Alcohol, Immunity, and Cancer

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Author :
Publisher : CRC Press
ISBN 13 : 9780849357619
Total Pages : 322 pages
Book Rating : 4.3/5 (576 download)

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Book Synopsis Alcohol, Immunity, and Cancer by : Raz Yirmiya

Download or read book Alcohol, Immunity, and Cancer written by Raz Yirmiya and published by CRC Press. This book was released on 1992-11-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic alcoholism afflicts approximately 7% of the adult population of the United States and an even larger proportion in some other countries. Among the most devastating health problems associated with alcoholism are increased morbidity and mortality from infections and cancer. Alcohol, Immunity, and Cancer is the first book devoted entirely to presenting up-to-date comprehensive reviews on how the deleterious effects of alcohol consumption impact the immune system and increase the risk of developing many types of cancer. Topics covered include the effects of alcohol on cytokine activity, the modulation of natural killer cell activity by alcohol, fetal alcohol exposure and immunity, alcohol and hepatic carcinogenesis, and alcohol and cancer of the pancreas. Alcohol, Immunity, and Cancer will be invaluable for immunologists, pathologists, toxicologists, microbiologists, biochemists, endocrinologists, and neuroscientists interested in alcohol research. It will also benefit medical experts and general practitioners who need to know the role alcohol may play in the health and disease of their patients.

Alcohol and Cancer

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Author :
Publisher : Springer
ISBN 13 : 3319987887
Total Pages : 274 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Alcohol and Cancer by : Vasilis Vasiliou

Download or read book Alcohol and Cancer written by Vasilis Vasiliou and published by Springer. This book was released on 2018-10-26 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the Third Alcohol and Cancer Conference, this volume compiles the most up-to-date research on the role of alcohol consumption in carcinogenesis, from epidemiology to pathology metabolism and stem cells. More specifically, it delves into the effects of alcohol consumption and thyroid cancer, CD133+ progenitor cells, carcinogenic iron accumulation, developmental morphogens, and cancer-inducing epigenetic changes. Alcohol and Cancer: Proceedings of the Third International Conference is a timely update to Biological Basis of Alcohol-Induced Cancer, which followed the Second Alcohol and Cancer Conference, compiling cutting-edge research from graduate students, young scientists, and researchers. It is ideal for graduate students and researchers in oncology, hepatology, epigenetics, and alcohol consumption.

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

The Health Effects of Cannabis and Cannabinoids

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Publisher : National Academies Press
ISBN 13 : 0309453070
Total Pages : 487 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Health Effects of Cannabis and Cannabinoids by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Health Effects of Cannabis and Cannabinoids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-03-31 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

The Genetics of Alcoholism

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Author :
Publisher : Alcohol and Alcoholism
ISBN 13 : 9780195088779
Total Pages : 420 pages
Book Rating : 4.0/5 (887 download)

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Book Synopsis The Genetics of Alcoholism by : Henri Begleiter

Download or read book The Genetics of Alcoholism written by Henri Begleiter and published by Alcohol and Alcoholism. This book was released on 1995 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspective and details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in the development and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic view of the knowledge available on the hereditary influences of alcoholism.

Human Oral Mucosa

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Publisher : John Wiley & Sons
ISBN 13 : 0470959738
Total Pages : 151 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Human Oral Mucosa by : Christopher Squier

Download or read book Human Oral Mucosa written by Christopher Squier and published by John Wiley & Sons. This book was released on 2010-12-29 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Oral Mucosa: Development, Structure and Function is a new text that reflects the considerable increase in knowledge of oral mucosa that has occurred in recent years. Our understanding of the structure of oral mucosa is now established at a molecular rather than a tissue or cellular level. This in turn has revealed a level of function that was previously not suspected, including a sophisticated barrier to the penetration of exogenous materials, and the synthesis of specific antimicrobial compounds, representing components of the innate immune system. There is also a growing realization of commonality in structure and function between regions of oral mucosa and the mucosae of the esophagus and vagina. The aim of the present volume is to provide a more sophisticated text on human oral mucosa than presently exists in textbooks and to bring together information that is otherwise to be found in separate, specialist volumes into a comprehensive text. It relates structure at the molecular, cellular and tissue level to function and to clinical behavior. The volume is directed to advanced students and researchers in oral biology, as well as those in allied areas of investigation, such as dermatology, gynecology, internal medicine and pathology.

A Review of Human Carcinogens

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (815 download)

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Book Synopsis A Review of Human Carcinogens by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference

Download or read book A Review of Human Carcinogens written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diet and Health

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Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Diet and Health by : National Research Council

Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Immunological Surveillance

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Author :
Publisher : Elsevier
ISBN 13 : 1483159221
Total Pages : 289 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Immunological Surveillance by : Macfarlane Burnet

Download or read book Immunological Surveillance written by Macfarlane Burnet and published by Elsevier. This book was released on 2014-05-17 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunological Surveillance

Herbal Medicine

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Publisher : CRC Press
ISBN 13 : 1439807167
Total Pages : 500 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Herbal Medicine by : Iris F. F. Benzie

Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Alcohol in the European Union

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Author :
Publisher : Emro Publication
ISBN 13 : 9789289002646
Total Pages : 0 pages
Book Rating : 4.0/5 (26 download)

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Book Synopsis Alcohol in the European Union by : Peter Anderson

