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Advancing Science And Elimination Of The Use Of Laboratory Animals For The Development And Control Of Vaccines And Hormones
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Book Synopsis Advancing Science and Elimination of the Use of Laboratory Animals for the Development and Control of Vaccines and Hormones by : Fred Brown
Download or read book Advancing Science and Elimination of the Use of Laboratory Animals for the Development and Control of Vaccines and Hormones written by Fred Brown and published by S. Karger AG (Switzerland). This book was released on 2002 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation plays a major role in the development and control of biological products and large numbers of animals are used for routine batch control. During the past few years considerable attention has been paid to the concept of replacing, reducing and refining (the three Rs) the use of animals for this purpose. This volume contains the proceedings of an international meeting held in Utrecht in November 2001 in which the problems associated with applying the three Rs were discussed. Particular emphasis was given to the validation and regulatory acceptance of in vitro methods and new concepts of quality control. Those issues are important for the scientific community at large as well as manufacturers, regulatory authorities and everyone concerned with animal welfare.
Author :Rijksinstituut voor volksgezondheid en milieuhygiëne (Pays-Bas) Publisher : ISBN 13 :9783805575096 Total Pages :0 pages Book Rating :4.5/5 (75 download)
Book Synopsis Advancing Science and Elimination of the Use of Laboratory Animals for Development and Control of Vaccines and Hormones by : Rijksinstituut voor volksgezondheid en milieuhygiëne (Pays-Bas)
Download or read book Advancing Science and Elimination of the Use of Laboratory Animals for Development and Control of Vaccines and Hormones written by Rijksinstituut voor volksgezondheid en milieuhygiëne (Pays-Bas) and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advancing Science and Elimination of the Use of Laboratory Animals for the Development and Control of Vaccines and Hormones by : Fred Brown
Download or read book Advancing Science and Elimination of the Use of Laboratory Animals for the Development and Control of Vaccines and Hormones written by Fred Brown and published by S. Karger AG (Switzerland). This book was released on 2002 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation plays a major role in the development and control of biological products and large numbers of animals are used for routine batch control. During the past few years considerable attention has been paid to the concept of replacing, reducing and refining (the three Rs) the use of animals for this purpose. This volume contains the proceedings of an international meeting held in Utrecht in November 2001 in which the problems associated with applying the three Rs were discussed. Particular emphasis was given to the validation and regulatory acceptance of in vitro methods and new concepts of quality control. Those issues are important for the scientific community at large as well as manufacturers, regulatory authorities and everyone concerned with animal welfare.
Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council
Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Book Synopsis Why Animal Experimentation Matters by : Ellen Frankel Paul
Download or read book Why Animal Experimentation Matters written by Ellen Frankel Paul and published by Transaction Publishers. This book was released on with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation has made a crucial contribution to many of the most important advances in modern medicine. The development of vaccines for deadly viruses like rabies and yellow fever depended upon animal research, and much of our basic knowledge about human health and physiology was discovered through the use of animals as well. Inspite of these gains, animal rights activists have been zealous in communicating to the public and policymakers their view that the use of animals in medical research is morally wrong and should be severely curtailed or eliminated. The activists' arguments draw upon a range of disciplines and focus on both practical and ethical aspects of animal experimentation. Advocates of animal experimentation have been slow to respond to these arguments. Given that the worldwide toll of communicable diseases is still immense--and that deadly new pathogens may emerge at any time in the future to menace human health--failing to defend animal experimentation from the arguments of its opponents has disastrous implications. A quick response to an unanticipated threat on the order of the AIDS epidemic is unimaginable absent a vigorous research establishment, which in turn is dependent on animal proxies. Why Animal Experimentation Matters is a first attempt by research scientists and moral philosophers to mount a convincing defense against animal rights enthusiasts. Because opponents of animal experimentation come from a variety of intellectual backgrounds, this defense is necessarily interdisciplinary as well. In this collection of eight essays, the authors scrutinize how animal experimentation actually functions in the laboratory, the vital role that it plays in palliating and eradicating human and animal diseases, and the moral justification for sacrificing animals for the betterment of human life. The subjects covered in the essays include the moral status of animals and persons, the importance of animals for advancing scientific knowledge, the history of animal experimentation (and of its detractors), differing theoretical approaches of American and European animal-experimentation regulations, the heavily restrictive legislation promoted by animal rights activists, and the threats posed to research and researchers by violent animal rights zealots. Contributors include Baruch Brody, H. Tristram Englehardt, Jr., R. G. Frey, Kenneth F. Kiple and Kriemhild Cone Ornelas, Adrian R. Morrison, Charles S. Nicoll and Sharon M. Russell, Jerrold Tannenbaum, and Stuart M. Zola. This important anthology will be of interest to scientists, philosophers, individuals suffering from heritable or communicable diseases, relatives of afflicted individuals, and policymakers. Ellen Frankel Paul is deputy director of the Social Philosophy and Policy Center, professor of political science and philosophy at Bowling Green State University, and editor-in-chief of the journal Social Philosophy & Policy. Fred D. Miller, Jr., and Jeffrey Paul are, respectively, the executive director and associate director of the Social Philosophy and Policy Center; both are professors of philosophy at Bowling Green State University.
