Ag Nano Dendritic Three Dimensional 3d Surface Enhanced Raman Scattering Sers Substrate For In Situ Liquid Media Detection

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Ag Nano-dendritic Three-dimensional (3D) Surface-enhanced Raman Scattering (SERS) Substrate for In-situ Liquid Media Detection

Author : Milind Mansing Pawar
Publisher :
ISBN 13 :
Total Pages : 81 pages
Book Rating : 4.:/5 (132 download)

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Book Synopsis Ag Nano-dendritic Three-dimensional (3D) Surface-enhanced Raman Scattering (SERS) Substrate for In-situ Liquid Media Detection by : Milind Mansing Pawar

Download or read book Ag Nano-dendritic Three-dimensional (3D) Surface-enhanced Raman Scattering (SERS) Substrate for In-situ Liquid Media Detection written by Milind Mansing Pawar and published by . This book was released on 2019 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous monitoring of certain environmental pollutants, biological species, chemical species, and explosives are of utmost importance in recent times. Surface-enhanced Raman scattering (SERS) provides most promising option as it is a highly sensitive technique which allows for ultrasensitive detection of molecules and provides excellent structural information. To obtain rich results through Surface-enhanced Raman scattering, proper design of enhancing substrate plays vital role. Contemporary SERS substrates don't provide ease to detect liquid analytes for in-situ spectroscopy. Liquid media detection through SERS relies on highly statistical binding of analytes to SERS-sensitive hot spots. Moreover, it becomes extremely difficult to detect flowing liquid media in-situ with two dimensional substrates as very small volume of Liquid contact with substrates. Single crystal Ag dendrite structures possess high surface area along with narrow gaps and sharp edges. Compared with other nanostructures, the hierarchical nanostructures-dendritic Ag, consisting of multi-level branches can significantly promote the SERS enhancement and serve as effective SERS substrates with high sensitivity and reproducibility. Such complex nanostructures may provide a large amount of "hot spots" at the end of branches or the junctions of adjacent Ag branches. In addition, the large surface area of Ag dendrites can enhance the interaction between analytes and sensing substrates. Ag dendrites can easily be produced, by use of one of the simplest galvanic reactions, the reaction of AgNO3 with Cu. We have developed novel yet simple Surface-enhanced Raman scattering- active substrate having three-dimensional array of Ag-dendrites grown within square geometry capillary tube of borosilicate glass via such galvanic replacement reaction with inserted copper wire. Systematic study of growth mechanism of Ag-dendrites was carried out and complex nature of seemingly "simple" galvanic replacement reaction has been proposed. The resultant Ag dendrites were characterized by scanning electron microscopy, transmission electron microscopy, energy dispersive spectroscopy and X-ray diffraction. Atime-dependent investigation on the growth mechanism of the Ag dendrites revealed that they develop through a particle-mediated growth process. The effect of the reactant concentrations on the morphology of the synthesized Ag dendrites was also studied. This study on Ag dendrite growth mechanisms are not only scientifically intriguing, but also technologically important. Novel Ag dendrite three-dimensional SERS substrate exhibits excellent sensitivity and a very good reproducibility. We have detected rhodamine 6G(R6G) with lowest concentration of 10-11 M in aqueous solution. These Ag dendrite nanostructured three-dimensional SERS substrates are proved as excellent in-situ liquid media Raman detection substrates due to availability of extensive hot spots. It has significant potential to be used as SERS substrates for fast and accurate detection of trace amount of organic contaminants in flowing liquid media.

Metal Nanodendrites and Their Applications as 3D Surface Enhanced Scattering (SERS) Substrates

Author : Aseem Athavale
Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.:/5 (132 download)

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Book Synopsis Metal Nanodendrites and Their Applications as 3D Surface Enhanced Scattering (SERS) Substrates by : Aseem Athavale

