Alpha 1 Antitrypsin

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Alpha-1-antitrypsin Deficiency

Author : Noor Kalsheker
Publisher : Academic Press
ISBN 13 : 0128039477
Total Pages : 262 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Alpha-1-antitrypsin Deficiency by : Noor Kalsheker

Download or read book Alpha-1-antitrypsin Deficiency written by Noor Kalsheker and published by Academic Press. This book was released on 2017-06-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research. The book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. The editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease. - Provides documentation of the variations in clinical presentation and pathology in a single reference - Presents new insights by pulling together the advances in the understanding of the structure and function of alpha1-antitrypsin deficiency with the genetic variants that cause the disease - Allows for easy reference for the diagnosis of AATD to lead to better therapeutics

Living with Alpha-1 Antitrypsin Deficiency (A1AD)

Author : Samantha Bowick
Publisher : Hatherleigh Press
ISBN 13 : 1578268109
Total Pages : 80 pages
Book Rating : 4.5/5 (782 download)

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Book Synopsis Living with Alpha-1 Antitrypsin Deficiency (A1AD) by : Samantha Bowick

Download or read book Living with Alpha-1 Antitrypsin Deficiency (A1AD) written by Samantha Bowick and published by Hatherleigh Press. This book was released on 2019-08-27 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: BEST BOOK AWARD 2019 FINALIST - HEALTH: GENERAL (AMERICAN BOOK FEST) A knowledgeable handbook with a patient's perspective for those afflicted with the incurable disease known as Alpha-1 Antitrypsin deficiency (A1AD). Alpha-1 Antitrypsin deficiency (A1AD) is a rare genetic, incurable disease which causes the liver to not produce enough of a certain protein that protects and keeps the lungs functional. 100,000 people in the United States have A1AD and 19 million more are carriers for the disease. Since it's so rare, the information available about A1AD has been lacking especially for those suffering unknowingly with the disease. Living with Alpha-1 Antitrypsin Deficiency offers the most up-to-date and comprehensive information on this illness and includes first-hand experience from someone managing the disease. Living with Alpha-1 Antitrypsin Deficiency also includes expert advice from doctors and researchers tackling the disease, with tips on recognizing symptoms and getting the most effective help possible.

Alpha-1-Antitrypsin Deficiency

Author : Pavel Strnad
Publisher : European Respiratory Society
ISBN 13 : 1849841098
Total Pages : 211 pages
Book Rating : 4.8/5 (498 download)

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Book Synopsis Alpha-1-Antitrypsin Deficiency by : Pavel Strnad

Download or read book Alpha-1-Antitrypsin Deficiency written by Pavel Strnad and published by European Respiratory Society. This book was released on 2019-09-01 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Monograph offers a comprehensive and up-to-date overview of AATD. It covers basic biology, genetics, laboratory diagnostics and the major organ manifestations; describes the clinical presentation of AATD in both adults and children; and features chapters on genetic counselling, patient views and future therapies. The content has been tailored to meet the needs of the physician, who takes care of lung and liver patients in daily practice, and the general practitioner, who is responsible for the medical guidance of these patients.

Syndromes: Rapid Recognition and Perioperative Implications

Author : Bruno Bissonnette
Publisher : McGraw-Hill Education / Medical
ISBN 13 :
Total Pages : 988 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Syndromes: Rapid Recognition and Perioperative Implications by : Bruno Bissonnette

Download or read book Syndromes: Rapid Recognition and Perioperative Implications written by Bruno Bissonnette and published by McGraw-Hill Education / Medical. This book was released on 2006-08-10 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential medical facts on over 2,000 genetic syndromes. Organized alphabetically, this book provides comprehensive medical coverage for each syndrome, from genetic basis to manifestations to related medical considerations.