Book Synopsis Animals and Medicine by : Jack Botting
Download or read book Animals and Medicine written by Jack Botting and published by Open Book Publishers. This book was released on 2015-05-04 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.
Book Synopsis Animals and Medicine by : Adrian R Morrison
Download or read book Animals and Medicine written by Adrian R Morrison and published by . This book was released on 2020-10-09 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives-both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine-from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Book Synopsis Vaccine Analysis: Strategies, Principles, and Control by : Brian K. Nunnally
Download or read book Vaccine Analysis: Strategies, Principles, and Control written by Brian K. Nunnally and published by Springer. This book was released on 2014-11-27 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
Book Synopsis Critical Needs for Research in Veterinary Science by : National Research Council
Download or read book Critical Needs for Research in Veterinary Science written by National Research Council and published by National Academies Press. This book was released on 2005-10-18 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in veterinary science is critical for the health and well-being of animals, including humans. Food safety, emerging infectious diseases, the development of new therapies, and the possibility of bioterrorism are examples of issues addressed by veterinary science that have an impact on both human and animal health. However, there is a lack of scientists engaged in veterinary research. Too few veterinarians pursue research careers, and there is a shortage of facilities and funding for conducting research. This report identifies questions and issues that veterinary research can help to address, and discusses the scientific expertise and infrastructure needed to meet the most critical research needs. The report finds that there is an urgent need to provide adequate resources for investigators, training programs, and facilities involved in veterinary research.
Book Synopsis Animals and Medicine by : Jack Botting
Download or read book Animals and Medicine written by Jack Botting and published by . This book was released on 2015-05-04 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives-both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine-from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer. This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.
Author :Marie-Hélène Pinard Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805586191 Total Pages :455 pages Book Rating :4.8/5 (55 download)
Book Synopsis Animal Genomics for Animal Health by : Marie-Hélène Pinard
Download or read book Animal Genomics for Animal Health written by Marie-Hélène Pinard and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: "It includes a review of the state of the art in animal genomics and its applications to animal health. The contributions describe the new tools available, such as HapMaps for chicken and cattle, and show how the understanding of gene structure and function can be successfully applied to delineate the molecular mechanisms of disease and determine complex phenotypes associated with health traits. A critical evaluation of future needs and future applications of animal genomics is also presented. The integration of animal genomics in animal health research is likely to revolutionize the way scientists approach the challenges of discovering highly effective drugs and vaccines for animal diseases."--BOOK JACKET.
Book Synopsis Replacement, Reduction and Refinement of Animal Experiments in the Development and Control of Biological Products by : Fred Brown
Download or read book Replacement, Reduction and Refinement of Animal Experiments in the Development and Control of Biological Products written by Fred Brown and published by S. Karger AG (Switzerland). This book was released on 1996 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past, animal experimentation has played an important part in the development and quality control of immunobiological products. These days, however, concern about animal welfare is growing and, consequently, increasing emphasis is placed on the use of in vitro methods. This book reports the proceedings of a symposium held at the Paul Ehrlich Institute in Langen, Germany, in November 1994, at which the application of the three Rs principle - replacement, reduction and refinement of the use of animal experiments - was evaluated and recommendations were given. A review of the history of animal experimentation is followed by reports of various international organizations (including the European Pharmacopoeia and the World Health Organization) about their activities with respect to upholding the three Rs principle. It is shown that significant progress has been made in the last few years in the fields of pyrogen testing, hormones, blood products and vaccines. Several new in vitro methods for potency, efficacy and safety testing of vaccines are presented and discussed. General problems such as harmonization, statistics and validation, serological methods and cell cultures are also addressed. Demonstrating that sound science and animal welfare are not irreconcilable, this volume is a valuable resource for all those concerned with the development and manufacture of biological products.