Download or read book Metal Nanodendrites and Their Applications as 3D Surface Enhanced Scattering (SERS) Substrates written by Aseem Athavale and published by . This book was released on 2021 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasensitive detection of chemicals and biological analytes has been a focus of a lot of studies in the recent years. In this search for the versatile detection technique, Surface Enhanced Raman Spectroscopy (SERS) has proved to be one powerful method. SERS is a powerful vibrational spectroscopy technique that allows for label free ultrasensitive detection. This method utilizes the Localized Surface Plasmonresonance (LSPR) effect of nanoparticles. LSPR effect is profound in noble metals such as silver (Ag) and gold (Au). We have developed a novel SERS substrate using Ag dendrites that can be applied as a ready to-use device in a variety of applications.The substrate was fabricated via self-deposition of silver nanodendrites on copper wires of 80 microns inside different channels of glass or silver coated PDMS. The deposition was done by the galvanic replacement reaction between silver nitrate and copper. This reaction was previously thought as the simple high-school chemistry reaction, i.e. formation of Ag dendrites can be explained by a simple reaction mechanism as follows :. a reduction reaction, Ag+ + e− Ag, takes place only on a metal surface, first on Cu and then on newly formed Ag. The electron comes from the oxidation reaction Cu Cu2+ 2e−,which takes place at Cu surface, where Cu2+ is released into the solution, and electron transport inside the metal-to-metal surface to reduce Ag+. The reduction rate is higher on the Ag (1 1 1) surface, leading to preferential growth in the [1 1 1] direction. However, a series of experiments revealed that this reaction mechanism is much more complex than a simple two step galvanic replacement reaction: metal Ag could 5 form through reduction of Ag+ by intermediate nitrite (N?2−) ions inside the solution on a surface away from Cu. It was also found that Ag dendrites developed through a particle-mediated growth process. This new reaction mechanism can be utilized to generate completely freestanding, pure, and clean single crystal Ag dendrites at room temperature within a few minutes.After a series of studies on morphology and reaction conditions, we developed a robust 3-D SERS substrate using Ag dendrites, which has extremely high sensitivity and excellent reproducibility. More importantly,such device can detect molecules in-liquid without sampling and drying. The sensitivity of the substrate was verified with rhodamine 6G (R6G) with the lowest concentration of about 1 x 10-14 M. We also experimented with other common SERS molecules like Methylene Blue and 4-Methoxybenzoic Acid and were able to detect them as well at very low concentration.For better understanding of the mechanism behind such high sensitivity, we conducted FDTD simulations on representative 2D/3D models of dendrites according to the SEM images. These simulations revealed a high electric field enhancement of 106 - 107 from narrow gaps between branches in the dendrite structure.Aiming for practical application of the device, we developed a method of calibrating these devices using low concentrations of R6G. After calibration, we were able to reliably detect low concentrations of around 0.5 ppm of Thiabendazole (TBZ), which is a commonly used pesticide has been labelled as a potential carcinogen. These 3-D SERS substrates were proved as a precise and fast in-situ Raman detection method for flowing liquid media.

Silver Dendrite Based Three-dimensional Surface Enhanced Raman Scattering (SERS) Substrates

Author : Sandesh Rajkumar Shelke
Publisher :
ISBN 13 :
Total Pages : 77 pages
Book Rating : 4.:/5 (973 download)

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Book Synopsis Silver Dendrite Based Three-dimensional Surface Enhanced Raman Scattering (SERS) Substrates by : Sandesh Rajkumar Shelke

Download or read book Silver Dendrite Based Three-dimensional Surface Enhanced Raman Scattering (SERS) Substrates written by Sandesh Rajkumar Shelke and published by . This book was released on 2016 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three-dimensional (3D) hierarchical nanostructures have been considered as one of the most promising surface-enhanced Raman spectroscopy (SERS) substrates because it provides high-density hotspots along the three-dimension directions and high surface areas. In this thesis, we report the synthesis process to develop 3D SERS substrates in thin wall quartz capillary tube on Cu wire. These 3D SERS substrates consist of Ag dendrite, Au-Ag and Pd-Ag bimetallic nanostructures which was synthesized by employing simple galvanic replacement reactions (GRR). In this synthesis process Cu wire which is used as substrate was inserted in the thin walled quartz capillary tube and then AgNO3 was injected into the tube to form Ag dendrite on the Cu wire substrate. This pre-prepared dendrite was used to prepare bimetallic nanostructures of Au-Ag and Pd-Ag by injecting chlorauric acid (HAuCl4) and palladium chloride (PdCl4) into the tube, respectively. The GRR process leads to the replacement of Ag atoms by Au and Pd which causes corresponding morphological change of the underlying Ag dendrite. The GRR leaves pores where Ag is depleted. The morphological and compositional changes caused by GRR was analyzed by using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Two close metallic surfaces can enhance the electromagnetic (EM) field around molecules absorbed between them, which leads to extremely high SERS enhancement. These 3D SERS substrates was tested in detection of aqueous 4-Mercaptobenzoic Acid (4-MBA) solution with various concentrations. The fabricated substrate was employed to detect the 4-MBA solution to the detection limit down to 10-13 M and exhibits highenhanced performance. The results indicated that these 3D unique bimetallic nanostructures can amplify Raman signals for extremely low concentration molecules as compared to the Ag dendrite nanostructure substrates.