Alpha-1-Antitrypsin Deficiency

Author : Florie Borel
Publisher : Humana Press
ISBN 13 : 9781493971619
Total Pages : 278 pages
Book Rating : 4.9/5 (716 download)

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Book Synopsis Alpha-1-Antitrypsin Deficiency by : Florie Borel

Download or read book Alpha-1-Antitrypsin Deficiency written by Florie Borel and published by Humana Press. This book was released on 2017-08-08 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols that expand on the latest alpha-1-antitrypsin (AAT) research. The chapters in this book are divided in to three sections: Part I is dedicated to patient-oriented research; part II discusses animal models; and Part III focuses on in vitro studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Alpha-1 Antitrypsin Deficiency: Methods and Protocols is a valuable resource for researchers, students, and clinican-scientists interested in AAT deficiency, as well as anyone working in the fields of pulmonology and hepatology.

Controversies in COPD

Author : Antonio Anzueto
Publisher : European Respiratory Society
ISBN 13 : 1849840644
Total Pages : 341 pages
Book Rating : 4.8/5 (498 download)

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Book Synopsis Controversies in COPD by : Antonio Anzueto

Download or read book Controversies in COPD written by Antonio Anzueto and published by European Respiratory Society. This book was released on 2015-09-01 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: COPD is one of the most common diseases worldwide and is projected to be the third leading cause of death by 2020. But that does not mean it is easy to understand or manage. In everyday practice, pulmonologists face areas of controversy in COPD, for which evidence-based medicine is often unavailable. This ERS Monograph considers where the current controversies in COPD lie, discussing areas such as screening, premature birth, asthma–COPD overlap syndrome, treatment, rehabilitation and palliative care. This book will be of great interest to both clinicians and scientists, and aims to stimulate further discussion about this diverse and fascinating disease. "...contains a vast amount of information on the disease, its prevalence, signs and symptoms, diagnositc tests and treatment options. The book's format makes it quick and simple to find out what you need to know, and its size would make it easy to take to work for use in practice [...] invaluable for anyone working with patients with the disease." Emma Vincent, Nursing Standard

Practical Gastroenterology and Hepatology Board Review Toolkit

Author : Kenneth R. DeVault
Publisher : John Wiley & Sons
ISBN 13 : 1118829085
Total Pages : 680 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Practical Gastroenterology and Hepatology Board Review Toolkit by : Kenneth R. DeVault

Download or read book Practical Gastroenterology and Hepatology Board Review Toolkit written by Kenneth R. DeVault and published by John Wiley & Sons. This book was released on 2016-07-21 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Packed with Board-focused hints, case studies and an onlineBoard-standard MCQ test offering CME credits, this fantastic bookcovers every gastroenterology disease and symptom you’relikely to encounter and is the perfect tool to prepare for Boardexams and certification.

Alpha-1 Antitrypsin Deficiency

Author : Thomas Köhnlein
Publisher : UNI-MED Verlag AG
ISBN 13 : 1848151152
Total Pages : 106 pages
Book Rating : 4.8/5 (481 download)

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Book Synopsis Alpha-1 Antitrypsin Deficiency by : Thomas Köhnlein

Download or read book Alpha-1 Antitrypsin Deficiency written by Thomas Köhnlein and published by UNI-MED Verlag AG. This book was released on 2007 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Pathobiochemistry

Author : Toshitaka Oohashi
Publisher : Springer
ISBN 13 : 981132977X
Total Pages : 349 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Human Pathobiochemistry by : Toshitaka Oohashi

Download or read book Human Pathobiochemistry written by Toshitaka Oohashi and published by Springer. This book was released on 2019-03-13 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.

Am I My Genes?

Author : Robert L. Klitzman M.D.
Publisher : Oxford University Press
ISBN 13 : 0190207671
Total Pages : 376 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Am I My Genes? by : Robert L. Klitzman M.D.