Book Synopsis Vaccines and Diagnostics for Transboundary Animal Diseases by : J.A. Roth
Download or read book Vaccines and Diagnostics for Transboundary Animal Diseases written by J.A. Roth and published by Karger Medical and Scientific Publishers. This book was released on 2013-04-18 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transboundary animal diseases (TADs) are a major threat to livestock. They are highly contagious or transmissible, and they have the potential to cause high morbidity and mortality in both susceptible animal populations and humans. In addition, not only are TADs detrimental to national economies, they are also a serious threat to world food security. This volume presents the proceedings of an international workshop on Vaccines and Diagnostics for Transboundary Animal Diseases that was held in Ames (Iowa, USA) in 2012. Experts and scientists from academia, industry and government reviewed the current status of vaccines and diagnostics for high priority TADs, decision-making and regulatory processes for veterinary biologics, and the roles and responsibilities of government agencies. The discussions also addressed achievements and gaps in vaccine and diagnostics development for 11 important TADs as well as the translation of research findings into licensed novel vaccines and diagnostics for high-priority TADs.
Book Synopsis Animals and Medicine by : Jack Botting
Download or read book Animals and Medicine written by Jack Botting and published by . This book was released on 2015 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives-both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine-from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer. This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.
Author :National Research Council (U.S.). Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research Publisher :National Academies Press ISBN 13 : Total Pages :120 pages Book Rating :4.3/5 (91 download)
Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council (U.S.). Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council (U.S.). Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research and published by National Academies Press. This book was released on 1988 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: PATTERNS OF ANIMAL USE; ALTERNATE METHODS; REGULATORY ISSUES; POUND ANIMALS.
Book Synopsis Medicines from Animal Cell Culture by : Glyn N. Stacey
Download or read book Medicines from Animal Cell Culture written by Glyn N. Stacey and published by John Wiley & Sons. This book was released on 2007-06-29 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicines from Animal Cell Culture focuses on the use of animal cell culture, which has been used to produce human and veterinary vaccines, interferon, monoclonal antibodies and genetically engineered products such as tPA and erythropoietin. It also addresses the recent dramatic expansion in cell-based therapies, including the use of live cells for tissue regeneration and the culture of stem cells. Medicines from Animal Cell Culture: Provides comprehensive descriptions of methods for cell culture and nutrition as well as the technologies for the preservation and characterisation of both the cells and the derived products Describes the preparation of stem cells and others for use in cell-based therapies – an area of burgeoning research Includes experimental examples to indicate expected results Covers regulatory issues from the UK, the EU and the USA and reviews how these are developing around the world Addresses the key issues of standardisation and validation with chapters on GLP and GMP for cell culture processes Delivering insight into the exciting world of biological medicines and directions for further investigation into specific topics, Medicines from Animal Cell Culture is an essential resource for researchers and technicians at all levels using cell culture within the pharmaceutical, biotechnology and biomedical industries. It is of value to laboratory managers in these industries and to all those interested in this topic alike.
Book Synopsis OIE/FAO International Scientific Conference on Avian Influenza by : Alejandro Schudel
Download or read book OIE/FAO International Scientific Conference on Avian Influenza written by Alejandro Schudel and published by S. Karger AG (Switzerland). This book was released on 2006 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph comprises the proceedings of the International Conference on Avian Influenza held in Paris, France, in April 2005. Discussed were new scientific discoveries in the domain of avian influenza (AI), with special emphasis on the highly pathogenic avian influenza (HPAI). It provides important up-to-date information on the virology, epidemiology and molecular biology as well as the history of episodes of avian influenza in different parts of the world and their consequences. The publication aims at making recommendations to compare and improve the international procedures and standards related to the identification, prevention, control and elimination of AI epizootics as they are a threat to the livelihood of farmers, especially in developing countries, to public health as well as to national economies. Chief veterinary officers, animal health regulatory officials, veterinarians, poultry-raising associations, consumer associations, specialised journalists and all those who need to understand and control AI episodes will benefit from reading this book.