Download or read book Alcohol in the European Union written by Peter Anderson and published by Emro Publication. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: At head of title: World Health Organization, regional office for Europe.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

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Publisher : Academic Press
ISBN 13 : 0128094273
Total Pages : 431 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by : M. A. Hayat

Download or read book Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging written by M. A. Hayat and published by Academic Press. This book was released on 2016-12-28 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. - Presents the most advanced information regarding the role of the autophagic system in life and death - Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both - Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation - Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment - Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available

SITC’s Guide to Managing Immunotherapy Toxicity

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Publisher : Springer Publishing Company
ISBN 13 : 0826172156
Total Pages : 275 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis SITC’s Guide to Managing Immunotherapy Toxicity by : Marc S. Ernstoff, MD

Download or read book SITC’s Guide to Managing Immunotherapy Toxicity written by Marc S. Ernstoff, MD and published by Springer Publishing Company. This book was released on 2019-03-15 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Society for Immunotherapy of Cancer's handbook,SITC’s Guide to Managing Immunotherapy Toxicity, is a practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Separated into two parts, Part I contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with anti-CTLA4 agents, anti-PD1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is structured by common and uncommon toxicities that affect major organ sites throughout the body. It begins with a general summary of principles and management options followed by chapters focusing on specific toxicities such as rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, and ocular toxicities. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects with detailed summary tables for quick reference. Part II concludes with chapters covering management of special patient populations, including patients with autoimmune disease and geriatric patients, treatment and management of fatigue, and a final chapter dedicated to cost effectiveness and the toll of financial toxicity on patients and caregivers. With chapters written by world-recognized leaders in the immuno-oncology field, this text provides thorough coverage of the toxicity and management of adverse effects for immune checkpoint inhibitors. It is an indispensable resource for clinical oncologists, emergency physicians, hospitalists and other medical practitioners in both the hospital and community clinic settings, especially as the use of immune checkpoint inhibitors becomes a fixture in oncology care. Key Features: Outlines strategies for treating high-risk patients facing an acute or chronic side effect to immunotherapy Provides numerous tables that condense and highlight pertinent information for quick reference Describes the various clinical presentations and toxic reactions caused by immunotherapy Purchase includes access to the eBook for use on most mobile devices or computer

Multi-Drug Resistance in Cancer

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Publisher : Humana Press
ISBN 13 : 9781617796647
Total Pages : 492 pages
Book Rating : 4.7/5 (966 download)

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Book Synopsis Multi-Drug Resistance in Cancer by : Jun Zhou

Download or read book Multi-Drug Resistance in Cancer written by Jun Zhou and published by Humana Press. This book was released on 2012-08-09 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .

Alcohol and Cancer

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Publisher : CRC Press
ISBN 13 : 9780849379383
Total Pages : 296 pages
Book Rating : 4.3/5 (793 download)

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Book Synopsis Alcohol and Cancer by : Ronald R. Watson

Download or read book Alcohol and Cancer written by Ronald R. Watson and published by CRC Press. This book was released on 1992-05-22 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol clearly plays key roles in the promotion of cancers initiated by carcinogens. Thus, it is a major cause or significant contributing factor to many cancers. Ethanol affects the metabolism of anticancer drugs. It significantly contributes to viral hepatitis and liver cancer. In addition it modulates colorectal carcinogenesis, procarcinogen activation and risk of oral cancers. The mechanisms of ethanol's actions in carcinogen activation, and alcohol-related cancers are extensively reviewed. This book is designed for the researcher trying to understand how alcohol causes cancer, as well as the clinician/epidemiologist wishing to know more about its role in human cancer incidence.

Healed

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Publisher : Ebury Press
ISBN 13 : 9780143457206
Total Pages : 240 pages
Book Rating : 4.4/5 (572 download)

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Book Synopsis Healed by : Manisha Koirala

Download or read book Healed written by Manisha Koirala and published by Ebury Press. This book was released on 2022-03-15 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healed is the powerful, moving and deeply personal story of actor Manisha Koirala's battle against ovarian cancer. From her treatment in the US and the wonderful care provided by the oncologists there to how she rebuilt her life once she returned home, the book takes us on an emotional rollercoaster ride through her many fears and struggles, and shows how she eventually came out triumphant. Today, as she completes six years of being cancer-free, she shares her story-one marked by apprehensions, disappointments and uncertainties-and the lessons she learnt along the way. Through her journey, she unravels cancer for us and inspires us to not buckle under its fear, but emerge alive, kicking and victorious.

Biological Basis of Alcohol-Induced Cancer

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Author :
Publisher : Springer
ISBN 13 : 3319096141
Total Pages : 445 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Biological Basis of Alcohol-Induced Cancer by : Vasilis Vasiliou

Download or read book Biological Basis of Alcohol-Induced Cancer written by Vasilis Vasiliou and published by Springer. This book was released on 2014-11-26 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the recent years, a significant amount of research has emerged connecting the link between alcohol and cancer. The field has rapidly advanced, especially since the complex connection between alcohol and cancer has several unique sub areas that are being investigated. This proceedings volume will contain chapters based upon the presentation of the 2nd International Conference on Alcohol and Cancer in Colorado, 2013. The various topics explore the affects of alcohol on: liver and breast cancer; cell signaling and cancer; stem cells; biomarkers and metabolomics; aerodigestive cancers; cancer and the immune system and more.