book Rating : 4.3/5 (516 download)
Download or read book Textbook of Clinical Trials in Oncology written by Susan Halabi and published by CRC Press. This book was released on 2019-04-24 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area. The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology. Key Features: Cutting-edge topics with appropriate technical background Built around case studies which give the work a "hands-on" approach Real examples of flaws in previously reported clinical trials and how to avoid them Access to statistical code on the book’s website Chapters written by internationally recognized statisticians from academia and pharmaceutical companies Carefully edited to ensure consistency in style, level, and approach Topics covered include innovating phase I and II designs, trials in immune-oncology and rare diseases, among many others
Author : Norman C. Habel
Publisher : Westminster John Knox Press
ISBN 13 : 1611645182
Total Pages : 590 pages
Book Rating : 4.6/5 (116 download)
Download or read book The Book of Job (OTL) written by Norman C. Habel and published by Westminster John Knox Press. This book was released on 1985-05-01 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, Norman Habel takes on the humbling task of writing a commentary on such a classic work as the book of Job--a text that is complex and unclear at many points. The Old Testament Library provides fresh and authoritative treatments of important aspects of Old Testament study through commentaries and general surveys. The contributors are scholars of international standing.
Author : Marjorie Bass Zucker
Publisher : Cambridge University Press
ISBN 13 : 9780521568777
Total Pages : 224 pages
Book Rating : 4.5/5 (687 download)
Download or read book Medical Futility written by Marjorie Bass Zucker and published by Cambridge University Press. This book was released on 1997-03-13 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: A wide-ranging and authoritative survey of the complex issue of futile medical treatments.
Author : Patricia R. Batchelor Chess
Publisher : Elsevier Health Sciences
ISBN 13 : 0443106843
Total Pages : 594 pages
Book Rating : 4.4/5 (431 download)
Download or read book Avery's Neonatology Board Review E-Book written by Patricia R. Batchelor Chess and published by Elsevier Health Sciences. This book was released on 2024-02-26 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ace your neonatology board exams and prepare for clinical practice with Avery's Neonatology Board Review: Certification and Clinical Refresher, 2nd Edition. This up-to-date review tool follows the exam blueprint, is based on the trusted content found in Avery's Diseases of the Newborn, and has been carefully tailored for effective exam review by renowned neonatologist and educator, Patricia Batchelor Chess, MD. Concise, relevant information is presented in a way that's easy to study and remember, giving you an important advantage on this challenging exam, as well as in the daily, fast-changing practice of neonatology.The most up-to-date, thorough, and effective board review book for neonatology . . . - Equips residents, fellows, and attending physicians with an efficient, comprehensive system for study, designed specifically to optimize performance on the board exam. - Presents information in a high-yield, outline format highlighted by key points, graphs, tables, images, and algorithms. - Includes expanded content on pulmonary mechanisms and on diversity and equity, reflecting the newly revised board exam core content outline. - Contains more than 450 board-style questions and answers, both in print and interactively online, related to each chapter. - Features board-style vignettes with full, discursive answers online. - Written by experts in the field of Neonatal-Perinatal Medicine and supporting subspecialists, representing a wealth of trusted insight and guidance.
Author : Steven Piantadosi
Publisher : Springer Nature
ISBN 13 : 3319526367
Total Pages : 2573 pages
Book Rating : 4.3/5 (195 download)
Download or read book Principles and Practice of Clinical Trials written by Steven Piantadosi and published by Springer Nature. This book was released on 2022-07-19 with total page 2573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.