A 3D SERS Device for Highly Sensitive Detection of Organic Chemicals in Liquid

Author : Sankgeeth Vennila Sigamani
Publisher :
ISBN 13 :
Total Pages : 84 pages
Book Rating : 4.:/5 (132 download)

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Book Synopsis A 3D SERS Device for Highly Sensitive Detection of Organic Chemicals in Liquid by : Sankgeeth Vennila Sigamani

Download or read book A 3D SERS Device for Highly Sensitive Detection of Organic Chemicals in Liquid written by Sankgeeth Vennila Sigamani and published by . This book was released on 2021 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detection of organic chemicals in liquid medium have been gaining utmost attention in recent times. Real time detection and monitoring of a variety of environmental pollutants, explosive materials, chemical agents,and pharmaceutical drugs in liquid medium are of great need in today's technological advancements. While there are several scattering, emission and spectroscopy techniques in use, Raman spectroscopy is attractive because of its molecular specificity i.e., each molecule has a Raman fingerprint. Raman spectroscopy utilizes the inelastic portion of the scattered wave for detection. But since intensity of inelastic scattering (Raman scattering) is very low, compared to the elastic scattering, low concentration analysis has been challenging. Surface-Enhanced Raman spectroscopy or Surface-Enhanced Raman Scattering (SERS) potentially overcomes this challenge, with its good detection capabilities for lower concentrations in liquid solution. SERS enhances the Raman signal of molecules (capable of 1010-fold enhancement) when they are adsorbed on a metal nanostructure (termed as SERS substrate) surface. The design of SERS substrate plays a crucial part in the enhancement of the Raman signal. Conventional 2D substrates are not very efficient in providing binding of the analyte molecules to SERS sensitive hotspots and in-situ detection can be challenging, owing to the low volume of liquid on the surface. These challenges can be overcome by using three-dimensional (3D) hierarchical nanostructures as SERS substrates, because of its high hotspot density along all spatial directions.Single crystal 3D silver dendrites are desirable for such application,due to the presence of nanotips and nanogaps which act as hotspots enhancing the Raman signal. These silver nano dendrites can be generated by a simple Galvanic Replacement Reaction (GRR) between copper wire and silver nitrate solution, yielding a multi-level branched nanostructure. These branched surfaces in proximity, have the capability to enhance the Raman signal of the analyte present, due to Localized Surface Plasmon Resonance effect (LSPR).In this thesis, a reliable, reusable and low-cost SERS device,employing 3D silver nano dendrites, that can be used for in-situ monitoring of organic molecules in liquid flows is presented. This device has the capability to detect very low concentrations of organic chemicals, at parts per million range in liquid in real time, without much of an erroneous measurement and sample preparation. The device was made of 3D silver nano-dendrites enclosed in channels in PDMS. It is reusable, with good reproducibility and has the potential for multichannel configurations that can provide parallel analysis. This device is made reliable by calibrating using Rhodamine-6g, as a reference molecule. It can be then used to detect various Raman active molecules in liquid solution with varying concentrations. We detected molecules of 4-Mercaptobenzoic Acid (4- MBA) and Methylene blue in liquid solutions with very low concentrations. Detection of Acetaminophen and Thiabendazole with good reproducibility, makes the device to have significant potentials at real-world applications in different fields. The device was successful in detecting ultra-low concentrations with high sensitivity, as compared to previously reported nano substrates thus making it a significant SERS substrate.

