Advances In Novel Drugs And Targets For Hepatic And Gastrointestinal Diseases

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Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases

Author : Yong Gao
Publisher : Frontiers Media SA
ISBN 13 : 283254374X
Total Pages : 468 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases by : Yong Gao

Download or read book Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases written by Yong Gao and published by Frontiers Media SA. This book was released on 2024-01-29 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global incidence of gastrointestinal and hepatic diseases has been gradually increasing in recent years, which seriously threatens human health and increases the economic burden. More importantly, gastrointestinal and hepatic malignancies have the highest incidence and mortality rates among all tumors, such as liver cancer, stomach cancer, colon cancer, and pancreatic cancer. There are also non-neoplastic diseases such as viral hepatitis, cirrhosis, nonalcoholic steatohepatitis, chronic atrophic gastritis, ulcerative colitis, and reflux esophageal disease that also affect patients' quality of life. Although progress has been made in the pathogenesis of gastrointestinal and hepatic diseases, and corresponding therapeutic drugs have been also developed, the specific mechanisms of the diseases are still not revealed and there is a lack of specific drugs. In view of this, this topic aims to explore new molecular mechanisms of pathogenesis and potential therapeutic agents and pharmacological effects of gastrointestinal and hepatic diseases.

Cholestatic Liver Disease

Author : Elizabeth J. Carey
Publisher : Springer
ISBN 13 : 1493910132
Total Pages : 265 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Cholestatic Liver Disease by : Elizabeth J. Carey

Download or read book Cholestatic Liver Disease written by Elizabeth J. Carey and published by Springer. This book was released on 2014-07-18 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as primary biliary cirrhosis, primary sclerosing cholangitis and cholestatic variants of drug hepatotoxicity and viral disease. New treatments, such as the development of the farnesoid X receptor agonists for the treatment of PBC, are highlighted. Current guidelines and areas of uncertainty are also covered. Additionally, new chapters have been added to reflect the changing landscape of cholestatic liver disease. Cholestatic Liver Disease, Second Edition is a concise yet comprehensive summary of the current status of the field and is of value to clinicians and researchers interested in patients with cholestatic liver disease provide that will help to guide patient management and stimulate investigative efforts.

Drug-Induced Liver Injury

Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 290 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Advances in Non-Alcoholic Fatty Liver Disease Therapeutics: Pathogenic Mechanisms and Targets

Author : Ana Blas-García
Publisher : Frontiers Media SA
ISBN 13 : 2832508588
Total Pages : 190 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Advances in Non-Alcoholic Fatty Liver Disease Therapeutics: Pathogenic Mechanisms and Targets by : Ana Blas-García

Download or read book Advances in Non-Alcoholic Fatty Liver Disease Therapeutics: Pathogenic Mechanisms and Targets written by Ana Blas-García and published by Frontiers Media SA. This book was released on 2022-12-05 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases

Author : Chi-hin Cho
Publisher : World Scientific
ISBN 13 : 9813148586
Total Pages : 458 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases by : Chi-hin Cho

Download or read book Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases written by Chi-hin Cho and published by World Scientific. This book was released on 2017-04-20 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book deals with both inflammation and cancer in a single source of publication. They are seldom grouped together although it has been known that both diseases are closely associated, particularly in the gastrointestinal tract and liver. As the book touches on two such major areas of diseases in humans, it should be of interest to a wider audience of researchers and readers. It is noted that the book combines the effort of both basic scientists and clinicians from different countries with extensive experiences in molecular biology and clinical practice to unveil the most updated picture of the pathogenesis and therapeutic strategies in the treatment of inflammation and cancer in the digestive tract. In this regard, potential pathogenic modulators and also therapeutic options are widely discussed. These types of information would definitely broaden our knowledge in better understanding these diseases.

Insights in Gastrointestinal and Hepatic Pharmacology: 2021

Author : Angelo A. Izzo
Publisher : Frontiers Media SA
ISBN 13 : 2889760650
Total Pages : 413 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Insights in Gastrointestinal and Hepatic Pharmacology: 2021 by : Angelo A. Izzo

Download or read book Insights in Gastrointestinal and Hepatic Pharmacology: 2021 written by Angelo A. Izzo and published by Frontiers Media SA. This book was released on 2022-12-05 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0123977649
Total Pages : 801 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease by : Ronald Ross Watson

Download or read book Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease written by Ronald Ross Watson and published by Academic Press. This book was released on 2012-10-22 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease provides valuable insights for those seeking nutritional treatment options for those suffering from liver and/or related gastrointestinal disease including Crohn's, allergies, and colitis among others. Information is presented on a variety of foods including herbs, fruits, soy and olive oil. This book serves as a valuable resource for researchers in nutrition, nephrology, and gastroenterology. - Addresses the most positive results from dietary interventions using bioactive foods to impact diseases of the liver and gastrointestinal system, including reduction of inflammation, improved function, and nutritional efficiency - Presents a wide range of liver and gastrointestinal diseases and provides important information for additional research - Associated information can be used to understand other diseases, which share common etiological pathways

Obesity and Cancer: Update on Etiology, Molecular Biomarkers and Biotargets, Clinical Strategies, and Epidemiology

Author : Eva Surmacz
Publisher : Frontiers Media SA
ISBN 13 : 2832533345
Total Pages : 121 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Obesity and Cancer: Update on Etiology, Molecular Biomarkers and Biotargets, Clinical Strategies, and Epidemiology by : Eva Surmacz

Download or read book Obesity and Cancer: Update on Etiology, Molecular Biomarkers and Biotargets, Clinical Strategies, and Epidemiology written by Eva Surmacz and published by Frontiers Media SA. This book was released on 2023-09-07 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunotherapy of Hepatocellular Carcinoma