Author : John Crowley
Publisher : CRC Press
ISBN 13 : 1439862001
Total Pages : 661 pages
Book Rating : 4.4/5 (398 download)
Download or read book Handbook of Statistics in Clinical Oncology, Third Edition written by John Crowley and published by CRC Press. This book was released on 2012-03-26 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been exploding. Inclusion of high-dimensional data and imaging techniques have become common practice, and statistical methods on how to analyse such data have been refined in this area. A compilation of statistical topics relevant to these new advances in cancer research, this third edition of Handbook of Statistics in Clinical Oncology focuses on the design and analysis of oncology clinical trials and translational research. Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials, incorporating updates to all four parts: Phase I trials: Updated recommendations regarding the standard 3 + 3 and continual reassessment approaches, along with new chapters on phase 0 trials and phase I trial design for targeted agents. Phase II trials: Updates to current experience in single-arm and randomized phase II trial designs. New chapters include phase II designs with multiple strata and phase II/III designs. Phase III trials: Many new chapters include interim analyses and early stopping considerations, phase III trial designs for targeted agents and for testing the ability of markers, adaptive trial designs, cure rate survival models, statistical methods of imaging, as well as a thorough review of software for the design and analysis of clinical trials. Exploratory and high-dimensional data analyses: All chapters in this part have been thoroughly updated since the last edition. New chapters address methods for analyzing SNP data and for developing a score based on gene expression data. In addition, chapters on risk calculators and forensic bioinformatics have been added. Accessible to statisticians and oncologists interested in clinical trial methodology, the book is a single-source collection of up-to-date statistical approaches to research in clinical oncology.
Author : Michael D Rawlins
Publisher : CRC Press
ISBN 13 : 1853159476
Total Pages : 246 pages
Book Rating : 4.8/5 (531 download)
Download or read book Therapeutics, Evidence and Decision-Making written by Michael D Rawlins and published by CRC Press. This book was released on 2011-07-29 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to help decision-makers use, assess and appraise the evidence that underpins decisions about the use of therapeutic interventions. It will inform decision-makers about the nature of evidence, the strengths and weaknesses of the available approaches, and how these can be most effectively distilled for the purpose of reaching reliable conclusions. It aims to encourage decision-makers to base their judgements about the use of therapeutic interventions on an informed appraisal of the totality of the evidence base. Is it reliable? Is it generalisable beyond the context of the environment in which the primary research has been conducted? Do the intervention's benefits outweigh its harms? Is it cost effective as well as clinically effective? Is it, indeed, fit-for-purpose? Ultimately, good judgement is at the heart of decision-making in therapeutics. An invaluable text for all physicians, pharmacists, nurses, health commissioners and purchasers and indeed anyone having to make decisions concerning evidence-based therapeutics.
Author : David Orentlicher
Publisher : Princeton University Press
ISBN 13 : 0691227667
Total Pages : 247 pages
Book Rating : 4.6/5 (912 download)
Download or read book Matters of Life and Death written by David Orentlicher and published by Princeton University Press. This book was released on 2021-03-09 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophical debates over the fundamental principles that should guide life-and-death medical decisions usually occur at a considerable remove from the tough, real-world choices made in hospital rooms, courthouses, and legislatures. David Orentlicher seeks to change that, drawing on his extensive experience in both medicine and law to address the translation of moral principle into practice--a move that itself generates important moral concerns. Orentlicher uses controversial life-and-death issues as case studies for evaluating three models for translating principle into practice. Physician-assisted suicide illustrates the application of ''generally valid rules,'' a model that provides predictability and simplicity and, more importantly, avoids the personal biases that influence case-by-case judgments. The author then takes up the debate over forcing pregnant women to accept treatments to save their fetuses. He uses this issue to weigh the ''avoidance of perverse incentives,'' an approach to translation that follows principles hesitantly for fear of generating unintended results. And third, Orentlicher considers the denial of life-sustaining treatment on grounds of medical futility in his evaluation of the ''tragic choices'' model, which hides difficult life-and-death choices in order to prevent paralyzing social conflict. Matters of Life and Death is a rich and stimulating contribution to bioethics and law. It is the first book to examine closely the broad problems of translating principle into practice. And by analyzing specific controversies along the way, it develops original insights likely to provoke both moral philosophers and those working on thorny issues of life and death.