Engineering Noble-metal Nanoparticles for Sensing and Imaging with Surface-enhanced Raman Scattering

Author : Matthew Rycenga
Publisher :
ISBN 13 :
Total Pages : 160 pages
Book Rating : 4.:/5 (758 download)

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Book Synopsis Engineering Noble-metal Nanoparticles for Sensing and Imaging with Surface-enhanced Raman Scattering by : Matthew Rycenga

Download or read book Engineering Noble-metal Nanoparticles for Sensing and Imaging with Surface-enhanced Raman Scattering written by Matthew Rycenga and published by . This book was released on 2011 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research investigated the surface-enhanced Raman scattering (SERS) from Ag and Au nanoparticles with an aim to better understand the SERS mechanism and to implement this technique for single-molecule detection and imaging. In addition, SERS was used as a sensitive probe to study molecules confined to a nanoparticle's surface. The first part of this work focused on measuring the SERS from different Ag and Au nanoparticles and determining how their structural and physical properties affect SERS. The effects of shape, size, and Au-Ag composition on SERS are determined using Ag nanocubes, Ag nanospheres, and Au-based nanocages. I also demonstrate several techniques used to study the SERS of single nanoparticles, one at a time, which has provided significant insight into the SERS effect. I then discuss the development of a new and simple way to create large SERS enhancements by taking advantage of the supporting substrate of a nanoparticle. In this technique, simply depositing a single Ag nanocube on a metal substrate can increase its SERS enhancements to levels capable of single-molecule detection. In the second part of this work I used SERS as a molecular probe to understand how glucose molecules interact at a nanocube's surface, and as an optical thermometer to quantify the temperature change at the surface of a Au-based nanocage during the photothermal effect. The nanoparticles were coated with highly ordered self-assembled monolayers (SAMs), and then SERS was used to determine the structural and conformational changes in the SAMs as a result of perturbations from the environment. This allowed me to use SERS to directly probe the molecules on the nanoparticle's surface. In the final part of this work, I used nanocubes and nanospheres in SERS imaging. The resolution, sensitivity, and penetration depth are determined for our Raman microprobe system. In addition, phantoms are used to generate SERS images of three-dimensional microstructures.

Surface-Enhanced Raman Scattering

Author : Zhong-Qun Tian
Publisher : John Wiley & Sons Incorporated
ISBN 13 : 9780470068083
Total Pages : 400 pages
Book Rating : 4.0/5 (68 download)

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Book Synopsis Surface-Enhanced Raman Scattering by : Zhong-Qun Tian

Download or read book Surface-Enhanced Raman Scattering written by Zhong-Qun Tian and published by John Wiley & Sons Incorporated. This book was released on 2010-06-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-Enhanced Raman Spectroscopy: Principles, Experiments, and Applications is a comprehensive, up to date, and balanced treatment of the theoretical and practical aspects of Surface-Enhanced Raman Scattering (SERS), a useful branch of spectroscopy for several areas of science. This book describes the basic principles of SERS, including SERS mechanisms, performing SERS measurements, and interpreting data. Also emphasized are applications in electrochemistry; catalysis; surface processing and corrosion; Self-Assemble-Layer and L-B Films; polymer science; biology; medicine and drug analysis; sensors; fuel cells; forensics; and archaeology. It is an essential guide for student and professional analytical chemists.

Frontiers of Surface-Enhanced Raman Scattering

Author : Yukihiro Ozaki
Publisher : John Wiley & Sons
ISBN 13 : 111870357X
Total Pages : 466 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Frontiers of Surface-Enhanced Raman Scattering by : Yukihiro Ozaki

Download or read book Frontiers of Surface-Enhanced Raman Scattering written by Yukihiro Ozaki and published by John Wiley & Sons. This book was released on 2014-02-19 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of Surface-Enhanced Raman Scattering (SERS) theory, substrate fabrication, applications of SERS to biosystems, chemical analysis, sensing and fundamental innovation through experimentation. Written by internationally recognized editors and contributors. Relevant to all those within the scientific community dealing with Raman Spectroscopy, i.e. physicists, chemists, biologists, material scientists, physicians and biomedical scientists. SERS applications are widely expanding and the technology is now used in the field of nanotechnologies, applications to biosystems, nonosensors, nanoimaging and nanoscience.