Author : Tim F. Greten
Publisher : Springer
ISBN 13 : 9783319879116
Total Pages : 0 pages
Book Rating : 4.8/5 (791 download)

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Book Synopsis Immunotherapy of Hepatocellular Carcinoma by : Tim F. Greten

Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2018-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

Novel Approaches in the Treatment of Gastrointestinal and Liver Disease

Author : J. P. Galmiche
Publisher : John Libbey Eurotext
ISBN 13 : 9782742003402
Total Pages : 106 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Novel Approaches in the Treatment of Gastrointestinal and Liver Disease by : J. P. Galmiche

Download or read book Novel Approaches in the Treatment of Gastrointestinal and Liver Disease written by J. P. Galmiche and published by John Libbey Eurotext. This book was released on 2000 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Libbey Eurotext is continuing to publish the proceedings of these courses in gastroenterology organised in Europe by the world's leading specialists (and for the 6th time in France). This book offers a large view of the coming years therapeutic approaches in gastrointestinal diseases, im particular : gene therapy, organ transplant, therapy in hepatitis B and C, etc.

Recent Advances in the Pathophysiology of Gastro-intestinal and Liver Diseases

Author : J. P. Galmiche
Publisher : John Libbey Eurotext
ISBN 13 : 9782742001804
Total Pages : 288 pages
Book Rating : 4.0/5 (18 download)

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Book Synopsis Recent Advances in the Pathophysiology of Gastro-intestinal and Liver Diseases by : J. P. Galmiche

Download or read book Recent Advances in the Pathophysiology of Gastro-intestinal and Liver Diseases written by J. P. Galmiche and published by John Libbey Eurotext. This book was released on 1997 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Postgraduate Course 1997, Nantes, 3 to 7 July. In January 1997, John Libbey Eurotext first published this course organised by the European Association of Gastroenterology and Endoscopy (EAGE) for young doctors and researchers, and given by the leading European specialists in the field. As well as the annual course, EAGE also wanted to hold provincial courses with a high scientific content. This is the course given by Professors Galmiche and Gournay last July in Nantes. The aim of these lectures is to present the latest advances in basic and clinical research into gastroenterology and hepatology.

Recent Advances in Novel Therapeutic Molecules and Targets for Inflammatory Diseases

Author : Shuai Wang
Publisher : Frontiers Media SA
ISBN 13 : 2832513387
Total Pages : 134 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Recent Advances in Novel Therapeutic Molecules and Targets for Inflammatory Diseases by : Shuai Wang

Download or read book Recent Advances in Novel Therapeutic Molecules and Targets for Inflammatory Diseases written by Shuai Wang and published by Frontiers Media SA. This book was released on 2023-02-01 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel and Emerging Therapies for the Treatment of Obesity and Related Disorders

Author : Isabel Rodriguez Amado
Publisher : Frontiers Media SA
ISBN 13 : 283254875X
Total Pages : 121 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Novel and Emerging Therapies for the Treatment of Obesity and Related Disorders by : Isabel Rodriguez Amado

Download or read book Novel and Emerging Therapies for the Treatment of Obesity and Related Disorders written by Isabel Rodriguez Amado and published by Frontiers Media SA. This book was released on 2024-05-06 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity and its associated comorbidities (e.g. type II diabetes and cardiovascular disease) represent a serious challenge for healthcare systems worldwide. Obesity is a chronic disease, characterized by excessive adipose tissue mass, resulting from an imbalance between energy intake and expenditure, with growing relevance in an increasingly sedentary society. Obesity is multifactorial, where alterations in the physiology of gastrointestinal hormones, playing a key role in the interplay between the gastrointestinal system and the brain, and in the gut microbiota, contribute to the development of this disorder.

Advances in the Potential Treatments of Gastrointestinal and Liver Diseases: Addressing the Public Health Burden

Author : Mariana Jinga
Publisher : Frontiers Media SA
ISBN 13 : 2832531067
Total Pages : 268 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Advances in the Potential Treatments of Gastrointestinal and Liver Diseases: Addressing the Public Health Burden by : Mariana Jinga

Download or read book Advances in the Potential Treatments of Gastrointestinal and Liver Diseases: Addressing the Public Health Burden written by Mariana Jinga and published by Frontiers Media SA. This book was released on 2023-08-07 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Cholestatic Liver Diseases, An issue of Clinics in Liver Disease

Author : Cynthia Levy
Publisher : Elsevier Health Sciences
ISBN 13 : 0323429920
Total Pages : 225 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Advances in Cholestatic Liver Diseases, An issue of Clinics in Liver Disease by : Cynthia Levy

Download or read book Advances in Cholestatic Liver Diseases, An issue of Clinics in Liver Disease written by Cynthia Levy and published by Elsevier Health Sciences. This book was released on 2016-01-07 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Levy has secured the field’s top experts to offer the latest clinical reviews on cholestatic liver disease. The issue will include articles devoted to The Gut-Liver Axis; Update on Genetics in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis; New thoughts on IgG4 Associated Cholangitis; Cancer Risk and Surveillance in PSC; Novel Therapies for PBC; and Liver transplantation for Cholestatic Liver Diseases, to name a few. Dr. Levy’s issue will be the most current authority on cholestatic liver disease.

Fundamentals of Drug Delivery

Author : Heather A. E. Benson
Publisher : John Wiley & Sons
ISBN 13 : 1119769604
Total Pages : 580 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Fundamentals of Drug Delivery by : Heather A. E. Benson

Download or read book Fundamentals of Drug Delivery written by Heather A. E. Benson and published by John Wiley & Sons. This book was released on 2021-10-12 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Hepatotoxicity

Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 850 pages
Book Rating : 4.7/5 (195 download)

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Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.