Download or read book Am I My Genes? written by Robert L. Klitzman M.D. and published by Oxford University Press. This book was released on 2012-03-01 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fifty years since DNA was discovered, we have seen extraordinary advances. For example, genetic testing has rapidly improved the diagnosis and treatment of diseases such as Huntington's, cystic fibrosis, breast cancer, and Alzheimer's. But with this new knowledge comes difficult decisions for countless people, who wrestle with fear about whether to get tested, and if so, what to do with the results. Am I My Genes? shows how real individuals have confronted these issues in their daily lives. Robert L. Klitzman interviewed 64 people who faced Huntington's Disease, breast and ovarian cancer, or Alpha-1 antitrypsin deficiency. The book describes--often in the person's own words--how each has wrestled with the vast implications that genetics has for their lives and their families. Klitzman shows how these men and women struggle to make sense of their predicament and its causes. They confront a series of quandaries--whether to be tested; whether to disclose their genetic risks to parents, siblings, spouses, offspring, friends, doctors, insurers, employers, and schools; how to view and understand themselves and their genetics; what treatments, if any, to pursue; whether to have children, adopt, screen embryos, or abort; and whether to participate in genetic communities. In the face of these uncertainties, they have tried to understand these tests and probabilities, avoid fatalism, anxiety, despair, and discrimination, and find hope, meaning, and a sense of wholeness. Forced to wander through a wilderness of shifting sands, they chart paths that many others may eventually follow. Klitzman captures here the voices of pioneers, some of the first to encounter the personal dilemmas introduced by modern genetics. Am I My Genes? is an invaluable account of their experience, one that will become all the more common in the coming years. "An extraordinary exploration...probing the many roles and implications of genetics in our lives today.... Filled with astonishing insights, this riveting book is vital reading for us all." --Paula Zahn "Klitzman lucidly discusses the moral and psychological complexities that come in the wake of genetic testing.... An important book for anyone who has the genes for pathology, which is all of us, and I recommend it highly." --Kay Redfield Jamison, author of An Unquiet Mind "An illuminating voyage through the medical, familial and existential quandaries faced by those of us at genetic risk." --Thomas H. Murray, President and CEO, The Hastings Center

Pouchitis and Ileal Pouch Disorders

Author : Bo Shen
Publisher : Academic Press
ISBN 13 : 0128096292
Total Pages : 574 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Pouchitis and Ileal Pouch Disorders by : Bo Shen

Download or read book Pouchitis and Ileal Pouch Disorders written by Bo Shen and published by Academic Press. This book was released on 2018-11-05 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pouchitis and Ileal Pouch Disorders: A Multidisciplinary Approach for Diagnosis and Management provides much needed information on the evolution of pouch surgery, pouch surgery techniques, and surgery-associated complications, including inflammatory, functional, neoplastic, and metabolic complications. The book provides information on the anatomy of the pouch, pathogenesis of pouchitis and other pouch disorders, proper diagnostic modalities, and medical, endoscopic and surgical options for those disorders. The information has been compiled from a panel of national and international leading experts in the field, including basic scientists, gastrointestinal (GI) pathologists, GI radiologists, gastroenterologists, and more. - Features never-before-published information and technology from the vast experience of the contributors and editors in diagnosis and medical, endoscopic, and surgical management of pouchitis and other pouch disorders - Contains easy to access recommendations from experts - Provides access to an accompanying website with videos of endoscopic demonstrations of various configurations of the pouch, endoscopic evaluation of pouch disorders, and endoscopic treatment of pouch strictures, fistula, and anastomotic leaks/sinuses

Liver Elastography

Author : Sebastian Mueller
Publisher : Springer Nature
ISBN 13 : 3030405427
Total Pages : 711 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Liver Elastography by : Sebastian Mueller

Download or read book Liver Elastography written by Sebastian Mueller and published by Springer Nature. This book was released on 2020-06-02 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive book on the new elastographic techniques discussing the early assessment of liver fibrosis. The book covers all aspects of measuring liver stiffness starting from the methodology, the molecular basis of liver stiffness elevation up to current clinical algorithms and interpretation. Future directions and novel implications that go beyond diagnosis but are relevant for understanding of liver cirrhosis per se are also discussed in detail. Liver Elastography, is an essential companion for hepatologists and gastroenterologists that provides an overview of its basic principles and gives a detailed account of how to use elastrography in clinical practice.