Surface Enhanced Raman Scattering: New Theoretical Approaches, Materials and Strategies

Author : Ivano Alessandri
Publisher : Frontiers Media SA
ISBN 13 : 2889635538
Total Pages : 175 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Surface Enhanced Raman Scattering: New Theoretical Approaches, Materials and Strategies by : Ivano Alessandri

Download or read book Surface Enhanced Raman Scattering: New Theoretical Approaches, Materials and Strategies written by Ivano Alessandri and published by Frontiers Media SA. This book was released on 2020-03-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ultrasensitive Surface Enhanced Raman Scattering Nanomotors

Author : Xiaobin Xu (Ph. D.)
Publisher :
ISBN 13 :
Total Pages : 230 pages
Book Rating : 4.:/5 (982 download)

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Book Synopsis Ultrasensitive Surface Enhanced Raman Scattering Nanomotors by : Xiaobin Xu (Ph. D.)

Download or read book Ultrasensitive Surface Enhanced Raman Scattering Nanomotors written by Xiaobin Xu (Ph. D.) and published by . This book was released on 2014 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Localized surface plasmon resonance resulting from the concerted oscillations of conduction-band electrons in noble-metal (Au, Ag) nanostructures greatly induces enhanced electric ([italic E]) fields in confined nanoscale locations, such as on the tips of nanorods or in the junctions of nanodimers. These [italic E]-field enhanced locations are called hot spots. In the vicinity of hot spots, Raman scattering spectra of biochemicals can be substantially amplified with an [italic E]4 dependence due to the [italic E]-field enhancement of both the incident light and Raman spectra. This is called surface enhanced Raman scattering (SERS). SERS is known for its high sensitivity in providing fingerprint vibrational information of molecules. It has triggered intense interest because of its potential applications for label-free and multiplex biochemical detection relevant to medical, environmental and defense purposes. However, the tremendous potential of SERS for ultrasensitive detection has still not materialized because of four major obstacles: (1) it is extremely difficult to obtain a large number of hotspots for sensitive and reproducible detection due to the stringent requirement of hot spots of only a few nanometers; (2) it is arduous to achieve ultrasensitivity for the detection of a single/few molecules; (3) it is challenging to assemble the hot-spots at designated positions for location predicable sensing; and (4) it is even more difficult to change the state-of-the-art static/passive sensing schemes into dynamic/robotized schemes and also to incorporate multi-functionality into a single SERS nanostructure. In this research, we addressed the aforementioned problems by rational design, fabrication and robotization of ultrasensitive SERS nanomotor sensors. A nanomotor sensor consists of a tri-layer structure with a three-segment Ag/Ni/Ag nanorod as the core, a thin layer of silica in the center, and uniformly distributed Ag nanoparticles as the outer layer. The inner metallic nanorod core is the key structure in realizing the concept of the robotization of nanosensors, which can be electrically polarized and thus efficiently manipulated by electric tweezers. The presence of the Ni segment in the metallic nanowire core also allows manipulation and assembling by magnetic interactions. The central silica layer provides a supporting substrate for the synthesis of the Ag nanoparticles and separates the Ag nanoparticles from the metallic nanorod core to eliminate the effect of plasmonic quenching. Finally, the outermost layer made of Ag nanoparticles with optimized sizes and junctions provides a large number of hot spots (~1200/ [mu] m2) for ultrasensitive SERS detection with single molecule sensitivity and an enhancement factor (EF) of 1.1×1010. Moreover, two additional SERS enhancement mechanisms were investigated, i.e., the optical management with nanophotonic devices and the near field effect, which can readily increase the EF by 10 and 2 times, respectively, to at least 1011. Finally, three applications of the SERS nanomotor sensors have been demonstrated: (1) the ultrasensitive SERS nanomotors were transported and assembled into a 3×3 array for location predicable sensing of multiplex molecules; (2) ultrasensitive SERS nanomotors were transported to individual living cells amidst many cells for single-cell bioanalysis; and (3) the SERS nanomotor sensors can be controlled to rotate by the electric tweezers for tunable biochemical release and detection. This research, exploring robotized nanosensors by integrating SERS and NEMS, is innovative in both material design and device concept, which could inspire a new device scheme for various bio-relevant applications.

