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Altered Metabolism A Major Contributor Of Comorbidities In Neurodegenerative Diseases
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Book Synopsis Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases by : Namita Agrawal
Download or read book Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases written by Namita Agrawal and published by Springer Nature. This book was released on with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Oxford Textbook of Cognitive Neurology and Dementia by : Masud Husain
Download or read book Oxford Textbook of Cognitive Neurology and Dementia written by Masud Husain and published by Oxford University Press. This book was released on 2018-10-29 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.
Book Synopsis Apolipoprotein E and Alzheimer’s Disease by : A.D. Roses
Download or read book Apolipoprotein E and Alzheimer’s Disease written by A.D. Roses and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new filed, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic management of Alzheimer's disease.
Book Synopsis Dementia with Lewy Bodies by : John O'Brien
Download or read book Dementia with Lewy Bodies written by John O'Brien and published by CRC Press. This book was released on 2005-11-29 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder
Book Synopsis Metformin: Beyond Diabetes by : Frederic Bost
Download or read book Metformin: Beyond Diabetes written by Frederic Bost and published by Frontiers Media SA. This book was released on 2020-01-24 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabolic Alterations in Neurodegenerative Disorders by : David Baglietto-Vargas
Download or read book Metabolic Alterations in Neurodegenerative Disorders written by David Baglietto-Vargas and published by Frontiers Media SA. This book was released on 2022-03-14 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sleep Disorders and Sleep Deprivation by : Institute of Medicine
Download or read book Sleep Disorders and Sleep Deprivation written by Institute of Medicine and published by National Academies Press. This book was released on 2006-10-13 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.
Book Synopsis Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America by : Agustín Ibáñez
Download or read book Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America written by Agustín Ibáñez and published by Frontiers Media SA. This book was released on 2018-06-21 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.
Book Synopsis Ketogenic Diet and Metabolic Therapies by : Susan Masino
Download or read book Ketogenic Diet and Metabolic Therapies written by Susan Masino and published by Oxford University Press. This book was released on 2016-11-17 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ketogenic Diet and Metabolic Therapies is the first comprehensive scientific resource on the ketogenic diet, covering the latest research including the biomedical mechanisms, established and emerging applications, metabolic alternatives, and implications for health and disease. Experts in clinical and basic research share their research into mechanisms spanning from ion channels to epigenetics, their insights based on decades of experience with the ketogenic diet in epilepsy, and their evidence for emerging applications ranging from autism to Alzheimer's disease to brain cancer. Research in metabolic therapies has spread into laboratories and clinics of every discipline, and is yielding to entirely new classes of drugs and treatment regimens.
Book Synopsis Enteric Glia by : Brian D. Gulbransen
Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography
Book Synopsis Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders by : Paul C. Guest
Download or read book Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders written by Paul C. Guest and published by Springer. This book was released on 2019-02-12 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.
Book Synopsis Oxidative Stress and Neurodegenerative Disorders by : G. Ali Qureshi
Download or read book Oxidative Stress and Neurodegenerative Disorders written by G. Ali Qureshi and published by Elsevier. This book was released on 2007-03-22 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders.* Contains the latest information on the subject of neurodegenerative disorders* Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems
Book Synopsis Limbic-predominant Age-related TDP-43 Encephalopathy by : Beller Health
Download or read book Limbic-predominant Age-related TDP-43 Encephalopathy written by Beller Health and published by Independently Published. This book was released on 2019-05-13 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book 9 focuses on a new dementia type, LATE, mistaken as Alzheimer's disease until now.LATE stands for Limbic-predominant age-related TDP-43 encephalopathy, the protein buildup responsible for this dementia. This book is organic, like the series, meaning we never consider our books as finished. Science evolves, which is why our books go through continuous updates. Since LATE is a new dementia classification, we expect continuous further information to emerge. Watch Amazon alerts for potential digital updates. We provide free digital copies on all paperback purchases, so everybody receives free updates.
Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash
Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Book Synopsis Lipid Metabolism and Transport in CNS Health and Disease by : Kimberley D. Bruce
Download or read book Lipid Metabolism and Transport in CNS Health and Disease written by Kimberley D. Bruce and published by Frontiers Media SA. This book was released on 2021-12-07 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis High Calorie Diet and the Human Brain by : Akhlaq A. Farooqui
Download or read book High Calorie Diet and the Human Brain written by Akhlaq A. Farooqui and published by Springer. This book was released on 2015-03-25 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this monograph is to present readers with a comprehensive and cutting edge description of neurochemical effects of diet (beneficial and harmful effects) in normal human brain and to discuss how present day diet promotes pathogenesis of stroke, AD, PD, and depression in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. A diet in sufficient amount and appropriate macronutrients is essential for optimal health of human body tissues. In brain, over-nutrition, particularly with high-calorie diet, not only alters cellular homeostasis, but also results in changes in the intensity of signal transduction processes in reward centers of the brain resulting in food addiction. Over-nutrition produces detrimental effects on human health in general and brain health in particular because it chronically increases the systemic and brain inflammation and oxidative stress along with induction of insulin resistance and leptin resistance in the brain as well as visceral organs. Onset of chronic inflammation and oxidative stress not only leads to obesity and heart disease, but also promotes type II diabetes and metabolic syndrome, which are risk factors for both acute neural trauma (stroke) and chronic age-related neurodegenerative and neuropsychological disorders, such as Alzheimer disease (AD), Parkinson disease (PD) and depression.
Book Synopsis Diabetes and the Nervous System by : Douglas W. Zochodne
Download or read book Diabetes and the Nervous System written by Douglas W. Zochodne and published by Elsevier. This book was released on 2014-12-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson's disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system.