Biochemistry of Pulmonary Emphysema

Author : C. Grassi
Publisher : Springer Science & Business Media
ISBN 13 : 144713771X
Total Pages : 205 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Biochemistry of Pulmonary Emphysema by : C. Grassi

Download or read book Biochemistry of Pulmonary Emphysema written by C. Grassi and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary emphysema is a disease which develops because of a localized imbalance between endogenous proteinase inhibitors and proteinases leaking from neurophils during phagocytosis at inflammatory foci within the lung. This volume not only reviews at a biochemical level what is known about the natural inhibitors and proteinases involved in connective tissue destruction within the lung, but also suggests novel methodologies for reestablishing proper enzyme-inhibitor balance, including the use of natural or synthetic inhibitors for supplementation or gene therapy.

Development of Sustainable Bioprocesses

Author : Elmar Heinzle
Publisher : John Wiley & Sons
ISBN 13 : 9780470058909
Total Pages : 316 pages
Book Rating : 4.0/5 (589 download)

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Book Synopsis Development of Sustainable Bioprocesses by : Elmar Heinzle

Download or read book Development of Sustainable Bioprocesses written by Elmar Heinzle and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioprocess technology involves the combination of living matter (whole organism or enzymes ) with nutrients under laboratory conditions to make a desired product within the pharmaceutical, food, cosmetics, biotechnology, fine chemicals and bulk chemicals sectors. Industry is under increasing pressure to develop new processes that are both environmentally friendly and cost-effective, and this can be achieved by taking a fresh look at process development; - namely by combining modern process modeling techniques with sustainability assessment methods. Development of Sustainable Bioprocesses: Modeling and Assessment describes methodologies and supporting case studies for the evolution and implementation of sustainable bioprocesses. Practical and industry-focused, the book begins with an introduction to the bioprocess industries and development procedures. Bioprocesses and bioproducts are then introduced, together with a description of the unit operations involved. Modeling procedures, a key feature of the book, are covered in chapter 3 prior to an overview of the key sustainability assessment methods in use (environmental, economic and societal). The second part of the book is devoted to case studies, which cover the development of bioprocesses in the pharmaceutical, food, fine chemicals, cosmetics and bulk chemicals industries. Some selected case studies include: citric acid, biopolymers, antibiotics, biopharmaceuticals. Supplementary material provides hands-on materials so that the techniques can be put into practice. These materials include a demo version of SuperPro Designer software (used in process engineering) and models of all featured case studies, excel sheets of assessment methods, Monte Carlo simulations and exercises. Previously available on CD-ROM, the supplementary material can now be accessed via http://booksupport.wiley.com by entering the author name, book title or isbn and clicking on the desired entry. This will then give a listing of all the content available for download. Please read any text files before downloading material.

How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Understanding Alpha-1 Antitrypsin Deficiency

Author :
Publisher :
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Understanding Alpha-1 Antitrypsin Deficiency by :

Download or read book Understanding Alpha-1 Antitrypsin Deficiency written by and published by . This book was released on 1994 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Alpha-1 COPD Love Story

Author : Sally Everett
Publisher :
ISBN 13 : 9781937650025
Total Pages : 200 pages
Book Rating : 4.6/5 (5 download)

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Book Synopsis An Alpha-1 COPD Love Story by : Sally Everett

Download or read book An Alpha-1 COPD Love Story written by Sally Everett and published by . This book was released on 2011 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sally Everett was about to turn fifty. A single parent and successful lawyer, she was, seemingly, a picture of health. She ate right, she didn't smoke, she was almost never sick, and she exercised regularly. Then a simple cold turned into pneumonia. She was hospitalized and x-rays were taken of her lungs. Subsequent blood tests clinched the diagnosis. Sally had chronic obstructive pulmonary disease (COPD) caused by Alpha-1, a genetic abnormality more common than cystic fibrosis. Her prognosis was, at best, ten years. At first Sally decided she could and would face this alone. Her subsequent struggles, candidly recounted here, are an invaluable resource for anyone with Alpha-1, COPD, or any chronic disease for that matter. Always careful to point out that your experience may not replicate hers, Sally walks you through her initial reaction to her diagnoses; learning how to cope; the role of exercise, oxygen and other therapies; genetic testing; clinical trials; facing depression and disability; and even end of life planning --