Surface Enhanced Raman Spectroscopy for Biophysical Applications

Author : Claudia Fasolato
Publisher : Springer
ISBN 13 : 3030035565
Total Pages : 167 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Surface Enhanced Raman Spectroscopy for Biophysical Applications by : Claudia Fasolato

Download or read book Surface Enhanced Raman Spectroscopy for Biophysical Applications written by Claudia Fasolato and published by Springer. This book was released on 2018-12-05 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the mechanisms affecting the spectroscopic response of SERS-active systems for effective applications. SERS spectroscopy is an ultrasensitive analytical technique with great potential for applications in the field of biophysics and nanomedicine. As examples, the author presents the design of nanocolloid-based SERS-active substrates for molecular sensing and of a folate-based SERS-active nanosensor capable of selectively interacting with cancer cells, enabling cancer diagnostics and therapy at the single-cell level. The author also suggests novel paths for the systematization of the SERS nanosystem design and experimental protocols to maximize sensitivity and reproducibility, which is essential when real-world biomedical applications are the goal of the study. With a combined approach, both fundamental and applied, and a detailed analysis of the state of the art, this book provides a valuable overview both for students new to SERS spectroscopy and for experts in the field.

Highly Efficient Surface Enhanced Raman Scattering (SERS) Nanowire/Ag Composites

Author :
Publisher :
ISBN 13 :
Total Pages : 4 pages
Book Rating : 4.:/5 (64 download)

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Book Synopsis Highly Efficient Surface Enhanced Raman Scattering (SERS) Nanowire/Ag Composites by :

Download or read book Highly Efficient Surface Enhanced Raman Scattering (SERS) Nanowire/Ag Composites written by and published by . This book was released on 2007 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optically based sensing provides advantages over electronic sensing because optical spectra can uniquely fingerprint a chemical compound, significantly reducing false alarms and simplifying the detection process. In addition, light can easily be directed over long distances, enabling remote sensing. One of the most promising optical sensing techniques is surface enhanced Raman scattering (SERS). In Raman scattering (RS) of light from a chemical of interest, the vibrational modes in the chemical redshift the frequency of the scattered light, producing a spectrum characteristic of that molecule. Ordinary Raman scattering cross-sections are very small, resulting in low sensitivity (1E-8 of the intensity of the exciting laser); this is not a problem for most solids and liquids, because of the large numbers of molecules or atoms exposed to the laser light, but in the case of trace amounts of molecules in gases or liquids, detection through ordinary Raman scattering is virtually impossible. However, SERS enhances the Raman signal by many orders of magnitude by the use of a substrate of metal nanoparticles. The SERS enhancement of molecules adsorbed on the roughened metal surface is caused by local electromagnetic fields that are created by the laser excitation of surface plasmons at the metal surface. Even larger SERS effects can be produced by local "hot spots" in the electric fields, produced by interactions of localized plasmons on adjacent or neighboring nanoparticles. Although the SERS effect has been recognized for a long time, a full understanding of the phenomenon has not yet been achieved. This lack of understanding limits its application potential, as it is difficult to produce highly sensitive, inexpensive, and repeatable SERS substrates. To address these issues, we have developed a new SERS substrate material consisting of dielectric/Ag metal shell nanowires that exhibit high SERS sensitivity due to their plasmonic coupling.

Surface Enhanced Raman Spectroscopy (SERS) Using Three-Dimensional DNA-Nanoparticle Nanostructures

Author : 蘇泰維
Publisher :
ISBN 13 :
Total Pages : 42 pages
Book Rating : 4.:/5 (899 download)

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Book Synopsis Surface Enhanced Raman Spectroscopy (SERS) Using Three-Dimensional DNA-Nanoparticle Nanostructures by : 蘇泰維

Download or read book Surface Enhanced Raman Spectroscopy (SERS) Using Three-Dimensional DNA-Nanoparticle Nanostructures written by 蘇泰維 and published by . This book was released on 2014 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Surface-Enhanced Raman Spectroscopy

Author : Eric Le Ru
Publisher : Elsevier
ISBN 13 : 0080931553
Total Pages : 688 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Principles of Surface-Enhanced Raman Spectroscopy by : Eric Le Ru

Download or read book Principles of Surface-Enhanced Raman Spectroscopy written by Eric Le Ru and published by Elsevier. This book was released on 2008-11-17 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed. - Represents one of very few books fully dedicated to the topic of surface-enhanced Raman spectroscopy (SERS) - Gives a comprehensive summary of the underlying physical concepts around SERS - Provides a detailed analysis of plasmons and plasmonics

Advanced Substrate Design for Label-free Detection of Trace Organic and Biological Molecules

Author : Zachary Allen Combs
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (88 download)

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Book Synopsis Advanced Substrate Design for Label-free Detection of Trace Organic and Biological Molecules by : Zachary Allen Combs

Download or read book Advanced Substrate Design for Label-free Detection of Trace Organic and Biological Molecules written by Zachary Allen Combs and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: To truly realize and exploit the extremely powerful information given from surface-enhanced Raman scattering (SERS) spectroscopy, it is critical to develop an understanding of how to design highly sensitive and selective substrates, produce specific and label-free spectra of target analytes, and fabricate long-lasting and in-the-field ready platforms for trace detection applications. The study presented in this dissertation investigated the application of two- and three-dimensional substrates composed of highly-ordered metal nanostructures. These systems were designed to specifically detect target analytes that would enable the trace, label-free, and real-time detection of chemicals and biomolecules. Specifically, this work provides new insight into the required properties for maximizing electromagnetic and chemical Raman enhancement in three-dimensional porous alumina substrates by designing metal nanostructure shape, density, aggregated state, and most importantly aligning the substrate pore size with the excitation wavelength used for plasmonic enhancement leading to the ppb detection of vapor phase hazardous chemicals. A new micropatterned silver nanoparticle substrate fabricated via soft lithography with specific functionalization was developed, which allows the simultaneous analyte and background detection for trace concentrations of the target biomolecule, immunoglobulin G. Also, a novel functionalized SERS hot spot fabrication technique, which utilizes highly specific aptamers as both the mediator for electrostatic assembly of gold nanoframe dimers as well as the biorecognition element for the target, riboflavin, to properly locate the tethered biomolecule within the enhanced region for trace detection, was demonstrated. We suggest that the understanding of SERS phenomena that occur at the interface of nanostructures and target molecules combined with the active functionalization and organization of metal nanostructures and trace detection of analytes discussed in this study can provide important insight for addressing some of the challenges facing the field of SERS sensor design such as high sensitivity and selectivity, reliable and repeatable label-free identification of spectral peaks, and the well-controlled assembly of functional metal nanostructures. This research will have a direct impact on the future application of SERS sensors for the trace detection of target species in chemical, environmental, and biomedical fields through the development of specific design criteria and fabrication processes.

Dry and Wet Surface Enhanced Raman Scattering Substrates

Author : Ahmed Mahmoud
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)

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Book Synopsis Dry and Wet Surface Enhanced Raman Scattering Substrates by : Ahmed Mahmoud

Download or read book Dry and Wet Surface Enhanced Raman Scattering Substrates written by Ahmed Mahmoud and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few decades, surface enhanced Raman scattering (SERS) has been evolving as a powerful analytical technique for the detection of a wide of chemical and biological molecules. The technique can reach a sensitivity of single molecule detection, which triggered plenty of ongoing research. In addition, technological advancements in photonics and nanoscience have resulted in the advent of portable and handheld Raman systems. These devices help SERS analysis move from expensive heavy-equipped research labs to low cost field deployable-research. The development of efficient SERS substrates that can provide signal enhancement by many orders of magnitude is a core component for SERS. The SERS substrates market and research are generally dominated by rigid solid substrates that are fabricated mostly by micro/nanofabrication techniques. Although these methods can provide reproducible substrates, they suffer from usability constraints because of their high cost of fabrication. The work presented in this thesis explored cost-effective approaches to develop and optimize SERS substrates. The substrates investigated are divided into two main categories, membrane-based SERS substrates and in-solution SERS substrates. The membrane-based SERS substrates were fabricated by equipment-free methods. In these deviceless methods, gold and silver nanostructures were incorporated in-situ within the micropores of polyvinylidene fluoride (PVDF) membranes by seed mediated and seedless protocols, respectively. The SERS performance of these substrates was investigated and optimized by controlling the loading of plasmonic nanostructures. These flexible inexpensive substrates have the advantages of being easy to fabricate and to use. In addition, the variation in the SERS performance of these substrate was less than 20% within the same substrate and from substrate-to-substrate, which reflects acceptable reproducibility. Analytical applications of these substrates were demonstrated using a Raman microscope as well as a handheld Raman spectrometer. The second category of the SERS substrates studied was based on the optimization of gold nanostars and graphene-silver nanocomposites for water dispersible SERS measurements. In-solution SERS platforms are not used as commonly as solid-based substrates; however, these wet platforms can provide some advantages over the dried-based ones in terms of cost, reproducibility, and analysis time. The SERS performance of gold nanostars with different branch lengths was optimized based on the type of Good's buffer, the ratio of buffer to gold concentration, and their aggregation. Our results were counterintuitive in that the gold nanostars with the shorter branches provided the largest in-solution SERS intensity. These findings can be attributed to higher surface coverage of the Raman probe rather than enhanced electromagnetic effects. Graphene-silver nanocomposites were investigated also as in-solution SERS substrates with a large 2D surface area. The SERS behavior of these nanocomposites were studied using graphene, a thiolated Raman probe, and a dye labelled ssDNA to simulate different possible interactions. The SERS and plasmonic performance of these nanocomposites can be tuned by the size of silver nanoparticles on these substrates. The nanocomposites were more stable and showed superior SERS performance when compared to commercial silver nanoparticles. The contributions of this work can pave the way for flexible membrane-based and in-solution SERS substrates to be accompanied with a handheld Raman device for field-deployable SERS measurements.

Surface Enhanced Raman Spectroscopy

Author : Sebastian Schlücker
Publisher : John Wiley & Sons
ISBN 13 : 3527633065
Total Pages : 97 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Surface Enhanced Raman Spectroscopy by : Sebastian Schlücker

Download or read book Surface Enhanced Raman Spectroscopy written by Sebastian Schlücker and published by John Wiley & Sons. This book was released on 2011-09-19 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems. From the contents: * Theory and practice of SERS * Analytical applications * SERS combined with other analytical techniques * Biophysical applications * Life science applications including various microscopies Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.

SOLUTION PROCESSABLE SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) SUBSTRATE

Author : Narayan Sharma
Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.:/5 (929 download)

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Book Synopsis SOLUTION PROCESSABLE SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) SUBSTRATE by : Narayan Sharma

Download or read book SOLUTION PROCESSABLE SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) SUBSTRATE written by Narayan Sharma and published by . This book was released on 2015 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Enhanced Raman Spectroscopy is a powerful analytical tool to obtain information on molecular composition. This technique has advanced greatly since its discovery, allowing Raman spectroscopic analysis down to the detection of single molecule. The heart of SERS performance lies on the choice and fabrication of SERS substrate. The most investigated metals for SERS substrates are Au and Ag. Unfortunately, the fabrication of such devises poses a significant challenge due to an expensive deposition technology including, vapor deposition, electron-beam lithography, focused ion-beam lithography, and nano-transfer printing. Herein, we report a simple and low-cost solution processing method to fabricate SERS substrates. Au nanoparticles and Au/CdS core/shell nanoparticles were synthesized and their solutions deposited on glass plates in the form of nanoparticle films. Although the enhancement of Raman signal due to Ag nanoparticle substrates is greater than that of Au, the high stability and a wide variety of fabrication methods makes Au nanoparticles more favorable candidates for SERS substrates. The performance of the SERS substrates fabricated using this method was found to be comparable with the commercially available substrates.